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Nature Cell Biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1202 - 1213
Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch... 
LYMPHATIC ENDOTHELIUM | KINASE-ACTIVITY | VASCULAR NETWORK FORMATION | ENDOTHELIAL-GROWTH-FACTOR | FACTOR-C | MOUSE EMBRYOS | EXTRACELLULAR-MATRIX | MONOCLONAL-ANTIBODY | TUMOR ANGIOGENESIS | FACTOR RECEPTOR-3 | CELL BIOLOGY | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, Notch - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Receptors, Notch - antagonists & inhibitors | Transfection | RNA Interference | Time Factors | Forkhead Transcription Factors - metabolism | Vascular Endothelial Growth Factor D - genetics | Phosphatidylinositol 3-Kinase - metabolism | Vascular Endothelial Growth Factor Receptor-3 - deficiency | Transduction, Genetic | Retinal Vessels - metabolism | Endothelial Cells - metabolism | Rhombencephalon - blood supply | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Forkhead Transcription Factors - genetics | Vascular Endothelial Growth Factor C - genetics | Mice, Knockout | Antibodies - pharmacology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Vascular Endothelial Growth Factor C - metabolism | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Vascular Endothelial Growth Factor B - genetics | Mice | Neovascularization, Pathologic - metabolism | Protein Kinase Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-3 - genetics | Endothelial Cells - drug effects | Physiological aspects | Blood vessels | Cellular signal transduction | Growth factor receptors | Research | Vascular endothelial growth factor | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
PLoS Biology, ISSN 1545-7885, 2006, Volume 4, Issue 8, pp. 1438 - 1452
The link between extrinsic signaling, progenitor cell specification and neuronal subtype identity is central to the developmental organization of the... 
ANTERIOR NEUROECTODERM | RETINOIC ACID SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | SPINAL-CORD | CHICK-EMBRYO | T-BOX GENE | DISTINCT ROLES | POSITIONAL IDENTITY | INDUCTIVE SIGNALS | PARAXIAL MESODERM | MOUSE EMBRYO | Spinal Cord - metabolism | Homeodomain Proteins - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Wnt Proteins - metabolism | Central Nervous System - embryology | Rhombencephalon - cytology | Fibroblast Growth Factors - metabolism | Wnt Proteins - genetics | Tretinoin - metabolism | Gene Expression Regulation, Developmental | Motor Neurons - cytology | Spinal Cord - cytology | Genes, Homeobox | Rhombencephalon - embryology | Avian Proteins - metabolism | Signal Transduction | Chick Embryo | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | T-Box Domain Proteins - metabolism | Motor Neurons - metabolism | Spinal Cord - embryology | Animals | Rhombencephalon - metabolism | Avian Proteins - genetics | Development | Neuroscience | Chicken | Cell Biology | Basic Medicine | Gene Expression Regulation; Developmental | T-Box Domain Proteins/genetics/metabolism | Medical and Health Sciences | Medicin och hälsovetenskap | Central Nervous System/embryology | Cell and Molecular Biology | Spinal Cord/cytology/embryology/metabolism | Medicinska och farmaceutiska grundvetenskaper | Fibroblast Growth Factors/metabolism | Motor Neurons/cytology/metabolism | Stem Cells/cytology/metabolism | Wnt Proteins/genetics/metabolism | Avian Proteins/genetics/metabolism | Cell- och molekylärbiologi | Rhombencephalon/cytology/embryology/metabolism | Genes; Homeobox | Homeodomain Proteins/genetics/metabolism | Tretinoin/metabolism | Neurons | Spinal cord | Rodents
Journal Article
Cell, ISSN 0092-8674, 2002, Volume 109, Issue 1, pp. 61 - 73
OLIG1 and OLIG2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the pMN domain of the spinal cord, which sequentially generates... 
