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1. Full Text Cholesterol-independent neuroprotective and neurotoxic activities of statins: Perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders
by Butterfield, D. Allan and Barone, Eugenio and Mancuso, Cesare
Pharmacological research, ISSN 1043-6618, 09/2011, Volume 64, Issue 3, pp. 180 - 186
.... However, it is not clear that the purported effectiveness of statins in neurodegenerative disorders is directly related to cholesterol-lowering effects of these agents... 
Alzheimer disease | Pleiotropic functions | Statins | Statins as Janus molecules | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Fatty Acids, Monounsaturated - pharmacology | Lovastatin - pharmacology | Heptanoic Acids - therapeutic use | Humans | Heptanoic Acids - adverse effects | Neurodegenerative Diseases - drug therapy | Quinolines - pharmacology | Fluorobenzenes - pharmacology | Fatty Acids, Monounsaturated - therapeutic use | Fatty Acids, Monounsaturated - adverse effects | Pyrroles - adverse effects | Indoles - pharmacology | Pyrroles - therapeutic use | Heptanoic Acids - pharmacology | Lovastatin - therapeutic use | Lovastatin - adverse effects | Alzheimer Disease - drug therapy | Rosuvastatin Calcium | Pyrimidines - pharmacology | Cholesterol - metabolism | Sulfonamides - pharmacology | Atorvastatin Calcium | Pyrroles - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Indoles - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Sulfonamides - adverse effects | Indoles - therapeutic use | Fluorobenzenes - adverse effects | Quinolines - therapeutic use | Fluorobenzenes - therapeutic use | Quinolines - adverse effects | Alzheimer's disease | Neuroprotection | Neurotoxicity | Neurodegenerative diseases | statins | Dyslipidemia | Clinical trials | Age | Cholesterol | Index Medicus
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2. Full Text Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease
by Yusuf, Salim and Lonn, Eva and Pais, Prem and Bosch, Jackie and López-Jaramillo, Patricio and Zhu, Jun and Xavier, Denis and Avezum, Alvaro and Leiter, Lawrence A and Piegas, Leopoldo S and Parkhomenko, Alexander and Keltai, Matyas and Keltai, Katalin and Sliwa, Karen and Chazova, Irina and Peters, Ron J.G and Held, Claes and Yusoff, Khalid and Lewis, Basil S and Jansky, Petr and Khunti, Kamlesh and Toff, William D and Reid, Christopher M and Varigos, John and Accini, Jose L and McKelvie, Robert and Pogue, Janice and Jung, Hyejung and Liu, Lisheng and Diaz, Rafael and Dans, Antonio and Dagenais, Gilles and HOPE-3 Investigators
The New England journal of medicine, ISSN 1533-4406, 05/2016, Volume 374, Issue 21, pp. 2032 - 2043
... – 4 Therefore, combined lowering of LDL cholesterol and blood pressure can potentially have a bigger effect in reducing cardiovascular events than either intervention alone... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Risk Factors | Rosuvastatin Calcium - adverse effects | Antihypertensive Agents - administration & dosage | Hypertension - drug therapy | Male | Hydrochlorothiazide - administration & dosage | Rosuvastatin Calcium - administration & dosage | Antihypertensive Agents - adverse effects | Medication Adherence | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Benzimidazoles - administration & dosage | Tetrazoles - administration & dosage | Cardiovascular Diseases - epidemiology | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Care and treatment | Usage | Clinical trials | Rosuvastatin | Dosage and administration | Cardiovascular diseases | Risk factors | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Antihypertensives | Cardiovascular disease | Lipids | Hydrochlorothiazide | Low density lipoprotein | Cholesterol | Disease prevention | Blood pressure | Health risk assessment | Drug therapy | Heart diseases | Index Medicus | Abridged Index Medicus
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3. Full Text Rosuvastatin in Older Patients with Systolic Heart Failure
by Kjekshus, John and Apetrei, Eduard and Barrios, Vivencio and Böhm, Michael and Cleland, John G.F and Cornel, Jan H and Dunselman, Peter and Fonseca, Cândida and Goudev, Assen and Grande, Peer and Gullestad, Lars and Hjalmarson, Åke and Hradec, Jaromir and Jánosi, András and Kamenský, Gabriel and Komajda, Michel and Korewicki, Jerzy and Kuusi, Timo and Mach, François and Mareev, Vyacheslav and McMurray, John J.V and Ranjith, Naresh and Schaufelberger, Maria and Vanhaecke, Johan and van Veldhuisen, Dirk J and Waagstein, Finn and Wedel, Hans and Wikstrand, John and CORONA Grp and CORONA Group and Wallenberg Laboratory and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Wallenberglaboratoriet
The New England journal of medicine, ISSN 1533-4406, 11/2007, Volume 357, Issue 22, pp. 2248 - 2261
In this clinical trial, rosuvastatin was compared with placebo in elderly patients with systolic, ischemic heart failure. Although rosuvastatin significantly... 
