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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 03/2014, Volume 58, Issue 3, pp. 1757 - 1762
Journal Article
Lancet Infectious Diseases, The, ISSN 1473-3099, 2013, Volume 13, Issue 1, pp. 27 - 35
Summary Background Intensified antibiotic treatment might improve the outcome of tuberculous meningitis. We assessed pharmacokinetics, safety, and survival... 
Infectious Disease | MYCOBACTERIUM-TUBERCULOSIS | ETHAMBUTOL | INFECTIOUS DISEASES | IN-VITRO | PHARMACOKINETICS | LEVOFLOXACIN | PULMONARY TUBERCULOSIS | INFECTION | DRUG-RESISTANCE | CEREBROSPINAL-FLUID | CIPROFLOXACIN | Fluoroquinolones | Aza Compounds - pharmacokinetics | Antitubercular Agents - adverse effects | Rifampin - pharmacokinetics | Antibiotics, Antitubercular - adverse effects | Follow-Up Studies | Humans | Middle Aged | Aza Compounds - adverse effects | Male | Quinolines - administration & dosage | Quinolines - pharmacokinetics | Young Adult | Drug Therapy, Combination - adverse effects | Rifampin - adverse effects | Adult | Female | Rifampin - administration & dosage | Antibiotics, Antitubercular - administration & dosage | Aza Compounds - administration & dosage | Anti-Infective Agents - adverse effects | Antibiotics, Antitubercular - pharmacokinetics | Tuberculosis, Meningeal - drug therapy | Drug Administration Schedule | Drug Therapy, Combination - methods | Anti-Infective Agents - administration & dosage | Antitubercular Agents - pharmacokinetics | Anti-Infective Agents - pharmacokinetics | Adolescent | Antitubercular Agents - administration & dosage | Tuberculosis, Meningeal - metabolism | Quinolines - adverse effects | Indonesia | Tuberculosis | Meningitis | Dosage and administration | Product development | Moxifloxacin | Universities and colleges | Rifampin | Index Medicus
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2015, Volume 191, Issue 1, pp. 96 - 103
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2011, Volume 365, Issue 23, pp. 2155 - 2166
Journal Article
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 06/2018, Volume 84, Issue 6, pp. 1156 - 1169
AimsWe investigated the effects of a strong CYP3A4 inhibitor (itraconazole) or inducer (rifampicin) on the pharmacokinetics of the epidermal growth factor... 
clinical pharmacology, drug metabolism | drug information | drug interactions | pharmacokinetics, biomarkers | drug analysis, lung cancer | oncology | 1ST-LINE TREATMENT | SYSTEMIC ANTIMYCOTICS KETOCONAZOLE | drug analysis | biomarkers | PHASE-III | ACQUIRED-RESISTANCE | T790M MUTATION | OPEN-LABEL | EGFR MUTATIONS | DRUG-DRUG INTERACTION | lung cancer | CELL LUNG-CANCER | GROWTH-FACTOR RECEPTOR | drug metabolism | pharmacokinetics | clinical pharmacology | PHARMACOLOGY & PHARMACY | Piperazines - administration & dosage | Lung Neoplasms - drug therapy | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Cytochrome P-450 CYP3A Inducers - adverse effects | Rifampin - adverse effects | Drug Interactions | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Itraconazole - administration & dosage | Antineoplastic Agents - pharmacokinetics | Piperazines - pharmacokinetics | Rifampin - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | Protein Kinase Inhibitors - pharmacokinetics | Cytochrome P-450 CYP3A Inhibitors - administration & dosage | Drug Administration Schedule | Risk Assessment | Administration, Oral | Risk Factors | Treatment Outcome | Piperazines - adverse effects | Cytochrome P-450 CYP3A Inducers - administration & dosage | Protein Kinase Inhibitors - administration & dosage | Itraconazole - adverse effects | Models, Biological | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Cytochrome P-450 CYP3A Inhibitors - adverse effects | Tyrosine | Medical research | Epidermal growth factor | Analysis | Cytochrome P-450 | Physiological aspects | Medicine, Experimental | Lung cancer, Non-small cell | Rifampin | Itraconazole | Index Medicus | Original
Journal Article
PLoS Medicine, ISSN 1549-1277, 12/2007, Volume 4, Issue 12, pp. 1931 - 1939
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2012, Volume 56, Issue 6, pp. 3027 - 3031
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2017, Volume 83, Issue 12, pp. 2778 - 2788
AimsBased on in vitro data, there is evidence to suggest that cytochrome P450 (CYP) 2C8 is involved in the metabolism of selexipag and its active metabolite,... 
pharmacokinetics | rifampicin | selexipag | CYP2C8 | drug interactions | gemfibrozil | PULMONARY ARTERIAL-HYPERTENSION | TREPROSTINIL | REPAGLINIDE | CLOPIDOGREL | CONCISE GUIDE | PHARMACOLOGY | TOLERABILITY | PROSTACYCLIN RECEPTOR AGONIST | PHARMACOLOGY & PHARMACY | INHIBITOR | Prodrugs - administration & dosage | Activation, Metabolic | Cytochrome P-450 CYP2C8 Inhibitors - administration & dosage | Acetates - adverse effects | Acetates - blood | Area Under Curve | Humans | Middle Aged | Pyrazines - administration & dosage | Antihypertensive Agents - administration & dosage | Half-Life | Male | Metabolic Clearance Rate | Gemfibrozil - adverse effects | Healthy Volunteers | Acetamides - blood | Young Adult | Rifampin - adverse effects | Drug Interactions | Acetamides - adverse effects | Cytochrome P-450 CYP2C8 Inducers - adverse effects | Adult | Cytochrome P-450 CYP2C8 - metabolism | Rifampin - administration & dosage | Gemfibrozil - administration & dosage | Cytochrome P-450 CYP2C8 Inducers - administration & dosage | Acetamides - pharmacokinetics | Risk Assessment | Cytochrome P-450 CYP2C8 Inhibitors - adverse effects | Antihypertensive Agents - pharmacokinetics | Antihypertensive Agents - adverse effects | Antihypertensive Agents - blood | Cross-Over Studies | Prodrugs - adverse effects | Acetates - administration & dosage | Prodrugs - pharmacokinetics | Pyrazines - pharmacokinetics | Adolescent | Pyrazines - adverse effects | Pyrazines - blood | Germany | Acetamides - administration & dosage | Acetates - pharmacokinetics | Metabolites | Gemfibrozil | Cytochrome P-450 | Nausea | Drug therapy, Combination | Rifampin | Fibric acids | Index Medicus
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2006, Volume 29, Issue 1, pp. 51 - 55
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2012, Volume 56, Issue 6, pp. 3114 - 3120
Journal Article