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PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 9, p. e0223008
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 8, p. e71006
Journal Article
Proteomics (Weinheim), ISSN 1615-9853, 05/2014, Volume 14, Issue 10, pp. 1174 - 1184
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 0028-0836, 2018, Volume 559, Issue 7713, pp. 285 - 289
The observation that BRCA1-and BRCA2-deficient cells are sensitive to inhibitors of poly(ADP-ribose) polymerase (PARP) has spurred the development of cancer... 
RNASE H2 | CELLS | REPLICATION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | DNA-DAMAGE | ANTIANDROGEN RESISTANCE | LINEAGE PLASTICITY | GENES | TRANSCRIPTION | TOPOISOMERASE-I | Humans | Genome - genetics | Male | Synthetic Lethal Mutations | DNA Repair - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Ribonucleotides - genetics | Neoplasms - genetics | Poly (ADP-Ribose) Polymerase-1 - deficiency | Female | Genes, BRCA1 | BRCA1 Protein - deficiency | Prostatic Neoplasms - drug therapy | Ribonuclease H - genetics | DNA Damage - drug effects | Cell Line | Prostatic Neoplasms - pathology | DNA Topoisomerases, Type I - metabolism | Ribonuclease H - deficiency | Neoplasms - enzymology | DNA Replication | Poly (ADP-Ribose) Polymerase-1 - metabolism | Piperazines - pharmacology | Gene Editing | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - enzymology | Animals | CRISPR-Cas Systems | Prostatic Neoplasms - enzymology | Mice | HeLa Cells | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Neoplasms - pathology | Poly (ADP-Ribose) Polymerase-1 - genetics | Ribonuclease H - metabolism | DNA polymerases | Physiological aspects | Ribonucleotides | Genetic aspects | Toxicity | Leukemia | Genomics | Homologous recombination | Genes | DNA damage | Poly(ADP-ribose) | Cytotoxicity | Homology | Genomes | Kinases | Metastases | Ribonuclease H2 | Proteins | Dwarfism | Genotype & phenotype | Clonal deletion | Ribose | Cell cycle | Inhibition | Lesions | Repair | Deoxyribonucleic acid--DNA | Adducts | BRCA2 protein | CRISPR | Enzymes | Chronic lymphatic leukemia | BRCA1 protein | Anemia | Hypersensitivity | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Breast cancer | Screens | Substrates | DNA biosynthesis | Poly(ADP-ribose) Polymerase 1 | Trapping | Inhibitors | Mutation | DNA adducts | Prostate cancer | Prostate | Cancer
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