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Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2010, Volume 29, Issue 1, pp. 80 - 92
It is generally assumed that, in Saccharomyces cerevisiae , immature 40S ribosomal subunits are not competent for translation initiation. Here, we show by... 
translation initiation | no go decay | Rio1p | yeast | ribosome biogenesis | Ribosome biogenesis | Yeast | No go decay | Translation initiation | PARTICLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | SMALL NUCLEOLAR RNPS | NUCLEAR EXPORT | BINDING PROTEIN | CLEAVAGE | H/ACA SNORNPS | CELL BIOLOGY | MESSENGER-RNAS | BIOGENESIS | YEAST RIBOSOMES | CYTOPLASMIC MATURATION | DNA, Fungal - genetics | Saccharomyces cerevisiae - genetics | Ribosomes - metabolism | Peptide Chain Initiation, Translational | Polyribosomes - genetics | Saccharomyces cerevisiae - metabolism | Ribosome Subunits, Large, Eukaryotic - metabolism | Base Sequence | Eukaryotic Initiation Factor-3 - genetics | RNA Precursors - metabolism | RNA, Fungal - genetics | Eukaryotic Initiation Factor-1 - metabolism | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Ribosome Subunits, Small, Eukaryotic - genetics | Ribosome Subunits, Large, Eukaryotic - genetics | RNA Processing, Post-Transcriptional | Eukaryotic Initiation Factor-1 - genetics | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | RNA Precursors - genetics | Eukaryotic Initiation Factor-3 - metabolism | Saccharomyces cerevisiae Proteins - genetics | RNA, Fungal - metabolism | Ribosomes - genetics | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Polyribosomes - metabolism | Kinetics | Ribosome Subunits, Small, Eukaryotic - metabolism | Cellular biology | Molecular biology | Ribonucleic acid--RNA | RNA Precursors | Protein-Serine-Threonine Kinases | Biochemistry, Molecular Biology | Ribosome Subunits, Small, Eukaryotic | Ribosomes | Eukaryotic Initiation Factor-1 | DNA, Fungal | Eukaryotic Initiation Factor-3 | Nuclear Proteins | Life Sciences | Saccharomyces cerevisiae Proteins | RNA, Fungal | Ribosome Subunits, Large, Eukaryotic | Polyribosomes | Saccharomyces cerevisiae
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2017, Volume 474, Issue 2, pp. 195 - 214
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 43, pp. 12174 - 12179
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 13, pp. 5046 - 5051
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 45, pp. 15981 - 15986
All organisms have evolved mechanisms to manage the stalling of ribosomes upon translation of aberrant mRNA. In eukaryotes, the large ribosomal... 
Proteins | Datasets | Yeasts | Quality assurance | Messenger RNA | Ubiquitins | Ribosomes | Electron microscopy | Transfer RNA | Tunnels | Tae2/nemf | Protein quality control | Listerin/Ltn1 E3 ubiquitin ligase | Cryo-EM | Translational surveillance | SYSTEM | listerin/Ltn1 E3 ubiquitin ligase | MULTIDISCIPLINARY SCIENCES | ELECTRON-MICROSCOPY | CRYO-EM IMAGES | FREALIGN | Tae2/Nemf | LISTERIN | DISSOCIATION | SCREEN | translational surveillance | protein quality control | SIGNAL RECOGNITION PARTICLE | cryo-EM | E3 UBIQUITIN LIGASE | REVEALS | Protein Structure, Tertiary | Ribosome Subunits, Large, Eukaryotic - genetics | Saccharomyces cerevisiae - genetics | Protein Biosynthesis - physiology | Ubiquitin-Protein Ligases - metabolism | RNA, Transfer, Amino Acyl - genetics | Structure-Activity Relationship | RNA-Binding Proteins | Saccharomyces cerevisiae Proteins - genetics | Saccharomyces cerevisiae - metabolism | Ribosome Subunits, Large, Eukaryotic - metabolism | Proteolysis | RNA, Transfer, Amino Acyl - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Proteasome Endopeptidase Complex - metabolism | Ubiquitination - physiology | Ubiquitin-Protein Ligases - genetics | Genetic research | Genetic aspects | Research | Structure | Genetic translation | Eukaryotes | Surveillance | Microscopy | Ribonucleic acid--RNA | Chemical synthesis | Biological Sciences | Nemf | listerin | Tae2 | Ltn1 E3 ubiquitin ligase
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2016, Volume 291, Issue 23, pp. 12245 - 12253
Protein homeostasis is maintained by quality control mechanisms that detect and eliminate deficient translation products. Cytosolic defective proteins can... 
