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Current Topics in Medicinal Chemistry, ISSN 1568-0266, 04/2017, Volume 17, Issue 11, pp. 1237 - 1248
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2015, Volume 348, Issue 6241, pp. 1376 - 1381
The development of effective pharmacological inhibitors of multidomain scaffold proteins, notably transcription factors, is a particularly challenging problem.... 
SELECTIVE-INHIBITION | UBIQUITINATION | CELLS | COMPLEX | ACTIVATION | MULTIDISCIPLINARY SCIENCES | THALIDOMIDE | LEUKEMIA | CANCER | BET BROMODOMAINS | MOLECULES | Transcription factors | Identification and classification | Health aspects | Protein-protein interactions | Proteins | Molecular biology | Leukemia | Rodents | Degradation | Enzymes | Progressions | Phthalimides | Strategy | Leukemias | Cancer
Journal Article
The Journal of cell biology, ISSN 0021-9525, 2012, Volume 197, Issue 7, pp. 857 - 867
Journal Article
Blood, ISSN 1528-0020, 2018, Volume 131, Issue 3, pp. 328 - 341
Transgenic expression of ASXL1aa1-587 truncating protein in the hematopoietic system leads to diverse myeloid malignancies in mice. ASXL1aa1-587 gains an... 
SELECTIVE-INHIBITION | GENE ASXL1 | TRANSFORMATION | CHROMATIN | ADDITIONAL-SEX-COMBS | MUTATIONS | HEMATOLOGY | TRANSCRIPTIONAL REGULATION | MYELODYSPLASTIC SYNDROMES | CHRONIC MYELOMONOCYTIC LEUKEMIA | BRD4 | Myeloid Neoplasia
Journal Article