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The Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 8088 - 8095
We have examined CD40-dependent signals in endothelial cells (EC) mediating the expression of vascular endothelial growth factor (VEGF) and VEGF-induced... 
Phosphoproteins - immunology | Inflammation - pathology | RNA, Small Interfering - genetics | Transcriptional Activation - genetics | Humans | Transcriptional Activation - drug effects | Protein Biosynthesis - immunology | Transcriptional Activation - immunology | Promoter Regions, Genetic - drug effects | Vascular Endothelial Growth Factor A - genetics | CD40 Ligand - immunology | Ribosomal Protein S6 Kinases - immunology | Inflammation - metabolism | Phosphorylation - genetics | Adaptor Proteins, Signal Transducing - immunology | Regulatory-Associated Protein of mTOR | CD40 Antigens - genetics | Phosphorylation - immunology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Transcription Factors - immunology | Carrier Proteins - immunology | Fibroblasts - metabolism | Endothelial Cells - metabolism | Carrier Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - immunology | Signal Transduction - genetics | Proto-Oncogene Proteins c-akt - immunology | CD40 Ligand - genetics | Signal Transduction - drug effects | CD40 Ligand - pharmacology | Neoplasms - immunology | Fibroblasts - immunology | Protein Biosynthesis - drug effects | Anti-Bacterial Agents - pharmacology | Mice | TOR Serine-Threonine Kinases | Proteins - antagonists & inhibitors | CD40 Antigens - immunology | Neoplasms - metabolism | Vascular Endothelial Growth Factor A - biosynthesis | Ribosomal Protein S6 Kinases - metabolism | Multiprotein Complexes | Phosphoproteins - metabolism | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Mechanistic Target of Rapamycin Complex 1 | Signal Transduction - immunology | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Neoplasms - genetics | RNA, Small Interfering - immunology | Protein Biosynthesis - genetics | Rapamycin-Insensitive Companion of mTOR Protein | Inflammation - immunology | Phosphoproteins - genetics | Transcription Factors - genetics | Mice, SCID | Sirolimus - pharmacology | Proteins - immunology | Endothelial Cells - immunology | Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Promoter Regions, Genetic - immunology | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Ribosomal Protein S6 Kinases - genetics | Index Medicus | Abridged Index Medicus
Journal Article
The journal of clinical endocrinology and metabolism, ISSN 1945-7197, 05/2017, Volume 102, Issue 5, pp. 1468 - 1477
Context: Increasing evidences suggest a correlation between gut and type 1 diabetes (T1D). Objective: The objective of this study is to evaluate the gut... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Receptors, CCR2 - genetics | Serum Amyloid P-Component - immunology | Receptors, CCR2 - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Transcriptome | Child, Preschool | Male | Monocyte Chemoattractant Proteins - immunology | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Interleukin-4 Receptor alpha Subunit - genetics | Young Adult | Celiac Disease - microbiology | Cyclooxygenase 2 - genetics | Intestinal Mucosa - immunology | Diabetes Mellitus, Type 1 - microbiology | Tumor Necrosis Factor-alpha - immunology | Child | Real-Time Polymerase Chain Reaction | Duodenum - immunology | Vascular Endothelial Growth Factor A - immunology | C-Reactive Protein - genetics | Intestinal Mucosa - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Monocyte Chemoattractant Proteins - genetics | Chemokine CCL22 - genetics | Chemokine CCL19 - genetics | Adolescent | RNA, Ribosomal, 16S - genetics | C-Reactive Protein - immunology | Antigens, CD - immunology | Infant | Case-Control Studies | Duodenum - microbiology | Chemokine CCL22 - immunology | Celiac Disease - immunology | Adult | Female | Diabetes Mellitus, Type 1 - immunology | Chemokine CCL19 - immunology | Cyclooxygenase 2 - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Diabetes Mellitus, Type 1 - genetics | Gastrointestinal Microbiome - genetics | Interleukin-4 Receptor alpha Subunit - immunology | Antigens, Differentiation, Myelomonocytic - genetics | Serum Amyloid P-Component - genetics | Aged | Immunohistochemistry | CC chemokine receptors | rRNA 16S | CCL19 protein | Pathogenesis | Mucosa | Microbiomes | Diabetes mellitus (insulin dependent) | Macrophages | Small intestine | Gene sequencing | CCL22 protein | Microbiota | CCR2 protein | Intestine | Interleukin 4 receptors | Digestive tract | Duodenum | Digestive system | Abnormalities | Diabetes mellitus | Inflammation | Tumor necrosis factor-α | Gene expression | Ribonucleic acid--RNA | Disease control | Patients | Celiac disease | Biopsy | Infiltration | Diabetes | Cyclooxygenase-2 | Autoimmune diseases | Monocyte chemoattractant protein 1 | Index Medicus | Abridged Index Medicus
Journal Article
Nature immunology, ISSN 1529-2916, 04/2016, Volume 17, Issue 5, pp. 514 - 522
Cytosolic DNA-mediated activation of the transcription factor IRF3 is a key event in host antiviral responses. Here we found that infection with DNA viruses... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Ovalbumin - immunology | Cytosol - immunology | Dendritic Cells - immunology | Humans | Immunoblotting | Interferon Regulatory Factor-3 - genetics | Herpesvirus 1, Human - physiology | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Bone Marrow Cells - immunology | HEK293 Cells | Adenoviridae - genetics | Herpesvirus 1, Human - immunology | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Adenoviridae - immunology | Dendritic Cells - metabolism | Protein-Serine-Threonine Kinases - metabolism | Interferon Regulatory Factor-3 - immunology | Ovalbumin - genetics | DNA - immunology | Immunization - methods | Membrane Proteins - genetics | Mice, Inbred C57BL | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | DNA - metabolism | Cytosol - virology | Ribosomal Protein S6 Kinases, 90-kDa - immunology | Herpes Simplex - immunology | Mice, Knockout | DNA - genetics | Herpes Simplex - virology | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Cytosol - metabolism | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Transcription factors | Genetic aspects | Regulation | Immune response | Properties | Cellular control mechanisms | Index Medicus | Factors de transcripció | Gene expression | Expressió gènica
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 11/2016, Volume 68, Issue 11, pp. 2646 - 2661
Journal Article
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 10/2019, Volume 14, Issue 10, pp. e0223260 - e0223260
...) using a gene-expression based or an immunohistochemical approach. In this study we aimed to identify additional proteins that are differentially expressed between GCB and non-GCB DLBCL... 
