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Annals of Oncology, ISSN 0923-7534, 03/2014, Volume 25, Issue 3, pp. 552 - 563
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 11/2014, Volume 111, Issue 45, pp. E4869 - E4877
The human FGF receptors (FGFRs) play critical roles in various human cancers, and several FGFR inhibitors are currently under clinical investigation.... 
Structure-based drug design | Drug discovery | Cancer drug resistance | Kinase inhibitor | structure-based drug design | WILD-TYPE | MULTIDISCIPLINARY SCIENCES | BCR-ABL | GROWTH-FACTOR RECEPTORS | DRUG-RESISTANCE | kinase inhibitor | LUNG-CANCER | GENE FUSIONS | cancer drug resistance | SELECTIVE INHIBITOR | drug discovery | THERAPEUTIC TARGET | FACTOR RECEPTOR 4 | REGULATES PROLIFERATION | Receptor, Fibroblast Growth Factor, Type 4 - chemistry | Receptor, Fibroblast Growth Factor, Type 4 - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - chemistry | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Humans | ErbB Receptors - genetics | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Crystallography, X-Ray | Structure-Activity Relationship | Mutation, Missense | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Protein Kinase Inhibitors - chemistry | Neoplasms - genetics | Receptor, Fibroblast Growth Factor, Type 2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Binding Sites | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Neoplasms - enzymology | Antineoplastic Agents - chemistry | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | ErbB Receptors - chemistry | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - chemistry | Neoplasms - pathology | Receptor, Fibroblast Growth Factor, Type 4 - antagonists & inhibitors | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Amino Acid Substitution | Drug Resistance, Neoplasm - drug effects | Biological Sciences | PNAS Plus
Journal Article
Macromolecules, ISSN 0024-9297, 12/2012, Volume 45, Issue 24, pp. 9768 - 9778
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2012, Volume 209, Issue 11, pp. 2001 - 2016
.... We provide evidence that Neuropilin 1 (Nrp-1), highly expressed by Foxp3(+) T reg cells, regulates the immunological anti-tumor control by guiding T reg cells into the tumor in response to tumor-derived vascular endothelial growth factor (VEGF... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | ANTI-VEGF | DENDRITIC CELLS | ANGIOGENESIS | AUTOIMMUNITY | RECEPTOR | SELECTIVE DEPLETION | MALIGNANT-MELANOMA | IMMUNOLOGY | EXPRESSION | TUMOR-IMMUNITY | Forkhead Transcription Factors - immunology | Immunohistochemistry | Neuropilin-1 - genetics | T-Lymphocytes, Regulatory - metabolism | Vascular Endothelial Growth Factor A - deficiency | Tumor Escape - genetics | Humans | Gene Expression Regulation, Neoplastic | Melanoma, Experimental - metabolism | Vascular Endothelial Growth Factor A - genetics | Cell Movement - genetics | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Melanoma, Experimental - immunology | Forkhead Transcription Factors - metabolism | CD8-Positive T-Lymphocytes - metabolism | Tumor Burden - genetics | Neuropilin-1 - immunology | Tumor Escape - immunology | Skin Neoplasms - immunology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | Vascular Endothelial Growth Factor A - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Skin Neoplasms - metabolism | Animals | Melanoma, Experimental - genetics | Skin Neoplasms - genetics | Cell Line, Tumor | Mice | CD8-Positive T-Lymphocytes - immunology | Neuropilin-1 - deficiency | Tumor Burden - immunology
Journal Article
Journal of Crystal Growth, ISSN 0022-0248, 06/2015, Volume 419, pp. 88 - 93
With the objective of introducing further GaN semipolar orientations adequate for the fabrication of optoelectronic devices on silicon, we report on the selective area growth of semipolar (202̄1... 
A1. Selective area growth | Semipolar | B1. Silicon | GaN | B1. Silicon GaN Semipolar | Thermodynamics | Anisotropy | Growth | Optical properties | Epitaxy | Silicon | Liquors | Electron microscopy | Immunoglobulin A | Stacking faults | Gallium nitrides | Silicon substrates | Optoelectronic devices | Etching | Dislocations
Journal Article
Fatigue & Fracture of Engineering Materials & Structures, ISSN 8756-758X, 10/2015, Volume 38, Issue 10, pp. 1228 - 1236
Experimental investigation was conducted to evaluate the fracture toughness and fatigue crack growth characteristics in selective laser‐melted titanium 6Al‐4... 
selective laser melting | additive manufacturing | fracture toughness | selective laser sintering | fatigue crack growth | titanium
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2012, Volume 337, Issue 6099, pp. 1231 - 1235
.... Here, we report that a small subset of GBMs (3.1%; 3 of 97 tumors examined) harbors oncogenic chromosomal translocations that fuse in-frame the tyrosine kinase coding domains of fibroblast growth factor receptor (FGFR) genes (FGFR1 or FGFR3... 
Exons | Neurons | Genes | REPORTS | Stem cells | Aneuploidy | Chromosomes | Cells | Tumors | Daughter cells | Cancer | ANEUPLOIDY | SELECTIVE INHIBITOR | POTENT | MULTIDISCIPLINARY SCIENCES | CANCER | RECEPTOR TYROSINE KINASE | DISCOVERY | CHROMOSOMAL INSTABILITY | FAMILY | Microtubule-Associated Proteins - chemistry | Neoplasm Transplantation | Translocation, Genetic | Oncogene Proteins, Fusion - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - chemistry | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Mitosis | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Receptor, Fibroblast Growth Factor, Type 3 - antagonists & inhibitors | Fetal Proteins - metabolism | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Receptor, Fibroblast Growth Factor, Type 3 - metabolism | Brain Neoplasms - metabolism | Oncogene Proteins, Fusion - chemistry | Spindle Apparatus - metabolism | Glioblastoma - genetics | Oncogene Fusion | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Nuclear Proteins - genetics | Chromosomal Instability | Pyrazoles - pharmacology | Protein Structure, Tertiary | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Enzyme Inhibitors - pharmacology | Brain Neoplasms - genetics | Nuclear Proteins - metabolism | Pyrimidines - pharmacology | Nuclear Proteins - chemistry | Piperazines - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Cell Transformation, Neoplastic | Oncogene Proteins, Fusion - genetics | Fetal Proteins - genetics | Mice | Receptor, Fibroblast Growth Factor, Type 1 - chemistry | Fetal Proteins - chemistry | Physiological aspects | Development and progression | Fibroblast growth factors | Genetic aspects | Research | Health aspects | Glioblastoma multiforme | Proteins | Kinases | Brain cancer | Genomics | Pharmaceutical sciences
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 12/2009, Volume 131, Issue 49, pp. 17871 - 17878
.... Furthermore, growth of semiconductor shells with systematic shape evolution using the same metal particle cores can also present a significant challenge... 
SEED-MEDIATED SYNTHESIS | RATIO GOLD NANORODS | METAL NANOCRYSTALS | SELECTIVE GROWTH | FACILE SYNTHESIS | ONE-POT SYNTHESIS | EPITAXIAL-GROWTH | GENERAL-APPROACH | DIFFERENT SIZE RANGES | HOLLOW NANOCUBES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e80954
Journal Article