X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (13107) 13107
Publication (3385) 3385
Book Chapter (138) 138
Book Review (114) 114
Conference Proceeding (46) 46
Book / eBook (21) 21
Dissertation (7) 7
Government Document (2) 2
Newsletter (2) 2
Reference (2) 2
Web Resource (2) 2
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
biochemistry & molecular biology (6867) 6867
humans (6846) 6846
animals (5479) 5479
index medicus (4044) 4044
molecular sequence data (3851) 3851
ribonucleoproteins - metabolism (3481) 3481
cell biology (3183) 3183
base sequence (3010) 3010
amino acid sequence (2440) 2440
protein binding (2345) 2345
proteins (2249) 2249
rna (2228) 2228
ribonucleoproteins - genetics (1875) 1875
rna, messenger - metabolism (1851) 1851
hela cells (1827) 1827
rna-binding proteins - metabolism (1781) 1781
mice (1737) 1737
binding sites (1518) 1518
nucleic acid conformation (1446) 1446
ribonucleoproteins - chemistry (1446) 1446
rna splicing (1440) 1440
ribonucleoproteins (1433) 1433
messenger-rna (1374) 1374
research (1313) 1313
research article (1253) 1253
article (1205) 1205
mutation (1196) 1196
protein (1192) 1192
gene expression (1154) 1154
identification (1142) 1142
cell line (1113) 1113
rna-binding proteins - genetics (1093) 1093
rna, messenger - genetics (1067) 1067
nuclear proteins - metabolism (1027) 1027
expression (1010) 1010
saccharomyces-cerevisiae (1002) 1002
cell nucleus - metabolism (993) 993
rna precursors - metabolism (971) 971
pre-messenger-rna (962) 962
female (950) 950
rna - metabolism (950) 950
transcription, genetic (947) 947
models, molecular (932) 932
binding (862) 862
protein structure, tertiary (818) 818
ribonucleic acid--rna (798) 798
multidisciplinary sciences (791) 791
male (790) 790
genetics & heredity (789) 789
biophysics (781) 781
molecular biology (775) 775
rats (756) 756
sequence homology, amino acid (753) 753
ribonucleoproteins, small nuclear - metabolism (751) 751
analysis (749) 749
yeast (748) 748
biochemistry (747) 747
heterogeneous-nuclear ribonucleoproteins (741) 741
transcription (736) 736
saccharomyces cerevisiae - genetics (729) 729
messenger rna (725) 725
cloning, molecular (724) 724
molecular weight (724) 724
rna-binding proteins - chemistry (724) 724
gene (719) 719
gene-expression (719) 719
ribonucleoprotein (718) 718
cells (709) 709
protein biosynthesis (702) 702
phosphorylation (696) 696
rna-binding proteins (694) 694
dna (688) 688
in-vitro (680) 680
genes (664) 664
crystal-structure (660) 660
alternative splicing (653) 653
nuclear proteins - genetics (645) 645
complex (644) 644
gene expression regulation (642) 642
physiological aspects (638) 638
spliceosomes - metabolism (638) 638
in-vivo (624) 624
ribonucleoproteins, small nuclear (616) 616
genetic aspects (614) 614
ribonucleoproteins - isolation & purification (592) 592
introns (584) 584
rna, small nuclear - metabolism (572) 572
saccharomyces cerevisiae - metabolism (561) 561
protein conformation (559) 559
rna precursors - genetics (558) 558
small nuclear ribonucleoprotein (556) 556
splicing (554) 554
exons (553) 553
kinetics (545) 545
sequence alignment (538) 538
rna - chemistry (534) 534
biology (530) 530
cell line, tumor (520) 520
localization (508) 508
translation (499) 499
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (13106) 13106
Russian (38) 38
Japanese (11) 11
Chinese (10) 10
German (8) 8
French (4) 4
Dutch (1) 1
Hungarian (1) 1
Italian (1) 1
Korean (1) 1
Polish (1) 1
Slovak (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Molecular Cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 208 - 219
Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA-binding proteins containing disordered regions. We... 
