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Fish and Shellfish Immunology, ISSN 1050-4648, 03/2015, Volume 43, Issue 1, pp. 13 - 24
As an intracellular pattern recognition receptor (PRR), the retinoic acid-inducible gene-I (RIG-I) is responsible for the recognition of cytosolic viral... 
Variant | Retinoic acid-inducible gene-I | Type I IFN production | RIG-Ib/MAVS-mediated signaling pathway | Mitochondrial antiviral signaling protein | ACTIVATION | INNATE IMMUNE-RESPONSE | RIG-lb/MAVS-mediated signaling pathway | IMMUNOLOGY | RNA VIRUSES | IDENTIFICATION | PATHOGEN RECOGNITION | VIRAL-INFECTION | MDA5 | FISHERIES | INDUCIBLE GENE-I | MARINE & FRESHWATER BIOLOGY | VETERINARY SCIENCES | RECEPTORS | LGP2 | DNA, Complementary - genetics | Molecular Sequence Data | Antiviral Agents - metabolism | RNA, Messenger - metabolism | Rhabdoviridae Infections - virology | Enterobacteriaceae Infections - genetics | Rhabdoviridae - physiology | Cloning, Molecular | Interferon Type I - metabolism | Amino Acid Sequence | Cell Line | Promoter Regions, Genetic | Rhabdoviridae Infections - veterinary | Rhabdoviridae Infections - metabolism | Signal Transduction | Zebrafish Proteins - chemistry | Enterobacteriaceae Infections - metabolism | Enterobacteriaceae Infections - veterinary | Zebrafish Proteins - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Zebrafish | Fish Diseases - genetics | Sequence Alignment - veterinary | Edwardsiella tarda - physiology | Animals | Fish Diseases - virology | Rhabdoviridae Infections - genetics | Enterobacteriaceae Infections - virology | Interferon Type I - genetics | Zebrafish Proteins - genetics | DNA, Complementary - metabolism | Fish Diseases - metabolism | Virus diseases | Health aspects | Fishes | Tretinoin
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e111084
Among the essential metabolic functions of the liver, in mammals, a role as mediator of systemic and local innate immunity has also been reported. Although the... 
B-CELLS | ACUTE-PHASE RESPONSE | IMMUNOLOGICAL ORGAN | SINUSOIDAL ENDOTHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | ONCORHYNCHUS-MYKISS | SERUM-AMYLOID-A | FISH | INNATE | RECEPTOR | EXPRESSION | Liver - virology | Liver - pathology | Spleen - immunology | Glycoproteins - metabolism | Viral Proteins - metabolism | Leukocytes - immunology | Rhabdoviridae Infections - virology | Liver - immunology | Fish Diseases - immunology | Female | Transcription, Genetic | Oncorhynchus mykiss - virology | Novirhabdovirus - immunology | Oncorhynchus mykiss - immunology | Receptors, Chemokine - genetics | Spleen - pathology | Glycoproteins - genetics | Oncorhynchus mykiss - metabolism | Rhabdoviridae Infections - veterinary | Rhabdoviridae Infections - metabolism | Liver - metabolism | Receptors, Chemokine - metabolism | Viral Proteins - genetics | Chemokines - genetics | Animals | Fish Diseases - virology | Rhabdoviridae Infections - immunology | Leukocytes - virology | Receptors, Pattern Recognition - genetics | Chemokines - metabolism | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Fish Diseases - metabolism | Immunohistochemistry | Immune response | Trout | Septicemia | Analysis | Fishes | Liver | B cells | Biological response modifiers | T cells | Health aspects | Immunoglobulin M | Flow cytometry | Hemorrhagic septicemia | Populations | Transcription | CD8 antigen | Genes | Gene regulation | Viruses | Innate immunity | Lymphocytes T | Infections | Immunoglobulin D | Immunity | Hemorrhage | Receptors | Lymphocytes | Rodents | Fish | Perforin | Immune system | Spleen | Salmon | CD3 antigen | T cell receptors | Pattern recognition | CD4 antigen | White blood cells | Cytometry | Major histocompatibility complex | Lymphocytes B | Hepatocytes | Interferon | Histocompatibility | Chemokines | Viral infections
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2013, Volume 191, Issue 12, pp. 5959 - 5972
TNF-α is a cytokine involved in systemic inflammation and regulation of immune cells. It is produced chiefly by activated macrophages as a membrane or secreted... 
