X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5837) 5837
Publication (485) 485
Book Review (75) 75
Book Chapter (40) 40
Conference Proceeding (26) 26
Data Set (3) 3
Dissertation (2) 2
Magazine Article (1) 1
Newspaper Article (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (5323) 5323
animals (3056) 3056
humans (2380) 2380
rhodamines - metabolism (1282) 1282
rhodamines (1205) 1205
biochemistry & molecular biology (1061) 1061
rats (1024) 1024
rhodamines - chemistry (959) 959
mice (956) 956
fluorescence (930) 930
male (908) 908
fluorescent dyes (890) 890
rhodamine 123 (788) 788
p-glycoprotein (713) 713
pharmacology & pharmacy (711) 711
rhodamine (704) 704
female (611) 611
cell biology (607) 607
fluorescent dyes - metabolism (581) 581
cells, cultured (580) 580
cells (569) 569
cell line, tumor (522) 522
kinetics (518) 518
atp-binding cassette, sub-family b, member 1 - metabolism (517) 517
fluorescent dyes - chemistry (508) 508
expression (494) 494
microscopy, fluorescence (487) 487
cell line (485) 485
flow cytometry (462) 462
rhodamine 123 - metabolism (459) 459
analysis (445) 445
time factors (437) 437
proteins (411) 411
mitochondria - metabolism (403) 403
rhodamines - pharmacology (394) 394
chemistry, multidisciplinary (392) 392
in-vitro (390) 390
neurosciences (380) 380
apoptosis (377) 377
biophysics (363) 363
cancer (358) 358
mitochondria (358) 358
microscopy, confocal (357) 357
multidrug-resistance (331) 331
research (326) 326
hydrogen-ion concentration (325) 325
oncology (322) 322
dose-response relationship, drug (321) 321
multidrug resistance (319) 319
cell survival - drug effects (313) 313
article (293) 293
spectrometry, fluorescence (292) 292
nanoparticles (291) 291
rhodamines - pharmacokinetics (286) 286
tumor cells, cultured (285) 285
biological transport (283) 283
rats, sprague-dawley (271) 271
protein (269) 269
biochemical research methods (266) 266
transport (264) 264
in vitro techniques (263) 263
chemistry, analytical (262) 262
permeability (262) 262
in-vivo (259) 259
rats, wistar (254) 254
living cells (243) 243
inhibition (240) 240
cell membrane - metabolism (234) 234
actins - metabolism (227) 227
drugs (224) 224
drug resistance, multiple (223) 223
mitochondria - drug effects (222) 222
antineoplastic agents - pharmacology (218) 218
calcium - metabolism (218) 218
multidisciplinary sciences (218) 218
protein binding (218) 218
oxidative stress (215) 215
binding (211) 211
atp-binding cassette, sub-family b, member 1 - antagonists & inhibitors (207) 207
rhodamine 123 - pharmacokinetics (206) 206
physiology (204) 204
reactive oxygen species - metabolism (203) 203
physiological aspects (202) 202
gene expression (200) 200
verapamil - pharmacology (198) 198
drug resistance (196) 196
atp-binding cassette, sub-family b, member 1 - genetics (195) 195
chemistry, medicinal (193) 193
immunohistochemistry (191) 191
activation (188) 188
drug delivery systems (184) 184
hela cells (182) 182
metabolism (182) 182
biochemistry (181) 181
doxorubicin - pharmacology (179) 179
rhodamin (178) 178
dyes (177) 177
rabbits (177) 177
cytotoxicity (174) 174
molecular sequence data (174) 174
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (5761) 5761
Chinese (34) 34
Russian (24) 24
Japanese (9) 9
Spanish (5) 5
French (4) 4
German (3) 3
Czech (1) 1
Korean (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2003, Volume 112, Issue 12, pp. 1831 - 1842
Failure to secrete adequate amounts of insulin in response to increasing concentrations of glucose is an important feature of type 2 diabetes. The mechanism... 
