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Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 803 - 818
Among the 11 members of the secreted phospholipase A (sPLA ) family, group IID, IIE, IIF and III sPLA s (sPLA -IID, -IIE, -IIF and -III, respectively) are... 
Lipidomics | Pathophysiological function | Knockout mice | Secreted phospholipase A | Lipid-metabolic pathways | Transgenic mice
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 803 - 818
Among the 11 members of the secreted phospholipase A (sPLA ) family, group IID, IIE, IIF and III sPLA s (sPLA -IID, -IIE, -IIF and -III, respectively) are... 
Lipidomics | Pathophysiological function | Knockout mice | Secreted phospholipase A2 | Transgenic mice | Lipid-metabolic pathways
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 803 - 818
Journal Article
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 10/2000, Volume 1488, Issue 1-2, pp. 1 - 19
The phospholipase A (PLA ) superfamily consists of a broad range of enzymes defined by their ability to catalyze the hydrolysis of the middle (sn-2) ester bond... 
Calcium-independent phospholipase A | Platelet activating factor acetylhydrolase | Secreted phospholipase A | Arachidonic acid | Phospholipase B | Cytosolic phospholipase A
Journal Article
Methods in Enzymology, ISSN 0076-6879, 2017, Volume 583, pp. 101 - 117
The secreted phospholipase A (sPLA ) family contains 10 catalytically active isoforms. Current in vitro biochemical studies have shown that individual sPLA s... 
Secreted phospholipase A | Knockout mouse | Lysophospholipid | Phospholipid | Polyunsaturated fatty acid | Lipidomics | Transgenic mouse | Arachidonic acid | Docosahexaenoic acid | Mass spectrometry
Journal Article
BIOCHIMIE, ISSN 0300-9084, 12/2014, Volume 107, pp. 105 - 113
Within the phospholipase A(2) (PLA(2)) superfamily, secreted PLA(2) (sPLA(2)) enzymes comprise the largest family that contains 11 to 12 mammalian isoforms... 
M-TYPE RECEPTOR | GROUP-V | MAST-CELL MATURATION | GROUP-X | Prostaglandin | BIOCHEMISTRY & MOLECULAR BIOLOGY | Phospholipid | RECOMBINANT EXPRESSION | LIPID MEDIATORS | DEFICIENT MICE | DIET-INDUCED OBESITY | PATHOGENIC ROLE | Lipid mediator | ALLERGIC PULMONARY INFLAMMATION | Secreted phospholipase A | Fatty acid
Journal Article
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 789 - 802
Among all members of the secreted phospholipase A (sPLA ) family, group IIA sPLA (sPLA -IIA) is possibly the most studied enzyme. Since its discovery, many... 
Inflammation | Infectious diseases | Secreted phospholipase A | Platelets | Microbiome
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 819 - 826
Group V Phospholipase A(2) (Pla2g5) is a member of the PLA(2) family of lipid-generating enzymes. It is expressed in immune and non-immune cell types and is... 
GROUP-X | HUMAN NEUTROPHILS | CYSTEINYL LEUKOTRIENE SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Eicosanoids | linoleic acid | LOW-MOLECULAR-WEIGHT | RECOMBINANT EXPRESSION | INNATE LYMPHOID-CELLS | Macrophages | IL-33 | Asthma | Free fatty acids | CELL BIOLOGY | BIOPHYSICS | ARACHIDONIC-ACID MOBILIZATION | GROUP IVA | SECRETED PHOSPHOLIPASE-A | GROUP-II
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 789 - 802
Among all members of the secreted phospholipase A(2) (sPLA(2)) family, group IIA sPLA(2) (sPLA(2)-IIA) is possibly the most studied enzyme. Since its... 
ARACHIDONIC-ACID RELEASE | MAJOR PHYSIOLOGICAL-ROLE | GROUP-X | BIOCHEMISTRY & MOLECULAR BIOLOGY | Inflammation | FACTOR-KAPPA-B | MITOCHONDRIAL-DNA | HUMAN T-CELLS | CELL BIOLOGY | Secreted phospholipase A | Infectious diseases | BIOPHYSICS | SMOOTH-MUSCLE-CELLS | STAPHYLOCOCCUS-AUREUS | KRUPPEL-LIKE FACTOR-2 | Platelets | CELL-MEMBRANE HYDROLYSIS | Microbiome
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 06/2019, Volume 1864, Issue 6, pp. 789 - 802
Among all members of the secreted phospholipase A (sPLA ) family, group IIA sPLA (sPLA -IIA) is possibly the most studied enzyme. Since its discovery, many... 
Inflammation | Infectious diseases | Platelets | Secreted phospholipase A2 | Microbiome
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 10/2000, Volume 1488, Issue 1-2, pp. 1 - 19
Journal Article
Infection and Immunity, ISSN 0019-9567, 05/2018, Volume 86, Issue 8
ABSTRACT Human innate immunity employs cellular and humoral mechanisms to facilitate rapid killing of invading bacteria. The direct killing of bacteria by... 
Journal Article
Atherosclerosis, ISSN 0021-9150, 10/2010, Volume 212, Issue 2, pp. 357 - 366
Journal Article
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 03/2018, Volume 1863, Issue 3, pp. 247 - 265
Cancer cells driven by the Ras oncogene scavenge unsaturated fatty acids (FAs) from their environment to counter nutrient stress. The human group X secreted... 
Unsaturated fatty acids | Adipose triglyceride lipase | Breast cancer | Lipotoxicity | Lipid droplets | Secreted phospholipase A2 | Secreted phospholipase A
Journal Article
Infection and Immunity, ISSN 0019-9567, 08/2018, Volume 86, Issue 8
Human innate immunity employs cellular and humoral mechanisms to facilitate rapid killing of invading bacteria. The direct killing of bacteria by human serum... 
Enterococcus faecium | Pathogens | Innate immune system | Commensals | Group IIA secreted phospholipase A2
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 03/2018, Volume 1863, Issue 3, pp. 247 - 265
Cancer cells driven by the Ras oncogene scavenge unsaturated fatty acids (FAs) from their environment to counter nutrient stress. The human group X secreted... 
GROUP-V | PPAR-ALPHA | GROUP-X | OXIDATIVE STRESS | GROUP-IIA | Lipid droplets | BIOCHEMISTRY & MOLECULAR BIOLOGY | Breast cancer | ENDOPLASMIC-RETICULUM STRESS | CHOLESTERYL ESTER ACCUMULATION | CELL BIOLOGY | Unsaturated fatty acids | Adipose triglyceride lipase | Secreted phospholipase A | BIOPHYSICS | LIPOLYSIS | GROWTH | Lipotoxicity
Journal Article