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s-sulfhydration (123) 123
index medicus (108) 108
hydrogen sulfide (103) 103
animals (57) 57
oxidative stress (56) 56
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h2s (52) 52
biochemistry & molecular biology (50) 50
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hydrogen-sulfide (44) 44
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protein s-sulfhydration (35) 35
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equipment and supplies (28) 28
activation (27) 27
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cell biology (25) 25
pharmacology & pharmacy (22) 22
article (21) 21
hydrogen sulfide - chemistry (20) 20
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proteins (19) 19
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ischemia-reperfusion injury (18) 18
oxidation-reduction (18) 18
enzymes (17) 17
cystathionine gamma-lyase (16) 16
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sulfane sulfur (16) 16
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metabolism (15) 15
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living cells (14) 14
nitric oxide - metabolism (14) 14
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cells (13) 13
chemistry (13) 13
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endocrinology & metabolism (13) 13
nitric-oxide synthase (13) 13
persulfide (13) 13
plant sciences (13) 13
chemical biology (12) 12
cystathionine beta-synthase (12) 12
physiological aspects (12) 12
3-mercaptopyruvate sulfurtransferase (11) 11
analysis (11) 11
cystathionine-beta-synthase (11) 11
cysteine - metabolism (11) 11
cysteine persulfides (11) 11
expression (11) 11
gasotransmitter (11) 11
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physiology (11) 11
review (11) 11
sulfur (11) 11
thiols (11) 11
antioxidants (10) 10
biology (10) 10
in-vivo (10) 10
nf-kappa-b (10) 10
phosphorylation (10) 10
protein processing, post-translational (10) 10
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cell line (9) 9
cystathionine-gamma-lyase (9) 9
cysteine - chemistry (9) 9
mitochondria (9) 9
oxidative stress - drug effects (9) 9
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stress (9) 9
sulfide (9) 9
biochemistry (8) 8
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cystathionine beta-synthase - metabolism (7) 7
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health aspects (7) 7
homeostasis (7) 7
hydrogen ion concentration (7) 7
k-atp channels (7) 7
mechanism (7) 7
multidisciplinary sciences (7) 7
reactive oxygen species - metabolism (7) 7
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1. Full Text Detection of Protein S‐Sulfhydration by a Tag‐Switch Technique
by Zhang, Dehui and Macinkovic, Igor and Devarie‐Baez, Nelmi O and Pan, Jia and Park, Chung‐Min and Carroll, Kate S and Filipovic, Milos R and Xian, Ming
Angewandte Chemie International Edition, ISSN 1433-7851, 01/2014, Volume 53, Issue 2, pp. 575 - 581
Protein S‐sulfhydration (forming ‐S‐SH adducts from cysteine residues) is a newly defined oxidative posttranslational modification and plays an important role... 
hydrogen sulfide | thiols | signal transduction | protein S‐sulfhydration | tag‐switch | protein S-sulfhydration | tag-switch | MECHANISM | H2S | REACTIVITY | HYDROGEN-SULFIDE | CHEMISTRY, MULTIDISCIPLINARY | VASORELAXANT | BIOCHEMISTRY | CHEMISTRY | Biotin - chemistry | Human Umbilical Vein Endothelial Cells | Glutathione Peroxidase - chemistry | Jurkat Cells | Humans | Hydrogen Sulfide - chemistry | Sulfides - chemistry | Serum Albumin, Bovine - chemistry | Sulfhydryl Compounds - chemistry | Protein Processing, Post-Translational | Cysteine - chemistry | Microscopy, Fluorescence | Post-translational modification | Hydrogen sulfide | Cysteine | Thiols | Drugstores | Methods | Cystine | Proteins | Residues | Conjugates | Forming | Labels | Oxidation | Lead (metal)
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2. Full Text Hydrogen sulfide as a gasotransmitter
by Gadalla, Moataz M and Snyder, Solomon H
Journal of Neurochemistry, ISSN 0022-3042, 04/2010, Volume 113, Issue 1, pp. 14 - 26
J. Neurochem. (2010) 10.1111/j.1471‐4159.2010.06580.x Nitric oxide (NO) and carbon monoxide (CO) are well established as messenger molecules throughout the... 
