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Neurotoxicology, ISSN 0161-813X, 06/2012, Volume 33, Issue 3, pp. 482 - 490
► Rutin inhibits Aβ42 fibrillization and attenuates Aβ42-induced cytotoxicity. ► Rutin decreases the formation of active oxygen species (ROS). ► Rutin... 
Aggregation | Reactive oxygen species | Nitric oxide | β-Amyloid | Proinflammatory cytokines | Rutin | Alzheimer's disease | TEA EPIGALLOCATECHIN-3-GALLATE EGCG | INDUCED MITOCHONDRIAL DYSFUNCTION | CELLS | PROTEIN | ALZHEIMERS-DISEASE | NEUROSCIENCES | PEPTIDE | OLIGOMERS | QUERCETIN | MOUSE MODEL | beta-Amyloid | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TRANSGENIC MICE | Tumor Necrosis Factor-alpha - metabolism | Neurons - pathology | Reactive Oxygen Species - metabolism | Glutathione - metabolism | Humans | Rutin - pharmacology | Dose-Response Relationship, Drug | Neuroprotective Agents - pharmacology | Time Factors | Interleukin-1beta - metabolism | Amyloid beta-Peptides - metabolism | Inflammation Mediators - metabolism | Neurons - metabolism | Neurons - drug effects | Superoxide Dismutase - metabolism | Cytoprotection | Malondialdehyde - metabolism | Glutathione Peroxidase - metabolism | Peptide Fragments - metabolism | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Down-Regulation | Neurons - immunology | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Mitochondria - pathology | Catalase - metabolism | Cell Line, Tumor | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Nitric Oxide Synthase Type II - metabolism | Index Medicus | Oxidative stress | oxides | Cytotoxicity | Superoxide dismutase | beta -Amyloid | rutin | Neuroblastoma cells | Prevention | Fibrillogenesis | Mitochondria | Neurotoxicity | Catalase | Etiology | Interleukin 1 | Glutathione peroxidase | Oxygen | Deposits | Cytokines | Neurodegenerative diseases | Inflammation | Malondialdehyde | Nitric-oxide synthase | Microglia | Diets | Flavonoids | Tumor necrosis factor- alpha
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0168525 - e0168525
Development of an effective radio protector to minimise radiation-inflicted damages have largely failed owing to inherent toxicity of most of the agents... 
ACTIVE PRINCIPLES | IN-VITRO | ACTIVATION | PROTECTION | HEXANDRUM | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | MOUSE | KAPPA-B | IONIZING-RADIATION | DAMAGE | Radiation-Protective Agents | Tumor Necrosis Factor-alpha - metabolism | Heme Oxygenase-1 - metabolism | Podophyllotoxin - pharmacology | Radiation Injuries - drug therapy | Reactive Oxygen Species - metabolism | Rutin - pharmacology | Lipopolysaccharides - metabolism | Gastrointestinal Tract - radiation effects | Male | NF-kappa B - metabolism | Interleukin-6 - metabolism | Mice, Inbred C57BL | Tumor Suppressor Protein p53 - metabolism | Gastrointestinal Tract - drug effects | Dinoprostone - metabolism | Drug Therapy, Combination - methods | Animals | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Cyclooxygenase 2 - metabolism | Mice | Nitric Oxide - metabolism | Radiation Injuries - metabolism | Nitric Oxide Synthase Type II - metabolism | Mucosa | p53 Protein | Radiation | Cancer therapies | Prostaglandin endoperoxide synthase | Bone marrow | Growth factors | Medical research | NF-κB protein | Radiation effects | Cytokines | Cell division | Exposure | Nitric-oxide synthase | Inflammatory bowel disease | Disease prevention | Oxygenase | Tumor necrosis factor | Nitric oxide | Crypts | Stem cells | Leukocytes (granulocytic) | Radiation damage | Nuclear medicine | Podophyllotoxin | Toxicity | Interleukin | Irradiated | Prostaglandin E2 | Interleukin 6 | Pathways | Granulocyte colony-stimulating factor | Intestine | Rodents | Radiation injuries | Colony-stimulating factor | Injuries | Translocation | Inflammation | Radiation therapy | Rutin | Nuclear transport | Hemopoiesis | Signaling | Cell death | Fatalities | Cyclooxygenase-2 | Apoptosis | Index Medicus
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 07/2017, Volume 22, Issue 7, p. 1160
Tartary buckwheat (Fagopyrum tataricum) has been established globally as a nutritionally important food item, particularly owing to high levels of bioactive... 