TRIAL | SURVIVAL | EVENTS | MYOCARDIAL-INFARCTION | CHOLESTEROL LEVELS | MERIT-HF | DISEASE | PRAVASTATIN | DEATH | STATINS | UMCG Approved | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Single-Blind Method | Follow-Up Studies | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Systole | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Heart Failure - etiology | Proportional Hazards Models | Rosuvastatin Calcium | Treatment Outcome | Heart Failure - drug therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Myocardial Ischemia - complications | Pyrimidines - adverse effects | Sulfonamides - adverse effects | Aged | Fluorobenzenes - adverse effects | Fluorobenzenes - therapeutic use | Heart failure | Placebos | Rosuvastatin | Dosage and administration | Drug therapy | Comparative analysis | Cardiovascular disease | Heart attacks | Index Medicus | Abridged Index Medicus | Cardiovascular Diseases | MEDICIN OCH HÄLSOVETENSKAP | Myocardial Ischemia | epidemiology | Pyrimidines | Heart Failure | Hydroxymethylglutaryl-CoA Reductase Inhibitors | MEDICAL AND HEALTH SCIENCES | drug therapy | complications | Fluorobenzenes | Hospitalization | etiology | statistics & numerical data | Sulfonamides | mortality | adverse effects | therapeutic use
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4. Full Text Effect of Two Intensive Statin Regimens on Progression of Coronary Disease
by Nicholls, Stephen J and Ballantyne, Christie M and Barter, Philip J and Chapman, M. John and Erbel, Raimund M and Libby, Peter and Raichlen, Joel S and Uno, Kiyoko and Borgman, Marilyn and Wolski, Kathy and Nissen, Steven E
The New England journal of medicine, ISSN 1533-4406, 12/2011, Volume 365, Issue 22, pp. 2078 - 2087
In this trial, intravascular ultrasonography was used to compare the effects of atorvastatin versus rosuvastatin on regression of coronary atherosclerosis... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Coronary Vessels - diagnostic imaging | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Ultrasonography, Interventional | Male | Heptanoic Acids - adverse effects | Coronary Artery Disease - pathology | Pyrroles - adverse effects | Cholesterol, LDL - blood | Female | Pyrroles - therapeutic use | Coronary Vessels - pathology | Double-Blind Method | Rosuvastatin Calcium | Coronary Artery Disease - drug therapy | Anticholesteremic Agents - adverse effects | Disease Progression | Atorvastatin Calcium | Coronary Artery Disease - diagnostic imaging | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Cholesterol, HDL - blood | Sulfonamides - adverse effects | Aged | Fluorobenzenes - adverse effects | Fluorobenzenes - therapeutic use | Drugs | Rosuvastatin | Dosage and administration | Product/Service Evaluations | Drug therapy | Atherosclerosis | Lipoproteins (low density) | Clinical trials | Cardiovascular disease | Patients | Cholesterol | Studies | Side effects | Ultrasonic imaging | Arteriosclerosis | Atorvastatin | Heart diseases | Lipoproteins (high density) | Ultrasound | Statins | Index Medicus | Abridged Index Medicus
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5. Full Text Differential Effects of Tipranavir plus Ritonavir on Atorvastatin or Rosuvastatin Pharmacokinetics in Healthy Volunteers
by Pham, P. A and la Porte, C. J. L and Lee, L. S and van Heeswijk, R and Sabo, J. P and Elgadi, M. M and Piliero, P. J and Barditch-Crovo, P and Fuchs, E and Flexner, C and Cameron, D. W
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 08/2009, Volume 53, Issue 10, pp. 4385 - 4392
