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Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6306, pp. 1399 - 1405
Journal Article
Journal Article
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2009, Volume 85, Issue 5, pp. 617 - 627
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 18, pp. 4739 - 4744
Pre-mRNA splicing is an essential step of eukaryotic gene expression that requires both high efficiency and high fidelity. Prp8 has long been considered the... 
Spliceosome | Lariat sequencing | Prp8 | Splicing fidelity | Splicing efficiency | SPLICEOSOME ACTIVATION | splicing efficiency | MULTIDISCIPLINARY SCIENCES | spliceosome | SACCHAROMYCES-CEREVISIAE | YEAST | splicing fidelity | ANGSTROM RESOLUTION | U4/U6.U5 TRI-SNRNP | ALLELES MODULATE | lariat sequencing | GENETIC INTERACTIONS | BRANCH-POINTS | CRYO-EM STRUCTURE | EXON LIGATION | Saccharomyces cerevisiae - genetics | RNA, Fungal - chemistry | Ribonucleoprotein, U5 Small Nuclear - metabolism | Ribonuclease H | Saccharomyces cerevisiae Proteins - genetics | Ribonucleoprotein, U4-U6 Small Nuclear - metabolism | Ribonucleoprotein, U5 Small Nuclear - genetics | Saccharomyces cerevisiae - chemistry | RNA, Fungal - metabolism | RNA Splicing - physiology | Saccharomyces cerevisiae - metabolism | Ribonucleoprotein, U4-U6 Small Nuclear - genetics | Alleles | Saccharomyces cerevisiae Proteins - metabolism | Protein Domains | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | RNA, Fungal - genetics | Mutation | Ribonucleoprotein, U5 Small Nuclear - chemistry | Saccharomyces cerevisiae Proteins - chemistry | RNA sequencing | Physiological aspects | Messenger RNA | Methods | Fidelity | Errors | Eukaryotes | Splicing | Efficiency | Crosslinking | In vitro testing | Catalysis | Ribonucleic acid--RNA | Gene expression | Index Medicus | Biological Sciences
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 01/2009, Volume 16, Issue 1, pp. 42 - 48
The spliceosome is a highly dynamic machine requiring multiple RNA-dependent ATPases of the DExD/H-box family. A fundamental unanswered question is how their... 
PROTEIN FAMILY | SPLICEOSOME ACTIVATION | DOMAIN | SPLICING FACTOR PRP8 | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SACCHAROMYCES-CEREVISIAE | DOMINANT RETINITIS-PIGMENTOSA | CELL BIOLOGY | BIOPHYSICS | BOX RNA HELICASE | U6 SNRNAS | FACTOR GENES | RNA Helicases - metabolism | Spliceosomes - genetics | Saccharomyces cerevisiae - genetics | Humans | RNA-Binding Proteins | Ribonucleoprotein, U4-U6 Small Nuclear - metabolism | Ribonucleoprotein, U5 Small Nuclear | Saccharomyces cerevisiae - metabolism | Genes, Dominant | Adenosine Triphosphate - metabolism | RNA Splicing - genetics | Protein Denaturation | RNA Helicases - genetics | RNA, Fungal - genetics | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Recombinant Proteins - chemistry | Retinitis Pigmentosa - genetics | Saccharomyces cerevisiae Proteins - genetics | Carrier Proteins - genetics | Peptide Fragments - chemistry | Carrier Proteins - metabolism | Ribonucleoprotein, U4-U6 Small Nuclear - genetics | Saccharomyces cerevisiae Proteins - metabolism | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | Mutation | Saccharomyces cerevisiae - growth & development | Saccharomyces cerevisiae Proteins - chemistry | Nucleoproteins | Physiological aspects | Research | Structure | Helicases | Health aspects | Adenosine triphosphatase | Proteins | Adenosine | Catalysis | Ribonucleic acid--RNA | Molecular biology | Index Medicus | retinitis pigmentosa | spliceosome | protein co-factor | pre-mRNA splicing
Journal Article
RNA, ISSN 1355-8382, 05/2011, Volume 17, Issue 5, pp. 799 - 808
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30125 - 30138
Journal Article