VENTRAL NEURAL-TUBE | MOTOR-NEURONS | PROGENITOR CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINAL-CORD OLIGODENDROCYTES | CENTRAL-NERVOUS-SYSTEM | LIM HOMEOBOX GENES | ACHAETE-SCUTE | MAMMALIAN-CELLS | EXPRESSION | LINEAGE | CELL BIOLOGY | Oligodendroglia - metabolism | Spinal Cord - metabolism | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | Transcription Factors - deficiency | Male | Neurons - cytology | Stem Cells - cytology | Stem Cells - metabolism | Rhombencephalon - cytology | Mutation - physiology | Neuroglia - cytology | Motor Neurons - cytology | Female | Interneurons - cytology | Neurons - metabolism | Oligodendroglia - cytology | Spinal Cord - cytology | Cell Differentiation - physiology | Rhombencephalon - embryology | Basic Helix-Loop-Helix Transcription Factors | DNA-Binding Proteins | Astrocytes - cytology | Oligodendrocyte Transcription Factor 2 | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Cell Lineage - physiology | Mice, Knockout | Motor Neurons - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Spinal Cord - embryology | Helix-Loop-Helix Motifs - genetics | Animals | Interneurons - metabolism | Rhombencephalon - metabolism | Neuroglia - metabolism | Mice | Astrocytes - metabolism | Cell research | Neurons | Analysis | Neuroglia | Physiological aspects | Genetic aspects | Genetic transcription | Helium
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 48, Issue 6, pp. 933 - 947
The lower rhombic lip (LRL) is a germinal zone in the dorsal hindbrain productive of tangentially migrating neurons, streaming extramurally (mossy fiber... 
ROOF PLATE | GENE | MOUSE | NEURAL-TUBE | MEDULLA-OBLONGATA | FLP-RECOMBINASE | CNS | NEURONAL FATES | MATH1 EXPRESSION | NEUROSCIENCES | DORSAL SPINAL-CORD | Paired Box Transcription Factors - genetics | Wnt1 Protein - genetics | Homeodomain Proteins - metabolism | Choroid Plexus - metabolism | Gene Expression Regulation, Developmental - genetics | Choroid Plexus - embryology | Stem Cells - cytology | Wnt1 Protein - metabolism | Stem Cells - metabolism | Cell Movement - genetics | Cerebellum - embryology | Olivary Nucleus - cytology | Rhombencephalon - cytology | Cell Differentiation - genetics | Bone Morphogenetic Proteins - metabolism | Choroid Plexus - cytology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Afferent Pathways - embryology | Growth Differentiation Factors | Eye Proteins - genetics | Bone Morphogenetic Proteins - genetics | Repressor Proteins - metabolism | Rhombencephalon - embryology | Afferent Pathways - metabolism | Olivary Nucleus - embryology | Nerve Fibers - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Cerebellum - metabolism | Repressor Proteins - genetics | Mice, Transgenic | PAX6 Transcription Factor | Afferent Pathways - cytology | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Olivary Nucleus - metabolism | Eye Proteins - metabolism | Cerebellum - cytology | Rhombencephalon - metabolism | LIM-Homeodomain Proteins | Mice | Nerve Fibers - ultrastructure | Transcription Factors | Body Patterning - genetics | Paired Box Transcription Factors - metabolism | Brain | Neurons | Derivatives | Microscopy | Rodents | Climbing
Journal Article
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 2016, Volume 311, Issue 6, pp. E939 - E948
Previous studies have shown that very lowdose infusions of leptin into the third or the fourth ventricle alone have little effect on energy balance, but... 
Energy expenditure | Rats | Food intake | Body composition | CHOLECYSTOKININ | PHYSIOLOGY | PHOSPHORYLATION | FOOD-INTAKE | energy expenditure | BODY-WEIGHT | body composition | HINDBRAIN | NUCLEUS | IN-VIVO | ENDOCRINOLOGY & METABOLISM | NEURONS | rats | FAT DEPOTS | food intake | Phosphoproteins - drug effects | Phosphatidylinositol 3-Kinase - drug effects | Male | Mitogen-Activated Protein Kinase 1 - drug effects | Phosphoproteins - metabolism | Rhombencephalon - drug effects | Phosphatidylinositol 3-Kinases | Dose-Response Relationship, Drug | Mitogen-Activated Protein Kinase 3 - drug effects | Liver - drug effects | Fourth Ventricle | Leptin - pharmacology | Hypothalamus - drug effects | Phosphatidylinositol 3-Kinase - metabolism | STAT3 Transcription Factor - metabolism | Uncoupling Protein 1 - drug effects | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - drug effects | Uncoupling Protein 1 - metabolism | Liver - metabolism | Rats, Sprague-Dawley | Blotting, Western | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Animals | Hypothalamus - metabolism | Mitogen-Activated Protein Kinase 3 - metabolism | STAT3 Transcription Factor - drug effects | Suppressor of Cytokine Signaling 3 Protein - drug effects | Rhombencephalon - metabolism | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Infusions, Intraventricular | Suppressor of Cytokine Signaling 3 Protein - metabolism | Energy Metabolism - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Cellular signal transduction | Genetic aspects | Genetic transcription | Health aspects | Leptin
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2014, Volume 184, Issue 2, pp. 382 - 396
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2012, Volume 32, Issue 38, pp. 13292 - 13308
MicroRNAs have emerged as key posttranscriptional regulators of gene expression during vertebrate development. We show that the miR-200 family plays a crucial... 
