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Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2015, Volume 58, Issue 4, pp. 1915 - 1928
Journal Article
Science, ISSN 0036-8075, 11/2014, Volume 346, Issue 6212, pp. 1000 - 1003
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2016, Volume 59, Issue 17, pp. 7991 - 8007
We designed and synthesized a series of human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitors (NNRTIs) with a... 
BEARING BRIDGEHEAD NITROGEN | CHEMISTRY, MEDICINAL | ENTRANCE CHANNEL | MUTANT VIRUSES | ENHANCED SOLUBILITY | PRELIMINARY SAR | COLORIMETRIC ASSAY | BIOLOGICAL EVALUATION | NNRTI BINDING POCKET | CRYSTAL-STRUCTURES | ETRAVIRINE TMC125 | Anti-HIV Agents - pharmacology | Pyrimidines - chemical synthesis | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Drug Resistance, Viral | Reverse Transcriptase Inhibitors - pharmacology | Male | Structure-Activity Relationship | Anti-HIV Agents - chemical synthesis | Pyrimidines - chemistry | Reverse Transcriptase Inhibitors - chemistry | Reverse Transcriptase Inhibitors - chemical synthesis | Reverse Transcriptase Inhibitors - pharmacokinetics | Sulfonamides - chemistry | Heterocyclic Compounds, 2-Ring - chemistry | Thiophenes - pharmacology | Heterocyclic Compounds, 2-Ring - pharmacokinetics | Pyrimidines - pharmacology | HIV-1 - genetics | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Sulfonamides - pharmacokinetics | Heterocyclic Compounds, 2-Ring - pharmacology | Sulfonamides - chemical synthesis | Thiophenes - chemical synthesis | Thiophenes - pharmacokinetics | Anti-HIV Agents - chemistry | Animals | Anti-HIV Agents - pharmacokinetics | Cell Line, Tumor | Pyrimidines - pharmacokinetics | HIV-1 - enzymology | Mice | Molecular Docking Simulation | Mutation | Thiophenes - chemistry | Heterocyclic Compounds, 2-Ring - chemical synthesis
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2012, Volume 55, Issue 23, pp. 10601 - 10609
Journal Article
Journal Article