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Pain, ISSN 0304-3959, 10/2012, Volume 153, Issue 10, pp. 2017 - 2030
A vast diversity of salient cues is sensed by numerous classes of primary sensory neurons, defined by specific neuropeptides, ion channels, or cytoskeletal... 
Nociceptive | C fiber | tdTomato | VGSC | Scn10a | C-LTM
Journal Article
CARDIOVASCULAR RESEARCH, ISSN 0008-6363, 06/2015, Volume 106, Issue 3, pp. 520 - 529
Aims Brugada syndrome(BrS) remains genetically heterogeneous and is associated with slowed cardiac conduction. We aimed to identify genetic variation in BrS... 
CARDIAC & CARDIOVASCULAR SYSTEMS | ARRHYTHMIA SYNDROMES | Brugada syndrome | Rare variants | ATRIAL-FIBRILLATION | SCN10A | PR INTERVAL | SEQUENCE | Genetics | CONDUCTION | QRS duration | CHANNELS | HEART-RATE | MUTATIONS | ASSOCIATION | DURATION
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 01/2019, Volume 27, Issue 1, pp. 230 - 239
The voltage gated sodium channel Na 1.8 has been postulated to play a key role in the transmission of pain signals. Core hopping from our previously reported... 
NaV1.8 | SCN10A | PF-06305591 | Benzimidazole | Voltage gated sodium channel | Inflammatory pain | Neuropathic pain | Na | 1.8 | Index Medicus
Journal Article
PAIN, ISSN 0304-3959, 10/2012, Volume 153, Issue 10, pp. 2017 - 2030
A vast diversity of salient cues is sensed by numerous classes of primary sensory neurons, defined by specific neuropeptides, ion channels, or cytoskeletal... 
GENE-RELATED PEPTIDE | C fiber | PRIMARY AFFERENT NEURONS | tdTomato | DRG NEURONS | VGSC | SPINAL-CORD | Scn10a | DORSAL-ROOT GANGLION | NEUROSCIENCES | CLINICAL NEUROLOGY | Nociceptive | NEUROPATHIC PAIN | ANESTHESIOLOGY | INFLAMMATORY PAIN | PRIMARY SENSORY NEURONS | RESISTANT SODIUM-CHANNELS | SUBSTANCE-P | C-LTM
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2018, Volume 114, Issue 13, pp. 1691 - 1693
Journal Article
Journal of Neurology Neurosurgery and Psychiatry, ISSN 0022-3050, 05/2014, Volume 85, Issue 5, pp. 499 - 505
Objective Painful small fibre neuropathy (SFN) represents a significant public health problem, with no cause apparent in one-half of cases (termed idiopathic,... 
SURGERY | RAT | GANGLION NEURONS | PSYCHIATRY | NOCICEPTORS | GATED SODIUM-CHANNEL | SENSORY NEURONS | CLINICAL NEUROLOGY | SCN10A | EXTREME PAIN DISORDER | EXPRESSION | NA+ CURRENT | SARCOIDOSIS
Journal Article
NEUROLOGY, ISSN 0028-3878, 02/2016, Volume 86, Issue 5, pp. 473 - 483
The Na(V)1.8 sodium channel, encoded by gene SCN10A, was initially termed sensory neuron-specific (SNS) due to prominent expression in primary sensory neurons... 
PURKINJE NEURONS | GENETIC-VARIATION | NA-V 1.8 | CEREBELLAR DYSFUNCTION | SCN10A | VARIANTS | ROOT GANGLION NEURONS | PAROXYSMAL DYSARTHRIA | OSCILLATIONS | UP-REGULATION | CLINICAL NEUROLOGY
Journal Article
Circulation research, ISSN 0009-7330, 2012, Volume 111, Issue 3, pp. 333 - 343
Rationale: The SCN10A gene encodes the neuronal sodium channel isoform Na(V)1.8. Several recent genome-wide association studies have linked SCN10A to PR... 
cardiac electrophysiology | COMMON VARIANTS | CARDIAC & CARDIOVASCULAR SYSTEMS | autonomic nervous system | RAT | GATED SODIUM-CHANNELS | DRG NEURONS | SINOATRIAL NODE | SENSORY NEURONS | TETRODOTOXIN-RESISTANT | SCN10A | PR INTERVAL | sodium channels | PERIPHERAL VASCULAR DISEASE | HEART-RATE | QRS DURATION | HEMATOLOGY
Journal Article
Pain, ISSN 0304-3959, 4/2016, Volume 157, Issue 4, pp. 879 - 891
High frequency spontaneous firing in myelinated sensory neurons plays a key role in initiating pain behaviors in several different models, including the... 
