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1. Full Text Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5–grass pollen tablet for seasonal allergic rhinitis
by Didier, Alain, MD and Malling, Hans-Jörgen, MD and Worm, Margitta, MD and Horak, Friedrich, MD and Jäger, Siegfried, PhD and Montagut, Armelle, PhD and André, Claude, MD and de Beaumont, Olivier, MD and Melac, Michel, MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2007, Volume 120, Issue 6, pp. 1338 - 1345
Background Sublingual immunotherapy is well tolerated and data suggest its effectiveness for the treatment of allergic rhinitis in adults, but it lacks optimum... 
Allergy and Immunology | allergen | placebo-controlled trial | dose response | allergic rhinoconjunctivitis | grass pollen tablet | grass pollen allergy | Sublingual immunotherapy | randomized | double-blind | METAANALYSIS | RANDOMIZED CONTROLLED-TRIAL | IMMUNOLOGY | SWALLOW IMMUNOTHERAPY | CHILDREN | ALLERGY | RHINOCONJUNCTIVITIS | ASTHMA | sublingual immunotherapy | EXTRACT | Poaceae - immunology | Poaceae - adverse effects | Administration, Sublingual | Double-Blind Method | Drug Administration Schedule | Tablets | Humans | Middle Aged | Antigens, Plant - immunology | Male | Pollen - adverse effects | Antigens, Plant - adverse effects | Pollen - immunology | Conjunctivitis, Allergic - therapy | Rhinitis, Allergic, Seasonal - diagnosis | Antigens, Plant - therapeutic use | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - therapy | Conjunctivitis, Allergic - diagnosis | Adolescent | Adult | Female | Conjunctivitis, Allergic - immunology | Desensitization, Immunologic - methods | Rhinitis | Immunotherapy | Pollen | Grasses | Medical treatment | Allergies | Colorectal cancer | Quality of life
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2. Full Text Long-term clinical efficacy in grass pollen–induced rhinoconjunctivitis after treatment with SQ-standardized grass allergy immunotherapy tablet
by Durham, Stephen R., MD and Emminger, Waltraud, MD and Kapp, Alexander, MD and Colombo, Giselda, MD and de Monchy, Jan G.R., MD and Rak, Sabina, MD and Scadding, Glenis K., MD, FRCP and Andersen, Jens S., PhD and Riis, Bente, PhD and Dahl, Ronald, MD and Sahlgrenska akademin and Göteborgs universitet and Institutionen för medicin, avdelningen för invärtesmedicin and Gothenburg University and Institute of Medicine, Department of Internal Medicine and Sahlgrenska Academy
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 1, pp. 131 - 138.e7
Background Sustained and disease-modifying effects of sublingual immunotherapy have never before been confirmed in a large-scale randomized, double-blind,... 
Allergy and Immunology | rhinoconjunctivitis | Phleum pratense | immunotherapy | Allergy immunotherapy tablet | placebo controlled | grass pollen | sublingual | disease modification | sustained efficacy | 6-YEAR FOLLOW-UP | CONTROLLED-TRIAL | SAFETY | PERFORMANCE | IMMUNOLOGY | HOUSE-DUST MITE | CHILDREN | RHINITIS | ALLERGY | BURDEN | SUBLINGUAL IMMUNOTHERAPY | IMMUNOLOGICAL CHANGES | Rhinitis, Allergic, Seasonal - physiopathology | Poaceae - immunology | Tablets - administration & dosage | Administration, Sublingual | Conjunctivitis, Allergic - physiopathology | Phleum - adverse effects | Double-Blind Method | Immunoglobulin G - blood | Humans | Treatment Outcome | Phleum - immunology | Pollen - immunology | Conjunctivitis, Allergic - therapy | Immunoglobulin E - blood | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - therapy | Time Factors | Quality of Life | Adult | Tablets - adverse effects | Conjunctivitis, Allergic - immunology | Desensitization, Immunologic - methods | Allergy | Medical colleges | Drug therapy | Allergic reaction | Immunotherapy | Disease | Pollen | Grasses | Seasons | Allergies | Quality of life | Asthma | Rhinitis | Tablets | methods | Immunoglobulin G | Phleum | Immunoglobulin E | Poaceae | Immunologi inom det medicinska området | Conjunctivitis | Seasonal | Allergic | administration & dosage | Immunologic | Sublingual | immunology | Immunology in the medical area | Administration | Desensitization | therapy | blood | physiopathology | adverse effects
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3. Full Text "Allergic mood" - Depressive and anxiety symptoms in patients with seasonal allergic rhinitis (SAR) and their association to inflammatory, endocrine, and allergic markers
by Trikojat, K and Luksch, H and Rosen-Wolff, A and Plessow, F and Schmitt, J and Buske-Kirschbaum, A
BRAIN BEHAVIOR AND IMMUNITY, ISSN 0889-1591, 10/2017, Volume 65, pp. 202 - 209
A growing number of studies show an association between seasonal allergic rhinitis (SAR) with depression and anxiety. The underlying mechanisms of a link... 
