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Journal of Biological Chemistry, ISSN 0021-9258, 10/2003, Volume 278, Issue 41, pp. 39735 - 39746
CIN85 is a multidomain adaptor protein implicated in Cbl-mediated down-regulation of receptor tyrosine kinases. CIN85 binding to Cbl is increased after growth... 
BINDING MOTIF | PHOSPHORYLATION | C-CBL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CIN85 | SH3 DOMAINS | TYROSINE KINASES | LIGAND | ADAPTER PROTEIN | PLASMA-MEMBRANE | EGF RECEPTOR | Consensus Sequence | Receptor, Epidermal Growth Factor - genetics | Humans | Retroviridae Proteins, Oncogenic - metabolism | Molecular Sequence Data | Phosphoproteins - metabolism | Phosphoproteins - chemistry | Endocytosis | Receptor, Epidermal Growth Factor - metabolism | Proto-Oncogene Proteins c-cbl | Carrier Proteins - chemistry | Binding Sites | CHO Cells | Oncogene Protein v-cbl | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Cricetinae | Retroviridae Proteins, Oncogenic - chemistry | Down-Regulation | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Phosphoproteins - genetics | Amino Acid Motifs | Arginine - chemistry | Proline - chemistry | src Homology Domains | Sequence Homology, Amino Acid | Ubiquitin-Protein Ligases | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Animals | Carrier Proteins - metabolism | Retroviridae Proteins, Oncogenic - genetics | In Vitro Techniques | Arginine/chemistry | Medical and Health Sciences | Medicin och hälsovetenskap | Phosphoproteins/chemistry/genetics/metabolism | Receptor; Epidermal Growth Factor/genetics/metabolism | Adaptor Proteins; Signal Transducing | Proline/chemistry | Recombinant Proteins/chemistry/genetics/metabolism | Sequence Homology; Amino Acid | Carrier Proteins/chemistry/genetics/metabolism | Retroviridae Proteins; Oncogenic/chemistry/genetics/metabolism
Journal Article
Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7343, pp. 361 - 365
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus... 
HIV-1 | CYCLOPHILIN-A | UNANCHORED POLYUBIQUITIN CHAINS | TRIM5-ALPHA PROTEIN | RECOGNITION | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | RESISTANCE | INFECTION | RESTRICTION | Capsid - chemistry | Receptors, Pattern Recognition - immunology | Humans | Ubiquitin - metabolism | NF-kappa B - metabolism | Lipopolysaccharides - immunology | Transcription Factor AP-1 - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | HIV-1 - chemistry | HEK293 Cells | Carrier Proteins - immunology | Cell Line | Retroviridae - chemistry | Ubiquitin-Protein Ligases - metabolism | Retroviridae - immunology | MAP Kinase Kinase Kinases - metabolism | Transcription Factors - metabolism | Capsid - immunology | Carrier Proteins - genetics | Immunity, Innate - immunology | HIV-1 - immunology | Carrier Proteins - metabolism | Signal Transduction - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Lipopolysaccharides - pharmacology | Protein Binding | Enzyme Activation | Ubiquitin-Protein Ligases - genetics | Signal transduction | Efficiency | RNA polymerase | Pattern recognition | Kinases | Evacuations & rescues | Immune system | HIV-1/immunology | Capsid/immunology | Life Sciences | MAP Kinase Kinase Kinases/metabolism | Carrier Proteins/immunology | Immunology | Transcription Factors/metabolism | Capsid/chemistry | HIV-1/chemistry | Ubiquitin/metabolism | Receptors, Pattern Recognition/immunology | Retroviridae/chemistry | Ubiquitin-Protein Ligases/immunology | Ubiquitin-Conjugating Enzymes/metabolism | HumansImmunity, Innate/immunology | Lipopolysaccharides/pharmacology | Signal Transduction/drug effects | Retroviridae/immunology | Transcription Factor AP-1/metabolism | Lipopolysaccharides/immunology | Ubiquitin-Protein Ligases/metabolism | Carrier Proteins/genetics | Signal Transduction/immunology | NF-kappa B/metabolism | Ubiquitin-Protein Ligases/genetics | Carrier Proteins/metabolism | Receptors, Pattern Recognition/metabolism
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2010, Volume 432, Issue 3, pp. 525 - 534
The adaptor protein ALIX [ALG-2 (apoptosis-linked-gene-2 product)-interacting protein X] links retroviruses to ESCRT (endosomal sorting complex required for... 
Tumour susceptibility gene 101 protein (TSG101) | ALG-2 (apoptosis-linked-gene-2 product)-interacting protein X (ALIX) | Autoinhibition | Src | Charged multivesicular body protein 4 (CHMP4) | Retroviral budding | Intramolecular interaction | intramolecular interaction | HIV-1 | charged multivesicular body protein 4 (CHMP4) | ALIX/AIP1 | retroviral budding | PHOSPHORYLATION | INFECTIOUS-ANEMIA VIRUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | autoinhibition | BRO1 DOMAIN | MULTIVESICULAR BODY BIOGENESIS | CYTOKINESIS | tumour susceptibility gene 101 protein (TSG101) | STRUCTURAL BASIS | III COMPLEX | BINDING | Oncogene Protein pp60(v-src) - metabolism | Transcription Factors - chemistry | Vesicular Transport Proteins - metabolism | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Proline-Rich Protein Domains - physiology | Recombinant Fusion Proteins - metabolism | Gene Products, gag - chemistry | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Oncogene Protein pp60(v-src) - chemistry | HEK293 Cells | Cell Cycle Proteins - genetics | Retroviridae Proteins - chemistry | Cell Membrane - metabolism | Endosomal Sorting Complexes Required for Transport - chemistry | Protein Interaction Domains and Motifs | Calcium-Binding Proteins - chemistry | Recombinant Proteins - metabolism | Gene Products, gag - genetics | Endosomal Sorting Complexes Required for Transport - metabolism | Recombinant Proteins - chemistry | Mutant Proteins - metabolism | Oncogene Protein pp60(v-src) - genetics | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Retroviridae Proteins - genetics | Gene Products, gag - metabolism | Transcription Factors - metabolism | Infectious Anemia Virus, Equine - physiology | Retroviridae Proteins - metabolism | Calcium-Binding Proteins - physiology | Mutant Proteins - chemistry | Virus Release - physiology | Hydrophobic and Hydrophilic Interactions | Cell Cycle Proteins - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Calcium-Binding Proteins - genetics | TSG101 | ALIX | CHMP4
Journal Article
Journal Article
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2008, Volume 180, Issue 2, pp. 341 - 355
Journal Article