Nav1.6 | ectopic activity | resurgent current | sodium channel | Scn10a | Scn4b | radicular pain | NaVβ4
Journal Article
Journal of Electrocardiology, ISSN 0022-0736, 09/2018, Volume 51, Issue 5, pp. 809 - 813
Sudden cardiac death is an important cause of mortality in the general population. It represents an important challenge for clinicians, often being the only... 
Sudden cardiac death | Next generation sequencing | SCN10A | Cardiovascular disease | Mutation | Genes | Genomics | Mortality
Journal Article
CARDIOVASCULAR RESEARCH, ISSN 0008-6363, 06/2015, Volume 106, Issue 3, pp. 351 - 352
This editorial refers to 'Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study' by E.R.... 
SCN10A | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN CARDIAC DEATH | CHANNELS | MUTATIONS
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 01/2019, Volume 27, Issue 1, pp. 230 - 239
The voltage gated sodium channel Na(V)1.8 has been postulated to play a key role in the transmission of pain signals. Core hopping from our previously reported... 
CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | Neuropathic pain | SCN10A | POTENT | PF-06305591 | Benzimidazole | Na(V)1.8 | INHIBITORS | MUTATIONS | Voltage gated sodium channel | Inflammatory pain
Journal Article
JOURNAL OF THE AMERICAN HEART ASSOCIATION, ISSN 2047-9980, 11/2016, Volume 5, Issue 11
Background- Ganglionated plexus have been developed as additional ablation targets to improve the outcome of atrial fibrillation (AF) besides pulmonary vein... 
CARDIAC & CARDIOVASCULAR SYSTEMS | BRUGADA SYNDROME | GANGLIONATED PLEXI | GATED SODIUM-CHANNEL | PULMONARY VEIN ISOLATION | GENETIC-VARIATION | atrial fibrillation | SCN10A | electrophysiology | RARE VARIANTS | ganglionated plexus | MODULATE | HEART-RATE | AUTONOMIC NERVE-STIMULATION | SCN10A GENE | Na(v)1.8
Journal Article
Cardiovascular research, ISSN 0008-6363, 2015, Volume 106, Issue 3, pp. 520 - 529
Journal Article
Pflugers Archiv : European journal of physiology, ISSN 0031-6768, 1/2016, Volume 468, Issue 1, pp. 99 - 110
Dorsal root ganglia (DRG) neurons are important relay stations between the periphery and the central nervous system and are essential for somatosensory... 
Aging | Radical stress | Reactive oxygen species | Sodium channel | Pain | Scn10a
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 08/2019, Volume 17, Issue 1, pp. 287 - 287
Experimental studies suggest that testosterone reduces the nociceptive response after inflammatory and neuropathic stimuli, however the underlying mechanisms... 
Pain, Postoperative | Testosterone | Models | Flutamide | Gene expression | Genes | Index Medicus | Gender influence | Postoperative pain | NAV1.7 and NAV1.8 voltage-gated sodium channels | Scn9a e Scn10a gene expression
Journal Article
Circulation, ISSN 0009-7322, 04/2013, Volume 127, Issue 13, pp. 1377 - 1385
Journal Article
JOURNAL OF ELECTROCARDIOLOGY, ISSN 0022-0736, 09/2018, Volume 51, Issue 5, pp. 809 - 813
Introduction: Sudden cardiac death is an important cause of mortality in the general population. It represents an important challenge for clinicians, often... 
SCN10A | CARDIAC & CARDIOVASCULAR SYSTEMS | BRUGADA SYNDROME | DATABASE | CHANNEL | EARLY REPOLARIZATION | ISCHEMIA | Sudden cardiac death | Next generation sequencing
Journal Article
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