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NATURE REVIEWS CANCER, ISSN 1474-175X, 08/2006, Volume 6, Issue 8, pp. 637 - 645
Metastasis follows the inappropriate activation of a genetic programme termed invasive growth, which is a physiological process that occurs during embryonic... 
EPITHELIAL-MESENCHYMAL TRANSITION | HUMAN BREAST-CARCINOMA | TUMOR PROGRESSION | ONCOLOGY | FACTOR SCATTER FACTOR | C-MET | BONE-MARROW | ACUTE MYELOID-LEUKEMIA | RECEPTOR TYROSINE KINASE | HGF RECEPTOR | FACTOR/SCATTER FACTOR
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 09/2017, Volume 58, Issue 9, pp. 1386 - 1394
The hepatocyte growth factor (HGF) binding antibody rilotumumab (AMG102) was modified for use as a 89Zr-based immuno-PET imaging agent to noninvasively... 
AMG102 | Hepatocyte growth factor | HGF | Rilotumumab | MET | Scatter factor | PET | Patient-derived xenograft | Index Medicus | rilotumumab | patient-derived xenograft | hepatocyte growth factor | scatter factor | Oncology
Journal Article
The Oncologist, ISSN 1083-7159, 08/2018, Volume 23, Issue 8, pp. 889 - e98
经验获取 • 由于脑肿瘤影像标准的不断发展以及磁共振影像评估的变化,以缓解率作为主要指标不够理想。未来有关抗血管生成药物的研究应使用总生存期。 • 在界定不良事件的临床意义时,应考虑疾病的预期毒性。例如,血管血栓栓塞事件在脑肿瘤患者中常见,做安全性分析时不应归因于研究药物。 摘要 背景 .... 
TRIAL | ONCOLOGY | FACTOR SCATTER FACTOR | LOMUSTINE | SINGLE-AGENT BEVACIZUMAB | FACTOR EXPRESSION | IRINOTECAN | MET | PROGRESSION | ENDOTHELIAL GROWTH-FACTOR | Clinical Trial Results
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 09/2016, Volume 34, Issue 25, pp. 3005 - 3013
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 05/2019, Volume 476, Issue 10, pp. 1419 - 1431
Phosphatase of regenerating liver (PRL) is overexpressed in metastatic cancers and actively drives their malignant progression. Many studies on cultured cancer... 
FACTOR-RECEPTOR | SCATTER FACTOR | METASTASIS | CELL-MIGRATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | MOLECULAR-CLONING | PRL-3 | CANCER | PROTEIN-TYROSINE-PHOSPHATASE | SOMATIC MUTATIONS
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 9, pp. 1007 - 1018
Summary Background Dysregulation of the hepatocyte growth factor (HGF)/MET pathway promotes tumour growth and metastasis. Rilotumumab is a fully human,... 
Hematology, Oncology and Palliative Medicine | ADVANCED SOLID TUMORS | CANCER-PATIENTS | AMPLIFICATION | ONCOLOGY | HEPATOCYTE GROWTH-FACTOR | C-MET | MONOCLONAL-ANTIBODY | CIRCULATING LEVEL | AMG 102 | CARCINOMA | FACTOR/SCATTER FACTOR | Confidence Intervals | Adenocarcinoma - pathology | Esophagogastric Junction - drug effects | Prognosis | Capecitabine | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Stomach Neoplasms - pathology | Dose-Response Relationship, Drug | Fluorouracil - therapeutic use | Deoxycytidine - therapeutic use | Fluorouracil - adverse effects | Neoplasm Invasiveness - pathology | Adult | Deoxycytidine - adverse effects | Female | Double-Blind Method | Drug Administration Schedule | Fluorouracil - analogs & derivatives | Proportional Hazards Models | Esophagogastric Junction - pathology | Survival Rate | Treatment Outcome | Stomach Neoplasms - drug therapy | Adenocarcinoma - drug therapy | Disease-Free Survival | Maximum Tolerated Dose | Cisplatin - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Cisplatin - adverse effects | Epirubicin - therapeutic use | Aged | Neoplasm Staging | Stomach Neoplasms - mortality | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Epirubicin - adverse effects | Monoclonal antibodies | Anthracyclines | Index Medicus
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 04/2002, Volume 62, Issue 7, pp. 2064 - 2071
Hepatocyte growth factor (HGF) and Wnt signaling pathways have been shown to be important in embryogenesis and carcinogenesis. The aim of this study was to... 
ACTIVATION | SCATTER FACTOR | TYROSINE PHOSPHORYLATION | RAT | ONCOLOGY | C-MET | RECEPTOR | CELL-CELL ADHESION | EXPRESSION | CARCINOMA | ASSOCIATION
Journal Article
Cancer Research, ISSN 0008-5472, 10/2009, Volume 69, Issue 19, pp. 7569 - 7576
Journal Article
Cancer Research, ISSN 0008-5472, 12/2010, Volume 70, Issue 24, pp. 10090 - 10100
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2005, Volume 23, Issue 34, pp. 8774 - 8785
Purpose Pulmonary large-cell neuroendocrine carcinoma (LCNEC) is a relatively uncommon, high-grade neuroendocrine tumor sharing several features with... 
ADJUVANT CHEMOTHERAPY | RETINOBLASTOMA PROTEIN | CANCER CELLS | ONCOLOGY | FACTOR SCATTER FACTOR | PROTEIN EXPRESSION | GENE-EXPRESSION | GROWTH-FACTOR RECEPTORS | C-KIT | PHASE-II | THERAPEUTIC INHIBITION
Journal Article
Cancer Research, ISSN 0008-5472, 05/2007, Volume 67, Issue 9, pp. 4408 - 4417
Journal Article