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Materials Science and Engineering C, ISSN 0928-4931, 09/2017, Volume 78, pp. 443 - 451
A dual-layer TiO surface with hierarchical macro and mesoporous structure was prepared by a combinational approach of micro-arc oxidation followed by... 
Titanium | RhoA/ROCK | Macro/mesoporous TiO | Cell adhesion | Pyridines | Humans | Amides | Porosity | Cell Adhesion | Osteoblasts
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 01/2018, Volume 97, pp. 369 - 374
Infantile pneumonia is a common disease in children, which affects cardiopulmonary function and even threats to life. Therefore, overall analysis about the... 
Infantile pneumonia | RhoA/ROCK/NF-κB pathway | P300 | Lipopolysaccharide (LPS) | MEDICINE, RESEARCH & EXPERIMENTAL | COMMUNITY-ACQUIRED PNEUMONIA | ACTIVATION | MACROPHAGES | ACUTE LUNG INJURY | DISORDERS | CHILDREN | RhoA/ROCK/NF-kappa B pathway | GENE-EXPRESSION | LIPOPOLYSACCHARIDE | VERATRIC ACID | PHARMACOLOGY & PHARMACY | ACETYLTRANSFERASES
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 03/2019, Volume 10, Issue 18, pp. 1716 - 1728
The cholesterol-lowering statins have known anti-cancer effects, but the mechanisms and how to utilize statins in oncology have been unclear. We noted in the... 
Journal Article
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 12/2018, Volume 70, Issue 12, pp. 1713 - 1722
Objectives Total flavones of Rhododendron simsii Planch flower (TFR) are an effective part extracted from the flower. The present study was designed to... 
RhoA‐ROCK pathway | total flavones of Rhododendron simsii Planch flower | protective effect | ischaemia‐reperfusion injury | urotensin receptor | ischaemia-reperfusion injury | RhoA-ROCK pathway | CARDIAC TROPONIN | UROTENSIN II RECEPTOR | MYOCARDIAL-ISCHEMIA | PHARMACOLOGY & PHARMACY | BINDING | KINASES | Creatine Kinase, MB Form - drug effects | Plant Extracts - pharmacology | Protective Agents | Rats | Male | Flowers | L-Lactate Dehydrogenase - drug effects | Rats, Sprague-Dawley | Verapamil - pharmacology | rhoA GTP-Binding Protein - drug effects | Troponin I - drug effects | Dose-Response Relationship, Drug | Plant Extracts - administration & dosage | Animals | Flavones - administration & dosage | rho-Associated Kinases - drug effects | Female | Coronary Circulation - drug effects | Receptors, G-Protein-Coupled - drug effects | Rhododendron | Flavones - pharmacology | Myocardial Reperfusion Injury - prevention & control | Flavonoids | Flavones | Creatine kinase | Bioflavonoids | Creatine | Protein kinases | Reperfusion injury | Heart | Parameters | RhoA protein | Lactate dehydrogenase | Kinases | Coronary artery disease | L-Lactate dehydrogenase | Proteins | Troponin | Reperfusion | Troponin I | Ischemia | Perfusion | Protein kinase | Rodents | Calcium-binding protein | Myocardium | Rocks | Lactic acid | Inhibition
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2019, Volume 843, pp. 27 - 33
Improper cervical function may lead premature or late-term birth. The RhoA/Rho-kinase (ROCK) signalling pathway takes part in cellular functions including... 
Pregnancy | RhoA/ROCK pathway | Cervical ripening | Simvastatin | Fasudil | ACTIVATION | PHYSIOLOGY | PHOSPHORYLATION | INJURY | MATRIX METALLOPROTEINASES | OVEREXPRESSION | COLLAGEN-SYNTHESIS | PHARMACOLOGY & PHARMACY | MYOSIN PHOSPHATASE
Journal Article
ACS Applied Materials & Interfaces, ISSN 1944-8244, 09/2016, Volume 8, Issue 35, pp. 22884 - 22891
Journal Article
Experimental Neurology, ISSN 0014-4886, 10/2018, Volume 308, pp. 26 - 34
RhoA is a small GTPase that regulates many functions of mammalian cells via actin reorganization. Lots of studies uncovered that its activation acts as a major... 
ROCK | Differentiation | Schwann cell | JNK | RhoA | ACTIVATION | MYELINATION | REGENERATION | KINASE | DEDIFFERENTIATION | NEUROSCIENCES | NEGATIVE REGULATOR | SMALL GTPASE | AXON GROWTH-INHIBITION | RHOA/ROCK | SPINAL-CORD-INJURY | Muscle proteins | Cell differentiation | Tissue engineering | Cells
Journal Article
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 12, pp. 10375 - 10387
Carcinoma-associated fibroblasts (CAFs) can remodel the extracellular matrix to promote cancer cell invasion, but the paracrine signaling between CAFs and... 
Insulin-like growth factor-1 | Carcinoma-associated fibroblasts | Cancer cell scattering and invasion | Plasminogen activator inhibitor-1 | RhoA/ROCK signaling
Journal Article
RSC Advances, ISSN 2046-2069, 2017, Volume 7, Issue 14, pp. 8521 - 8532
A hierarchical macropore/nano implant surface has been considered as an effective approach to endow biomaterials with better osteogenic performance and... 
PROTEIN ADSORPTION | PHOSPHORYLATION | MICROTOPOGRAPHY | CHEMISTRY | RHOA/ROCK | OSTEOGENIC DIFFERENTIATION | TOPOGRAPHY | FOCAL ADHESION KINASE | SCALE | CHEMISTRY, MULTIDISCIPLINARY | MECHANOTRANSDUCTION
Journal Article
Biomaterials, ISSN 0142-9612, 2010, Volume 31, Issue 27, pp. 6952 - 6958
Abstract To maintain or enhance cell function by controlling its shape is an important consideration in scaffold design. Tenocyte is characterized by its... 
Advanced Basic Science | Dentistry | Tenomodulin | Tenocytes | LPA | RhoA/ROCK | Y27632 | Elongated morphology | MATERIALS SCIENCE, BIOMATERIALS | ROCK | ENGINEERED TENDON | ENGINEERING, BIOMEDICAL | ADHESION | SHAPE | ENDOTHELIAL-CELLS | RHO | ARTICULAR CHONDROCYTES | DIFFERENTIATION | EXPRESSION
Journal Article