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1. Full Text Virological testing of cerebrospinal fluid in children aged less than 14 years with a suspected central nervous system infection: A retrospective study on 304 consecutive children from January 2012 to May 2015
by Parisi, Saverio G and Basso, Monica and Del Vecchio, Claudia and Andreis, Samantha and Franchin, Elisa and Bello, Federico Dal and Pagni, Silvana and Biasolo, Maria Angela and Manganelli, Riccardo and Barzon, Luisa and Palù, Giorgio
European Journal of Paediatric Neurology, ISSN 1090-3798, 07/2016, Volume 20, Issue 4, pp. 588 - 596
The study aimed to describe the prevalence of HSV DNA, VZV DNA, Enterovirus RNA, Parechovirus RNA, CMV DNA, EBV DNA, adenovirus DNA, HHV-6 DNA, HHV-7 DNA,... 
HHV-7 | CSF | In house real time PCR | HUMAN PARECHOVIRUS | CLINICAL CHARACTERISTICS | CLINICAL NEUROLOGY | ENTEROVIRUS | HERPES-SIMPLEX-VIRUS | POLYMERASE-CHAIN-REACTION | ENCEPHALITIS | DNA | PEDIATRICS | HHV-7 INFECTION | EPSTEIN-BARR-VIRUS | PCR ASSAY | Herpesvirus 4, Human - genetics | Prevalence | Picornaviridae Infections - cerebrospinal fluid | Humans | Child, Preschool | Male | Virus Diseases - virology | Herpes Simplex - genetics | Roseolovirus Infections - epidemiology | Enterovirus Infections - epidemiology | Enterovirus - genetics | Picornaviridae Infections - epidemiology | Roseolovirus Infections - cerebrospinal fluid | Child | Real-Time Polymerase Chain Reaction | Epstein-Barr Virus Infections - cerebrospinal fluid | Infant, Newborn | Encephalitis, Varicella Zoster - cerebrospinal fluid | Parvoviridae Infections - epidemiology | Cytomegalovirus - genetics | Cytomegalovirus Infections - cerebrospinal fluid | Central Nervous System Infections - cerebrospinal fluid | Central Nervous System Infections - epidemiology | Herpesvirus 3, Human - genetics | Parvovirus B19, Human - genetics | DNA, Viral - cerebrospinal fluid | Italy - epidemiology | Parvoviridae Infections - cerebrospinal fluid | Herpesviridae Infections - epidemiology | Herpesvirus 7, Human - genetics | Virus Diseases - epidemiology | Cytomegalovirus Infections - epidemiology | Encephalitis, Herpes Simplex - epidemiology | Virus Diseases - cerebrospinal fluid | Adenoviridae Infections - epidemiology | Adenoviridae - genetics | Female | Retrospective Studies | Adenoviridae Infections - cerebrospinal fluid | Epstein-Barr Virus Infections - epidemiology | Herpesviridae Infections - cerebrospinal fluid | Encephalitis, Herpes Simplex - cerebrospinal fluid | Parechovirus - genetics | Herpesvirus 8, Human - genetics | Herpesvirus 6, Human - genetics | Central Nervous System Infections - virology | Enterovirus Infections - cerebrospinal fluid | RNA, Viral - cerebrospinal fluid | Encephalitis, Varicella Zoster - epidemiology | Virus diseases | Medical research | RNA | Adenoviruses | Central nervous system | Medicine, Experimental | Health aspects
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2. Full Text Delayed primary HHV-7 infection and neurologic disease
by Schwartz, Kevin L and Richardson, Susan E and Ward, Katherine N and Donaldson, Callum and MacGregor, Daune and Banwell, Brenda and Mahant, Sanjay and Bitnun, Ari
Pediatrics, ISSN 0031-4005, 06/2014, Volume 133, Issue 6, pp. e1541 - e1547
BACKGROUND: Primary human herpesvirus 7 (HHV-7) infection occurs almost universally during the first 5 years of life and is rarely accompanied by central... 
