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Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 08/2010, Volume 104, Issue 2, pp. 302 - 310
Journal Article
Seminars in Hematology, ISSN 0037-1963, 2014, Volume 51, Issue 2, pp. 89 - 97
The direct thrombin inhibitor, dabigatran, as well as the direct factor Xa inhibtors rivaroxaban, apixaban, and edoxaban, display pharmacodynamic features... 
IN-VITRO | FACTOR-XA INHIBITOR | DIRECT THROMBIN INHIBITOR | DABIGATRAN ETEXILATE | VENOUS THROMBOEMBOLISM | RIVAROXABAN BAY 59-7939 | DEEP-VEIN THROMBOSIS | HEALTHY-VOLUNTEERS | HEMATOLOGY | RENAL IMPAIRMENT | ATRIAL-FIBRILLATION | Thiazoles - blood | Anticoagulants - administration & dosage | beta-Alanine - blood | Humans | beta-Alanine - pharmacokinetics | Half-Life | Pyridines - pharmacokinetics | Thiazoles - administration & dosage | Thiophenes - administration & dosage | Dabigatran | Morpholines - blood | Thiophenes - blood | Pyridones - blood | Thiazoles - pharmacokinetics | Pyridones - administration & dosage | Rivaroxaban | Kidney - metabolism | Drug Interactions | Benzimidazoles - administration & dosage | Thromboembolism - prevention & control | Pyrazoles - blood | Hemorrhage - etiology | Thromboembolism - drug therapy | Pyrazoles - pharmacokinetics | beta-Alanine - analogs & derivatives | Benzimidazoles - blood | Pyridines - administration & dosage | Pyridones - pharmacokinetics | Administration, Oral | Morpholines - administration & dosage | beta-Alanine - administration & dosage | Benzimidazoles - pharmacokinetics | Anticoagulants - adverse effects | Thiophenes - pharmacokinetics | Pyrazoles - administration & dosage | Pyridines - blood | Anticoagulants - pharmacokinetics | Morpholines - pharmacokinetics | Drug Monitoring
Journal Article
Journal Article
BRITISH JOURNAL OF HAEMATOLOGY, ISSN 0007-1048, 12/2013, Volume 163, Issue 5, pp. 666 - 673
There is increasing recognition that thrombotic complications may occur in patients with cirrhosis, and literature on antithrombotic treatment in these... 
anticoagulants | antithrombin | coagulation | anti‐Xa assay | cirrhosis | Anti-Xa assay | Anticoagulants | Cirrhosis | Antithrombin | Coagulation | anti-Xa assay | THROMBOSIS | MOLECULAR-WEIGHT HEPARIN | LIVER-DISEASE | HEMATOLOGY | HEMOSTASIS | Thiophenes - therapeutic use | Heparin, Low-Molecular-Weight - pharmacology | Polysaccharides - blood | Factor Xa Inhibitors | beta-Alanine - blood | Humans | Middle Aged | Heparin - therapeutic use | Male | Dabigatran | Drug Monitoring - methods | Morpholines - blood | Heparin, Low-Molecular-Weight - therapeutic use | Thiophenes - blood | Thrombophilia - etiology | Antithrombins - pharmacology | Rivaroxaban | Heparin, Low-Molecular-Weight - blood | Sensitivity and Specificity | beta-Alanine - pharmacology | Prothrombin - antagonists & inhibitors | Female | beta-Alanine - analogs & derivatives | Benzimidazoles - blood | Heparin - pharmacology | Morpholines - therapeutic use | Benzimidazoles - therapeutic use | Polysaccharides - therapeutic use | Liver Cirrhosis - drug therapy | Liver Cirrhosis - complications | beta-Alanine - therapeutic use | False Negative Reactions | Morpholines - pharmacology | Thiophenes - pharmacology | Liver Cirrhosis - blood | Polysaccharides - pharmacology | Anticoagulants - blood | Diagnostic Tests, Routine | Blood Coagulation - drug effects | Thrombophilia - blood | Anticoagulants - pharmacology | Antithrombins - blood | Blood Coagulation Tests | Heparin - blood | Benzimidazoles - pharmacology | Liver cirrhosis | Anticoagulants (Medicine) | Index Medicus
Journal Article
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, ISSN 1555-9041, 02/2019, Volume 14, Issue 2, pp. 278 - 287
Journal Article
European Journal of Cardio-Thoracic Surgery, ISSN 1010-7940, 04/2017, Volume 51, Issue 4, pp. 624 - 632
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e86491 - e86491
Dabigatran and rivaroxaban are novel oral anticoagulants that specifically inhibit thrombin and factor Xa, respectively. The aim of this study is to elucidate... 