TRANSITION | EUKARYOTIC STRESS GRANULES | CELL-FREE FORMATION | PRION-LIKE DOMAINS | NUCLEOLI | BEHAVIOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGIONS | BODIES | P GRANULES | AGGREGATION | CELL BIOLOGY | Organelles - chemistry | Fluorescence Recovery After Photobleaching | Humans | Polyethylene Glycols - chemistry | Amyloid - chemistry | Cytoplasmic Granules - chemistry | Molecular Mimicry | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Solutions | Cytoplasmic Granules - metabolism | Escherichia coli - metabolism | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - genetics | Protein Aggregation, Pathological - genetics | RNA - metabolism | Sodium Chloride - chemistry | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amyloid - genetics | Gene Expression | Recombinant Proteins - chemistry | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism | Recombinant Proteins - genetics | RNA - chemistry | Intrinsically Disordered Proteins - genetics | Heterogeneous Nuclear Ribonucleoprotein A1 | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - chemistry | Escherichia coli - genetics | Intrinsically Disordered Proteins - chemistry | Protein Binding | Organelles - metabolism | Protein Aggregation, Pathological - metabolism | Intrinsically Disordered Proteins - metabolism | Fluorescence | Marine biology | Chemical properties | RNA | Binding proteins | Protein binding | Yuan (China)
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7660, pp. 617 - 621
Intron removal requires assembly of the spliceosome on precursor mRNA (pre-mRNA) and extensive remodelling to form the spliceosome's catalytic centre. Here we... 
U4/U6.U5 TRI-SNRNP | COMPLEX | PROTEIN | MESSENGER-RNA | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | U2 SNRNP | CRYO-EM STRUCTURE | REQUIRES ATP | RNA Helicases - metabolism | Ribonucleoprotein, U2 Small Nuclear - chemistry | Spliceosomes - chemistry | Saccharomyces cerevisiae - genetics | Ribonucleoprotein, U5 Small Nuclear - metabolism | RNA Splicing Factors - chemistry | RNA Helicases - chemistry | Ribonucleoprotein, U4-U6 Small Nuclear - metabolism | RNA Helicases - ultrastructure | RNA Splicing Factors - metabolism | Spliceosomes - metabolism | RNA Splicing | Ribonucleoprotein, U2 Small Nuclear - metabolism | Base Sequence | Protein Domains | RNA Precursors - metabolism | Ribonucleoproteins, Small Nuclear - chemistry | Protein Stability | Ribonucleoprotein, U5 Small Nuclear - chemistry | Saccharomyces cerevisiae Proteins - ultrastructure | Catalytic Domain | Biocatalysis | Introns - genetics | RNA Splice Sites - genetics | Models, Molecular | Nuclear Proteins - metabolism | RNA Precursors - genetics | Spliceosomes - ultrastructure | Nuclear Proteins - chemistry | Saccharomyces cerevisiae - chemistry | Cryoelectron Microscopy | RNA Precursors - ultrastructure | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | RNA, Small Nuclear - chemistry | RNA, Small Nuclear - metabolism | Ribonucleoproteins, Small Nuclear - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Yeast | Ribonucleoproteins (small nuclear) | Molecular structure | mRNA | Saccharomyces | Ribonucleoproteins (U2 small nuclear) | Electron microscopy | Ribonucleic acid--RNA | snRNA | Proteins | DNA helicase | Transmission electron microscopy | Ribonucleic acids | Catalysis | Atomic structure | Saccharomyces cerevisiae
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 31, pp. 12764 - 12771
Eukaryotic cells contain hundreds of metalloproteins that are supported by intracellular systems coordinating the uptake and distribution of metal cofactors.... 