cystathionase | S‐sulfhydration | EDRF | hydrogen sulfide | cystathionine γ‐lyase | cystathionine β‐synthase | Hydrogen sulfide | Cystathionine γ-lyase | Cystathionase | Cystathionine β-synthase | S-sulfhydration | cystathionine gamma-lyase | NITRIC-OXIDE SYNTHASE | K-ATP CHANNELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | MICE LACKING | S-NITROSYLATION | SMOOTH-MUSCLE | HEME OXYGENASE | CARBON-MONOXIDE | CHAIN FATTY-ACIDS | AMINO-ACID OXIDASE | CYSTATHIONINE-BETA-SYNTHASE | cystathionine beta-synthase | Hydrogen Sulfide - metabolism | Hydrogen Sulfide - pharmacology | Endothelium-Dependent Relaxing Factors - pharmacology | Humans | Hydrogen Sulfide - chemistry | Models, Molecular | Cystathionine gamma-Lyase - metabolism | Endothelium, Vascular - drug effects | Hypertension - drug therapy | Cystathionine beta-Synthase - metabolism | Carbon Monoxide - metabolism | Mice, Knockout | Animals | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Signal Transduction - physiology | Blood Pressure - drug effects | Mice | Nitric Oxide - metabolism | Cystathionine gamma-Lyase - deficiency | Enzymes | Neurosciences | Carbon monoxide | Endothelium-derived relaxing factors | Proteins | Nitric oxide | Chemical reactions | Biochemistry | cystathionine γ-lyase | KATP | cystathionine β-synthase | hydropersulfide | EDHF | GAPDH
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3. Full Text S‐sulfhydration of MEK1 leads to PARP‐1 activation and DNA damage repair
by Zhao, Kexin and Ju, YoungJun and Li, Shuangshuang and Altaany, Zaid and Wang, Rui and Yang, Guangdong
EMBO reports, ISSN 1469-221X, 07/2014, Volume 15, Issue 7, pp. 792 - 800
The repair of DNA damage is fundamental to normal cell development and replication. Hydrogen sulfide (H2S) is a novel gasotransmitter that has been reported to... 
H2S | PARP‐1 | S‐sulfhydration | MEK1 | PARP-1 | S-sulfhydration | CELLS | OXIDATIVE STRESS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTATHIONINE GAMMA-LYASE | HYDROGEN-SULFIDE | PROTECTS | CELL BIOLOGY | IN-VITRO | HYPERPOLARIZING FACTOR | ERK2 | DNA Damage - drug effects | DNA Repair - drug effects | Hydrogen Sulfide - pharmacology | Phosphorylation | Humans | MAP Kinase Kinase 1 - metabolism | Enzyme Activation - drug effects | MAP Kinase Signaling System | MAP Kinase Kinase 1 - genetics | Poly(ADP-ribose) Polymerases - metabolism | Models, Biological | Protein Processing, Post-Translational | Poly (ADP-Ribose) Polymerase-1 | Senescence | DNA repair | DNA damage | Deoxyribonucleic acid--DNA | Scientific Reports
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4. Full Text Hydrogen sulfide regulates the cytosolic/nuclear partitioning of glyceraldehyde-3-phosphate dehydrogenase by enhancing its nuclear localization
by Aroca, Angeles and Schneider, Markus and Scheibe, Renate and Gotor, Cecilia and Romero, Luis C
Plant and Cell Physiology, ISSN 0032-0781, 06/2017, Volume 58, Issue 6, pp. 983 - 992
Hydrogen sulfide is an important signaling molecule comparable with nitric oxide and hydrogen peroxide in plants. The underlying mechanism of its action is... 
