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Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15148 - 15157
Several behavioral effects of nicotine are mediated by changes in serotonin (5-HT) release in brain areas that receive serotonergic afferents from the dorsal... 
Electric Stimulation | Rats, Wistar | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotinic Antagonists - pharmacology | Raphe Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Nicotine - pharmacology | Excitatory Postsynaptic Potentials - physiology | Muscarinic Antagonists - pharmacology | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Cadmium Chloride - pharmacology | Cholinergic Agonists - pharmacology | Ryanodine - pharmacology | Animals, Newborn | Serotonergic Neurons - physiology | Presynaptic Terminals - drug effects | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Glutamic Acid - physiology | Rats | Atropine - pharmacology | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Chelating Agents - pharmacology | Aconitine - pharmacology | GABA Antagonists - pharmacology | Physostigmine - pharmacology | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Receptors, Nicotinic - physiology | Nicotine - analogs & derivatives | Serotonin - metabolism | In Vitro Techniques | Serotonergic Neurons - cytology | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2011, Volume 301, Issue 3, pp. C559 - C565
Deliu E, Tica AA, Motoc D, Brailoiu GC, Brailoiu E. Intracellular angiotensin II activates rat myometrium. Am J Physiol Cell Physiol 301: C559-C565, 2011.... 
Calcium imaging | Microinjection | Cytosolic calcium concentration | Endoplasmic reticulum | CYCLIC ADP-RIBOSE | PHYSIOLOGY | ANG-II | LIVER LYSOSOMES | RECEPTOR | microinjection | METABOLIC-CLEARANCE | BLOOD-PRESSURE | UTERINE | CELL BIOLOGY | SIGNAL-TRANSDUCTION | RENAL ENDOSOMES | SMOOTH-MUSCLE-CELLS | calcium imaging | cytosolic calcium concentration | endoplasmic reticulum | Myometrium - drug effects | Type C Phospholipases - metabolism | Brefeldin A - pharmacology | Angiotensin II Type 1 Receptor Blockers - pharmacology | Autophagy - drug effects | Endosomes - metabolism | Angiotensin II Type 2 Receptor Blockers - pharmacology | Macrocyclic Compounds - pharmacology | Saralasin - pharmacology | Endoplasmic Reticulum - drug effects | Estrenes - pharmacology | Myometrium - metabolism | Inositol 1,4,5-Trisphosphate Receptors - antagonists & inhibitors | Ryanodine - pharmacology | Angiotensin II - pharmacology | Pyridines - administration & dosage | Endocytosis - drug effects | Enzyme Inhibitors - pharmacology | Losartan - pharmacology | Saralasin - administration & dosage | Rats | Imidazoles - pharmacology | Piperazines - pharmacology | Rats, Sprague-Dawley | Receptor, Angiotensin, Type 2 - metabolism | Signal Transduction - drug effects | Calcium Signaling - drug effects | Models, Biological | Receptor, Angiotensin, Type 1 - metabolism | Oxazoles - pharmacology | Losartan - administration & dosage | Angiotensin II - administration & dosage | Calcium Signaling - physiology | Endoplasmic Reticulum - metabolism | Imidazoles - administration & dosage | Type C Phospholipases - antagonists & inhibitors | Lysosomes - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Pyrrolidinones - pharmacology | Macrolides - pharmacology | NADP - analogs & derivatives | Female | NADP - metabolism | Heparin - pharmacology | Angiotensin II - metabolism | Arsenicals - pharmacology | Cells, Cultured | Sirolimus - pharmacology | Myometrium - cytology | Animals | Egtazic Acid - pharmacology | Uterus - cytology | Signal Transduction - physiology | Pyridines - pharmacology | Carbolines - pharmacology | Myometrium | Cell receptors | Calcium channels | Genetic aspects | Properties | Angiotensin | T cell receptors | Calcium | ACE inhibitors | Autophagy | Rodents | Index Medicus | Receptors and Signal Transduction
Journal Article
Neuropharmacology, ISSN 0028-3908, 2005, Volume 48, Issue 8, pp. 1086 - 1096
Exogenously administered cannabinoids are neuroprotective in several different cellular and animal models. In the current study, two cannabinoid CB1 receptor... 
