X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (747) 747
Publication (62) 62
Book Review (55) 55
Book Chapter (9) 9
Book / eBook (4) 4
Conference Proceeding (1) 1
Dissertation (1) 1
Newsletter (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (704) 704
animals (447) 447
humans (345) 345
biochemistry & molecular biology (268) 268
ribonucleases - antagonists & inhibitors (238) 238
ribonuclease, pancreatic - metabolism (192) 192
ribonuclease, pancreatic - antagonists & inhibitors (188) 188
kinetics (152) 152
cattle (149) 149
ribonuclease (145) 145
angiogenin (143) 143
mice (126) 126
ribonuclease, pancreatic - chemistry (106) 106
male (93) 93
amino acid sequence (90) 90
proteins (90) 90
ribonucleases - metabolism (89) 89
models, molecular (88) 88
molecular sequence data (88) 88
binding sites (85) 85
protein (85) 85
cancer (83) 83
female (82) 82
pancreas - enzymology (82) 82
cell biology (80) 80
protein binding (79) 79
biophysics (77) 77
hydrogen-ion concentration (75) 75
expression (74) 74
angiogenesis (69) 69
protein conformation (69) 69
rats (69) 69
enzyme inhibitors - pharmacology (67) 67
ribonuclease, pancreatic - genetics (66) 66
ribonuclease inhibitor (59) 59
cell line, tumor (58) 58
enzyme inhibitors - chemistry (58) 58
oncology (58) 58
endothelial-cells (56) 56
ribonuclease a (54) 54
enzymes (53) 53
biochemistry (52) 52
binding (51) 51
research (51) 51
ribonuclease, pancreatic (51) 51
cells (47) 47
proteins - chemistry (47) 47
rna (47) 47
molecular weight (45) 45
site-directed mutagenesis (45) 45
multidisciplinary sciences (44) 44
article (43) 43
analysis (41) 41
crystal-structure (41) 41
ribonucleases (41) 41
enzyme inhibitors - metabolism (40) 40
base sequence (39) 39
crystallography, x-ray (38) 38
tumor-growth (38) 38
human angiogenin (37) 37
proteins - metabolism (37) 37
cells, cultured (36) 36
in-vivo (36) 36
ribonuclease, pancreatic - pharmacology (36) 36
chromatography, gel (35) 35
gene expression (34) 34
in vitro techniques (34) 34
structure-activity relationship (34) 34
substrate specificity (34) 34
chemistry (33) 33
ribonucleases - chemistry (33) 33
cell line (32) 32
endothelial growth-factor (32) 32
pancreatic ribonuclease (31) 31
pharmacology & pharmacy (31) 31
rna, messenger - metabolism (31) 31
time factors (31) 31
cell proliferation - drug effects (30) 30
molecular structure (30) 30
apoptosis (29) 29
cell proliferation (29) 29
ribonucleases - isolation & purification (29) 29
ribonucleases - pharmacology (29) 29
thermodynamics (29) 29
chemical phenomena (28) 28
inhibition (28) 28
eosinophil-derived neurotoxin (27) 27
human pancreatic ribonuclease (27) 27
monoclonal-antibody (27) 27
swine (27) 27
antineoplastic agents - pharmacology (26) 26
chemistry, medicinal (26) 26
hormones, hormone substitutes, and hormone antagonists (26) 26
protein folding (26) 26
tumors (26) 26
purification (25) 25
temperature (25) 25
amino acids - analysis (24) 24
catalysis (24) 24
cell nucleus - metabolism (24) 24
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (4) 4
UofT at Mississauga - Stacks (2) 2
Chemistry (A D Allen) - Stacks (1) 1
Collection Dvlpm't (Acquisitions) - Closed Orders (1) 1
Gerstein Science - Not Returned (1) 1
Online Resources - Online (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. 4476 - 4481
Inhibition of the vascular endothelial growth factor (VEGF) pathway has failed to improve overall survival of patients with glioblastoma (GBM). We previously... 
Anti-angiogenic therapy | Macrophage polarization | Tumor microenvironment | Microglia reprogramming | Anti-tumor immunity | anti-angiogenic therapy | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | macrophage polarization | RANDOMIZED-TRIAL | ANGIOPOIETIN-2 | CANCER | THERAPY | microglia reprogramming | TIE2-EXPRESSING MONOCYTES | BLOOD-VESSELS | TUMOR-ASSOCIATED MACROPHAGES | tumor microenvironment | NORMALIZATION | anti-tumor immunity | ENDOTHELIAL GROWTH-FACTOR | Macrophages - pathology | Antibodies, Bispecific - pharmacology | Vesicular Transport Proteins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neoplasms, Experimental - pathology | Xenograft Model Antitumor Assays | Macrophages - metabolism | Vesicular Transport Proteins - antagonists & inhibitors | Animals | Antibodies, Neoplasm - pharmacology | Ribonuclease, Pancreatic - metabolism | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Mice | Neoplasms, Experimental - metabolism | Glioblastoma - drug therapy | Ribonuclease, Pancreatic - antagonists & inhibitors | Neoplasms, Experimental - drug therapy | Viral antibodies | Care and treatment | Antibodies | Physiological aspects | Models | Macrophages | Vascular endothelial growth factor | Health aspects | Glioblastoma multiforme | Genotype & phenotype | Survival analysis | Protein expression | Cells | Tumors | Cancer | Index Medicus | Biological Sciences
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. 4470 - 4475
Glioblastomas (GBMs) rapidly become refractory to anti-VEGF therapies. We previously demonstrated that ectopic overexpression of angiopoietin-2 (Ang-2)... 
