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Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7343, pp. 361 - 365
TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus... 
HIV-1 | CYCLOPHILIN-A | UNANCHORED POLYUBIQUITIN CHAINS | TRIM5-ALPHA PROTEIN | RECOGNITION | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | RESISTANCE | INFECTION | RESTRICTION | Capsid - chemistry | Receptors, Pattern Recognition - immunology | Humans | Ubiquitin - metabolism | NF-kappa B - metabolism | Lipopolysaccharides - immunology | Transcription Factor AP-1 - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Ubiquitin-Protein Ligases - immunology | HIV-1 - chemistry | HEK293 Cells | Carrier Proteins - immunology | Cell Line | Retroviridae - chemistry | Ubiquitin-Protein Ligases - metabolism | Retroviridae - immunology | MAP Kinase Kinase Kinases - metabolism | Transcription Factors - metabolism | Capsid - immunology | Carrier Proteins - genetics | Immunity, Innate - immunology | HIV-1 - immunology | Carrier Proteins - metabolism | Signal Transduction - drug effects | Ubiquitin-Conjugating Enzymes - metabolism | Lipopolysaccharides - pharmacology | Protein Binding | Enzyme Activation | Ubiquitin-Protein Ligases - genetics | Signal transduction | Efficiency | RNA polymerase | Pattern recognition | Kinases | Evacuations & rescues | Immune system | HIV-1/immunology | Capsid/immunology | Life Sciences | MAP Kinase Kinase Kinases/metabolism | Carrier Proteins/immunology | Immunology | Transcription Factors/metabolism | Capsid/chemistry | HIV-1/chemistry | Ubiquitin/metabolism | Receptors, Pattern Recognition/immunology | Retroviridae/chemistry | Ubiquitin-Protein Ligases/immunology | Ubiquitin-Conjugating Enzymes/metabolism | HumansImmunity, Innate/immunology | Lipopolysaccharides/pharmacology | Signal Transduction/drug effects | Retroviridae/immunology | Transcription Factor AP-1/metabolism | Lipopolysaccharides/immunology | Ubiquitin-Protein Ligases/metabolism | Carrier Proteins/genetics | Signal Transduction/immunology | NF-kappa B/metabolism | Ubiquitin-Protein Ligases/genetics | Carrier Proteins/metabolism | Receptors, Pattern Recognition/metabolism
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2007, Volume 179, Issue 10, pp. 6808 - 6819
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2017, Volume 25, Issue 5, pp. 1117 - 1124
Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T lymphocytes to target chosen antigens. The targeting of CD19, a cell surface... 
genome editing | vectors | T cells | CAR | genetic engineering | immunotherapy | MEDICINE, RESEARCH & EXPERIMENTAL | ADENOSINE-DEAMINASE | REVERSE-TRANSCRIPTASE | ZINC-FINGER NUCLEASES | B-CELL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | IMMUNODEFICIENCY-VIRUS TYPE-1 | HUMAN T-LYMPHOCYTES | PERIPHERAL-BLOOD LYMPHOCYTES | RETROVIRAL VECTOR | ADOPTIVE IMMUNOTHERAPY | HEMATOPOIETIC STEM | Cell- and Tissue-Based Therapy - methods | Immunotherapy - methods | Leukemia - pathology | Lentivirus - immunology | Protein Engineering - methods | Humans | Mutant Chimeric Proteins - genetics | Antigens, CD19 - genetics | T-Lymphocytes - classification | Cell Engineering - methods | Lymphoma - therapy | Retroviridae - genetics | Lentivirus - genetics | Lymphoma - pathology | Receptors, Antigen, T-Cell - immunology | Leukemia - genetics | Antigens, CD19 - immunology | Gene Expression | Genetic Vectors - chemistry | Genetic Vectors - immunology | Lymphoma - immunology | Leukemia - therapy | Lymphoma - genetics | Retroviridae - immunology | T-Lymphocytes - cytology | Leukemia - immunology | Mutant Chimeric Proteins - immunology | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | CRISPR | Antigens | CD19 antigen | Leukemia | T cell receptors | Lymphocytes T | Genomes | Biology | Vectors (Biology) | Cell surface | Lymphocytes | Immunotherapy | Cell cycle | Physiology | Lymphomas | Genetic engineering | Manufacturing | Gene therapy | Tumors | Cancer | Review
Journal Article
Journal Article
Journal Article
Gene Therapy, ISSN 0969-7128, 05/2013, Volume 20, Issue 5, pp. 575 - 580
Transforming growth factor beta (TGF-beta) is a cytokine with complex biological functions that may involve tumor promotion or tumor suppression. It has been... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTITUMOR-ACTIVITY | antigen-specific T cell | BREAST-CANCER | TGF-beta | GROWTH-FACTOR-BETA | SOLUBLE BETAGLYCAN | IMMUNOTHERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | II RECEPTOR | GENETICS & HEREDITY | ESTABLISHED MELANOMA | DIFFERENTIATION | AUTOIMMUNE-DISEASE | adoptive T-cell therapy | LYMPHOCYTES | Recombinant Fusion Proteins - immunology | Receptors, Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - immunology | Humans | Signal Transduction - immunology | Immunoglobulin Fc Fragments - immunology | Melanoma, Experimental - immunology | Receptor, Transforming Growth Factor-beta Type II | Retroviridae - genetics | Immunoglobulin G - immunology | Immunotherapy | Transforming Growth Factor beta - antagonists & inhibitors | Transforming Growth Factor beta - immunology | Melanoma, Experimental - therapy | Protein-Serine-Threonine Kinases - genetics | Treatment Outcome | Signal Transduction - genetics | Antigen-Presenting Cells - immunology | Animals | Apoptosis - immunology | Genetic Engineering | Immunoglobulin G - genetics | Melanoma, Experimental - genetics | Transforming Growth Factor beta - genetics | T-Lymphocytes - cytology | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Protein-Serine-Threonine Kinases - immunology | T-Lymphocytes - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Genetic Vectors | Immunoglobulin Fc Fragments - genetics | TGF-β
Journal Article