Protein kinase A | Neuroprotection | Cannabinoids | Phosphorylation | FURA-2 | Intracellular calcium | NMDA-excitotoxicity | Ryanodine receptor | Calcium imaging | DEPENDENT PHOSPHORYLATION | calcium imaging FURA-2 | ENDOCANNABINOID SYSTEM | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | POTASSIUM A-CURRENT | RAT HIPPOCAMPAL-NEURONS | CYCLIC-AMP ACCUMULATION | RECEPTOR MODULATION | SKELETAL-MUSCLE | CA2+-INDUCED CA2+ RELEASE | neuroprotection | cannabinoids | PHARMACOLOGY & PHARMACY | intracellular calcium | ENDOPLASMIC-RETICULUM | ryanodine receptor | protein kinase A | phosphorylation | Okadaic Acid - pharmacology | Calcium - metabolism | Hippocampus - drug effects | Rats, Inbred Strains | Macrocyclic Compounds - pharmacology | N-Methylaspartate - pharmacology | Drug Interactions | Neuroprotective Agents - pharmacology | Receptor, Cannabinoid, CB1 - agonists | Cyclic AMP - analogs & derivatives | Piperidines - pharmacology | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Fetus | Neurons - metabolism | Cell Culture Techniques | Cell Death - drug effects | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclohexanols - pharmacology | Neurons - drug effects | Ryanodine - pharmacology | Pyrazoles - pharmacology | Morpholines - pharmacology | Rats | Dantrolene - pharmacology | Thionucleotides - pharmacology | Naphthalenes - pharmacology | Cyclic AMP - pharmacology | Hippocampus - metabolism | Animals | Benzoxazines - pharmacology | Oxazoles - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Phenols | Adenylate cyclase | Methyl aspartate | Cell research | Calcium channels | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2005, Volume 102, Issue 52, pp. 19144 - 19149
Central nervous system responses to cannabis are primarily mediated by CB 1 receptors, which couple preferentially to G i/o G proteins. Here, we used calcium... 
Aminoalkylindole | Inositol phosphate | Neurons | Phospholipase C | Analgesics - pharmacology | Calcium - metabolism | Humans | Endoplasmic Reticulum - metabolism | Type C Phospholipases - metabolism | Cytoplasm - metabolism | Benzoxazines | Arachidonic Acids - chemistry | Calcium - chemistry | GTP-Binding Protein alpha Subunits, Gq-G11 - chemistry | Piperidines - pharmacology | Time Factors | Dronabinol - analogs & derivatives | Fluorescent Dyes - pharmacology | Receptor, Cannabinoid, CB1 - chemistry | Neurons - metabolism | Cyclohexanols - pharmacology | Dronabinol - pharmacology | Immunosuppressive Agents - pharmacology | Endocannabinoids | Ryanodine - pharmacology | Pertussis Toxin - pharmacology | Pyrazoles - pharmacology | Cell Line | Glycerides - chemistry | Cannabinoids - chemistry | Morpholines - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | GTP-Binding Protein alpha Subunits, Gq-G11 - physiology | Fura-2 - analogs & derivatives | Naphthalenes - pharmacology | Hippocampus - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Animals | Fura-2 - pharmacology | Protein Binding | Protein Conformation | DNA, Complementary - metabolism | Proteins | Neurology | Marijuana | Inhibitor drugs | Calcium | Index Medicus | phospholipase C | Biological Sciences | aminoalkylindole | neurons | inositol phosphate
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2008, Volume 294, Issue 5, pp. 2031 - 2039
This study determined the role of a slowly inactivating component of sodium current (INa), late INa, to induce delayed afterdepolarizations (DADs) and... 
Calcium overload | Action potential | Transient inward current | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | PIG VENTRICULAR MYOCYTES | HEART-FAILURE | NA+ CHANNELS | transient inward current | ANTIANGINAL AGENT | action potential | PURKINJE-FIBERS | TOXIN ATX-II | DOG HEART | RANOLAZINE | PERIPHERAL VASCULAR DISEASE | LONG QT SYNDROME | calcium overload | Up-Regulation | Calcium - metabolism | Anti-Arrhythmia Agents - pharmacology | Ryanodine Receptor Calcium Release Channel - metabolism | Sodium - metabolism | Thiourea - pharmacology | Cnidarian Venoms - pharmacology | Ranolazine | Action Potentials | Time Factors | Sodium-Calcium Exchanger - metabolism | Egtazic Acid - analogs & derivatives | Sodium Channels - metabolism | Tachycardia, Supraventricular - metabolism | Sodium-Calcium Exchanger - antagonists & inhibitors | Tetrodotoxin - pharmacology | Ryanodine - pharmacology | Acetanilides - pharmacology | Guinea Pigs | Heart Conduction System - metabolism | Heart Atria - cytology | Sodium Channel Blockers - pharmacology | Ryanodine Receptor Calcium Release Channel - drug effects | Sodium Channels - drug effects | Cardiotonic Agents - pharmacology | Chelating Agents - pharmacology | Piperazines - pharmacology | Heart Atria - metabolism | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Myocytes, Cardiac - drug effects | Heart Conduction System - physiopathology | Myocytes, Cardiac - metabolism | Tachycardia, Supraventricular - physiopathology | Thiourea - analogs & derivatives | Proteins | Cardiovascular system | Toxins | Sodium | Calcium | Cells | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2003, Volume 369, Issue 2, pp. 287 - 299
Journal Article
Neuroscience, ISSN 0306-4522, 2015, Volume 303, pp. 577 - 585
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 05/2004, Volume 19, Issue 9, pp. 2464 - 2474
A major subtype of glutamate receptors, AMPA receptors (AMPARs), are generally thought to mediate excitation at mammalian central synapses via the ionotropic... 