FUTURE-DIRECTIONS | CYTOKINES | Seasonal allergic rhinitis | Depression | Psychoneuroimmunology | NECROSIS-FACTOR-ALPHA | MAJOR DEPRESSION | IMMUNOLOGY | HAY-FEVER | INTERLEUKIN-6 | NEUROSCIENCES | IL-6 | Sleep | IMMUNE-SYSTEM | ASTHMA | Anxiety | STRESS | Tumor Necrosis Factor-alpha - metabolism | Rhinitis, Allergic, Seasonal - metabolism | Humans | Male | Interferon-gamma - metabolism | Affect | Rhinitis, Allergic, Seasonal - immunology | Depression - etiology | Inflammation - metabolism | Immunoglobulin E - immunology | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Adult | Female | Pollen | Interleukin-6 - metabolism | Hypersensitivity | Immunoglobulin E - metabolism | Inflammation - immunology | Biomarkers - blood | Allergens - metabolism | Anxiety - immunology | Rhinitis, Allergic, Seasonal - psychology | Anxiety - etiology | Depression - immunology | Care and treatment | Corticosteroids | Rhinitis | Interleukins | Depression, Mental | Immunoglobulin E
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4. Full Text Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study
by Jacobsen, L and Niggemann, B and Dreborg, S and Ferdousi, H. A and Halken, S and Host, A and Koivikko, A and Norberg, L. A and Valovirta, E and Wahn, U and Moller, C and PAT Investigator Grp and The PAT investigator group and Pediatrik and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Hälsouniversitetet
Allergy, ISSN 0105-4538, 08/2007, Volume 62, Issue 8, pp. 943 - 948
Background:  3-year subcutaneous specific immunotherapy (SIT) in children with seasonal allergic rhinoconjunctivitis reduced the risk of developing asthma... 
long-term effect | asthma | rhinitis | specific immunotherapy | prevention | long‐term effect | Prevention | Rhinitis | Long-term effect | Specific immunotherapy | Asthma | BRONCHIAL RESPONSIVENESS | INHALED CORTICOSTEROIDS | RISK | IMMUNOLOGY | CHILDHOOD | CHILDREN | ALLERGY | POLLEN IMMUNOTHERAPY | ALLERGIC RHINOCONJUNCTIVITIS | Allergens - therapeutic use | Antigens, Plant | Asthma - prevention & control | Follow-Up Studies | Humans | Male | Time | Rhinitis, Allergic, Seasonal - immunology | Allergens - immunology | Asthma - immunology | Adult | Female | Pollen | Odds Ratio | Plant Proteins - therapeutic use | Poaceae - immunology | Bronchial Provocation Tests - methods | Rhinitis, Allergic, Seasonal - complications | Risk Factors | Plant Proteins - immunology | Rhinitis, Allergic, Seasonal - prevention & control | Pain Measurement - methods | Asthma - complications | Betula - immunology | Adolescent | Skin Tests - methods | Longitudinal Studies | Desensitization, Immunologic - methods | Allergens | Immunotherapy | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICIN | MEDICINE
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5. Full Text From atopic dermatitis to asthma: the atopic march
by Spergel, Jonathan M., MD, PhD
Annals of Allergy, Asthma & Immunology, ISSN 1081-1206, 2010, Volume 105, Issue 2, pp. 99 - 106
Objective To examine the mechanisms whereby allergen exposure through the epidermis could initiate systemic allergy and predispose individuals to the... 