HHV-7 | Encephalitis | CNS | Meningitis | Child | Guillain-Barré syndrome | IMMUNOCOMPETENT | VIRUS | meningitis | HUMAN-HERPESVIRUS 7 | Guillain-Barr, syndrome | ANTIBODY | PREVALENCE | ACUTE CHILDHOOD ENCEPHALITIS | CHILDREN | encephalitis | AND-7 | PEDIATRICS | child | AGE | Herpesvirus 7, Human - genetics | Predictive Value of Tests | Age Factors | Cross-Sectional Studies | Meningitis, Viral - diagnosis | Humans | Risk Factors | Roseolovirus Infections - diagnosis | Meningitis, Viral - epidemiology | Central Nervous System Infections - diagnosis | Central Nervous System Infections - epidemiology | DNA, Viral - cerebrospinal fluid | Encephalitis, Viral - diagnosis | Roseolovirus Infections - epidemiology | Herpesvirus 7, Human - pathogenicity | Guillain-Barre Syndrome - diagnosis | Guillain-Barre Syndrome - epidemiology | Polymerase Chain Reaction | Ontario | Encephalitis, Viral - epidemiology | Complications and side effects | Nervous system diseases | Care and treatment | Human herpesvirus 7 | Physiological aspects | Febrile convulsions | Research | Risk factors | Polymerase chain reaction | Pediatrics | Herpes viruses | Neurological disorders | Deoxyribonucleic acid--DNA | Fluid
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3. Full Text Classification of HHV-6A and HHV-6B as distinct viruses
by Ablashi, Dharam and Ablashi, Dharam and Agut, Henri and Agut, Henri and Alvarez-Lafuente, Roberto and Alvarez-Lafuente, Roberto and Clark, Duncan A and Clark, Duncan A and Dewhurst, Stephen and Dewhurst, Stephen and DiLuca, Dario and DiLuca, Dario and Flamand, Louis and Flamand, Louis and Frenkel, Niza and Frenkel, Niza and Gallo, Robert and Gallo, Robert and Gompels, Ursula A and Gompels, Ursula A and Höllsberg, Per and Höllsberg, Per and Jacobson, Steven and Jacobson, Steven and Luppi, Mario and Luppi, Mario and Lusso, Paolo and Lusso, Paolo and Malnati, Mauro and Malnati, Mauro and Medveczky, Peter and Medveczky, Peter and Mori, Yasuko and Mori, Yasuko and Pellett, Philip E and Pellett, Philip E and Pritchett, Joshua C and Pritchett, Joshua C and Yamanishi, Koichi and Yamanishi, Koichi and Yoshikawa, Tetsushi and Yoshikawa, Tetsushi
Archives of Virology, ISSN 0304-8608, 5/2014, Volume 159, Issue 5, pp. 863 - 870
Shortly after the discovery of human herpesvirus 6 (HHV-6), two distinct variants, HHV-6A and HHV-6B, were identified. In 2012, the International Committee on... 
Medical Microbiology | Infectious Diseases | Biomedicine | Virology | REAL-TIME PCR | MULTIPLE-SCLEROSIS PATIENTS | POLYMERASE-CHAIN-REACTION | VIROLOGY | CHEMOKINE AGONIST | HUMAN-HERPESVIRUS 6 | CELLULAR RECEPTOR | HUMAN-HERPESVIRUS-6 VARIANT-A | GLYCOPROTEIN-H | MESSENGER-RNA LEVELS | NEUTRALIZING EPITOPE | Genetic Variation | Roseolovirus Infections - epidemiology | Humans | Herpesvirus 6, Human - classification | Roseolovirus Infections - immunology | Roseolovirus Infections - virology | Herpesvirus 6, Human - genetics | Virus diseases | Health aspects
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4. Full Text Human herpesvirus 6 and 7 in febrile status epilepticus: The FEBSTAT study
by Epstein, Leon G and Shinnar, Shlomo and Hesdorffer, Dale C and Nordli, Douglas R and Hamidullah, Aaliyah and Benn, Emma K. T and Pellock, John M and Frank, L. Matthew and Lewis, Darrell V and Moshe, Solomon L and Shinnar, Ruth C and Sun, Shumei and FEBSTAT Study Team and FEBSTAT study team
Epilepsia, ISSN 0013-9580, 09/2012, Volume 53, Issue 9, pp. 1481 - 1488
Summary Purpose:  In a prospective study, Consequences of Prolonged Febrile Seizures in Childhood (FEBSTAT), we determined the frequency of human herpesvirus... 