inflammatory response | 3T3-L1 adipocytes | adipogenesis | tartary buckwheat | HIGH-FAT DIET | CHEMISTRY, ORGANIC | KAPPA-B | ANTIOXIDANT PROPERTIES | FAGOPYRUM-TATARICUM-GAERTN | INDUCED OXIDATIVE STRESS | INSULIN-RESISTANCE | GENE-EXPRESSION | PPAR-GAMMA | ADIPOSE-TISSUE | Tumor Necrosis Factor-alpha - metabolism | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Fatty Acid Synthases - metabolism | Obesity - drug therapy | Plant Extracts - pharmacology | Adipogenesis - drug effects | Rutin - pharmacology | Adipocytes - cytology | Adipocytes - drug effects | PPAR gamma - metabolism | Inflammation - metabolism | Cell Differentiation | Interleukin-6 - metabolism | Nitric Oxide - biosynthesis | Fagopyrum - chemistry | Obesity - complications | 3T3-L1 Cells | Obesity - metabolism | Triglycerides - metabolism | Glycerolphosphate Dehydrogenase - metabolism | Animals | Adipocytes - metabolism | Rutin - administration & dosage | Lipid Metabolism - drug effects | Rutin - chemistry | Mice | Rutin - therapeutic use | Acetyl-CoA Carboxylase - metabolism | Interleukin | Buckwheat | Inflammatory response | mRNA | CCAAT/enhancer-binding protein | Adipocytes | Desaturase | Interleukin 6 | Proteins | Acetyl-CoA carboxylase | Glycerol-3-phosphate | Bioactive compounds | Tumor necrosis factor-TNF | Adipogenesis | Food | Glycerol-3-phosphate dehydrogenase | Glycerol | Stearoyl-CoA desaturase | Inflammation | Tumor necrosis factor-α | Rutin | Fatty acids | Fatty-acid synthase | Nitric-oxide synthase | Monocytes | Monocyte chemoattractant protein | Nitric oxide | Peroxisome proliferator-activated receptors | Monocyte chemoattractant protein 1
Journal Article
Journal Article
Journal Article
Food and Function, ISSN 2042-6496, 05/2018, Volume 9, Issue 5, pp. 2922 - 2930
Little is still known about brain protein synthesis. In order to increase our knowledge of it, we aimed to modulate brain protein synthesis rates through... 
INSULIN | SUPPLEMENTATION | VITAMIN-E | RISK-FACTOR | INDUCED OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | DISEASE | GENE-EXPRESSION | FAT | COGNITIVE IMPAIRMENT | SPATIAL MEMORY | Vitamin A - pharmacology | Rutin - metabolism | Rats, Wistar | Selenium - pharmacology | Zinc - metabolism | Humans | Rutin - pharmacology | Aging - drug effects | Micronutrients - metabolism | Male | Brain - growth & development | Hippocampus - drug effects | Interleukin-1beta - genetics | Dietary Supplements - analysis | Vitamin A - metabolism | Brain - metabolism | Interleukin-1beta - metabolism | NF-E2-Related Factor 2 - genetics | Nutritional Status | Dietary Sucrose - metabolism | Hippocampus - growth & development | Interleukin-6 - metabolism | Interleukin-6 - genetics | Rats | Vitamin D - pharmacology | Brain - drug effects | Hippocampus - metabolism | Animals | Selenium - metabolism | Micronutrients - pharmacology | NF-E2-Related Factor 2 - metabolism | Vitamin E - metabolism | Dietary Sucrose - adverse effects | Protein Biosynthesis - drug effects | Vitamin D - metabolism | Zinc - pharmacology | Aging - metabolism | Vitamin E - pharmacology | Cerebellum | Brain | Transcription factors | Sucrose | Interleukin 6 | Proteins | Antioxidants | Catalase | Vitamin E | Rodents | Heme | Aging | Peroxidase | Selenium | Supplementation | Sugars | Glutathione | Glutathione peroxidase | Cytokines | Starch | Dietary supplements | Protein biosynthesis | Inflammation | Tumor necrosis factor-α | Rutin | Gene expression | Zinc | Oxygenase | Micronutrients | Diet | Protein synthesis | High protein diet | Tocopherol | Wheat | Hippocampus | Life Sciences | Food and Nutrition
Journal Article
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 01/2014, Volume 14, Issue 1, pp. 21 - 21
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 08/2017, Volume 274, pp. 89 - 99
Rutin is a glycosylated flavonoid present in many fruits and plants that has been demonstrated to have anti-inflammatory and antioxidant properties. However,... 
LPS arginase | M2 (CD150/CD206) phenotype | Rutin | Flavonoid | Microglia | OXIDATIVE STRESS | MICROGLIAL ACTIVATION | ALZHEIMERS-DISEASE | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITION | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | TOXICOLOGY | CHEMOKINE RECEPTORS | EXPRESSION | BRAIN | Mannose-Binding Lectins - metabolism | Microglia - metabolism | Rats, Wistar | Cytokines - analysis | Rutin - pharmacology | Lectins, C-Type - metabolism | Signaling Lymphocytic Activation Molecule Family Member 1 - metabolism | Flavonoids - pharmacology | Microglia - cytology | Lipopolysaccharides - toxicity | Microglia - drug effects | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Rats | Receptors, Cell Surface - metabolism | Macrophages - cytology | Macrophages - metabolism | Phenotype | Animals | Anti-Inflammatory Agents - chemistry | Transforming Growth Factor beta - genetics | Cyclooxygenase 2 - metabolism | Macrophages - drug effects | Rutin - chemistry | Cell Proliferation - drug effects | Macrophage Activation - drug effects | Nitric Oxide - metabolism | Flavonoids - chemistry | Interleukin-18 - genetics | Transforming Growth Factor beta - metabolism | Interleukin-18 - metabolism | Genetic aspects | RNA | Transforming growth factors | Mitogens | Nitric oxide | Cells | Index Medicus
Journal Article