Cerebellum | Presynaptic inhibition | AMPA-type glutamate receptor | Rat | GABAergic inhibitory synapse | Glycine - analogs & derivatives | Rats, Wistar | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Benzoxazines | Neural Inhibition - physiology | Drug Interactions | Piperidines - pharmacology | Egtazic Acid - analogs & derivatives | Neurons - physiology | Neurons - drug effects | Action Potentials - drug effects | Ryanodine - pharmacology | Cyclopropanes - pharmacology | Pyrazoles - pharmacology | Synapses - drug effects | Triazines - pharmacology | Presynaptic Terminals - drug effects | Receptors, AMPA - physiology | Colforsin - pharmacology | Synapses - physiology | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Chelating Agents - pharmacology | Calcium Channel Blockers - pharmacology | Benzothiadiazines - pharmacology | GABA Antagonists - pharmacology | Naphthalenes - pharmacology | Triazoles - pharmacology | Animals | Egtazic Acid - pharmacology | Glycine - pharmacology | Cerebellum - cytology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | In Vitro Techniques | Neural Inhibition - drug effects | Receptors, AMPA - drug effects | Index Medicus | presynaptic inhibition | rat | cerebellum
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2006, Volume 26, Issue 2, pp. 696 - 707
Natriuretic peptides (NPs) may work as neuromodulators through their associated receptors [NP receptors (NPRs)]. By immunocytochemistry, we showed that NPR-A... 
Brain natriuretic peptide | GABA receptor | Retina | Intracellular calcium | Neuromodulation | Bipolar cells | ATRIAL MYOCYTES | CA2+ RELEASE | brain natriuretic peptide | bipolar cells | DEPENDENT PROTEIN-KINASE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | neuromodulation | CGMP-ACTIVATED CHANNELS | retina | RYANODINE RECEPTORS | GANGLION-CELLS | NITRIC-OXIDE | intracellular calcium | GUANYLYL CYCLASE RECEPTORS | Calcium-Transporting ATPases - antagonists & inhibitors | Cyclic GMP - pharmacology | Calcium - metabolism | Male | Peptide Fragments - pharmacology | Peptides, Cyclic - pharmacology | Natriuretic Peptide, Brain - pharmacology | Natriuretic Peptide, Brain - physiology | Macrocyclic Compounds | Guanylate Cyclase - drug effects | Cyclic GMP-Dependent Protein Kinases - physiology | Cyclic GMP - analogs & derivatives | Retinal Bipolar Cells - physiology | Guanylate Cyclase - physiology | Receptors, GABA-A - drug effects | Caffeine - pharmacology | Inositol 1,4,5-Trisphosphate Receptors | Indoles - pharmacology | Atrial Natriuretic Factor - pharmacology | Heparin - pharmacology | Ryanodine - pharmacology | Membrane Potentials - drug effects | Calcium Channels | GABA-A Receptor Antagonists | Rats | gamma-Aminobutyric Acid - pharmacology | Imidazoles - pharmacology | Ryanodine Receptor Calcium Release Channel - drug effects | Retinal Bipolar Cells - drug effects | Rats, Sprague-Dawley | Polysaccharides - pharmacology | Receptors, Atrial Natriuretic Factor - physiology | Calmodulin - physiology | Patch-Clamp Techniques | Animals | Ruthenium Red - pharmacology | Calcium Signaling - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Thapsigargin - pharmacology | Natriuretic Peptide, Brain - antagonists & inhibitors | Oxazoles - pharmacology | Protein Kinase Inhibitors - pharmacology | Receptors, Atrial Natriuretic Factor - drug effects | Carbazoles - pharmacology | Receptors, GABA - physiology | Calmodulin - antagonists & inhibitors | Index Medicus | Cellular | Molecular
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 11/2018, Volume 123, Issue 5, pp. 567 - 576
Interstitial cystitis is a syndrome characterized by detrusor overactivity and chronic inflammation of the bladder. The mechanisms responsible for the altered... 