Febrile seizures | Mesial temporal sclerosis | Human herpesvirus | Status epilepticus | POPULATION | TEMPORAL-LOBE EPILEPSY | CONVULSIVE STATUS EPILEPTICUS | VARIANT-B | IDENTIFICATION | CHILDHOOD | CLINICAL NEUROLOGY | CHILDREN | HUMAN-HERPESVIRUS-6 | SEIZURES | INFECTION | Seizures, Febrile - diagnosis | Prospective Studies | Humans | Child, Preschool | Roseolovirus Infections - diagnosis | Infant | Male | Status Epilepticus - diagnosis | Roseolovirus Infections - epidemiology | Seizures, Febrile - virology | Female | Status Epilepticus - epidemiology | Status Epilepticus - virology | Herpesvirus 7, Human - isolation & purification | Seizures, Febrile - epidemiology | Herpesvirus 6, Human - isolation & purification | Infant, Newborn | Antigen-antibody reactions | Viral antibodies | Medical colleges | Neurosciences | RNA | Comorbidity | DNA | Antibodies | Seizures (Medicine) | Biometry | Medical research | Epilepsy | Infections | Temporal lobe | Viremia | EEG | imaging | Fever | Infection | Polymerase chain reaction | Children | Age | Hippocampus | Injuries | Seizures | Mesial Temporal Sclerosis | Human Herpesvirus | Febrile Seizures | Status Epilepticus
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5. Full Text Prevalence and risk factors for betaherpesvirus DNAemia in children >3 weeks and <2 years of age admitted to a large referral hospital in sub-Saharan Africa
by Tembo, John and Kabwe, Mwila and Chilukutu, Lophina and Chilufya, Moses and Mwaanza, Nyaxewo and Chabala, Chishala and Zumla, Alimuddin and Bates, Matthew
Clinical Infectious Diseases, ISSN 1058-4838, 02/2015, Volume 60, Issue 3, pp. 423 - 431
Background. Betaherpesviruses are established causes of morbidity and mortality in immunosuppressed patient groups but have been little studied in sub-Saharan... 
malnutrition | HIV | CMV | HHV-6 | meningitis | INFECTIOUS DISEASES | VIRUS | HUMAN-HERPESVIRUS 6 | QUANTITATION | HHV-6 DNA | MICROBIOLOGY | IMMUNOLOGY | CEREBROSPINAL-FLUID | BIRTH PREVALENCE | INFANTS | CONGENITAL CYTOMEGALOVIRUS-INFECTION | PROGRESSION | Herpesvirus 7, Human - genetics | Prevalence | Cytomegalovirus Infections - epidemiology | Humans | Child, Preschool | Infant | Male | Thinness | Viral Load | Roseolovirus Infections - epidemiology | Hospitals, Teaching | Cytomegalovirus Infections - etiology | Cytomegalovirus Infections - virology | Female | Herpesvirus 6, Human - isolation & purification | Infant, Newborn | Cytomegalovirus - genetics | Cytomegalovirus - isolation & purification | Risk Factors | Hospitals, University | Herpesvirus 6, Human - genetics | Zambia | DNA, Viral - blood | HIV Infections - complications | Roseolovirus Infections - etiology | Roseolovirus Infections - virology | Herpesvirus 7, Human - isolation & purification | Referral and Consultation | Immunocompromised Host | Patient outcomes | Herpesvirus diseases | Analysis | Herpes | Children | Health aspects | Risk factors | Prevalence studies (Epidemiology)
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6. Full Text A Population-Based Study of Primary Human Herpesvirus 6 Infection
by Zerr, Danielle M and Meier, Amalia S and Selke, Stacy S and Frenkel, Lisa M and Huang, Meei-Li and Wald, Anna and Rhoads, Margaret P and Nguy, Long and Bornemann, Rena and Morrow, Rhoda Ashley and Corey, Lawrence
The New England Journal of Medicine, ISSN 0028-4793, 02/2005, Volume 352, Issue 8, pp. 768 - 776
In this study of serial saliva specimens from 277 children, 40 percent were infected with human herpesvirus 6 (HHV-6) by 12 months of age and 77 percent were... 
