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Neuron, ISSN 0896-6273, 10/2012, Volume 76, Issue 2, pp. 325 - 337
Fragile X syndrome (FXS) is the leading inherited cause of autism and intellectual disability. Aberrant synaptic translation has been implicated in the... 
MAMMALIAN TARGET | RAPAMYCIN SIGNALING PATHWAY | FMR1 KNOCKOUT MOUSE | MESSENGER-RNA | MEMORY | LONG-TERM DEPRESSION | PHOSPHOINOSITIDE 3-KINASE-AKT-MAMMALIAN TARGET | TRANSLATION | MENTAL-RETARDATION PROTEIN | NEUROSCIENCES | MTOR | Electric Stimulation | Fragile X Syndrome - pathology | Male | Fragile X Mental Retardation Protein - metabolism | Synapses - genetics | Recognition (Psychology) - physiology | Phosphorylation - genetics | TOR Serine-Threonine Kinases - genetics | Ribosomal Protein S6 Kinases, 70-kDa - deficiency | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Membrane Potentials - drug effects | Synapses - drug effects | Maze Learning - physiology | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Dendritic Spines - physiology | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Behavior, Animal - physiology | Mice, Transgenic | Hippocampus - pathology | Mutation - genetics | Patch-Clamp Techniques | Phenotype | Analysis of Variance | Mice | Long-Term Synaptic Depression - genetics | Neurons - pathology | Membrane Potentials - genetics | Fragile X Syndrome - physiopathology | Extracellular Signal-Regulated MAP Kinases - metabolism | Long-Term Synaptic Depression - drug effects | Excitatory Postsynaptic Potentials - drug effects | Extracellular Signal-Regulated MAP Kinases - genetics | Exploratory Behavior - physiology | Neurons - classification | Female | Interpersonal Relations | Fragile X Syndrome - genetics | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Biophysics | Methoxyhydroxyphenylglycol - analogs & derivatives | Methoxyhydroxyphenylglycol - pharmacology | Motor Activity - genetics | Rotarod Performance Test | Animals | Fragile X Syndrome - prevention & control | Dendritic Spines - classification | Fragile X Mental Retardation Protein - genetics | In Vitro Techniques | Depression, Mental | Analysis | Genetic research | Protein biosynthesis | Genetic aspects | Fragile X syndrome | Genetic translation | Proteins | Phosphorylation | Brain research | Kinases | Protein synthesis | Rodents | Index Medicus | Animal models | Translation | Translation initiation | Pattern recognition | Mental retardation | Ribosomal protein S6 kinase | Autism | Dendritic spines | Molecular modelling | Social interactions | Etiology | p70 S6 kinase | Long-term depression | Elongation
Journal Article
Cancer Cell, ISSN 1535-6108, 03/2012, Volume 21, Issue 3, pp. 374 - 387
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 7, pp. 1504 - 1515.e3
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 02/2010, Volume 30, Issue 4, pp. 908 - 921
Journal Article
Biochemical Journal, ISSN 0264-6021, 10/2010, Volume 431, Issue 2, pp. 245 - 255
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 497, Issue 7448, pp. 217 - 223
The mammalian target of rapamycin (mTOR), a phosphoinositide 3-kinase-related protein kinase, controls cell growth in response to nutrients and growth factors... 
MAMMALIAN TARGET | RAPTOR | BINDING PARTNER | RAG GTPASES | TOS MOTIF | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | PIK-RELATED KINASES | CELL-GROWTH | P70 S6 KINASE | RAPAMYCIN COMPLEX-1 | Adaptor Proteins, Signal Transducing - chemistry | Catalytic Domain - drug effects | TOR Serine-Threonine Kinases - metabolism | Pyridines - chemistry | Furans - pharmacology | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Pyrimidines - chemistry | TOR Serine-Threonine Kinases - antagonists & inhibitors | Indoles - metabolism | Furans - chemistry | Adenosine Triphosphate - metabolism | Indoles - pharmacology | Tacrolimus Binding Protein 1A - pharmacology | Naphthyridines - chemistry | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Purines - metabolism | Purines - pharmacology | MTOR Associated Protein, LST8 Homolog | Tacrolimus Binding Protein 1A - chemistry | Models, Molecular | Magnesium - metabolism | Pyrimidines - pharmacology | Sirolimus - metabolism | Sirolimus - pharmacology | Magnesium - chemistry | Purines - chemistry | TOR Serine-Threonine Kinases - chemistry | Tacrolimus Binding Protein 1A - metabolism | Pyridines - pharmacology | Sirolimus - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Adenosine Triphosphate - chemistry | Indoles - chemistry | Naphthyridines - pharmacology | Naphthyridines - metabolism | Protein Structure, Tertiary - drug effects | Proteins | Enzymes | Kinases | Crystal structure | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 09/2004, Volume 431, Issue 7005, pp. 200 - 205
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2016, Volume 126, Issue 5, pp. 1704 - 1716
A classic metabolic concept posits that insulin promotes energy storage and adipose expansion, while catecholamines stimulate release of adipose energy stores... 
MEDICINE, RESEARCH & EXPERIMENTAL | UNCOUPLING PROTEIN-1 GENE | WHITE FAT | GLUCOSE-HOMEOSTASIS | CYCLIC-AMP | ADIPOCYTE PROLIFERATION | INITIATION-FACTOR 4E | SMOOTH-MUSCLE-CELLS | ADULT HUMANS | DIET-INDUCED OBESITY | INSULIN SENSITIVITY | TOR Serine-Threonine Kinases - metabolism | Humans | Adipose Tissue, White - metabolism | Multiprotein Complexes - genetics | Uncoupling Protein 1 - biosynthesis | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Adipose Tissue, White - cytology | Cyclic AMP-Dependent Protein Kinases - genetics | TOR Serine-Threonine Kinases - genetics | HEK293 Cells | Regulatory-Associated Protein of mTOR | Insulin - genetics | Cyclic AMP-Dependent Protein Kinases - metabolism | Uncoupling Protein 1 - genetics | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - genetics | 3T3-L1 Cells | Mice, Knockout | Adipose Tissue, Brown - cytology | Insulin - metabolism | Animals | Receptors, Adrenergic, beta - genetics | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Adaptor Proteins, Signal Transducing - genetics | Signal Transduction - physiology | Adipose Tissue, Brown - metabolism | Mice | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2003, Volume 115, Issue 5, pp. 577 - 590
Journal Article