PHASE-II TRIAL | ACTIVATION | DABIGATRAN | ANTICOAGULANTS | PLATELETS | MULTIDISCIPLINARY SCIENCES | RIVAROXABAN | DOUBLE-BLIND | ACUTE CORONARY SYNDROMES | GENERATION | COMBINATION | Factor Xa Inhibitors | Humans | Thrombin - antagonists & inhibitors | Male | Dabigatran | Adenosine Triphosphate - pharmacology | Antithrombins - pharmacology | Dose-Response Relationship, Drug | Rivaroxaban | beta-Alanine - pharmacology | Platelet Aggregation Inhibitors - pharmacology | Purinergic P2 Receptor Antagonists - pharmacology | Adult | Female | Aspirin - pharmacology | Thrombosis - blood | beta-Alanine - analogs & derivatives | Morpholines - pharmacology | Thiophenes - pharmacology | Lab-On-A-Chip Devices | Adenosine Triphosphate - analogs & derivatives | Factor Xa - metabolism | Microscopy, Confocal | Blood Platelets - metabolism | Anticoagulants - pharmacology | Benzimidazoles - pharmacology | Thrombosis - drug therapy | Thrombin - metabolism | Thromboplastin - metabolism | Fibrin - metabolism | Integrated circuits | Fibrin | Aspirin | Collagen | Thrombin | Anticoagulants (Medicine) | Comparative analysis | Thrombosis | Blood clot | Semiconductor chips | Anticoagulants | Cardiac arrhythmia | Stroke | Automation | Shear | Lag time | Biology | Flow | Blood clots | Thromboplastin | Blood platelets | Platelets | Index Medicus
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 10/2011, Volume 50, Issue 10, pp. 675 - 686
Background and Objective: Rivaroxaban is an oral, direct Factor Xa inhibitor, which is at an advanced stage of clinical development for prevention and... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Dose-prediction | Rivaroxaban | Pharmacodynamic-modelling | Atrial-fibrillation | Deep-vein-thrombosis | Population- pharmacokinetics | Factor-Xa-inhibitors | Antithrombotics | Pharmacology | Pharmacokinetic-pharmacodynamic-relationships | Pharmacokinetic-modelling | ENOXAPARIN | IN-VITRO | FACTOR-XA INHIBITOR | BAY-59-7939 | MANAGEMENT | VENOUS THROMBOEMBOLISM | METABOLISM | ARTHROPLASTY | PHARMACOLOGY & PHARMACY | PHARMACODYNAMICS | THROMBOPROPHYLAXIS | Body Weight | Age Factors | Anticoagulants - administration & dosage | Factor Xa Inhibitors | Humans | Middle Aged | Venous Thrombosis - blood | Male | Thiophenes - administration & dosage | Morpholines - blood | Thiophenes - blood | Young Adult | Computer Simulation | Aged, 80 and over | Adult | Female | Acute Disease | Stroke - prevention & control | Venous Thrombosis - drug therapy | Administration, Oral | Atrial Fibrillation - drug therapy | Morpholines - administration & dosage | Morpholines - pharmacology | Thiophenes - pharmacology | Anticoagulants - blood | Atrial Fibrillation - blood | Stroke - blood | Thiophenes - pharmacokinetics | Models, Biological | Anticoagulants - pharmacology | Adolescent | Aged | Anticoagulants - pharmacokinetics | Morpholines - pharmacokinetics | Index Medicus
Journal Article
Journal Article
Internal and Emergency Medicine, ISSN 1828-0447, 4/2017, Volume 12, Issue 3, pp. 387 - 406
The direct oral anticoagulants (DOACs) are drugs used in clinical practice since 2009 for the prevention of stroke or systemic embolism in non-valvular atrial... 
Pulmonary embolism | Internist | Medicine & Public Health | Direct oral anticoagulant | Atrial fibrillation | Drug interactions | Novel oral anticoagulant | Internal Medicine | Venous thrombosis | Elderly | Venous thromboembolism | PERIOPERATIVE MANAGEMENT | FACTOR-XA INHIBITORS | RIVAROXABAN | ATRIAL-FIBRILLATION | MEDICINE, GENERAL & INTERNAL | IN-VITRO | DABIGATRAN | LABORATORY MEASUREMENT | ASSOCIATION PRACTICAL GUIDE | DIRECT ORAL ANTICOAGULANTS | Pyrazoles - therapeutic use | Humans | Internal Medicine - methods | Thiazoles - therapeutic use | Dabigatran - therapeutic use | Antithrombins - pharmacology | Venous Thromboembolism - prevention & control | Time Factors | Drug-Related Side Effects and Adverse Reactions | Liver Diseases - etiology | Clinical Competence - standards | Rivaroxaban - therapeutic use | Pyrazoles - pharmacology | Pyridines - therapeutic use | Dabigatran - pharmacology | Administration, Oral | Atrial Fibrillation - drug therapy | Antithrombins - therapeutic use | Food-Drug Interactions | Anticoagulants - therapeutic use | Stroke - drug therapy | Anticoagulants - adverse effects | Consensus | Factor Xa Inhibitors - therapeutic use | Anticoagulants - pharmacology | Perioperative Period - methods | Italy | Pyridines - pharmacology | Pyridones - therapeutic use | Thiazoles - pharmacology | Rivaroxaban - pharmacology | Pyridones - pharmacology | Thrombin | Usage | Anticoagulants (Medicine) | Index Medicus
Journal Article