MEDICINE, GENERAL & INTERNAL | HUMAN HERPESVIRUS-6 INFECTION | REACTIVATION | DNA | CHILDREN | Exanthema Subitum - epidemiology | Prospective Studies | Immunoglobulin G - blood | Humans | Child, Preschool | Roseolovirus Infections - diagnosis | DNA, Viral - analysis | Infant | Male | Antibodies, Viral - blood | Incidence | Roseolovirus Infections - epidemiology | Herpesvirus 6, Human - immunology | Polymerase Chain Reaction | Female | Herpesvirus 6, Human - isolation & purification | Infant, Newborn | Risk Factors | Proportional Hazards Models | Herpesvirus 6, Human - genetics | Saliva - virology | Immunoglobulin M - blood | Fever - etiology | Sex Factors | Survival Analysis | Roseolovirus Infections - complications | Exanthema Subitum - diagnosis | Care and treatment | Diagnosis | Research | Human herpesvirus 6 | Polymerase chain reaction | Infections | Deoxyribonucleic acid--DNA | Children & youth
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7. Full Text HHV-6 reactivation and its effect on delirium and cognitive functioning in hematopoietic cell transplantation recipients
by Zerr, Danielle M and Fann, Jesse R and Breiger, David and Boeckh, Michael and Adler, Amanda L and Xie, Hu and Delaney, Colleen and Huang, Meei-Li and Corey, Lawrence and Leisenring, Wendy M
Blood, ISSN 0006-4971, 05/2011, Volume 117, Issue 19, pp. 5243 - 5249
Human herpesvirus 6 (HHV-6) is detected in the plasma of approximately 40% of patients undergoing hematopoietic cell transplantation (HCT) and sporadically... 
HUMAN-HERPESVIRUS-6 DNA | LIMBIC ENCEPHALITIS | HUMAN HERPESVIRUS-6 | IMPACT | RISK-FACTORS | DISTRESS | DISEASE | INFECTION | QUALITY-OF-LIFE | RATING-SCALE | HEMATOLOGY | Delirium - epidemiology | Virus Activation - physiology | Humans | Middle Aged | Male | Herpesvirus 6, Human - physiology | Transplantation | Neuropsychological Tests | Young Adult | Roseolovirus Infections - epidemiology | Delirium - virology | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Roseolovirus Infections - virology | Cognition Disorders - virology | Roseolovirus Infections - complications | Cognition Disorders - epidemiology | Clinical Trials and Observations
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8. Full Text Chromosomally integrated human herpesvirus 6 in heart failure: prevalence and treatment
by Kühl, Uwe and Lassner, Dirk and Wallaschek, Nina and Gross, Ulrich M and Krueger, Gerhard R.F and Seeberg, Bettina and Kaufer, Benedikt B and Escher, Felicitas and Poller, Wolfgang and Schultheiss, Heinz‐Peter
European Journal of Heart Failure, ISSN 1388-9842, 01/2015, Volume 17, Issue 1, pp. 9 - 19
Aims Human herpesvirus 6 (HHV‐6) A and B are two betaherpesviruses that are associated with many conditions including roseola, drug‐induced hypersensitivity... 