Allergy and Immunology | RUSSIAN KARELIA | MAJOR RISK-FACTOR | ALLERGY | FILAGGRIN | PHASE-III | INHALED CORTICOSTEROIDS | AIRWAY INFLAMMATION | FOLLOW-UP | OF-FUNCTION MUTATIONS | PEANUT ALLERGY | IMMUNOLOGY | YOUNG-CHILDREN | Rhinitis, Allergic, Seasonal - physiopathology | Dermatitis, Atopic - genetics | Dermatitis, Atopic - epidemiology | United States | Humans | Rhinitis, Allergic, Perennial - physiopathology | Rhinitis, Allergic, Perennial - epidemiology | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - epidemiology | Allergens - immunology | Asthma - immunology | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Asthma - epidemiology | Epidermis - metabolism | Genetic Predisposition to Disease | Rhinitis, Allergic, Perennial - genetics | Rhinitis, Allergic, Perennial - immunology | Rhinitis, Allergic, Seasonal - genetics | Asthma - physiopathology | Comorbidity | Dermatitis, Atopic - physiopathology | Mutation - genetics | Asthma - genetics | Disease Progression | Environmental Exposure - adverse effects | Epidermis - immunology | Age of Onset
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6. Full Text The effect of component-resolved diagnosis on specific immunotherapy prescription in children with hay fever
by Stringari, Giovanna, MD and Tripodi, Salvatore, MD and Caffarelli, Carlo, MD and Dondi, Arianna, MD and Asero, Riccardo, MD and Di Rienzo Businco, Andrea, MD and Bianchi, Annamaria, MD and Candelotti, Paolo, MD and Ricci, Giampaolo, MD and Bellini, Federica, MD and Maiello, Nunzia, MD and Miraglia del Giudice, Michele, MD and Frediani, Tullio, MD and Sodano, Simona, MD and Dello Iacono, Iride, MD and Macrì, Francesco, MD and Peparini, Ilaria, MD and Povesi Dascola, Carlotta, MD and Patria, Maria Francesca, MD and Varin, Elena, MD and Peroni, Diego, MD and Comberiati, Pasquale, MD and Chini, Loredana, MD and Moschese, Viviana, MD and Lucarelli, Sandra, MD and Bernardini, Roberto, MD and Pingitore, Giuseppe, MD and Pelosi, Umberto, MD, PhD and Tosca, Mariangela, MD and Cirisano, Anastasia, MD and Faggian, Diego, Biol Sci and Travaglini, Alessandro, MSc and Plebani, Mario, MD and Matricardi, Paolo Maria, MD and I-PAN and Italian Pediatric Allergy Network (I-PAN)
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 1, pp. 75 - 81.e2
Background Sensitization to profilins and other cross-reacting molecules might hinder proper specific immunotherapy (SIT) prescription in polysensitized... 
