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Nature Medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 256 - 263
The cytostatic deoxycytidine analog cytarabine (ara-C) is the most active agent available against acute myelogenous leukemia (AML). Together with... 
MEDICINE, RESEARCH & EXPERIMENTAL | CYTOSINE-ARABINOSIDE | CELLS | ARA-C SENSITIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | CELL BIOLOGY | IN-VITRO | DNA | CHRONIC LYMPHOCYTIC-LEUKEMIA | MUTATIONS | EXPRESSION | Cytarabine - pharmacology | Prognosis | Apoptosis - drug effects | Cytarabine - therapeutic use | Humans | Leukemia, Myeloid, Acute - metabolism | SAM Domain and HD Domain-Containing Protein 1 | Child, Preschool | Infant | Male | Viral Regulatory and Accessory Proteins - pharmacology | Molecular Targeted Therapy | Monomeric GTP-Binding Proteins - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Antimetabolites, Antineoplastic - pharmacology | Female | Child | Disease Models, Animal | Arabinofuranosylcytosine Triphosphate - metabolism | Antimetabolites, Antineoplastic - therapeutic use | Animals | Monomeric GTP-Binding Proteins - metabolism | Adolescent | Aged | Mice | In Vitro Techniques | Cellular proteins | Molecular targeted therapy | Care and treatment | Cytarabine | Patient outcomes | Drug interactions | Innovations | Development and progression | Genetic aspects | Blood diseases | Health aspects | Biomarkers | Cytotoxicity | Chemotherapy | Gene expression | Leukemia | Biological Sciences | Clinical Medicine | Naturvetenskap | Medical and Health Sciences | Hematology | Hematologi | Medicin och hälsovetenskap | Biologiska vetenskaper | Natural Sciences | Klinisk medicin
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 250 - 255
Journal Article
Nature, ISSN 0028-0836, 06/2011, Volume 474, Issue 7353, pp. 654 - 657
Journal Article
Journal Article
Journal Article
Virology, ISSN 0042-6822, 2012, Volume 436, Issue 1, pp. 81 - 90
Abstract The human SAMHD1 protein is a novel retroviral restriction factor expressed in myeloid cells. Previous work has correlated the deoxynucleotide... 
Infectious Disease | HIV-1 | Restriction | HD domain | dNTPase | SAMHD1 | RNA binding | DNTPase | HIV-1 RESTRICTION | DENDRITIC CELLS | PARTICLES | MACROPHAGE INFECTION | NUCLEAR-LOCALIZATION | VPX PROTEIN | VIROLOGY | SIMIAN IMMUNODEFICIENCY VIRUS | MUTATIONS | PRIMATE LENTIVIRUSES | TRIM5-ALPHA | RNA-Binding Proteins - genetics | Retroviridae Infections - virology | Humans | SAM Domain and HD Domain-Containing Protein 1 | Green Fluorescent Proteins - genetics | Immunodeficiency Virus, Bovine - physiology | Leukemia Virus, Murine - physiology | Simian Immunodeficiency Virus - genetics | HIV-1 - physiology | Macrophages - virology | Retroviridae - genetics | U937 Cells | HEK293 Cells | HIV-2 - physiology | HIV-2 - genetics | Protein Interaction Domains and Motifs | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | Immunodeficiency Virus, Feline - physiology | Dendritic Cells - virology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Cell Line | Retroviridae - physiology | HIV-1 - genetics | Monomeric GTP-Binding Proteins - antagonists & inhibitors | Infectious Anemia Virus, Equine - physiology | Monomeric GTP-Binding Proteins - metabolism | Monomeric GTP-Binding Proteins - chemistry | Simian Immunodeficiency Virus - metabolism | HeLa Cells | RNA-Binding Proteins - metabolism | Oligomers | Enzymes | RNA | Leukemia | High-definition television | HIV (Viruses) | Health aspects | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue 7377, pp. 379 - 382
Journal Article