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2006, ISBN 9783527310951, xviii, 368
Edited by one of the leading experts in the field, this book fills the need for a book presenting the most important methods for high-throughput screenings and... 
Enzymes | Analysis | Life Sciences | Science | Biochemistry
Book
Journal Article
04/2016, ISBN 9781119053248, 1048
As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and... 
Drugs | Toxicology | Toxicity testing | High throughput screening (Drug development)
eBook
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1821, pp. 165 - 175
We describe a high-throughput screening (HTS)-compatible method for detecting GTPase exchange factor (GEF) activity based on stimulation of GDP formation by... 
High-throughput | Fluorescence polarization | GEF assay | Homogeneous | Multiwell | GEF inhibitor
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 01/2018, Volume 13, Issue 1, pp. 36 - 44
Pan-Assay Interference Compounds (PAINS) are very familiar to medicinal chemists who have spent time fruitlessly trying to optimize these nonprogressible... 
LIBRARIES | AGONY | DESIGN | ECSTASY | FALSE POSITIVES | HTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FILTERS | CHEMICAL PROBES | SCREENING METHOD | DISCOVERY | Drug Evaluation, Preclinical - methods | Databases, Chemical | Structure-Activity Relationship | Reviews
Journal Article
2012, 2nd ed., ISBN 9780199744206, xvi, 560
Because medicine can preserve life, restore health and maintain the body's functions, it is widely acknowledged as a basic good that just societies should... 
Social medicine | Moral and ethical aspects | Social justice | Medical economics | Medical ethics | Right to health | Medicine: General Issues | moral philosophy | Health care | Medicine | Brain dead | Medical malpractice | Medical resources | Newborn screening | Genetics | Neurological injury | Chronically ill
Book
F1000Research, ISSN 2046-1402, 2017, Volume 6, p. 1505
A large-scale statistical analysis of hit rates of extensively assayed compounds is presented to provide a basis for a further assessment of assay interference... 
Small Molecule Chemistry | Assay frequency | Assay interference | Hit rate distribution | Active compounds | Statistical analysis | Biological screening data
Journal Article
Journal Article
Environmental and Molecular Mutagenesis, ISSN 0893-6692, 04/2018, Volume 59, Issue 3, pp. 211 - 222
Journal Article