Anti-angiogenic therapy | Colony-stimulating factor 1 | Tumor immunity | Tumor microenvironment | Macrophage | anti-angiogenic therapy | ANGIOPOIETIN-2 FUNCTIONS | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | macrophage | BEVACIZUMAB PLUS IRINOTECAN | RANDOMIZED-TRIAL | ANTIBODY | tumor immunity | KINASE INHIBITOR | ANTIANGIOGENIC THERAPY | PHASE-II TRIAL | colony-stimulating factor 1 | tumor microenvironment | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Macrophages - pathology | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neovascularization, Pathologic - pathology | Neoplasms, Experimental - pathology | Macrophages - metabolism | Animals | Antibodies, Neoplasm - pharmacology | Receptors, Vascular Endothelial Growth Factor - metabolism | Ribonuclease, Pancreatic - metabolism | Neovascularization, Pathologic - drug therapy | Glioblastoma - pathology | Cell Line, Tumor | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Glioblastoma - metabolism | Mice | Neovascularization, Pathologic - metabolism | Neoplasms, Experimental - metabolism | Glioblastoma - drug therapy | Quinazolines - pharmacology | Ribonuclease, Pancreatic - antagonists & inhibitors | Neoplasms, Experimental - drug therapy | Drug Screening Assays, Antitumor | Survival analysis | Gene expression | Kinases | Cells | Tumors | Cancer | Index Medicus | Biological Sciences
Journal Article
Journal Article
Angiogenesis, ISSN 0969-6970, 10/2013, Volume 16, Issue 4, pp. 903 - 917
Hypoxia-inducible factors (HIFs) and STAT-3 play essential roles in angiogenesis. HIF-1α and STAT-3 are clients of the heat shock protein 90 (HSP90). We... 
HSP90 | Angiogenesis | Biomedicine | Cancer Research | Oncology | HIF-1α | STAT-3 | Ophthalmology | Cardiology | Biomedicine general | Cell Biology | CELLS | HIF-1 alpha | HEAT-SHOCK-PROTEIN-90 | HYPOXIA | HIF-1 | THERAPY | O-2 | PERIPHERAL VASCULAR DISEASE | TUMOR-GROWTH | EXPRESSION | Adenocarcinoma - pathology | Humans | Vesicular Transport Proteins - biosynthesis | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Gene Knockdown Techniques | Ribonuclease, Pancreatic - biosynthesis | RNA, Messenger - biosynthesis | Vesicular Transport Proteins - antagonists & inhibitors | Laminin | Platelet-Derived Growth Factor - biosynthesis | Rectal Neoplasms - genetics | STAT3 Transcription Factor - physiology | Rectal Neoplasms - pathology | Ribonuclease, Pancreatic - antagonists & inhibitors | Rectal Neoplasms - drug therapy | STAT3 Transcription Factor - genetics | Transforming Growth Factor beta1 - biosynthesis | Triazoles - therapeutic use | Proteoglycans | Specific Pathogen-Free Organisms | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Down-Regulation | Ribonuclease, Pancreatic - genetics | Angiogenesis Inhibitors - pharmacology | Adenocarcinoma - drug therapy | Chick Embryo | Adenocarcinoma - blood supply | Fibroblast Growth Factor 2 - antagonists & inhibitors | Fibroblast Growth Factor 2 - genetics | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Mice, Nude | Cell Line, Tumor | Human Umbilical Vein Endothelial Cells | Vascular Endothelial Growth Factor A - biosynthesis | Transforming Growth Factor beta1 - antagonists & inhibitors | HSP90 Heat-Shock Proteins - physiology | Gene Expression Regulation, Neoplastic | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Platelet-Derived Growth Factor - genetics | HEK293 Cells | Angiogenesis Inhibitors - therapeutic use | Female | Antineoplastic Agents - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - physiology | Chorioallantoic Membrane - blood supply | Colorectal Neoplasms - blood supply | Vesicular Transport Proteins - genetics | Fibroblast Growth Factor 2 - biosynthesis | Transforming Growth Factor beta1 - genetics | Triazoles - pharmacology | Xenograft Model Antitumor Assays | Animals | Collagen | Colorectal Neoplasms - pathology | STAT3 Transcription Factor - antagonists & inhibitors | Platelet-Derived Growth Factor - antagonists & inhibitors | Drug Combinations | Index Medicus
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2016, Volume 30, Issue 6, pp. 953 - 967
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 51, pp. 42708 - 42725
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2014, Volume 136, Issue 22, pp. 7817 - 7820
Journal Article