des1 mutant | Arabidopsis | S -sulfhydration | Mass spectrometry | GFP fusion protein | Nuclei-enriched extract | TRANSLOCATION | ARABIDOPSIS-THALIANA | MECHANISMS | S-sulfhydration | AUTOPHAGY | PLANT SCIENCES | CELL BIOLOGY | CYSTEINE HOMEOSTASIS | REDOX REGULATION | NITRIC-OXIDE | PROTEINS | GAPDH | Green Fluorescent Proteins - metabolism | Hydrogen Sulfide - pharmacology | Arabidopsis - drug effects | Arabidopsis - enzymology | Cytosol - drug effects | Green Fluorescent Proteins - genetics | Cell Nucleus - enzymology | Arabidopsis Proteins - metabolism | Cytosol - enzymology | Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) - metabolism | Mass Spectrometry | Protein Processing, Post-Translational | Cell Nucleus - drug effects
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5. Full Text CDPKs enhance Cd tolerance through intensifying H2S signal in Arabidopsis thaliana
by Qiao, Zengjie and Qiao, Zengjie and Jing, Tao and Jing, Tao and Jin, Zhuping and Jin, Zhuping and Liang, Yali and Liang, Yali and Zhang, Liping and Zhang, Liping and Liu, Zhiqiang and Liu, Zhiqiang and Liu, Danmei and Liu, Danmei and Pei, Yanxi and Pei, Yanxi
Plant and Soil, ISSN 0032-079X, 1/2016, Volume 398, Issue 1, pp. 99 - 110
Hydrogen sulfide (H2S) acting as the third gasotransmitter following NO and CO has important physiological functions in both animals and plants. In plants, H2S... 
Life Sciences | Hydrogen sulfide | Cadmium | Protein S-sulfhydration | L-cysteine desulfhydrase | Calcium-dependent protein kinases | Glutathione persulfide | Plant Physiology | Ecology | Plant Sciences | Soil Science & Conservation | AGRONOMY | CADMIUM STRESS | MOLECULE | INVOLVEMENT | S-SULFHYDRATION | HYDROGEN-SULFIDE | PROTEIN-KINASES | PLANT SCIENCES | INDUCED HEAT TOLERANCE | SOIL SCIENCE | METABOLISM | ALUMINUM TOXICITY | ABSCISIC-ACID | Abiotic stress | Plant tolerance | Soil contamination
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6. Full Text Exogenous H2S enhances mice gastric smooth muscle tension through S‐sulfhydration of KV4.3, mediating the inhibition of the voltage‐dependent potassium current
by Liu, D.‐H and Huang, X and Meng, X.‐M and Zhang, C.‐M and Lu, H.‐L and Kim, Y.‐C and Xu, W.‐X
Neurogastroenterology & Motility, ISSN 1350-1925, 12/2014, Volume 26, Issue 12, pp. 1705 - 1716
Background Hydrogen sulfide (H2S) has been shown to have an excitatory effect on gastric motility, but the underlying molecular mechanism is unclear. In this... 
gastrointestinal motility | H2S | S‐sulfhydration | voltage‐dependent potassium current | KV4.3 | S | H | 4.3 | Gastrointestinal motility | K | S-sulfhydration | Voltage-dependent potassium current | Proteins | Hydrogen sulfide | Smooth muscle | Biotin | Potassium | Rodents
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7. Full Text Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy
by Meng, Guoliang and Xiao, Yujiao and Ma, Yan and Tang, Xin and Xie, Liping and Liu, Jieqiong and Gu, Yue and Yu, Ying and Park, Chung‐Min and Xian, Ming and Wang, Xin and Ferro, Albert and Wang, Rui and Moore, Philip K and Zhang, Zhiren and Wang, Hong and Han, Yi and Ji, Yong
Journal of the American Heart Association, ISSN 2047-9980, 09/2016, Volume 5, Issue 9, p. n/a
Background Hydrogen sulfide (H2S) is a gasotransmitter that regulates multiple cardiovascular functions. Krüppel‐like factor 5 (KLF5) exerts diverse functions... 
Krüppel‐like factor 5 | myocardial hypertrophy | S‐sulfhydration | hydrogen sulfide | atrial natriuretic peptide | specificity protein 1 | Hydrogen sulfide | Krüppel-like factor 5 | Atrial natriuretic peptide | S-sulfhydration | Myocardial hypertrophy | Specificity protein 1 | GASOTRANSMITTER | FIBROSIS | CELLS | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | SPONTANEOUSLY HYPERTENSIVE-RATS | H2S | KLF5/BTEB2 | Kruppel-like factor 5 | FAMILY | GYY4137 | CARDIAC-HYPERTROPHY | Hydrogen Sulfide - metabolism | Humans | Transcriptional Activation - drug effects | Angiotensin II - blood | Atrial Natriuretic Factor - drug effects | Cystathionine gamma-Lyase - metabolism | Male | Sp1 Transcription Factor - metabolism | RNA, Messenger - metabolism | Organothiophosphorus Compounds - pharmacology | Case-Control Studies | Kruppel-Like Transcription Factors - metabolism | Myocardium - metabolism | Platelet-Derived Growth Factor - drug effects | Kruppel-Like Transcription Factors - drug effects | RNA, Messenger - drug effects | Animals, Newborn | Rats, Inbred SHR | Atrial Natriuretic Factor - metabolism | Morpholines - pharmacology | Rats | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Platelet-Derived Growth Factor - metabolism | Animals | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - metabolism | Cardiomegaly - genetics | Kruppel-Like Transcription Factors - genetics | Cardiomegaly - metabolism
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8. Full Text H 2 S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells
by Ju, Youngjun and Untereiner, Ashley and Wu, Lingyun and Yang, Guangdong
Biochimica et Biophysica Acta - General Subjects, ISSN 0304-4165, 11/2015, Volume 1850, Issue 11, pp. 2293 - 2303
Background Cystathionine gamma-lyase (CSE)-derived hydrogen sulfide (H 2 S) possesses diverse roles in the liver, affecting lipoprotein synthesis, insulin... 
