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ribosemonophosphates - metabolism (83) 83
animals (81) 81
kinetics (59) 59
ribosemonophosphates - pharmacology (58) 58
humans (51) 51
biochemistry & molecular biology (42) 42
index medicus (25) 25
rats (25) 25
mice (23) 23
ribosemonophosphates (21) 21
male (20) 20
binding sites (19) 19
hydrogen-ion concentration (19) 19
phosphates - pharmacology (16) 16
substrate specificity (16) 16
cells, cultured (15) 15
escherichia-coli (15) 15
ribose-phosphate pyrophosphokinase - metabolism (15) 15
molecular sequence data (14) 14
pentosephosphates - metabolism (14) 14
phosphoribosyl pyrophosphate - metabolism (14) 14
ribosemonophosphates - chemistry (14) 14
enzymes (13) 13
liver - metabolism (13) 13
pentosephosphates - pharmacology (13) 13
phosphates (13) 13
cell line (12) 12
dose-response relationship, drug (12) 12
phosphorylation (12) 12
phosphotransferases - metabolism (12) 12
purine-nucleoside phosphorylase - metabolism (12) 12
sugars (12) 12
adenosine triphosphate - pharmacology (11) 11
dna - metabolism (11) 11
magnesium - pharmacology (11) 11
time factors (11) 11
enzyme inhibitors - pharmacology (10) 10
ligands (10) 10
molecular weight (10) 10
monosaccharides (10) 10
protein binding (10) 10
purification (10) 10
amino acid sequence (9) 9
female (9) 9
glucose - metabolism (9) 9
in vitro techniques (9) 9
liver - enzymology (9) 9
ribosemonophosphates - biosynthesis (9) 9
adenosine - metabolism (8) 8
adenosine diphosphate - pharmacology (8) 8
adenosine triphosphate - metabolism (8) 8
biophysics (8) 8
expression (8) 8
fluorouracil - metabolism (8) 8
inhibition (8) 8
mechanism (8) 8
metabolism (8) 8
pentose phosphate pathway (8) 8
pentosyltransferases - metabolism (8) 8
adenosine monophosphate - pharmacology (7) 7
base sequence (7) 7
biochemistry (7) 7
cattle (7) 7
escherichia coli - enzymology (7) 7
glycine - metabolism (7) 7
hydrolysis (7) 7
inosine - metabolism (7) 7
microbiology (7) 7
purines - biosynthesis (7) 7
ribose (7) 7
allosteric regulation (6) 6
analysis (6) 6
article (6) 6
cancer (6) 6
carcinoma, ehrlich tumor - metabolism (6) 6
dna repair (6) 6
electrophoresis, polyacrylamide gel (6) 6
enzyme activation (6) 6
glucose - pharmacology (6) 6
inosine - pharmacology (6) 6
liver - drug effects (6) 6
magnetic resonance spectroscopy (6) 6
methylene blue - pharmacology (6) 6
oxidation-reduction (6) 6
pathway (6) 6
pharmacology (6) 6
protein (6) 6
protein conformation (6) 6
purines - metabolism (6) 6
pyruvate kinase - metabolism (6) 6
rats, inbred strains (6) 6
research article (6) 6
ribosemonophosphates - analysis (6) 6
salmonella typhimurium - enzymology (6) 6
temperature (6) 6
thymidine phosphorylase (6) 6
uridine phosphorylase - metabolism (6) 6
adenosine - pharmacology (5) 5
aldehyde-lyases - metabolism (5) 5
amidophosphoribosyltransferase - metabolism (5) 5
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Journal Article
International Journal of Cancer, ISSN 0020-7136, 12/2006, Volume 119, Issue 12, pp. 2733 - 2741
The metabolic network of cancer cells confers adaptive mechanisms against many chemotherapeutic agents, but also presents critical constraints that make the... 
combined therapy | tumor growth inhibition | phase plane analysis | metabolic profiling | pentose phosphate pathway | Metabolic profiling | Phase plane analysis | Pentose phosphate pathway | Combined therapy | Tumor growth inhibition | SURVIVAL | OXYTHIAMINE | PHENOTYPE | TUMOR-CELLS | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE ACTIVITY | PROLIFERATION | DEHYDROEPIANDROSTERONE | METABOLIC-CONTROL ANALYSIS | INHIBITION | ONCOLOGY | GENE AMPLIFICATION | Methotrexate - pharmacology | Pentose Phosphate Pathway - drug effects | Nucleic Acid Synthesis Inhibitors - pharmacology | Humans | Carcinoma, Ehrlich Tumor - physiopathology | Dehydroepiandrosterone - administration & dosage | Oxythiamine - pharmacology | Dose-Response Relationship, Drug | Ribosemonophosphates - antagonists & inhibitors | Oxidation-Reduction - drug effects | Growth Inhibitors - pharmacology | Carcinoma, Ehrlich Tumor - pathology | Cell Survival - drug effects | Dehydroepiandrosterone - pharmacology | Nucleic Acid Synthesis Inhibitors - administration & dosage | Carcinoma, Ehrlich Tumor - drug therapy | Drug Synergism | HT29 Cells | Oxythiamine - administration & dosage | Animals | Growth Inhibitors - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cell Line, Tumor | Methotrexate - administration & dosage | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Ribosemonophosphates - metabolism | Drug Resistance, Neoplasm - drug effects
Journal Article
Cardiovascular and Hematological Agents in Medicinal Chemistry, ISSN 1871-5257, 01/2006, Volume 4, Issue 1, pp. 17 - 32
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 2001, Volume 78, Issue 4, pp. 890 - 898
Journal Article
Plant Physiology, ISSN 0032-0889, 7/2011, Volume 156, Issue 3, pp. 1337 - 1350
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase (np-Ga3PDHase) is a cytosolic unconventional glycolytic enzyme of plant cells regulated by... 