Allergy and Immunology | profilin | children | pollen | Allergic rhinitis | IgE | panallergens | component-resolved diagnosis | specific immunotherapy | MANAGEMENT | POLLEN ALLERGY | POLYSENSITIZED PATIENTS | SYMPTOMS | ALLERGEN-SPECIFIC IMMUNOTHERAPY | PREVALENCE | IMMUNOLOGY | GUIDE | RHINITIS | IMPACT | ALLERGY | ASTHMA | Gene Expression | Skin Tests | Humans | Profilins - immunology | Child, Preschool | Male | Pollen - immunology | Rhinitis, Allergic, Seasonal - diagnosis | Immunoglobulin E - blood | Rhinitis, Allergic, Seasonal - immunology | Cross Reactions | Rhinitis, Allergic, Seasonal - therapy | Allergens - immunology | Profilins - genetics | Adolescent | Allergens - chemistry | Female | Pollen - chemistry | Rhinitis, Allergic, Seasonal - pathology | Child | Plants - immunology | Desensitization, Immunologic - methods | Pediatric pharmacology | Medical colleges | Immunotherapy | Pediatrics | Pollen | Allergies | Asthma
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7. Full Text Acupuncture in patients with seasonal allergic rhinitis a randomized trial
by Brinkhaus, Benno and Ortiz, Miriam and Witt, Claudia M and Roll, Stephanie and Linde, Klaus and Pfab, Florian and Niggemann, Bodo and Hummelsberger, Josef and Treszl, András and Ring, Johannes and Zuberbier, Torsten and Wegscheider, Karl and Willich, Stefan N
Annals of Internal Medicine, ISSN 0003-4819, 02/2013, Volume 158, Issue 4, pp. 225 - 234
Background: Acupuncture is frequently used to treat seasonal allergic rhinitis (SAR) despite limited scientific evidence. Objective: To evaluate the effects of... 
CONTROLLED CLINICAL-TRIAL | MEDICINE, GENERAL & INTERNAL | EXPERIMENTALLY INDUCED ITCH | I HYPERSENSITIVITY ITCH | CROSSOVER TRIAL | ATOPIC ECZEMA | RHINOCONJUNCTIVITIS | QUALITY-OF-LIFE | ALTERNATIVE MEDICINE | QUESTIONNAIRE | COMPLEMENTARY | Humans | Rhinitis, Allergic, Seasonal - drug therapy | Male | Poaceae | Treatment Outcome | Acupuncture Therapy | Cetirizine - therapeutic use | Pollen - immunology | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - therapy | Immunoglobulin E - immunology | Histamine H1 Antagonists - therapeutic use | Quality of Life | Female | Surveys and Questionnaires | Betula | Antihistamines | Complications and side effects | Care and treatment | Dosage and administration | Acupuncture | Health aspects | Hay-fever | Histamine | Medical treatment | Allergies | Effectiveness studies
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8. Full Text Sublingual immunotherapy with once-daily grass allergen tablets: A randomized controlled trial in seasonal allergic rhinoconjunctivitis
by Durham, Stephen R and Yang, William H and Pedersen, Martin R and Johansen, Niels and Rak, Sabina
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2006, Volume 117, Issue 4, pp. 802 - 809
Specific immunotherapy is the only treatment modality that has the potential to alter the natural course of allergic diseases. Sublingual immunotherapy has... 
Specific immunotherapy | grass allergen tablets | sublingual immunotherapy | METAANALYSIS | EFFICACY | SAFETY | FOLLOW-UP | IMMUNOLOGY | HAY-FEVER | CHILDREN | RHINITIS | ALLERGY | POLLEN IMMUNOTHERAPY | ASTHMA | specific immunotherapy | Poaceae - immunology | Administration, Sublingual | Humans | Middle Aged | Male | Conjunctivitis, Allergic - therapy | Rhinitis, Allergic, Seasonal - immunology | Allergens - administration & dosage | Rhinitis, Allergic, Seasonal - therapy | Desensitization, Immunologic - adverse effects | Adolescent | Adult | Female | Aged | Pollen | Conjunctivitis, Allergic - immunology | Desensitization, Immunologic - methods | Allergy | Allergens | Allergic reaction | Immunotherapy | Allergies | Investigations | Quality of life | Asthma
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9. Full Text Results from the 5-year SQ grass sublingual immunotherapy tablet asthma prevention (GAP) trial in children with grass pollen allergy