Myocarditis | Treatment | Cardiomyopathy | Chromosomally integrated human herpesvirus 6 | ERYTHROVIRUS | MYOCARDIUM | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PERSISTENCE | IDENTIFICATION | VARIANT | HUMAN-HERPESVIRUS-6 | GENOMES | INFECTION | Prevalence | Prospective Studies | Humans | Middle Aged | Male | Viral Load | Roseolovirus Infections - drug therapy | Roseolovirus Infections - epidemiology | Heart Failure - virology | Myocarditis - epidemiology | Myocardium - metabolism | Ganciclovir - therapeutic use | Adult | Female | Heart Failure - epidemiology | Myocardium - ultrastructure | Heart - virology | Antiviral Agents - therapeutic use | Cardiomyopathy, Dilated - epidemiology | Treatment Outcome | Herpesvirus 6, Human - genetics | Microscopy, Electron | Reverse Transcriptase Polymerase Chain Reaction | Virus Integration | Cardiomyopathy, Dilated - virology | Germany - epidemiology | Myocarditis - virology | DNA, Viral - genetics | Cohort Studies
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9. Full Text Human Herpesvirus 6 (HHV-6) Reactivation and HHV-6 Encephalitis After Allogeneic Hematopoietic Cell Transplantation: A Multicenter, Prospective Study
by Masao Ogata and Takako Satou and Jun-ichi Kadota and Noriyuki Saito and Takashi Yoshida and Hirokazu Okumura and Toshimitsu Ueki and Koji Nagafuji and Shinichi Kako and Nobuhiko Uoshima and Mitsuru Tsudo and Hidekazu Itamura and Takahiro Fukuda
Clinical Infectious Diseases, ISSN 1058-4838, 9/2013, Volume 57, Issue 5, pp. 671 - 681
Background. The epidemiology of human herpesvirus 6 (HHV-6) encephalitis after allogeneic hematopoietic cell transplantation (HCT) and its relationship with... 
Polymerase chain reaction | Encephalitis | Hematocrit | Predisposing factors | Bone marrow | Transplantation | ARTICLES AND COMMENTARIES | Human herpesvirus 6 | Blood | Cell transplantation | Blood plasma | HHV-6 reactivation | human herpesvirus 6 | viral load | HHV-6 encephalitis | allogeneic hematopoietic cell transplantation | INFECTIOUS DISEASES | RISK-FACTORS | SCT | MICROBIOLOGY | CLINICAL-FEATURES | IMMUNOLOGY | RECIPIENTS | CORD BLOOD TRANSPLANTATION | HUMAN-HERPESVIRUS-6 DNA | IMPACT | PLASMA | ACUTE LIMBIC ENCEPHALITIS | DISEASE | Prospective Studies | Encephalitis, Viral - virology | Humans | Middle Aged | Male | Viral Load | Incidence | DNA, Viral - blood | Young Adult | Roseolovirus Infections - epidemiology | Cord Blood Stem Cell Transplantation - adverse effects | Adolescent | Adult | Female | Roseolovirus Infections - virology | Aged | Virus Activation | Herpesvirus 6, Human - isolation & purification | Encephalitis, Viral - epidemiology | Usage | Patient outcomes | Risk factors | Hematopoietic stem cells
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10. Full Text Acute liver dysfunction not resulting from hepatitis virus in immunocompetent children
by Tsunoda, Tomoyuki and Inui, Ayano and Iwasawa, Kentaro and Oikawa, Manari and Sogo, Tsuyoshi and Komatsu, Haruki and Ito, Yoshinori and Fujisawa, Tomoo
Pediatrics International, ISSN 1328-8067, 05/2017, Volume 59, Issue 5, pp. 551 - 556
Background The aim of the present study was to clarify the roles of cytomegalovirus (CMV), Epstein–Barr virus (EBV), and human herpesvirus 6 (HHV‐6) in... 
