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NMR in Biomedicine, ISSN 0952-3480, 09/2016, Volume 29, Issue 9, pp. 1316 - 1334
Presently, three major MR vendors provide commercial 7‐T units for clinical research under ethical permission, with the number of operating 7‐T systems having... 
7‐T neurological applications | 7‐T whole‐body applications | comparison studies 7 T versus 3 T | 7 T | clinical 7‐T studies | ultrahigh‐field MR | 7‐T multi‐nuclear spectroscopy and imaging | improved diagnosis for patients at 7 T | 7-T multi-nuclear spectroscopy and imaging | Ultrahigh-field MR | 7-T whole-body applications | 7-T neurological applications | Improved diagnosis for patients at 7T | Clinical 7-T studies | Comparison studies 7T versus 3T | clinical 7-T studies | improved diagnosis for patients at 7 T | 7 T | comparison studies 7 T versus 3 T | ultrahigh-field MR | SATURATION-TRANSFER CEST | improved diagnosis for patients at 7T | PROTON CHEMICAL-EXCHANGE | INVERSION-RECOVERY MRI | VIVO P-31 MRS | 7 T MRI | HUMAN CALF MUSCLE | HUMAN ARTICULAR-CARTILAGE | BIOPHYSICS | SPECTROSCOPY | comparison studies 7T versus 3T | IN-VIVO | MAGNETIC-RESONANCE | 7T | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | AUTOLOGOUS CHONDROCYTE TRANSPLANTATION | Neuroimaging - methods | Reproducibility of Results | Magnetic Resonance Spectroscopy - methods | Humans | Image Interpretation, Computer-Assisted - methods | Imaging, Three-Dimensional - methods | Magnetic Resonance Imaging - methods | Molecular Imaging - methods | Radiation Dosage | Evidence-Based Medicine | Animals | Sensitivity and Specificity | Image Enhancement - methods | Magnetic Fields
Journal Article
Journal Article
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1824, pp. 49 - 66
Saturation transfer difference (STD) NMR has emerged as one of the key technologies in lead optimization during drug design. Unlike most biophysical assays... 
Epitope mapping | Screening | Nuclear magnetic resonance spectroscopy | Saturation transfer difference NMR | Ligand-based NMR
Journal Article
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 04/2016, Volume 22, Issue 17, pp. 5858 - 5862
Inhibitors of the p53‐MDM2 protein–protein interaction are emerging as a new and validated approach to treating cancer. Herein, we describe the synthesis and... 
saturation-transfer difference NMR spectroscopy | cancer | NMR spectroscopy | p53–MDM2 | molecular modelling | proteins
Journal Article
FEBS Letters, ISSN 0014-5793, 04/2016, Volume 590, Issue 7, pp. 943 - 953
O ‐acetylserine sulfhydrylase ( OASS ), the enzyme catalysing the last step of cysteine biosynthesis in bacteria, is involved in antibiotic resistance and... 
NMR | cysteine synthase | cysteine biosynthesis | Saturation Transfer Difference | Saturation Transfer Difference NMR | MYCOBACTERIUM-TUBERCULOSIS | SERINE ACETYLTRANSFERASE | LIGAND-BINDING | ACTIVE-SITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | CELL BIOLOGY | BIOPHYSICS | CYSTEINE SYNTHASE COMPLEX | PURIFICATION | BIENZYME COMPLEX-FORMATION | SALMONELLA-TYPHIMURIUM | DATURA-INNOXIA | Epitope Mapping | Bacterial Proteins - chemistry | Isoenzymes - chemistry | Peptide Library | Antimicrobial Cationic Peptides - metabolism | Cysteine Synthase - genetics | Cysteine Synthase - metabolism | Cysteine Synthase - chemistry | Isoenzymes - metabolism | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Haemophilus influenzae - enzymology | Nuclear Magnetic Resonance, Biomolecular | Protein Interaction Domains and Motifs | Salmonella typhimurium - enzymology | Binding Sites | Oligopeptides - chemistry | Cysteine Synthase - antagonists & inhibitors | Recombinant Proteins - metabolism | Bacterial Proteins - antagonists & inhibitors | Enzyme Inhibitors - metabolism | Antimicrobial Cationic Peptides - chemistry | Isoenzymes - genetics | Antimicrobial Cationic Peptides - pharmacology | Bacterial Proteins - genetics | Enzyme Inhibitors - pharmacology | Models, Molecular | Recombinant Proteins - chemistry | Anti-Bacterial Agents - metabolism | Oligopeptides - metabolism | Hydrogen Bonding | Bacterial Proteins - metabolism | Protein Conformation | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Structural Homology, Protein | Oligopeptides - pharmacology | Isoenzymes - antagonists & inhibitors
Journal Article
Journal of Magnetic Resonance, ISSN 1090-7807, 11/2016, Volume 272, pp. 82 - 86
Measurement of Chemical Exchange Saturation Transfer (CEST) is providing tissue physiology dependent contrast, e.g. by looking at Amide and NOE (Nuclear... 
CEST contrast origin | NOE | Water content | Amide | CEST | correction | Gray matter | Water T | White matter | HUMAN BRAIN | MRI | BIOCHEMICAL RESEARCH METHODS | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | MAGNETIZATION-TRANSFER | PULSED STEADY-STATE | EXCHANGE SATURATION-TRANSFER | WATER SATURATION | RESONANCE | SPECTROSCOPY | IN-VIVO | Water T-1 correction | OPTIMIZATION | PROTON-TRANSFER
Journal Article
FRONTIERS IN CHEMISTRY, ISSN 2296-2646, 04/2019, Volume 7, p. 215
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 11/2016, Volume 31, Issue sup4, pp. 78 - 87
Journal Article
Journal Article
Physical chemistry chemical physics : PCCP, ISSN 1463-9076, 04/2018, Volume 20, Issue 14, pp. 9561 - 9573
Type 2 diabetes mellitus and Alzheimer's disease are characterized by the accumulation of fibrillar amyloid deposits consisting mainly of islet amyloid... 
Amino Acid Sequence | Islet Amyloid Polypeptide - chemistry | Magnetic Resonance Spectroscopy | Protein Aggregates - physiology | Humans | Protein Conformation | Amyloid beta-Peptides - chemistry | Kinetics | Chemical Sciences
Journal Article