YEAST | MESSENGER-RNA SURVEILLANCE | DISSOCIATION | QUALITY-CONTROL COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEASOME | DEGRADATION | MISFOLDED PROTEINS | TRANSLATION | TRANSCRIPTION FACTOR | RIBOSOME | Protein Aggregates | RNA-Binding Proteins - genetics | Threonine - chemistry | Saccharomyces cerevisiae - genetics | Valosin Containing Protein | Alanine - chemistry | Threonine - metabolism | Cell Cycle Proteins - chemistry | Saccharomyces cerevisiae - metabolism | Ubiquitination | Ribosome Subunits, Large, Eukaryotic - metabolism | Alanine - genetics | Proteolysis | Threonine - genetics | Cell Cycle Proteins - genetics | Protein Biosynthesis - genetics | Proteomics - methods | Ribosome Subunits, Large, Eukaryotic - genetics | RNA-Binding Proteins - chemistry | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Adenosine Triphosphatases - metabolism | Alanine - metabolism | Saccharomyces cerevisiae Proteins - genetics | Ubiquitin-Protein Ligases - chemistry | Blotting, Western | Saccharomyces cerevisiae Proteins - metabolism | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Mutation | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | Microscopy, Fluorescence | RNA-Binding Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | translation control | Saccharomyces cerevisiae | protein aggregation | protein degradation | ubiquitin | Protein Synthesis and Degradation
Journal Article
RNA, ISSN 1355-8382, 10/2012, Volume 18, Issue 10, pp. 1805 - 1822
Ribosome biogenesis is a complex multistep process that involves alternating steps of folding and processing of pre-rRNAs in concert with assembly of ribosomal... 
Yeast ribosome assembly | Yeast ribosomal proteins L7 and L8 | Polypeptide exit tunnel | 25S rRNA domains I and II | Preribosomes | RNA-Binding Proteins - genetics | Active Transport, Cell Nucleus - physiology | Protein Interaction Domains and Motifs - physiology | Saccharomyces cerevisiae - genetics | Gene Expression Profiling | Saccharomyces cerevisiae - ultrastructure | Ribosomal Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Cell Nucleus - metabolism | Ribosome Subunits, Large, Eukaryotic - metabolism | Microarray Analysis | Protein Interaction Domains and Motifs - genetics | Protein Multimerization - physiology | Protein Multimerization - genetics | RNA Precursors - metabolism | Organisms, Genetically Modified | Active Transport, Cell Nucleus - genetics | Yeasts - metabolism | Gene Expression Regulation, Fungal | Ribosome Subunits, Large, Eukaryotic - genetics | RNA-Binding Proteins - physiology | Ribosomal Proteins - genetics | Ribosome Subunits, Large, Eukaryotic - chemistry | RNA, Ribosomal - chemistry | RNA, Ribosomal - metabolism | RNA Processing, Post-Transcriptional - physiology | Saccharomyces cerevisiae Proteins - genetics | Yeasts - genetics | RNA Processing, Post-Transcriptional - genetics | Cell Nucleus - genetics | Ribosomal Proteins - physiology | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae Proteins - physiology | RNA-Binding Proteins - metabolism | polypeptide exit tunnel | yeast ribosomal proteins L7 and L8 | yeast ribosome assembly | preribosomes
Journal Article