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Cancer Cell, ISSN 1535-6108, 12/2013, Volume 24, Issue 6, pp. 710 - 724
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 02/2014, Volume 14, Issue 1, pp. 139 - 139
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e110340 - e110340
Rhabdomyosarcoma is the most frequent soft tissue sarcoma in children and adolescents, with a high rate of relapse that dramatically affects the clinical... 
V-ATPASE | ACIDIC VESICLES | ACRIDINE-ORANGE | BONE SARCOMAS | SIDE POPULATION CELLS | HUMAN OSTEOSARCOMA | MULTIDISCIPLINARY SCIENCES | RESISTANCE | IDENTIFICATION | EXPRESSION | P-GLYCOPROTEIN | Lysosomes - drug effects | Proton Pump Inhibitors - pharmacology | Lysosomes - chemistry | Neoplasm Invasiveness | Neoplastic Stem Cells - drug effects | Humans | Rhabdomyosarcoma, Embryonal - drug therapy | Proton Pump Inhibitors - therapeutic use | Vacuolar Proton-Translocating ATPases - metabolism | Cell Movement - drug effects | Lysosomes - metabolism | Cell Line, Tumor | Neoplastic Stem Cells - pathology | Doxorubicin - pharmacology | Molecular Targeted Therapy - methods | Rhabdomyosarcoma, Embryonal - pathology | Hydrogen-Ion Concentration | Chemotherapy | Sarcoma | Radiotherapy | Adenosine triphosphatase | Stem cells | Cancer | Adolescence | Toxicity | Oct-4 protein | Radiation | Rhabdomyosarcoma | Acidification | Cytotoxicity | Neuroblastoma | Spheres | Autophagy | Cancer therapies | Doxorubicin | Metastases | Genotype & phenotype | Surgery | Children | Adolescents | Growth factors | Drug dosages | H+-transporting ATPase | Multiagent systems | Invasiveness | Multidrug resistance | Minimal residual disease | Soft tissue sarcoma | siRNA | Acidity | Radiation therapy | Medicine | Omeprazole | Hypoxia | Tumors | Index Medicus
Journal Article
Carcinogenesis, ISSN 0143-3334, 03/2015, Volume 36, Issue 9, pp. 1071 - 1083
Journal Article
Journal Article
International Journal of Radiation Oncology Biology Physics, ISSN 0360-3016, 06/2012, Volume 83, Issue 2, pp. 720 - 726
Purpose: To analyze the effect of reduced-dose radiotherapy on local control in children with low-risk rhabdomyosarcoma (RMS) treated in the Children's... 
Radiotherapy | Local control | Low risk | Rhabdomyosarcoma | PARAMENINGEAL RHABDOMYOSARCOMA | INTERNATIONAL SOCIETY | INTERGROUP-RHABDOMYOSARCOMA | NONMETASTATIC RHABDOMYOSARCOMA | SURGICAL-MANAGEMENT | FAILURE | RADIATION-THERAPY | STUDY-IV | GROUP-III PATIENTS | ONCOLOGY | PATIENT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Lymph Node Excision | Prostatic Neoplasms - radiotherapy | Age Factors | Humans | Child, Preschool | Infant | Male | Rhabdomyosarcoma, Embryonal - surgery | Neoplasm, Residual | Young Adult | Rhabdomyosarcoma, Embryonal - secondary | Treatment Failure | Adult | Female | Urogenital Neoplasms - drug therapy | Orbital Neoplasms - surgery | Child | Infant, Newborn | Orbital Neoplasms - radiotherapy | Prostatic Neoplasms - drug therapy | Rhabdomyosarcoma, Embryonal - pathology | Quality Control | Prostatic Neoplasms - pathology | Drug Administration Schedule | Prostatic Neoplasms - surgery | Head and Neck Neoplasms - drug therapy | Orbital Neoplasms - pathology | Urogenital Neoplasms - pathology | Orbital Neoplasms - drug therapy | Lymphatic Metastasis | Rhabdomyosarcoma, Embryonal - drug therapy | Tumor Burden | Head and Neck Neoplasms - pathology | Head and Neck Neoplasms - radiotherapy | Radiotherapy Dosage - standards | Urogenital Neoplasms - radiotherapy | Adolescent | Combined Modality Therapy - methods | Urogenital Neoplasms - surgery | Rhabdomyosarcoma, Embryonal - radiotherapy | Second-Look Surgery | Head and Neck Neoplasms - surgery | Index Medicus | SURGERY | PATIENTS | NEOPLASMS | LYMPH NODES | FAILURES | RADIOLOGY AND NUCLEAR MEDICINE | ENDOXAN | RADIATION DOSES | RADIOTHERAPY | CHILDREN | CONTROL | HAZARDS
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0144320 - e0144320
Embryonal rhabdomyosarcoma (ERMS) is the most common soft tissue cancer in children. The prognosis of patients with relapsed or metastatic disease remains... 
