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Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 11/2010, Volume 18, Issue 22, pp. 7940 - 7947
As part of our search for botanical sources of SARS-CoV 3CL inhibitors, we selected Torreya nucifera, which is traditionally used as a medicinal plant in Asia.... 
Amentoflavone | Biflavonoid | SARS-CoV 3CL | Torreya nucifera
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2013, Volume 21, Issue 13, pp. 3730 - 3737
Phlorotannins have been isolated and are the first of their type showing competitively inhibitory activity toward SARS-CoV 3CLpro. Dieckol showed the most... 
Phlorotannin | Eckol | Ecklonia cava | SARS-CoV | Dieckol
Journal Article
Microbes and Infection, ISSN 1286-4579, 2013, Volume 15, Issue 8-9, pp. 625 - 629
Middle East respiratory syndrome coronavirus (MERS-CoV), a novel human coronavirus that caused outbreaks of a SARS-like illness in the Middle East, is now... 
Coronavirus | SARS-CoV | Therapeutics | MERS-CoV | Vaccine | Source
Journal Article
Virology, ISSN 0042-6822, 02/2018, Volume 515, pp. 165 - 175
Severe acute respiratory syndrome coronavirus (SARS-CoV) is an inefficient inducer of interferon (IFN) response. It expresses various proteins that effectively... 
ORF8 | IFN antagonist | IRF3 | Ubiquitin-dependent degradation | SARS-CoV
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2013, Volume 3
The identification of a novel beta coronavirus, nCoV, as the causative agent of severe respiratory illness in humans originating in Saudi Arabia, Qatar and... 
GAMMA | SARS-COV INFECTION | SYNERGISTICALLY INHIBIT | MAJOR OUTBREAK | VIRUS | EPITHELIAL CALU-3 CELLS | PHARMACOKINETICS | MULTIDISCIPLINARY SCIENCES | ACUTE RESPIRATORY SYNDROME | FUNCTIONAL RECEPTOR | HONG-KONG
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2020, Volume 35, Issue 1, pp. 145 - 151
There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting... 
SARS-CoV 3CLpro | FRET | flavonoid | SARS-CoV | inhibitory compounds | sars-cov 3clpro | sars-cov | fret
Journal Article
Antiviral Research, ISSN 0166-3542, 05/2017, Volume 141, pp. 101 - 106
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory illness with fever, cough and shortness of breath. Up to date, it has... 
Picornavirus | 3C-like protease | MERS-CoV | Coronavirus | Peptidomimetic inhibitor | SARS-CoV
Journal Article
JOURNAL OF VIROLOGY, ISSN 0022-538X, 11/2019, Volume 93, Issue 22
Enteric viruses exploit bacterial components, including lipopolysaccharides (LPS) and peptidoglycan (PG), to facilitate infection in humans. Because of their... 
surfactin | VIRUS | PARTICLES | MECHANISM | SARS-CoV | BLOCK | coronavirus | cyclic lipopeptide | MERS-CoV | MICROBIOTA | microbiome | PATHOGENESIS | BIOSURFACTANT | VIROLOGY | DYNAMICS | MICE
Journal Article
Biochemistry and Cell Biology, ISSN 0829-8211, 2019, Volume 97, Issue 6, pp. 758 - 766
Severe acute respiratory syndrome coronavirus nonstructural protein 1 (nsp1) is a key factor in virus-induced down-regulation of host gene expression. In... 
Nup93 | NLS | SLN | nsp1 | SARS-CoV | nuclear pore complex | complexe des pores nucléaires | SRAS-CoV | immunofluorescence
Journal Article
PLOS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9
Virus like particles (VLPs) produced by the expression of viral structural proteins can serve as versatile nanovectors or potential vaccine candidates. In this... 
SEQUENCE-ANALYSIS | SPIKE PROTEINS | STRUCTURAL PROTEINS | ADENOVIRUS DODECAHEDRON | MULTIDISCIPLINARY SCIENCES | SARS-COV | PURIFICATION | VIRUS-LIKE PARTICLES | SIZE-EXCLUSION CHROMATOGRAPHY | EXPRESSION SYSTEM | MEMBRANE-PROTEIN GENE
Journal Article
Methods in Enzymology, ISSN 0076-6879, 2019, Volume 618, p. 357
Protein (poly-)ubiquitination is a posttranslational modification that plays a key role in almost all cellular processes. It involves the installment of either... 
Deubiquitinating enzymes | MERS-CoV PLpro | SARS-CoV PLpro | (di)ubiquitin-based probes | Activity-based probes | Viral DUBs | Ub linkage specificity | Ubl-specific proteases | Ub–Ubl crosstalk
Journal Article
Journal of Virology, ISSN 0022-538X, 03/2019, Volume 93, Issue 6
Transmembrane serine protease TMPRSS2 activates the spike protein of highly pathogenic human coronaviruses such as severe acute respiratory syndrome-related... 
Animal model | Immunopathology | TMPRSS2 | MERS-CoV | SARS-CoV | ENTRY | SERINE PROTEASES | PROTEOLYTIC ACTIVATION | SARS | IDENTIFICATION | ACUTE RESPIRATORY SYNDROME | immunopathology | REPLICATION | VIROLOGY | INFLUENZA-A VIRUS | SPIKE PROTEIN | MICE | animal model
Journal Article