metalloprotein | HUMAN BOLA2 | HEME-BIOSYNTHESIS | DEOXYHYPUSINE HYDROXYLASE | BolA2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | glutaredoxin | SACCHAROMYCES-CEREVISIAE | iron metabolism | molecular chaperone | PHP4 FUNCTION | FERRITIN DEGRADATION | poly C-binding protein | IN-VIVO | GENE-EXPRESSION | iron | iron-sulfur protein | SULFUR CLUSTER | MONOTHIOL GLUTAREDOXIN | Molecular Chaperones - metabolism | Humans | Protein Multimerization | Iron-Sulfur Proteins - chemistry | Molecular Chaperones - chemistry | Nuclear Receptor Coactivators - chemistry | Autophagy | Apoferritins - metabolism | Ferritins - metabolism | Cation Transport Proteins - metabolism | Apoenzymes - metabolism | Carrier Proteins - chemistry | Dimerization | Nuclear Receptor Coactivators - metabolism | Erythroid Precursor Cells - cytology | RNA-Binding Proteins - chemistry | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Models, Molecular | Apoferritins - chemistry | Iron - metabolism | Protein Transport | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Models, Biological | Heterogeneous-Nuclear Ribonucleoproteins - chemistry | Apoenzymes - chemistry | Erythroid Precursor Cells - metabolism | Cytosol - metabolism | Iron-Sulfur Proteins - metabolism | Proteins - chemistry | Cation Transport Proteins - chemistry | Ferritins - chemistry | RNA-Binding Proteins - metabolism | iron–sulfur protein | Minireviews
Journal Article
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7641, pp. 318 - 323
Spliceosome rearrangements facilitated by RNA helicase PRP16 before catalytic step two of splicing are poorly understood. Here we report a 3D cryo-electron... 
2ND STEP | I SPLICEOSOME | U4/U6.U5 TRI-SNRNP | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MOLECULAR ARCHITECTURE | CATALYTIC CORE | PRE-MESSENGER-RNA | PRP8 | INSIGHTS | Spliceosomes - chemistry | Humans | Cell Cycle Proteins - ultrastructure | RNA Splicing Factors - chemistry | RNA, Messenger - metabolism | RNA Splicing Factors - metabolism | Cell Cycle Proteins - chemistry | Spliceosomes - metabolism | RNA Splicing | Ribonucleoproteins, Small Nuclear - ultrastructure | Base Sequence | Protein Domains | Ribonucleoproteins, Small Nuclear - chemistry | DEAD-box RNA Helicases - metabolism | DEAD-box RNA Helicases - chemistry | Biocatalysis | Introns - genetics | Movement | RNA, Messenger - genetics | RNA-Binding Proteins - chemistry | Cell Cycle Proteins - metabolism | Models, Molecular | Exons - genetics | Spliceosomes - ultrastructure | RNA Stability | Saccharomyces cerevisiae - chemistry | Cryoelectron Microscopy | RNA-Binding Proteins - ultrastructure | RNA Splicing Factors - ultrastructure | Ribonuclease H - chemistry | Adenosine - metabolism | Saccharomyces cerevisiae - enzymology | RNA, Messenger - chemistry | DEAD-box RNA Helicases - ultrastructure | RNA-Binding Proteins - metabolism | Ribonucleoproteins, Small Nuclear - metabolism | Ribonuclease H - metabolism | Genetic research | Genetic engineering | Research | Methods | RNA splicing | Proteins | Yeast | Catalysis | Molecular structure | Microscopy | Ribonucleic acid--RNA
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7605, pp. 133 - 137
Ribosome biogenesis is a highly complex process in eukaryotes, involving temporally and spatially regulated ribosomal protein (r-protein) binding and ribosomal... 