RNA INTERFERENCE | MOUSE-BRAIN | EMBRYONIC STEM-CELLS | GENE-EXPRESSION | CEREBELLUM DEVELOPMENT | III ENZYME DICER | DOPAMINERGIC-NEURONS | MAMMALIAN-CELLS | MIDBRAIN | NEUROSCIENCES | ISTHMIC ORGANIZER | Cell Cycle - genetics | Mesencephalon - cytology | Age Factors | Embryo, Mammalian | Cell Count | Homeodomain Proteins - metabolism | Humans | Cercopithecus aethiops | Gene Expression Regulation, Developmental - genetics | Male | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | SOXB1 Transcription Factors - metabolism | Rhombencephalon - cytology | Cell Differentiation - genetics | Transfection | Cell Death - genetics | SOXB1 Transcription Factors - genetics | Female | DEAD-box RNA Helicases - metabolism | Cell Differentiation - physiology | Gene Expression Regulation, Developmental - physiology | Ribonuclease III - genetics | Ribonuclease III - metabolism | Mice, Inbred C57BL | Cells, Cultured | Neural Stem Cells - physiology | E2F3 Transcription Factor - genetics | Mice, Transgenic | Signal Transduction - genetics | Transcription Factor Brn-3A - metabolism | Mutation - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | DEAD-box RNA Helicases - genetics | Animals | Deoxyuridine - analogs & derivatives | Deoxyuridine - metabolism | Models, Biological | Serotonin - metabolism | E2F3 Transcription Factor - metabolism | Cell Cycle - physiology | Mice | MicroRNAs - genetics
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 11/2004, Volume 480, Issue 1, pp. 1 - 18
Journal Article
Science, ISSN 0036-8075, 11/2010, Volume 330, Issue 6006, pp. 985 - 989
The orphan G protein-coupled receptor (GPCR) GPR124/tumor endothelial marker 5 is highly expressed in central nervous system (CNS) endothelium. Here, we show... 
Vascular malformations | Angiogenesis | Receptors | Sprouts | REPORTS | Central nervous system | Forebrain | Telencephalon | Embryos | Endothelial cells | Endothelium | INACTIVATION | LETHALITY | GENE | ENDOTHELIUM | HEMORRHAGE | MULTIDISCIPLINARY SCIENCES | NEUROGENESIS | CENTRAL-NERVOUS-SYSTEM | MICE | BLOOD-BRAIN-BARRIER | ALPHA-V INTEGRINS | Blood Vessels - abnormalities | Receptors, G-Protein-Coupled - metabolism | Mesencephalon - metabolism | Glucose Transporter Type 1 - metabolism | Gene Deletion | Neural Tube - metabolism | Prosencephalon - blood supply | Prosencephalon - metabolism | Endothelial Cells - physiology | Rhombencephalon - embryology | Endothelium, Vascular - embryology | Telencephalon - metabolism | Rhombencephalon - blood supply | Mice, Transgenic | Mesencephalon - blood supply | Telencephalon - embryology | Embryonic Development | Blood-Brain Barrier - metabolism | Mice, Knockout | Neural Tube - blood supply | Telencephalon - blood supply | Animals | Mesencephalon - embryology | Endothelium, Vascular - metabolism | Rhombencephalon - metabolism | Mice | Receptors, G-Protein-Coupled - genetics | Neural Tube - embryology | Prosencephalon - embryology | Neovascularization, Physiologic | Cell Movement | Physiological aspects | Neovascularization | G proteins | Properties | Membrane proteins | Proteins | Nervous system | Brain research | Veins & arteries | Tropism | Control | Migration | Markers | Adhesion
Journal Article
Journal Article