HDAC INHIBITORS | ALVEOLAR | IN-VITRO | THERAPY | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | GROWTH | RECEPTOR | DIFFERENTIATION | CELL-LINES | EXPRESSION | Zebrafish Proteins - biosynthesis | Ephrin-B1 - genetics | Histone Deacetylases - genetics | Neoplasm Proteins - biosynthesis | Humans | Zebrafish Proteins - antagonists & inhibitors | Histone Deacetylases - metabolism | Rhabdomyosarcoma, Embryonal - drug therapy | Down-Regulation - drug effects | Receptor, Notch1 - biosynthesis | Zebrafish - genetics | Rhabdomyosarcoma, Embryonal - genetics | Animals | Rhabdomyosarcoma, Embryonal - metabolism | Ephrin-B1 - biosynthesis | Zebrafish - metabolism | Histone Deacetylase Inhibitors - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Zebrafish Proteins - genetics | Neoplasm Proteins - genetics | Receptor, Notch1 - genetics | Epigenetic inheritance | Care and treatment | Analysis | Rhabdomyosarcoma | Histones | Research | Children | Carcinogenesis | Health aspects | Risk factors | Health sciences | Histone deacetylase | Chromatin | Immunoprecipitation | Pathogenesis | Genomes | Metastases | Pathways | Cell cycle | Occupational health | Trichostatin A | Tumorigenesis | Bioinformatics | Drug dosages | Medical research | Hydroxamic acid | Gene expression | Patients | Pathology | Molecular modelling | Inhibitors | Epigenetics | Mutation | Aberration | Differentiation | Cell migration | Cancer | Index Medicus
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2013, Volume 49, Issue 16, pp. 3462 - 3470
Abstract Background Rhabdomyosarcoma (RMS) is an aggressive soft tissue tumour mainly affecting children and adolescents. Since survival of high-risk patients... 
Hematology, Oncology and Palliative Medicine | Anaplastic lymphoma kinase receptor | Insulin-like growth factor 1 receptor | Embryonal rhabdomyosarcoma | Targeted treatment | In vitro | Alveolar rhabdomyosarcoma | METASTATIC RHABDOMYOSARCOMA | MONOCLONAL-ANTIBODY | MECHANISMS | COMBINATION | ONCOLOGY | RESISTANCE | INTERGROUP | OUTCOMES | INHIBITOR | IGF-1 RECEPTOR | EXPRESSION | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Middle Aged | Child, Preschool | Infant | Molecular Targeted Therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Dose-Response Relationship, Drug | Young Adult | Netherlands | Rhabdomyosarcoma, Alveolar - mortality | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Rhabdomyosarcoma, Alveolar - pathology | Child | Infant, Newborn | Rhabdomyosarcoma, Embryonal - pathology | Rhabdomyosarcoma, Alveolar - drug therapy | Cell Survival - drug effects | Rhabdomyosarcoma, Embryonal - enzymology | Kaplan-Meier Estimate | Rhabdomyosarcoma, Embryonal - mortality | Rhabdomyosarcoma, Embryonal - drug therapy | Chi-Square Distribution | Receptor Protein-Tyrosine Kinases - metabolism | Drug Synergism | Rhabdomyosarcoma, Alveolar - enzymology | Adolescent | Cell Line, Tumor | Aged | Protein Kinase Inhibitors - pharmacology | Lymphomas | Index Medicus
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 2, pp. 635 - 642
Purpose To report the clinical outcome and late side effect profile of proton radiotherapy in the treatment of children with parameningeal rhabdomyosarcoma... 
Radiology | Hematology, Oncology and Palliative Medicine | Conformal radiotherapy | Late effects | Proton radiotherapy | Parameningeal rhabdomyosarcoma | Pediatric | NECK RHABDOMYOSARCOMA | HEAD | INTERGROUP RHABDOMYOSARCOMA | INTERNATIONAL-SOCIETY | INTENSITY-MODULATED RADIOTHERAPY | NONMETASTATIC RHABDOMYOSARCOMA | SOFT-TISSUE | CHILDREN | CHILDHOOD-CANCER | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PEDIATRIC-ONCOLOGY | Follow-Up Studies | Protons - adverse effects | Humans | Child, Preschool | Protons - therapeutic use | Infant | Male | Radiotherapy - adverse effects | Organ Sparing Treatments - methods | Rhabdomyosarcoma - radiotherapy | Meningeal Neoplasms - drug therapy | Rhabdomyosarcoma, Alveolar - mortality | Massachusetts | Female | Rhabdomyosarcoma - drug therapy | Child | Rhabdomyosarcoma - mortality | Rhabdomyosarcoma, Alveolar - drug therapy | Rhabdomyosarcoma, Alveolar - radiotherapy | Treatment Outcome | Rhabdomyosarcoma, Embryonal - mortality | Rhabdomyosarcoma, Embryonal - drug therapy | Meningeal Neoplasms - mortality | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Meningeal Neoplasms - radiotherapy | Rhabdomyosarcoma, Embryonal - radiotherapy | Radiotherapy | Medical colleges | Nuclear radiation | Index Medicus | DIAGNOSIS | PATIENTS | NEOPLASMS | FAILURES | PHOTONS | TEETH | RADIATION DOSES | CARIES | HISTOLOGY | PROTONS | SINUSES | MEDICAL RECORDS | NOSE | RADIATION DOSE UNITS | RADIOLOGY AND NUCLEAR MEDICINE | PEDIATRICS | RADIOTHERAPY | SIDE EFFECTS | COBALT | CONTROL
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 10/2017, Volume 64, Issue 10, p. n/a
Journal Article
British Journal of Cancer, ISSN 0007-0920, 09/2009, Volume 101, Issue 5, pp. 774 - 781
BACKGROUND: Interruption of the role of p53s as a tumour suppressor by MDM2 may be one of the mechanisms by which cancer cells evade current therapy. Blocking... 
MDM2 | Small molecule inhibitors | Rhabdomyosarcoma | Apoptosis | P53 | small molecule inhibitors | P53-MDM2 INTERACTION | ONCOPROTEIN | DOMAIN | PROTEIN | INTERGROUP RHABDOMYOSARCOMA | apoptosis | CANCER | TUMOR-SUPPRESSOR P53 | p53 | PEDIATRIC RHABDOMYOSARCOMA