HEMORRHAGIC CYSTITIS | INOSITOL 1,4,5-TRISPHOSPHATE | NONMUSCLE MYOSIN-II | ADENINE-DINUCLEOTIDE PHOSPHATE | CA2+ RELEASE | CALCIUM-RELEASE | CYCLOPHOSPHAMIDE CYSTITIS | PHARMACOLOGY & PHARMACY | INTESTINAL SMOOTH-MUSCLE | LUMINAL CA2 | TOXICOLOGY | LOWER URINARY-TRACT | Amides - pharmacology | Signal Transduction | Urinary Bladder - metabolism | Enzyme Inhibitors - pharmacology | Maleimides - pharmacology | Rats | Cystitis, Interstitial - physiopathology | Ryanodine Receptor Calcium Release Channel - metabolism | rhoA GTP-Binding Protein - metabolism | Carbachol - pharmacology | Animals | rho-Associated Kinases - metabolism | Muscle Contraction - drug effects | Protein Kinase C - metabolism | Muscle Relaxants, Central - pharmacology | Inositol 1,4,5-Trisphosphate Receptors - antagonists & inhibitors | Urinary Bladder - physiopathology | Indoles - pharmacology | Pyridines - pharmacology | Sarcoplasmic Reticulum - metabolism | Cholinergic Agonists - pharmacology | Cystitis, Interstitial - metabolism | Heparin - pharmacology | Ryanodine - pharmacology | Carbachol | Cardiotonic agents | Protein kinases | Cystitis | Cardiac glycosides | Ryanodine | Protein kinase C | Calcium | Acetylcholine receptors (muscarinic) | Bladder | Smooth muscle | Intracellular signalling | Kinases | Contraction | Proteins | Signal transduction | Pathways | Sarcoplasmic reticulum | Rodents | Inhibition | Inositol 1,4,5-trisphosphate | Contractility | Muscles | RhoA protein | Sodium chloride | Muscle contraction | Rho-associated kinase | Cyclophosphamide | Inhibitors | Isoforms | Heparin | Index Medicus
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 10/2005, Volume 82, Issue 1, pp. 51 - 62
Chemokines are important mediators in immune responses and inflammatory processes. Calcitonin gene‐related peptide (CGRP) is produced in dorsal root ganglion... 
CCL2 | CXCL1 | calcitonin gene‐related peptide | dorsal root ganglion | CHEMOKINE RECEPTOR CXCR2 | PROTEIN-KINASE-C | CALCIUM-IONS | ALZHEIMERS-DISEASE | calcitonin gene-related peptide | DORSAL-ROOT GANGLION | NEUROSCIENCES | RAT SKIN | SIGNAL-TRANSDUCTION | NEUROPATHIC PAIN | OPIOID RECEPTORS | SUBSTANCE-P | Chemokines, CXC - immunology | Calcium - metabolism | Chemokine CCL2 - immunology | Nociceptors - physiology | Ganglia, Spinal - cytology | Dose-Response Relationship, Drug | GTP-Binding Protein alpha Subunits, Gi-Go - immunology | Drug Interactions | omega-Conotoxin GVIA - pharmacology | Time Factors | Chemokines, CXC - pharmacology | Calcitonin Gene-Related Peptide - metabolism | Ryanodine - pharmacology | Pertussis Toxin - pharmacology | Animals, Newborn | Neurons, Afferent - drug effects | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Pain Measurement - drug effects | Chelating Agents - pharmacology | Calcium Channel Blockers - pharmacology | GTP-Binding Protein alpha Subunits, Gi-Go - pharmacology | Antibodies - pharmacology | Pain Measurement - methods | Animals | Egtazic Acid - pharmacology | Analysis of Variance | Chemokine CCL2 - pharmacology | Intercellular Signaling Peptides and Proteins - pharmacology | Thapsigargin - pharmacology | Chemokine CXCL1 | Neurons, Afferent - metabolism | Radioimmunoassay - methods | Intercellular Signaling Peptides and Proteins - immunology | Index Medicus
Journal Article
Journal Article