MEDICINE, RESEARCH & EXPERIMENTAL | CONCANAVALIN-A | OXYGEN SPECIES PRODUCTION | OXIDATIVE STRESS | CHRONIC EXPOSURE | FREE FATTY-ACIDS | OB-OB MICE | INSULIN-SECRETION | GLUTATHIONE-PEROXIDASE | ENERGY-METABOLISM | GLUCOSE TOXICITY
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 2/2007, Volume 296, Issue 1, pp. 85 - 95
Many studies have been performed with the aim of developing effective resistance modulators to overcome the multidrug resistance (MDR) of human cancers. Potent... 
Life Sciences | Biochemistry, general | P-glycoprotein | tetrahydrocurcumin | multidrug resistance | ATP hydrolysis | drug transport | Oncology | Medical Biochemistry | Cardiology | chemosensitivity | ABC transporter | Drug transport | Multidrug resistance | Chemosensitivity | Tetrahydrocurcumin | MECHANISM | INVOLVEMENT | CHEMOPREVENTIVE AGENT CURCUMIN | CATALYTIC TRANSITION-STATE | CELL BIOLOGY | MICROORGANISMS | BREAST-CANCER CELLS | IN-VITRO | INHIBITION | PROTECTIVE ROLE | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Vinblastine - metabolism | Curcumin - analogs & derivatives | Fluorides - metabolism | Curcumin - chemistry | Fluoresceins - metabolism | Humans | Chlorophyll - analogs & derivatives | Fluorescent Dyes - metabolism | Drug Resistance, Neoplasm | Curcumin - metabolism | Neoplasm Proteins - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 | Organic Anion Transporters - metabolism | Antineoplastic Agents - metabolism | Beryllium - metabolism | Adenosine Triphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Molecular Structure | Drug Resistance, Multiple - physiology | Mitoxantrone - metabolism | Etoposide - metabolism | Chlorophyll - metabolism | Antineoplastic Agents - chemistry | Rhodamine 123 - metabolism | Cell Line, Tumor | ATP Binding Cassette Transporter, Sub-Family B | Multidrug Resistance-Associated Proteins - metabolism | Proteins | Medical research | Binding sites | Index Medicus
Journal Article
Neurochemistry International, ISSN 0197-0186, 2009, Volume 54, Issue 3, pp. 253 - 263
Blood–brain barrier (BBB) characteristics are induced and maintained by cross-talk between brain microvessel endothelial cells and neighbouring elements of the... 
Astrocytes | Pericytes | In vitro BBB model (rat) | Tight junction | Transendothelial electrical resistance | Co-culture | P-Glycoprotein | Drug permeability | Blood–brain barrier | Brain endothelial cells | Blood-brain barrier | DRUG | PERMEABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANGIOPOIETIN-1 | INDUCTION | GLIAL-CELLS | NEUROSCIENCES | MESSENGER-RNA | IN-VITRO MODEL | CULTURES | EXPRESSION | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Pericytes - ultrastructure | Phosphoproteins - metabolism | Blood-Brain Barrier - ultrastructure | Occludin | Microcirculation - physiology | Endothelial Cells - ultrastructure | Membrane Proteins - metabolism | Capillaries - metabolism | Rhodamine 123 - pharmacokinetics | Tight Junctions - metabolism | Microscopy, Electron, Transmission | Capillaries - ultrastructure | Endothelial Cells - metabolism | Pericytes - metabolism | Cells, Cultured | Rats | Claudin-5 | Cerebral Arteries - ultrastructure | Membrane Potentials - physiology | Blood-Brain Barrier - metabolism | Astrocytes - ultrastructure | Tight Junctions - ultrastructure | Animals | Carrier Proteins - metabolism | Zonula Occludens-1 Protein | Cell Membrane Permeability - physiology | Cerebral Arteries - metabolism | Models, Biological | Cell Membrane Permeability - drug effects | ATP Binding Cassette Transporter, Sub-Family B - metabolism | Astrocytes - metabolism | Proteins | Drug resistance in microorganisms | Brain | Fluorescein | Physiological aspects | Glucose | Universities and colleges | Permeability | Dextrose | Endothelium | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0152105 - e0152105
The endothelial cells that form capillaries in the brain are highly specialized, with tight junctions that minimize paracellular transport and an array of... 