CSE | H 2 S | S-sulfhydration | Gluconeogenesis
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9. Full Text Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems
by Lin, Vivian S and Chen, Wei and Xian, Ming and Chang, Christopher J
Chemical Society Reviews, ISSN 0306-0012, 2015, Volume 44, Issue 14, pp. 4596 - 4618
Hydrogen sulfide (H2S), a gaseous species produced by both bacteria and higher eukaryotic organisms, including mammalian vertebrates, has attracted attention... 
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10. Full Text A new H2S-specific near-infrared fluorescence-enhanced probe that can visualize the H2S level in colorectal cancer cells in mice
by Zhang, K and Zhang, J and Xi, Z and Li, LY and Gu, XX and Zhang, QZ and Yi, L
CHEMICAL SCIENCE, ISSN 2041-6520, 04/2017, Volume 8, Issue 4, pp. 2776 - 2781
Near-infrared (NIR) fluorescence-based sensors capable of selective detection of H2S in vivo would be useful tools to understand the mechanisms of diseases. A... 
FAST-RESPONSE | SYNTHASE | THIOLYSIS | GLUTATHIONE | IN-VIVO | MITOCHONDRIA | S-SULFHYDRATION | SELECTIVE DETECTION | CHEMISTRY, MULTIDISCIPLINARY | ENDOGENOUS HYDROGEN-SULFIDE | LIVING CELLS
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11. Full Text Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems
by Lin, Vivian S and Chen, Wei and Xian, Ming and Chang, Christopher J
Chemical Society Reviews, ISSN 0306-0012, 7/2015, Volume 44, Issue 14, pp. 4596 - 4618
Hydrogen sulfide (H 2 S), a gaseous species produced by both bacteria and higher eukaryotic organisms, including mammalian vertebrates, has attracted attention... 
TURN-ON PROBE | AMINO-ACID-METABOLISM | PROTEIN S-SULFHYDRATION | SULFANE SULFUR | LARGE EMISSION SHIFT | CYSTATHIONINE BETA-SYNTHASE | SELECTIVE DETECTION | CHEMISTRY, MULTIDISCIPLINARY | RATIOMETRIC FLUORESCENT-PROBE | LIVING CELLS | AQUEOUS-SOLUTION | Hydrogen Sulfide - analysis | Molecular Imaging - methods | Humans | Fluorescent Dyes
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12. Full Text Hydrogen sulfide-based therapeutics: Exploiting a unique but ubiquitous gasotransmitter
by Wallace, John L and Wang, Rui
Nature Reviews Drug Discovery, ISSN 1474-1776, 05/2015, Volume 14, Issue 5, pp. 329 - 345
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule throughout the body, contributing to many physiological and pathological... 
ISCHEMIA-REPERFUSION INJURY | PROTEIN S-SULFHYDRATION | AMINO-ACID-SEQUENCE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | K-ATP CHANNELS | NITRIC-OXIDE SYNTHASE | CYSTATHIONINE-GAMMA-LYASE | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | ENDOPLASMIC-RETICULUM STRESS | NF-KAPPA-B | Hydrogen Sulfide - metabolism | Signal Transduction - physiology | Animals | Molecular Targeted Therapy | Humans | Gasotransmitters - metabolism | Hydrogen sulfide | Care and treatment | Health aspects | Patients | Standards | Index Medicus
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