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fluorobenzenes - pharmacokinetics | Pyrroles - pharmacokinetics | Heptanoic Acids - pharmacokinetics | Humans | Middle Aged | Pyridines - pharmacokinetics | Male | Heptanoic Acids - adverse effects | Young Adult | Pyridines - adverse effects | Drug Interactions | Ritonavir - adverse effects | Pyrroles - adverse effects | Adult | Female | Anti-HIV Agents - adverse effects | Rosuvastatin Calcium | Sulfonamides - pharmacokinetics | Atorvastatin Calcium | Pyrones - adverse effects | Ritonavir - pharmacokinetics | Anti-HIV Agents - pharmacokinetics | Adolescent | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Sulfonamides - adverse effects | Aged | Fluorobenzenes - adverse effects | Pyrones - pharmacokinetics | Index Medicus | Pharmacology
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6. Full Text Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLARSTELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)
by Jones, Peter H and Davidson, Michael H and Stein, Evan A and Bays, Harold E and McKenney, James M and Miller, Elinor and Cain, Valerie A and Blasetto, James W and STELLAR Study Group
The American journal of cardiology, ISSN 0002-9149, 07/2003, Volume 92, Issue 2, pp. 152 - 160
The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with atorvastatin, pravastatin, and... 
Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Simvastatin - therapeutic use | Simvastatin - adverse effects | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Male | Fluorobenzenes - administration & dosage | Heptanoic Acids - adverse effects | Hypercholesterolemia - drug therapy | Dose-Response Relationship, Drug | Pyrimidines | Time Factors | Pyrroles - administration & dosage | Aged, 80 and over | Heptanoic Acids - administration & dosage | Pravastatin - adverse effects | Pyrroles - adverse effects | Adult | Cholesterol, LDL - blood | Female | Pyrroles - therapeutic use | Pravastatin - therapeutic use | Hypercholesterolemia - blood | Simvastatin - administration & dosage | Rosuvastatin Calcium | Cholesterol, LDL - drug effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Pravastatin - administration & dosage | Sulfonamides | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Atorvastatin | Aged | Fluorobenzenes - adverse effects | Fluorobenzenes - therapeutic use | Comparative analysis | Drug therapy | Safety | Index Medicus | Abridged Index Medicus
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7. Full Text Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein
by Ridker, Paul M and Danielson, Eleanor and Fonseca, Francisco A.H and Genest, Jacques and Gotto, Antonio M and Kastelein, John J.P and Koenig, Wolfgang and Libby, Peter and Lorenzatti, Alberto J and MacFadyen, Jean G and Nordestgaard, Børge G and Shepherd, James and Willerson, James T and Glynn, Robert J and JUPITER Study Grp and JUPITER Study Group
The New England journal of medicine, ISSN 1533-4406, 11/2008, Volume 359, Issue 21, pp. 2195 - 2207
In this trial, 17,802 healthy men and women with low-density lipoprotein cholesterol levels of less than 130 mg per deciliter and high-sensitivity C-reactive... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Myocardial Infarction - epidemiology | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Male | C-Reactive Protein - metabolism | Cardiovascular Diseases - blood | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Stroke - epidemiology | Muscular Diseases - chemically induced | Stroke - prevention & control | Double-Blind Method | Kaplan-Meier Estimate | Proportional Hazards Models | Rosuvastatin Calcium | Biomarkers - blood | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Sulfonamides - adverse effects | Diabetes Mellitus - chemically induced | Aged | Fluorobenzenes - adverse effects | Myocardial Infarction - prevention & control | Fluorobenzenes - therapeutic use | Prevention | Usage | C-reactive protein | Rosuvastatin | Cardiovascular diseases | Drug therapy | Health aspects | Proteins | Cardiovascular disease | Heart attacks | Cholesterol | Statins | Index Medicus | Abridged Index Medicus
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8. Full Text Risk of incident diabetes among patients treated with statins: population based study
by Carter, Aleesa A and Gomes, Ta