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Journal Article
BMB Reports, ISSN 1976-6696, 2018, Volume 51, Issue 10, pp. 484 - 485
Receptor-interacting protein kinase-3 (RIP3 or RIPK3) is a serine-threonine kinase largely essential for necroptotic cell death; it also plays a role in some... 
PELI1 | RIP3 | TEN | Necroptosis | Proteasome
Journal Article
FASEB Journal, ISSN 0892-6638, 01/2019, Volume 33, Issue 1, pp. 942 - 952
The role for the NOD-like receptor (NLR) P3 inflammasome in enterovirus infection remains controversial. Available data suggest that the NLRP3 inflammasome is... 
Coxsackievirus | Inflammasome | Innate immune response | RIP1/RIP3 | PROTEIN | COXSACKIEVIRUS B3 INFECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | coxsackievirus | INNATE | NONCANONICAL INFLAMMASOME ACTIVATION | CLEAVAGE | CELL BIOLOGY | MAVS | INTERLEUKIN-18 | innate immune response | inflammasome | BIOLOGY | RIP3 | RIP1
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 13, pp. E2786 - E2795
The complex interplay between caspase-8 and receptor-interacting protein (RIP) kinase RIP 3 (RIPK3) driving extrinsic apoptosis and necroptosis is not fully... 
Caspase-8 | Inflammation | RIP3 kinase | MCMV | Cell death | APOPTOSIS | caspase-8 | NECROPTOSIS | PROTEIN | VIRUS | cell death | MULTIDISCIPLINARY SCIENCES | CASPASE-8 ACTIVATION | NECROSIS | INHIBITION | inflammation | HOST-DEFENSE | RIP3 | NF-KAPPA-B | Cytomegaloviruses | Health aspects | Biological Sciences | PNAS Plus
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 26, pp. 3637 - 3640
We report the development of novel Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitors with single nanomolar potency (compound 15 is also named as... 
ACTIVATION | NECROSIS | MLKL | INFLAMMATION | RIP3 | CHEMISTRY, MULTIDISCIPLINARY | CELL-DEATH
Journal Article
Journal of Plastic, Reconstructive & Aesthetic Surgery, ISSN 1748-6815, 10/2019, Volume 72, Issue 10, pp. 1661 - 1668
Hydrogen gas exists in the atmosphere and was previously considered an inert gas. It has been reported to have protective effects on tissue... 
Ischemia-reperfusion injury | RIP3 | Skin flap | Hydrogen | RIP1
Journal Article
Circulation Research, ISSN 0009-7330, 02/2015, Volume 116, Issue 4, pp. 600 - 611
RATIONALE:Depletion of medial smooth muscle cell (SMC) is a major pathological characteristic of abdominal aortic aneurysm (AAA), although the mechanism by... 
Mouse | Protein kinase C-delta | Smooth muscle | Myocytes | Abdominal | Aortic aneurysm | Apoptosis | Necrosis | Nuclear factor kappa B | Rip3 protein | ARTERIAL INJURY | myocytes, smooth muscle | CARDIAC & CARDIOVASCULAR SYSTEMS | NECROPTOSIS | C-DELTA | aortic aneurysm, abdominal | nuclear factor kappa B | PROGRAMMED NECROSIS | BINDING-PROTEIN | apoptosis | DEATH | MODEL | protein kinase C-delta | necrosis | Rip3 protein, mouse | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | HEMATOLOGY | NF-KAPPA-B | Inflammation - chemically induced | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Aortic Aneurysm, Abdominal - chemically induced | Aortic Aneurysm, Abdominal - prevention & control | Humans | Tumor Necrosis Factor-alpha - genetics | Aorta, Abdominal - transplantation | Myocytes, Smooth Muscle - pathology | Transfection | RNA Interference | Inflammation Mediators - metabolism | Aorta, Abdominal - pathology | Myocytes, Smooth Muscle - transplantation | Aortic Aneurysm, Abdominal - pathology | Disease Models, Animal | Myocytes, Smooth Muscle - enzymology | Mice, Inbred C57BL | Cells, Cultured | Aortic Aneurysm, Abdominal - genetics | Muscle, Smooth, Vascular - transplantation | Aorta, Abdominal - enzymology | Mice, Knockout | Protein Kinase C-delta - metabolism | Muscle, Smooth, Vascular - pathology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Aortic Aneurysm, Abdominal - enzymology | Transcription Factor RelA - metabolism | Inflammation - genetics | Pancreatic Elastase | Inflammation - prevention & control | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Inflammation - enzymology | Muscle, Smooth, Vascular - enzymology | Protein Kinase C-delta - genetics | smooth muscle cells | Protein Kinase C [delta] | Abdominal aortic aneurysm | nuclear factor-kappa B | RIP3 | necroptosis
Journal Article
HEPATOLOGY, ISSN 0270-9139, 11/2016, Volume 64, Issue 5, pp. 1518 - 1533
Multiple pathways of programmed cell death are important in liver homeostasis. Hepatocyte death is associated with progression of nonalcoholic fatty liver... 
APOPTOSIS | NECROPTOSIS | LIVER-INJURY | KINASE 3 | PROGRAMMED NECROSIS | ANIMAL-MODELS | NONALCOHOLIC STEATOHEPATITIS | RIP3 | GASTROENTEROLOGY & HEPATOLOGY | CELL-DEATH | HEPATOCARCINOGENESIS
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2014, Volume 127, Issue 10, pp. 2135 - 2144
Regulated, programmed cell death is crucial for all multicellular organisms. Cell death is essential in many processes, including tissue sculpting during... 
Mitochondria | Pyroptosis | MLKL | RIPK3 | Necroptosis | DOMAIN-LIKE PROTEIN | MIXED LINEAGE KINASE | PROGRAMMED NECROSIS | CASPASE 8 | MOLECULAR SWITCH | AUTOPHAGY | TNF | CELL BIOLOGY | CYTOCHROME-C | TUMOR-NECROSIS-FACTOR | RIP3 | Autophagy - physiology | Animals | Apoptosis - physiology | Cell Death - physiology | Humans
Journal Article
Journal Article
Theranostics, ISSN 1838-7640, 2019, Volume 9, Issue 12, pp. 3659 - 3673
Necroptosis is a programmed form of non-apoptotic cell death that requires receptor-interacting protein 3 (RIP3). RIP3 has been shown to be relevant in... 
Journal Article
EMBO reports, ISSN 1469-221X, 02/2019, Volume 20, Issue 2, p. n/a
Functional amyloids have recently attracted much attention due to their involvement in signalling pathways, with hybrid amyloid formation showcasing a key role... 
FORMS | RIP3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Proteins | Signal transduction | Therapeutic applications | Assembly | Mimicry
Journal Article
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 10/2018, Volume 138, Issue 10, pp. e59 - e63
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2016, Volume 26, Issue 9, pp. 1021 - 1032
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 11/2014, Volume 35, pp. 14 - 23
Journal Article