PLURIPOTENT STEM-CELLS | DERIVATION | CLAUDIN | PERMEABILITY | TRANSPORTERS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | MODEL | TIGHT JUNCTION | EXPRESSION | ADVANCE TRANSLATIONAL RESEARCH | Tight Junctions - metabolism | Cell Line | Cadherins - metabolism | Induced Pluripotent Stem Cells - physiology | Endothelial Cells - metabolism | Humans | Claudin-5 - metabolism | Brain - physiology | Occludin - metabolism | Antigens, CD - metabolism | Blood-Brain Barrier - metabolism | Brain - metabolism | Capillaries - physiology | Rhodamine 123 - metabolism | Phenotype | Tight Junctions - physiology | Up-Regulation - physiology | Blood-Brain Barrier - physiology | Biological Transport - physiology | Zonula Occludens-1 Protein - metabolism | Capillaries - metabolism | Endothelial Cells - physiology | Induced Pluripotent Stem Cells - metabolism | Drugs | Nervous system diseases | Drug delivery systems | Blood-brain barrier | Physiological aspects | Genetic aspects | Research | Drug therapy | Vehicles | Rhodamine | Central nervous system | Derivation | Materials science | Drug delivery | Drug development | Proteins | Engineering | Rodents | Fibroblasts | Capillaries | Tacrine | Elongation | Efflux | Tight junctions | Blood vessels | Central nervous system diseases | Permeability | Cadherin | Zonula occludens-1 protein | Endothelial cells | Brain research | Cell lines | Stem cells | Microvasculature | Electrical junctions | Retinoic acid | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e91308 - e91308
Background/Aims: An increase of ethanol metabolism and hepatic mitochondrial respiration occurs in vivo after a single binge of alcohol. Here, our aim was to... 
OXIDATIVE STRESS | REACTIVE OXYGEN | SWIFT INCREASE | PERMEABILITY TRANSITION INHIBITOR | ACETALDEHYDE ADDUCTS | MULTIDISCIPLINARY SCIENCES | ALCOHOLIC LIVER-DISEASE | PERFUSED-RAT-LIVER | N-METHYL-4-ISOLEUCINE CYCLOSPORINE | STIMULATES GLYCOGENOLYSIS | INDUCED FAT ACCUMULATION | Alcohol Dehydrogenase - metabolism | Ethanol - metabolism | Fatty Liver - metabolism | Oxidative Stress | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Mitochondria, Liver - metabolism | Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | Hepatocytes - metabolism | Permeability | Hypoxia - metabolism | Mice, Knockout | Dose-Response Relationship, Drug | Mitochondria, Liver - drug effects | Ethanol - pharmacology | Animals | Liver - drug effects | Cation Transport Proteins - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Adenosine Triphosphate - metabolism | Cation Transport Proteins - genetics | Mice | Intracellular Membranes - metabolism | Alcohol, Denatured | Pyridine | Cell death | Cytochrome P-450 | Physiological aspects | Alcohol | Nucleotides | Acetaldehyde | Cytochrome | Rhodamine | Polarization | Phosphorylation | Dehydrogenases | Liver | Fluorescence | Propidium iodide | Activation | Alcohol dehydrogenase | Confocal | Kinases | Dehydrogenase | Aldehyde dehydrogenase | Depolarization | Mitochondria | Fatty liver | Metabolites | Rodents | Gastroenterology | Pyridine nucleotides | Calcein | Pyridines | Liver diseases | Ethanol | Iodides | Histology | Metabolism | Steatosis | DNA nucleotidylexotransferase | NAD | Microscopy | Hepatocytes | In vivo methods and tests | Electron transport | Respiration | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 49, pp. 6252 - 6255
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 12/2013, Volume 1833, Issue 12, pp. 2922 - 2932
Chronic hyperglycaemia during diabetes leads to non-enzymatic glycation of proteins to form advanced glycation end products (AGEs) that contribute to... 