Phosphates | Enzymes | Phosphorylation | Dehydrogenases | Allosteric regulation | Endosperm | BIOCHEMICAL PROCESSES AND MACROMOLECULAR STRUCTURES | Plants | Spinach | Physiological regulation | Plant cells | ARABIDOPSIS-THALIANA | TISSUE DISTRIBUTION | SYNTHETIC PEPTIDES | BIOCHEMICAL-CHARACTERIZATION | SUCROSE-PHOSPHATE SYNTHASE | NITRATE REDUCTASE | HETEROTROPHIC CELLS | 3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE KINASE | CYTOSOLIC PYRUVATE-KINASE | DEVELOPING CASTOR | PLANT SCIENCES | Allosteric Regulation - drug effects | Organ Specificity - drug effects | Amino Acid Sequence | Glyceric Acids - pharmacology | Protein-Serine-Threonine Kinases - isolation & purification | Molecular Sequence Data | Endosperm - enzymology | Fructosediphosphates - pharmacology | Ribosemonophosphates - pharmacology | Endosperm - drug effects | Cations, Divalent - pharmacology | Phosphoserine - metabolism | Sequence Alignment | Peptides - metabolism | Models, Biological | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - chemistry | Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism | Kinetics | Phosphorylation - drug effects | Triticum - enzymology | Protein-Serine-Threonine Kinases - metabolism | Triticum - drug effects | Plant proteins | Genetic aspects | Research | Properties | Genetic regulation | Protein kinases | Wheat
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 01/2018, Volume 28, Issue 2, pp. 11 - 130
Aims: Deoxyribose-1-phosphate (dRP) is a proangiogenic paracrine stimulus released by cancer cells, platelets, and macrophages and acting on endothelial cells.... 
Original Research Communications | NADPH | Reactive Oxygen Species/metabolism | Cell Line | Neovascularization, Physiologic/drug effects | Endothelial Cells/drug effects | Oxidative Stress | Molecular Biology | angiogenesis | Humans | Clinical Biochemistry | Biochemistry | Vascular Endothelial Growth Factor A/metabolism | Journal Article | Cell Biology | NF-κB | endothelial | NOX | ROS | NADPH Oxidase 2/metabolism | Physiology | NF-kappa B/metabolism | Ribosemonophosphates/pharmacology | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL GROWTH-FACTOR | NF-B | HYPOXIA | NAD(P)H OXIDASE | IN-VITRO | GLUCOSE | ENDOTHELIAL-CELLS | ENDOCRINOLOGY & METABOLISM | INHIBITOR | THYMIDINE PHOSPHORYLASE | NOX2 | Neovascularization, Physiologic - drug effects | Reactive Oxygen Species - metabolism | Endothelial Cells - metabolism | NADPH Oxidase 2 - metabolism | NF-kappa B - metabolism | Ribosemonophosphates - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Endothelial Cells - drug effects | Phosphates | Reactive oxygen species | Innovations | Paracrine signalling | Immunoblotting | Activation | Macrophages | NAD(P)H oxidase | Vascularization | Proteins | Angiogenesis | Transfection | NOX4 protein | Transcription activation | CYBB protein | Vascular endothelial growth factor receptor 2 | Vascular endothelial growth factor | Sugar | Glucose transporter | NF-κB protein | Wounds | Superoxide | siRNA | Ribonucleic acid--RNA | Endothelial cells | Gene silencing | Electron paramagnetic resonance | Platelets | Human behavior | Transporter | Cancer
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 05/2016, Volume 6, Issue 1, p. 26937
Ribose-5-phosphate isomerase (RPI) belongs to the non-oxidative branch of the pentose phosphate pathway, catalysing the inter-conversion of... 
CRUZI | RIBOSE 5-PHOSPHATE ISOMERASE | METABOLISM | GENE | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | SUBCELLULAR-LOCALIZATION | BRUCEI | INFANTUM | LEISHMANIA-DONOVANI | VIRULENCE
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Journal Article
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