by Valovirta, Erkka and Petersen, Thomas H and Petersen, Thomas Houmann and Piotrowska, Teresa and Laursen, Mette K and Andersen, Bjarne Dag and Andersen, Jens S and Sørensen, Helle F and Klink, Rabih and Varga, Eva-Maria and Huttegger, Isidor and Agertoft, Lone and Halken, Susanne and Jørgensen, Merete and Hansen, Kirsten Skamstrup and Hansen, Lars G and Cronjäger, Roswitha and Rubak, Sune and Csonka, Péter and Mickelsson, Ove and de Blic, Jacques and Thi, Nham Pham and Refabert, Luc and Pasquet, Christine and Broue-Chabbert, Anne and Juchet, Agnes and Lebeaupin, Bruno and Durand-Perdriel, François and Wessel, François and Payot, Francois and Girodet, Bruno and Houssel, Jean-Marc and Andre-Gomez, Sylvie-Anne and Riotte-Flandrois, Françoise and Basset, Dominique and Mounier, Dominique and Robberecht, Marie Noelle and Delbecque, Laure and Fauquert, Jean-Luc and Prud'Homme, Anne and Auffret, Annick and Luet-Gautier, Béatrice and Perello, Montserrat Agell and Bouillot, Fabrice and Bufe, Albrecht and von Berg, Andrea and Gappa, Monika and Vogelberg, Christian and Hamelmann, Eckhard and Schauer, Uwe and Stephan, Volker and Eberle, Peter and Bedikian, Raffi and Bosch, Peter and Christmann, J. Peter and Franke, Egbert and Dahlheim, Marcus and Kaiser, Friedrich and Knecht, Roland and Sandner, Bernard and Gronke, Christine and Köllges, Ralph and Franke-Beckmann, Eivy and Klimek, Ludger and Hoffmann, Matthias and Bretschneider, Ingrid and Herland Berstad, Aud Katrine and Kvenshagen, Bente and Øymar, Knut A and Kolsrud, Espen and Søyland, Anne and Dyczek, Andrzej and Bokiej, Juliusz and Hofman, Teresa and Springer, Ewa and Lisiecka, Maria and Madaj, Anna and Trębas-Pietraś, Ewa and Wytrychowski, Krzysztof and Żurowska-Gębala, Malgorzata Zurowska and Moszyńska, Danuta and Kwaśniewski, Artur and Ojeda, Pedro and Ibáñez, M and Cimarra, Mercedes and Infante, Sonsoles and Quirce, Santiago and González, Eloina and Vega, Arancha and Panizo, Carmen and Tabar, Ana Isabel and Vidal, Carmen and Gómez, Alicia Alonso and Parra, Beatriz Fernández and Winnergård, Inger and Kiotseridis, Hampus and Söderman, Päivi and Alm, Johan and Jönsson, Jan-Åke and Berner, Anders and ... and GAP Investigators and GAP investigators
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2018, Volume 141, Issue 2, pp. 529 - 538.e13
Allergy immunotherapy targets the immunological cause of allergic rhinoconjunctivitis and allergic asthma and has the potential to alter the natural course of... 
asthma symptoms | children | disease-modifying treatment | Allergy immunotherapy | long-term trial | PAT | FOLLOW-UP | RISK | IMMUNOLOGY | CHILDHOOD | RHINITIS | IMPACT | ALLERGY | RHINOCONJUNCTIVITIS | Double-Blind Method | Follow-Up Studies | Tablets | Humans | Child, Preschool | Conjunctivitis, Allergic - pathology | Male | Sublingual Immunotherapy | Conjunctivitis, Allergic - therapy | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - therapy | Asthma - immunology | Asthma - therapy | Female | Rhinitis, Allergic, Seasonal - pathology | Asthma - pathology | Child | Conjunctivitis, Allergic - immunology | Drugs | Pediatrics | Respiratory function | Medical services | Clinical trials | Immunoglobulin E | Risk | Family medical history | Prevention | Immunology | Immunotherapy | International conferences | Pollen | Children | Drug therapy | Rhinoconjunctivitis | Hypersensitivity | Oral administration | Pharmacology | Grasses | Allergies | Asthma | Studies | Lungs | Skin | Clinical medicine | Skin tests
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10. Full Text Food Allergy Among Children in the United States
by Branum, Amy M and Lukacs, Susan L
Pediatrics, ISSN 0031-4005, 12/2009, Volume 124, Issue 6, pp. 1549 - 1555
OBJECTIVES: The goals were to estimate the prevalence of food allergy and to describe trends in food allergy prevalence and health care use among US children.... 
