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Nature, ISSN 0028-0836, 10/2010, Volume 467, Issue 7318, pp. 986 - 990
Aberrant expression of microRNAs (miRNAs) and the enzymes that control their processing have been reported in multiple biological processes including primary... 
MUTANT | LI-FRAUMENI-SYNDROME | MULTIDISCIPLINARY SCIENCES | P63 EXPRESSION | MICE | CANCER | P73 | CARCINOMA | PROGRESSION | P53 | FAMILY | Genomic Instability | Endoribonucleases - genetics | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Male | MicroRNAs - metabolism | Phosphoproteins - metabolism | Promoter Regions, Genetic - genetics | DEAD-box RNA Helicases - biosynthesis | Neoplasms - genetics | Cellular Senescence | Tumor Suppressor Proteins - deficiency | DEAD-box RNA Helicases - deficiency | Genes, Tumor Suppressor - physiology | Tumor Suppressor Proteins - genetics | Trans-Activators - genetics | Female | DEAD-box RNA Helicases - metabolism | Cell Line | Neoplasms - secretion | Tumor Suppressor Proteins - metabolism | Ribonuclease III - genetics | Ribonuclease III - metabolism | Endoribonucleases - metabolism | Mice, Inbred C57BL | MicroRNAs - biosynthesis | Phosphoproteins - genetics | Ribonuclease III - biosynthesis | Ribonuclease III - deficiency | DEAD-box RNA Helicases - genetics | Neoplasm Metastasis - genetics | Animals | Trans-Activators - deficiency | Phosphoproteins - deficiency | Cell Line, Tumor | Trans-Activators - metabolism | Mice | MicroRNAs - genetics | Transcription Factors | Neoplasms - pathology | Care and treatment | MicroRNA | Tumor suppressor genes | Genetic aspects | Metastasis | Research | Health aspects | Risk factors | Genotype & phenotype | Medical research | Binding sites | Tumors | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue 7377, pp. 391 - 395
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7418, pp. 112 - 115
Journal Article
Science, ISSN 0036-8075, 10/2009, Volume 326, Issue 5952, pp. 544 - 550
RNA interference (RNAi), a gene-silencing pathway triggered by double-stranded RNA, is conserved in diverse eukaryotic species but has been lost in the model... 
Genetic transposition | Double stranded RNA | Messenger RNA | Transposons | RNA | Genomics | Small interfering RNA | Genetic loci | Research Articles | Open reading frames | Saccharomycetales | ELEMENTS | EVOLUTION | INITIATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | RESOLUTION | PROTEINS | SACCHAROMYCES-CEREVISIAE | GENOME | RIBONUCLEASE | SCHIZOSACCHAROMYCES-POMBE | RNA, Small Interfering - genetics | Saccharomyces cerevisiae - genetics | Open Reading Frames | Gene Expression Profiling | Genetic Loci | RNA, Messenger - metabolism | Saccharomyces - genetics | Saccharomyces cerevisiae - metabolism | RNA Interference | Saccharomyces - metabolism | Genes, Fungal | Transcription, Genetic | RNA, Double-Stranded - metabolism | RNA, Fungal - genetics | Transformation, Genetic | Ribonuclease III - genetics | Ribonuclease III - metabolism | Retroelements | RNA, Messenger - genetics | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | RNA, Fungal - metabolism | Saccharomycetales - genetics | Sequence Analysis, RNA | RNA, Double-Stranded - genetics | Saccharomyces cerevisiae Proteins - metabolism | Repetitive Sequences, Nucleic Acid | Mutation | Saccharomycetales - metabolism | Fungal Proteins - metabolism | RNA, Small Interfering - metabolism | Physiological aspects | Brewer's yeast | Genetic aspects | Proteins | Signal transduction | Yeast | Cellular biology | Ribonucleic acid--RNA | Gene expression | Dicer protein | Index Medicus
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 65, Issue 5, pp. 597 - 611
To investigate the role of microRNAs in regulating oligodendrocyte (OL) differentiation and myelination, we utilized transgenic mice in which microRNA... 