MOLECULAR SUBTYPES | ORIGIN | QUANTITATIVE PROTEOMICS | AMINO-ACIDS | CLASSIFICATION | CULTURE | GLOMULIN | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Germinal Center - immunology | Humans | Middle Aged | Male | Ribosomal Proteins - immunology | Tumor Suppressor Protein p53 - genetics | Adaptor Proteins, Signal Transducing - immunology | Aged, 80 and over | Lymphoma, Large B-Cell, Diffuse - immunology | Adult | Female | B-Lymphocytes - pathology | Proteomics - methods | Child | Gene Expression | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphocyte Activation | Ribosomal Proteins - genetics | Proto-Oncogene Proteins c-myc - immunology | Tumor Suppressor Protein p53 - immunology | Germinal Center - pathology | Lymphoma, Large B-Cell, Diffuse - diagnosis | Isotope Labeling - methods | B-Lymphocytes - immunology | Lymphoma, Large B-Cell, Diffuse - classification | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Cell Line, Tumor | Aged | Biomarkers, Tumor - genetics | Proto-Oncogene Proteins c-myc - genetics | Neoplasm Staging | Biomarkers, Tumor - immunology | Cohort Studies | Immunohistochemistry | Medical research | p53 Protein | Cloning | Biology | Myc protein | Tumor cell lines | Gene expression | Lymphoma | Subgroups | Proteins | Studies | Pathology | Angiogenesis | Algorithms | Lymphocytes B | Proteomics | Classification | Ribosomal protein L23 | Replication | Lymphomas | Hodgkin's disease | B-cell lymphoma | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 06/2017, Volume 546, Issue 7660, pp. 667 - 670
Rotavirus, a leading cause of severe gastroenteritis and diarrhoea in young children, accounts for around 215,000 deaths annually worldwide. Rotavirus... 
Intestines | DEAD-box RNA Helicases | Pyroptosis | Inflammasomes | Rotavirus | Mice, Inbred C57BL | Receptors, G-Protein-Coupled | Male | Epithelial Cells | Immunity, Innate | Journal Article | Research Support, N.I.H., Extramural | Rotavirus Infections | Research Support, U.S. Gov't, Non-P.H.S | Animals | Apoptosis Regulatory Proteins | Research Support, Non-U.S. Gov't | CARD Signaling Adaptor Proteins | Female | Caspase 1 | Mice | RNA, Double-Stranded | Interleukin-18 | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Interleukin-18 - immunology | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Inflammasomes - metabolism | Rotavirus - growth & development | Receptors, G-Protein-Coupled - metabolism | Rotavirus - immunology | Caspase 1 - metabolism | Intestines - immunology | Receptors, G-Protein-Coupled - immunology | CARD Signaling Adaptor Proteins - metabolism | RNA, Double-Stranded - metabolism | Rotavirus Infections - virology | DEAD-box RNA Helicases - metabolism | Inflammasomes - chemistry | Inflammasomes - genetics | Apoptosis Regulatory Proteins - metabolism | Rotavirus Infections - immunology | Receptors, G-Protein-Coupled - deficiency | Epithelial Cells - immunology | Epithelial Cells - virology | Intestines - cytology | Epithelial cells | Health aspects | Rotaviruses | Gastroenteritis | Mucosa | Interleukin | Ribosomal DNA | Viruses | Infections | Small intestine | Caspase-1 | DNA helicase | Proteins | Signal transduction | Rodents | Modulation | Children | Feces | Adaptor proteins | Pathogens | Medical research | Cytokines | Maturation | Double-stranded RNA | Diarrhea | Caspase | Ribonucleic acid--RNA | Signaling | Replication | Fatalities | In vivo methods and tests | Interferon | Viral infections | RNA helicase | Index Medicus
Journal Article
Journal Article