immunocompetent | liver failure | real‐time polymerase chain reaction | multiplex | herpesvirus | real-time polymerase chain reaction | VIRAL LOAD | DNA LOAD | CYTOMEGALOVIRUS-INFECTION | TRANSPLANT RECIPIENTS | FAILURE | REAL-TIME PCR | WHOLE-BLOOD | POLYMERASE-CHAIN-REACTION | INFANTILE HEPATITIS | PEDIATRICS | EPSTEIN-BARR-VIRUS | Prevalence | Prospective Studies | Cytomegalovirus Infections - epidemiology | Humans | Child, Preschool | Roseolovirus Infections - diagnosis | Infant | Male | Cytomegalovirus Infections - complications | Cytomegalovirus Infections - immunology | Viral Load | Roseolovirus Infections - epidemiology | Female | Immunocompetence | Child | Real-Time Polymerase Chain Reaction | Herpesvirus 6, Human - isolation & purification | Infant, Newborn | Epstein-Barr Virus Infections - epidemiology | Acute Disease | Epstein-Barr Virus Infections - immunology | Hepatic Insufficiency - virology | Roseolovirus Infections - immunology | Cytomegalovirus Infections - diagnosis | Multiplex Polymerase Chain Reaction | Adolescent | Epstein-Barr Virus Infections - complications | Epstein-Barr Virus Infections - diagnosis | Hepatic Insufficiency - immunology | Roseolovirus Infections - complications | Liver | Epstein-Barr virus | Hepatitis A | Immunoglobulin M | Multiplexing | Cytomegalovirus | Liver diseases | Hepatitis A virus | Viremia | Immunoglobulin G | Viruses | Serology | Infections | Real time | Polymerase chain reaction | Hepatitis | Poisoning | Children | Deoxyribonucleic acid--DNA
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11. Full Text Human Herpesvirus 6 Latent Infection in Patients With Glioma
by Jing Chi and Bin Gu and Chun Zhang and Guangyong Peng and Feng Zhou and Yun Chen and Guofeng Zhang and Yidi Guo and Dandan Guo and Jian Qin and Jinfeng Wang and Lingyun Li and Fang Wang and Genyan Liu and Fangyi Xie and Dongju Feng and Hong Zhou and Xingxu Huang and Shiqiang Lu and Yingxia Liu and Weixing Hu and Kun Yao
The Journal of Infectious Diseases, ISSN 0022-1899, 11/2012, Volume 206, Issue 9, pp. 1394 - 1398
The etiology of glioma remains unclear so far. Human herpesvirus 6 (HHV-6) might be associated with glioma, but there is no direct evidence to support this.... 
Polymerase chain reaction | Cytomegalovirus | Cyst Fluid | Glioma | Cytokines | Astrocytes | Specimens | Viruses | Infections | Human herpesvirus 6 | ASTROCYTOMA | CELLS | HUMAN-HERPESVIRUS-6 | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY | BRAIN-TUMORS | Carrier State - epidemiology | Glioma - etiology | Humans | Middle Aged | Cytokines - secretion | Male | Asymptomatic Diseases | Young Adult | Roseolovirus Infections - epidemiology | Carrier State - virology | Adult | Female | Roseolovirus Infections - virology | Aged | Roseolovirus Infections - complications | Herpesvirus 6, Human - isolation & purification | Glioma - virology | Herpes | Development and progression | Research | Gliomas | Analysis | Herpesvirus diseases
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12. Full Text Review part 2: Human herpesvirus‐6 in central nervous system diseases
by Yao, Karen and Crawford, John R and Komaroff, Anthony L and Ablashi, Dharam V and Jacobson, Steven
Journal of Medical Virology, ISSN 0146-6615, 10/2010, Volume 82, Issue 10, pp. 1669 - 1678
J. Med. Virol. 82:1669–1678, 2010. © 2010 Wiley‐Liss, Inc. 
HHV‐6 | central nervous system | Central nervous system | HHV-6 | LIMBIC ENCEPHALITIS | MULTIPLE-SCLEROSIS PATIENTS | HUMAN-HERPESVIRUS-6 INFECTION | CONTROL BRAIN-TISSUE | CEREBROSPINAL-FLUID | POLYMERASE-CHAIN-REACTION | VIROLOGY | FATAL ENCEPHALITIS | SERUM HHV-6 DNA | CHRONIC-FATIGUE-SYNDROME | STEM-CELL TRANSPLANTATION | Encephalitis, Viral - virology | Central Nervous System Diseases - epidemiology | Humans | Multiple Sclerosis - virology | Multiple Sclerosis - epidemiology | Central Nervous System Diseases - virology | Roseolovirus Infections - epidemiology | Epilepsy, Temporal Lobe - virology | Fatigue Syndrome, Chronic - virology | Epilepsy, Temporal Lobe - epidemiology | Roseolovirus Infections - virology | Fatigue Syndrome, Chronic - epidemiology | Herpesvirus 6, Human - isolation & purification | Encephalitis, Viral - epidemiology
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