DEVBIO | MOLNEURO | TRANSCRIPTION FACTORS | NERVOUS-SYSTEM | GLIAL PROGENITOR-CELL | PROTEIN | CYCLE EXIT | NEURONS | GROWTH-FACTOR | IDENTIFICATION | MICRORNA EXPRESSION | LINEAGE | NEUROSCIENCES | Central Nervous System - metabolism | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | S100 Proteins - genetics | Oligodendroglia - drug effects | Basic Helix-Loop-Helix Transcription Factors - metabolism | Animals, Newborn | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptor, Platelet-Derived Growth Factor alpha - metabolism | S100 Calcium Binding Protein beta Subunit | Oligonucleotide Array Sequence Analysis - methods | Rats | Mice, Transgenic | Oligodendrocyte Transcription Factor 2 | Myelin Proteins - genetics | Rats, Sprague-Dawley | Nerve Growth Factors - genetics | Mice | MicroRNAs - genetics | Myelin Proteins - metabolism | SOXD Transcription Factors - genetics | Optic Nerve - metabolism | Age Factors | SOXD Transcription Factors - metabolism | Gene Expression Regulation, Developmental - genetics | Sciatic Nerve - growth & development | Myelin Sheath - metabolism | Central Nervous System - growth & development | DNA-Binding Proteins - metabolism | Sciatic Nerve - metabolism | Oligodendroglia - physiology | Transfection | DEAD-box RNA Helicases - metabolism | Cell Differentiation - physiology | Optic Nerve - growth & development | Brain - cytology | 2',3'-Cyclic-Nucleotide Phosphodiesterases - genetics | Ribonuclease III - genetics | Ribonuclease III - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Profiling - methods | Transcription Factors - genetics | 2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | DEAD-box RNA Helicases - genetics | Animals | Cell Differentiation - drug effects | Receptor, Platelet-Derived Growth Factor alpha - genetics | Stem Cells - drug effects | Stem Cells - physiology | Proteins | Genotype & phenotype | Gene expression | Experiments | Rodents | Cell cycle | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 450 - 455
Adipose tissue is a major site of energy storage and has a role in the regulation of metabolism through the release of adipokines. Here we show that mice with... 
CELLS | EXTRACELLULAR VESICLES | RNA | METABOLISM | MEMBRANE-VESICLES | MICRORNA BIOGENESIS | MULTIDISCIPLINARY SCIENCES | EXOSOMES | HUMAN OBESITY | MICROVESICLES | DIFFERENTIATION | Adipose Tissue, White - transplantation | Adipose Tissue, Brown - secretion | 3' Untranslated Regions - genetics | Adipose Tissue, White - metabolism | Fibroblast Growth Factors - genetics | Exosomes - genetics | Male | MicroRNAs - metabolism | Adipose Tissue, White - secretion | Adipose Tissue - metabolism | Organ Specificity - genetics | Transcription, Genetic | Adipose Tissue - secretion | Glucose Tolerance Test | Ribonuclease III - genetics | Paracrine Communication | Liver - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Genes, Reporter - genetics | Adipokines - metabolism | Ribonuclease III - deficiency | Adipose Tissue, Brown - transplantation | Adipose Tissue, Brown - cytology | Animals | Fibroblast Growth Factors - blood | Models, Biological | Adipose Tissue, Brown - metabolism | Mice | MicroRNAs - blood | MicroRNAs - genetics | Adipose Tissue - transplantation | RNA sequencing | Physiological aspects | MicroRNA | Gene expression | Observations | Methods | Enzymes | Adipocytes | Metabolism | Rodents | MicroRNAs | Index Medicus | Obesity | Brown fat | Lipodystrophy | Tissue crosstalk | Exosomes | Metabolic syndrome | FGF21
Journal Article