TGF-β | Nephropathy | Diabetes | Na+K+ATPase | Glycation | Macropinocytosis | ATPase | ALBUMIN-GOLD COMPLEXES | ADVANCED GLYCOSYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Na(+)K(+)ATPase | DIABETIC-NEPHROPATHY | NADPH OXIDASE ACTIVATION | MESENCHYMAL TRANSITION | PLASMA-MEMBRANE | CELL BIOLOGY | TGF-beta | RECEPTOR-MEDIATED ENDOCYTOSIS | GROWTH-FACTOR | RAC1 | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | Transforming Growth Factor beta1 - metabolism | Actins - metabolism | Fluorescein-5-isothiocyanate - metabolism | Rhodamines - metabolism | LLC-PK1 Cells | Phosphatidylinositol 4,5-Diphosphate - metabolism | Polymerization - drug effects | Pinocytosis - drug effects | Swine | Cytoskeletal Proteins - metabolism | ADP-Ribosylation Factors - metabolism | Epithelial Cells - cytology | Dextrans - metabolism | Kidney Tubules, Proximal - cytology | Cell Surface Extensions - metabolism | Fluorescein-5-isothiocyanate - analogs & derivatives | Serum Albumin, Bovine - metabolism | Down-Regulation - drug effects | p21-Activated Kinases - metabolism | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Phosphotransferases (Alcohol Group Acceptor) | Cell Surface Extensions - drug effects | Glycation End Products, Advanced - metabolism | Epithelial Cells - enzymology | rac1 GTP-Binding Protein - metabolism | RNA, Small Interfering - metabolism | Dextran | Bone morphogenetic proteins | Muscle proteins | Transforming growth factors | Proteins | Actin | Diabetic nephropathies | Adenosine triphosphatase
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9431 - 9436
Growing knowledge of the key molecular components involved in biological processes such as endocytosis, exocytosis, and motility has enabled direct testing of... 
Microscopy | Fluorescence | Transmembrane proteins | Lipids | Cell membranes | Chemical composition | Inkjet printers | P branes | Unilamellar liposomes | Membrane proteins | Transmembrane protein | Lipid bilayer | Synthetic biology | Microfluidic jetting | SNARE | transmembrane protein | FUSION | MULTIDISCIPLINARY SCIENCES | DROPLET INTERFACE BILAYERS | microfluidic jetting | PHOSPHOLIPID-MEMBRANES | PRINCIPLES | synthetic biology | UNILAMELLAR VESICLES | SURFACE | lipid bilayer | PROTEINS | RECONSTITUTION | Models, Chemical | R-SNARE Proteins - metabolism | Unilamellar Liposomes - chemistry | Green Fluorescent Proteins - genetics | Phosphatidylcholines - metabolism | Rhodamines - metabolism | Membrane Lipids - chemistry | Qa-SNARE Proteins - chemistry | Phosphatidylinositol 4,5-Diphosphate - metabolism | SNARE Proteins - chemistry | Biological Transport | Membrane Proteins - metabolism | Rhodamines - chemistry | Green Fluorescent Proteins - chemistry | Phosphatidylinositol 4,5-Diphosphate - chemistry | Green Fluorescent Proteins - metabolism | R-SNARE Proteins - genetics | Models, Molecular | Rats | Phosphatidylcholines - chemistry | R-SNARE Proteins - chemistry | Unilamellar Liposomes - metabolism | Microscopy, Confocal | Animals | Membrane Proteins - chemistry | Qa-SNARE Proteins - metabolism | Membrane Lipids - metabolism | Protein Binding | Kinetics | Porosity | Microfluidics - methods | SNARE Proteins - metabolism | Proteins | Cellular biology | Biochemistry | Models | Molecular biology | Index Medicus | Biological Sciences
Journal Article