Surveys | Food allergy | Food hypersensitivity | food hypersensitivity | EMERGENCY-DEPARTMENT VISITS | HOSPITAL ADMISSIONS | surveys | PEDIATRICS | PREVALENCE | food allergy | PEANUT | Dermatitis, Allergic Contact - immunology | Ambulatory Care - utilization | Humans | Child, Preschool | Infant | Male | Health Services - utilization | Immunoglobulin E - blood | Rhinitis, Allergic, Perennial - epidemiology | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - epidemiology | Utilization Review - statistics & numerical data | Food Hypersensitivity - immunology | Female | Emergency Service, Hospital - utilization | Referral and Consultation - utilization | Child | Rhinitis, Allergic, Perennial - immunology | Cross-Sectional Studies | Ambulatory Care Facilities - utilization | Food Hypersensitivity - epidemiology | Dermatitis, Allergic Contact - epidemiology | Health Surveys | Adolescent | Arachis - immunology | Demographic aspects | Forecasts and trends | Food allergies | Pediatrics | Immunoglobulins | Hospitalization | Nutrition | Childrens health
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11. Full Text Endotypes of pollen‐food syndrome in children with seasonal allergic rhinoconjunctivitis: a molecular classification
by Mastrorilli, C and Tripodi, S and Caffarelli, C and Perna, S and Di Rienzo‐Businco, A and Sfika, I and Asero, R and Dondi, A and Bianchi, A and Povesi Dascola, C and Ricci, G and Cipriani, F and Maiello, N and Miraglia Del Giudice, M and Frediani, T and Frediani, S and Macrì, F and Pistoletti, C and Dello Iacono, I and Patria, M. F and Varin, E and Peroni, D and Comberiati, P and Chini, L and Moschese, V and Lucarelli, S and Bernardini, R and Pingitore, G and Pelosi, U and Olcese, R and Moretti, M and Cirisano, A and Faggian, D and Travaglini, A and Plebani, M and Verga, M. C and Calvani, M and Giordani, P and Matricardi, P. M and Italian Pediat Allergy Network and Italian Pediatric Allergy Network (I-PAN) and the Italian Pediatric Allergy Network (I-PAN)
Allergy, ISSN 0105-4538, 08/2016, Volume 71, Issue 8, pp. 1181 - 1191
BackgroundPollen-food syndrome (PFS) is heterogeneous with regard to triggers, severity, natural history, comorbidities, and response to treatment. Our study... 
endotypes | pollen‐food syndrome | allergic rhinoconjunctivitis | children | molecules | oral allergy syndrome | panallergens | classification | cluster analysis | pollen-food syndrome | COMPONENT-RESOLVED DIAGNOSIS | PLANT-FOODS | IGE | ORAL ALLERGY | IMMUNOLOGY | HAY-FEVER | PEDIATRIC POPULATION | REACTIVITY PROFILES | CLINICAL-RELEVANCE | ALLERGY | RECOMBINANT ALLERGENS | PHLEUM-PRATENSE | Humans | Child, Preschool | Male | Pollen - immunology | Rhinitis, Allergic, Seasonal - diagnosis | Immunoglobulin E - blood | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - epidemiology | Food Hypersensitivity - immunology | Immunoglobulin E - immunology | Allergens - immunology | Female | Seasons | Child | Food - adverse effects | Skin Tests | Comorbidity | Risk Factors | Food Hypersensitivity - epidemiology | Syndrome | Conjunctivitis, Allergic - diagnosis | Conjunctivitis, Allergic - epidemiology | Adolescent | Age of Onset | Italy - epidemiology | Population Surveillance | Food Hypersensitivity - diagnosis | Cluster Analysis | Conjunctivitis, Allergic - immunology | Immunoglobulin E | Allergy | Conjunctivitis | Allergic reaction | Analysis | Food allergies | Pollen | Children & youth
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