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Nature Structural and Molecular Biology, ISSN 1545-9993, 09/2012, Volume 19, Issue 9, pp. 957 - 963
Journal Article
Journal Article
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2014, Volume 44, Issue 1, pp. 38 - 46
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2018, Volume 62, Issue 5
Journal Article
Journal of Peptide Science, ISSN 1075-2617, 09/2016, Volume 22, Issue 9, pp. 592 - 599
Recent surveillance data on antimicrobial resistance predict the beginning of the post‐antibiotic era with pan‐resistant bacteria even overcoming polymyxin as... 
Gram‐negative bacteria | fluorescence polarization | 70S ribosome | proline‐rich antimicrobial peptides | proline-rich antimicrobial peptides | Gram-negative bacteria | CHEMISTRY, ANALYTICAL | MECHANISM | SBMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | TRANSLATION | PROTEIN-SYNTHESIS | BAC7 | ANTIMICROBIAL PEPTIDE BAC7(1-35) | PROLINE-RICH PEPTIDES | RESISTANCE | Ribosome Subunits, Large, Bacterial - metabolism | Escherichia coli - drug effects | Pseudomonas aeruginosa - growth & development | Antimicrobial Cationic Peptides - metabolism | Microbial Sensitivity Tests | Anti-Bacterial Agents - chemistry | Escherichia coli - growth & development | Binding Sites | Binding, Competitive | Ribosome Subunits, Small, Bacterial - metabolism | Antimicrobial Cationic Peptides - chemistry | Antimicrobial Cationic Peptides - pharmacology | Spectrometry, Fluorescence | Anti-Bacterial Agents - metabolism | Ribosome Subunits, Small, Bacterial - drug effects | Fluoresceins | Pseudomonas aeruginosa - drug effects | Ribosome Subunits, Large, Bacterial - drug effects | Pseudomonas aeruginosa - genetics | Escherichia coli - genetics | Protein Binding | Ethylene Glycol - chemistry | Anti-Bacterial Agents - pharmacology | Kinetics | Fluorescent Dyes | Ethylene glycol | Drug resistance in microorganisms | Peptides | Escherichia coli | Proline | Fluorescence | Bacteria | Chemical properties | Antibacterial agents | Tunnels
Journal Article
Current topics in medicinal chemistry, 2018, Volume 18, Issue 24, p. 2080
The use of antibiotics has revolutionized medicine, greatly improving our capacity to save millions of lives from otherwise deadly bacterial infections.... 
Microbial Sensitivity Tests | Biological Products - chemistry | Bacteria - chemistry | Anti-Bacterial Agents - chemistry | Humans | Bacteria - drug effects | Ribosome Subunits, Small, Bacterial - drug effects | Anti-Bacterial Agents - pharmacology | Biological Products - pharmacology | Drug Discovery
Journal Article
Nucleic acids symposium series (2004), 2007, Issue 51, pp. 375 - 376
RsgA is a unique GTP hydrolytic protein that is widely found in bacteria and plants, and is activated by the small subunit of the ribosome. Disruption of the... 
Escherichia coli Proteins - metabolism | Ribosome Subunits, Small, Bacterial - drug effects | Ribosome Subunits, Small, Bacterial - metabolism | Anti-Bacterial Agents - pharmacology | GTP Phosphohydrolases - metabolism
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2014, Volume 111, Issue 46, pp. 16274 - 16279
Negamycin is a natural product with broad-spectrum antibacterial activity and efficacy in animal models of infection. Although its precise mechanism of action... 
Messenger RNA | Antibiotics | Molecular structure | Protein synthesis | Ribosomes | Crystals | Codons | Inhibitory concentration 50 | Binding sites | Transfer RNA | Fidelity | Antibiotic | Translation | Ribosome | Negamycin | antibiotic | ANTIBIOTICS | AMINOACYL-TRANSFER-RNA | MULTIDISCIPLINARY SCIENCES | COMPLEXES | fidelity | PROTEIN-SYNTHESIS | negamycin | STRUCTURAL BASIS | translation | RESISTANCE | ribosome | TETRACYCLINE | MUTATIONS | TERMINATION | SELECTION | Tetracyclines - metabolism | Tetracycline Resistance - genetics | Minocycline - pharmacology | Escherichia coli - drug effects | Minocycline - analogs & derivatives | Crystallography, X-Ray | Tetracyclines - pharmacology | RNA, Ribosomal, 16S - physiology | RNA, Bacterial - physiology | RNA, Bacterial - genetics | Nucleic Acid Conformation | Binding Sites | Amino Acids, Diamino - pharmacology | Binding, Competitive | RNA, Transfer - metabolism | Models, Molecular | Anti-Bacterial Agents - metabolism | Point Mutation | RNA, Ribosomal, 16S - chemistry | Ribosomes - ultrastructure | RNA, Bacterial - drug effects | Base Pairing | Escherichia coli - genetics | RNA, Bacterial - chemistry | Ribosomes - drug effects | RNA, Ribosomal, 16S - genetics | Protein Biosynthesis - drug effects | Anti-Bacterial Agents - pharmacology | Drug Resistance, Multiple, Bacterial - genetics | RNA, Ribosomal, 16S - drug effects | Microbiological research | Escherichia coli | Genetic research | Genetic aspects | Research | Genetic translation | Binding sites (Biochemistry) | Fluorescence | Molecules | E coli | Ribonucleic acid--RNA | Crystal structure | Biological Sciences | Physical Sciences
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2018, Volume 70, Issue 1, pp. 83 - 94.e7
Journal Article