REFINEMENT | COMPLEX | RNA | BIOGENESIS | INITIATION | MULTIDISCIPLINARY SCIENCES | RESOLUTION | MATURATION | IDENTIFICATION | ASSOCIATION | SUBUNIT | RNA, Fungal - ultrastructure | GTP Phosphohydrolases - ultrastructure | Saccharomyces cerevisiae - ultrastructure | DNA, Ribosomal Spacer - metabolism | RNA, Ribosomal - genetics | GTP Phosphohydrolases - chemistry | Saccharomyces cerevisiae - metabolism | Cell Nucleus - metabolism | Ribosome Subunits, Large, Eukaryotic - metabolism | DNA, Ribosomal Spacer - genetics | Base Sequence | DNA, Ribosomal Spacer - ultrastructure | Ribosome Subunits, Large, Eukaryotic - chemistry | Models, Molecular | Ribonucleoproteins - metabolism | Nuclear Proteins - chemistry | Saccharomyces cerevisiae - chemistry | RNA, Ribosomal - ultrastructure | Saccharomyces cerevisiae - cytology | Ribosomal Proteins - isolation & purification | GTP Phosphohydrolases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | GTP-Binding Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Ribosomal Proteins - chemistry | Ribosome Subunits, Large, Eukaryotic - ultrastructure | Nuclear Proteins - ultrastructure | Molecular Sequence Data | Cytoplasm - metabolism | Ribosomal Proteins - metabolism | Ribosomal Proteins - ultrastructure | Saccharomyces cerevisiae Proteins - isolation & purification | RNA, Fungal - genetics | Active Transport, Cell Nucleus | Ribonucleoproteins - chemistry | Saccharomyces cerevisiae Proteins - ultrastructure | Catalytic Domain | GTP-Binding Proteins - chemistry | RNA, Ribosomal - metabolism | Nuclear Proteins - metabolism | GTP-Binding Proteins - ultrastructure | DNA, Ribosomal Spacer - chemistry | Cell Nucleus - ultrastructure | Rotation | RNA, Fungal - metabolism | Cryoelectron Microscopy | Protein Binding | Cell Nucleus - chemistry | Ribonucleoproteins - ultrastructure | Nucleolus organizer region | Protein research | Research | Ribosomes | Protein binding | Genetic research | Proteins | Polypeptides | Molecular structure | Ribonucleic acid--RNA
Journal Article
Biochemistry, ISSN 0006-2960, 06/2015, Volume 54, Issue 23, pp. 3694 - 3706
In an earlier study, beta(3)-puromycin was used for the selection of modified ribosomes, which were utilized for the incorporation of five different beta-amino... 
NONNATURAL RESIDUES | STRUCTURAL BASIS | GAMMA-PEPTIDES | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIPEPTIDE FORMATION | PEPTIDE-BOND FORMATION | ACTIVATED TRANSFER-RNAS | DNA-BINDING PROTEINS | GENE-EXPRESSION | SITE-SPECIFIC INCORPORATION | MISACYLATED TRANSFER-RNAS | Peptidyl Transferases - genetics | Tetrahydrofolate Dehydrogenase - chemistry | Stereoisomerism | Humans | RNA, Transfer, Amino Acyl - chemistry | Heterogeneous-Nuclear Ribonucleoprotein L - chemistry | Ribosomes - metabolism | Substrate Specificity | Alanine - chemistry | Recombinant Proteins - biosynthesis | Alanine - analogs & derivatives | Nucleotide Motifs | Escherichia coli Proteins - biosynthesis | Escherichia coli - metabolism | RNA, Transfer, Amino Acyl - metabolism | Heterogeneous-Nuclear Ribonucleoprotein L - genetics | Protein Stability | RNA, Bacterial - metabolism | Peptidyl Transferases - metabolism | Escherichia coli - enzymology | Puromycin - metabolism | RNA, Ribosomal - chemistry | Mutant Proteins - genetics | Models, Molecular | RNA, Ribosomal - metabolism | Recombinant Proteins - chemistry | Alanine - metabolism | Puromycin - chemistry | Tetrahydrofolate Dehydrogenase - biosynthesis | Molecular Dynamics Simulation | Mutant Proteins - biosynthesis | RNA, Ribosomal, 23S - chemistry | Puromycin - analogs & derivatives | Hydrogen Bonding | Heterogeneous-Nuclear Ribonucleoprotein L - biosynthesis | Mutant Proteins - chemistry | RNA, Bacterial - chemistry | Protein Conformation | Escherichia coli Proteins - chemistry | RNA, Ribosomal, 23S - metabolism | Protein biosynthesis | Research | Structure | Ribosomes | Puromycin
Journal Article
Science, ISSN 0036-8075, 12/2012, Volume 338, Issue 6114, pp. 1634 - 1637
The influenza viruses cause annual epidemics of respiratory disease and occasional pandemics, which constitute a major public-health issue. The segmented... 