Recombinant Fusion Proteins - pharmacology | Species Specificity | Tumor Necrosis Factor-alpha - genetics | Antimicrobial Cationic Peptides - biosynthesis | Molecular Sequence Data | Phylogeny | Protein Isoforms - isolation & purification | Recombinant Fusion Proteins - metabolism | Fishes - immunology | Yersinia Infections - metabolism | Yersinia Infections - veterinary | Protein Isoforms - chemistry | Yersinia ruckeri | Base Sequence | Phytohemagglutinins - pharmacology | Fish Diseases - immunology | Novirhabdovirus | Antimicrobial Cationic Peptides - genetics | Oncorhynchus mykiss - immunology | Cytokines - genetics | Oncorhynchus mykiss - metabolism | Amino Acid Sequence | Cell Line | Fishes - genetics | Poly I-C - pharmacology | Rhabdoviridae Infections - veterinary | Rhabdoviridae Infections - metabolism | Oncorhynchus mykiss - genetics | Organ Specificity | Tumor Necrosis Factor-alpha - isolation & purification | Protein Isoforms - physiology | Gene Expression Regulation - drug effects | Sequence Homology, Amino Acid | Macrophages - metabolism | Sequence Alignment | Animals | Tumor Necrosis Factor-alpha - chemistry | Rhabdoviridae Infections - immunology | Lipopolysaccharides - pharmacology | Tumor Necrosis Factor-alpha - physiology | Tumor Necrosis Factor-alpha - classification | Peptidoglycan - pharmacology | Yersinia Infections - immunology | Cytokines - biosynthesis | Interferon-gamma - pharmacology | Fish Diseases - metabolism
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 2008, Volume 28, Issue 5, pp. 651 - 661
Journal Article
Journal Article
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 07/2017, Volume 66, pp. 360 - 371
Melanoma differentiation-associated gene 5 (MDA5) belongs to RIG-I like receptor (RLR) family, which detects cytosolic viral RNA component in immune response.... 
Innate immunity | Black carp | LGP2 | MDA5 | DOUBLE-STRANDED-RNA | HELICASE LGP2 | INTERFERON-STIMULATED GENES | INNATE IMMUNE-RESPONSE | SEA PERCH | RIG-I | IMMUNOLOGY | IDENTIFICATION | FISHERIES | MARINE & FRESHWATER BIOLOGY | MELANOMA DIFFERENTIATION | VETERINARY SCIENCES | LATEOLABRAX-JAPONICUS | PATTERN-RECOGNITION RECEPTORS | Reoviridae Infections - genetics | RNA Helicases - metabolism | DNA, Complementary - genetics | Phylogeny | RNA, Messenger - metabolism | Reoviridae Infections - virology | Fish Proteins - genetics | Rhabdoviridae Infections - virology | Reoviridae - physiology | Rhabdoviridae - physiology | Cloning, Molecular | Fish Diseases - immunology | RNA Helicases - genetics | Interferons - genetics | DEAD-box RNA Helicases - metabolism | DEAD-box RNA Helicases - chemistry | Amino Acid Sequence | Rhabdoviridae Infections - veterinary | Fish Proteins - chemistry | Fish Proteins - immunology | RNA, Messenger - genetics | Reoviridae Infections - immunology | Fish Proteins - metabolism | Carps | Reoviridae Infections - veterinary | Signal Transduction - genetics | Immunity, Innate | Sequence Alignment - veterinary | DEAD-box RNA Helicases - genetics | Animals | Fish Diseases - virology | Rhabdoviridae Infections - immunology | Rhabdoviridae Infections - genetics | Interferons - metabolism | DNA, Complementary - metabolism | Antiviral agents | Carp | RNA | Developmental biology | Fishes | Melanoma | Skin | Liver
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2013, Volume 9, Issue 1, p. e1003098
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2012, Volume 109, Issue 16, pp. 6175 - 6180
Dendritic cells (DC) are antigen-presenting cells found in both lymphoid and nonlymphoid organs, including the brain (bDC) of Cd11c/eyfp transgenic C57BL/6... 
T lymphocytes | Antigens | Brain | Phenotypes | Dendritic cells | Memory interference | Neurons | Antigen presenting cells | Infections | Ova | Antigen presentation | Neuroinflammation | MOUSE-BRAIN | antigen presentation | MULTIDISCIPLINARY SCIENCES | MICROGLIAL CELLS | INTERFERON | neuroinflammation | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | CHOROID-PLEXUS | STEADY-STATE | MICE | VESICULAR STOMATITIS-VIRUS | MIXED LEUKOCYTE REACTION | Antigens, CD - immunology | Receptor, Macrophage Colony-Stimulating Factor - immunology | Encephalitis, Viral - genetics | Leukocyte Common Antigens - metabolism | Ovalbumin - immunology | Dendritic Cells - immunology | Brain - virology | Olfactory Bulb - metabolism | Olfactory Bulb - immunology | Receptor, Macrophage Colony-Stimulating Factor - metabolism | Antigens, CD - metabolism | Brain - metabolism | Leukocyte Common Antigens - immunology | Flow Cytometry | T-Lymphocytes - metabolism | Integrin alpha Chains - immunology | Antigens, Ly - metabolism | Encephalitis, Viral - metabolism | Dendritic Cells - metabolism | Rhabdoviridae Infections - metabolism | CD11b Antigen - immunology | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Cells, Cultured | Mice, Transgenic | Integrin alpha Chains - metabolism | Receptors, Chemokine - immunology | Antigen Presentation - immunology | Microscopy, Confocal | Animals | Antigens, Ly - immunology | Rhabdoviridae Infections - immunology | Rhabdoviridae Infections - genetics | Luminescent Proteins - genetics | T-Lymphocytes - immunology | Mice | CD11b Antigen - metabolism | Brain - immunology | Encephalitis, Viral - immunology | Vesicular stomatitis Indiana virus - immunology | Luminescent Proteins - metabolism | Biological Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2011, Volume 286, Issue 6, pp. 4517 - 4524
Journal Article
Journal Article