Pandemics | RNA | Particle interactions | Virions | REPORTS | Ribonucleoproteins | Orthomyxoviridae | Viruses | Viral morphology | Atomic structure | Monomers | LOCALIZATION | NUCLEAR | REPLICATION | PARTICLES | RECONSTRUCTION | MULTIDISCIPLINARY SCIENCES | COMPLEXES | POLYMERASE | A VIRUS NUCLEOPROTEIN | OLIGOMERIZATION | Viral Core Proteins - ultrastructure | RNA Replicase - metabolism | Influenza A Virus, H1N1 Subtype - physiology | Virion - chemistry | Viral Proteins - metabolism | Influenza A Virus, H1N1 Subtype - ultrastructure | RNA Replicase - ultrastructure | Cell Nucleus - metabolism | Cell Nucleus - virology | Madin Darby Canine Kidney Cells | Viral Core Proteins - metabolism | Transcription, Genetic | RNA, Viral - metabolism | Ribonucleoproteins - chemistry | Viral Core Proteins - chemistry | Protein Structure, Secondary | Electron Microscope Tomography | Viral Proteins - chemistry | RNA-Binding Proteins - chemistry | Models, Molecular | Ribonucleoproteins - metabolism | Viral Proteins - ultrastructure | Microscopy, Electron | Cryoelectron Microscopy | RNA-Binding Proteins - ultrastructure | Animals | RNA, Viral - chemistry | Image Processing, Computer-Assisted | RNA Replicase - chemistry | Virion - ultrastructure | Protein Conformation | Influenza A Virus, H1N1 Subtype - chemistry | Ribonucleoproteins - ultrastructure | RNA-Binding Proteins - metabolism | Influenza viruses | Properties | RNA-protein interactions | Influenza | Genomics | Virology | Ribonucleic acids | Mortality | Replication | Genomes | Online | Assembly
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 537, Issue 7619, pp. 197 - 201
Precursor mRNA (pre-mRNA) splicing proceeds by two consecutive transesterification reactions via a lariat-intron intermediate. Here we present the 3.8 angstrom... 
U4/U6.U5 TRI-SNRNP | IN-VITRO | ELECTRON CRYOMICROSCOPY | ACTIVE-SITE | CRYSTAL-STRUCTURE | CONFORMATIONAL REARRANGEMENT | MULTIDISCIPLINARY SCIENCES | SACCHAROMYCES-CEREVISIAE | U6 SNRNA | PRE-MESSENGER-RNA | CATALYTIC ACTIVATION | RNA Precursors - chemistry | RNA Helicases - metabolism | Spliceosomes - chemistry | RNA, Fungal - ultrastructure | Saccharomyces cerevisiae - genetics | Ribonucleoprotein, U5 Small Nuclear - metabolism | Saccharomyces cerevisiae - ultrastructure | Ribonucleoprotein, U4-U6 Small Nuclear - metabolism | RNA Splicing Factors - metabolism | Spliceosomes - metabolism | RNA Splicing | RNA, Small Nuclear - genetics | Base Sequence | RNA Precursors - metabolism | RNA, Fungal - genetics | Ribonucleoprotein, U5 Small Nuclear - chemistry | Saccharomyces cerevisiae Proteins - ultrastructure | Catalytic Domain | Introns - genetics | RNA Splice Sites - genetics | RNA, Fungal - chemistry | Adenosine Triphosphatases - metabolism | Models, Molecular | Exons - genetics | Magnesium - metabolism | Nuclear Proteins - metabolism | Spliceosomes - ultrastructure | Esterification | Saccharomyces cerevisiae - chemistry | RNA, Fungal - metabolism | Cryoelectron Microscopy | RNA Precursors - ultrastructure | Base Pairing | Saccharomyces cerevisiae Proteins - metabolism | Adenosine - metabolism | Ribonucleoprotein, U4-U6 Small Nuclear - chemistry | RNA, Small Nuclear - chemistry | RNA, Small Nuclear - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Genetic aspects | Spliceosomes | Structure | Brewer's yeast | Methods | RNA splicing | Proteins | Enzymes | Molecular structure | Microscopy | Catalysis | Ribonucleic acid--RNA | Binding sites
Journal Article