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index medicus (509) 509
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humans (292) 292
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amino acid sequence (165) 165
major histocompatibility complex (146) 146
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t-lymphocytes - immunology (126) 126
abridged index medicus (117) 117
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biochemistry & molecular biology (94) 94
autoimmunity (91) 91
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peptide fragments - immunology (73) 73
receptors, antigen, t-cell - immunology (73) 73
ligands (67) 67
positive selection (67) 67
protein binding (66) 66
class-i molecules (58) 58
female (58) 58
receptors, antigen, t-cell - metabolism (58) 58
mhc (56) 56
t-lymphocytes, cytotoxic - immunology (56) 56
cd4-positive t-lymphocytes - immunology (55) 55
negative selection (55) 55
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complex (53) 53
multidisciplinary sciences (53) 53
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in-vivo (50) 50
lymphocytes (50) 50
identification (49) 49
models, molecular (49) 49
t-cell-receptor (49) 49
proteins (47) 47
transgenic mice (47) 47
histocompatibility antigens class ii - immunology (46) 46
alleles (45) 45
crystal-structure (45) 45
expression (44) 44
peptides - metabolism (44) 44
self-assembly (44) 44
t-cells (44) 44
protein conformation (43) 43
myelin basic-protein (42) 42
peptide fragments - metabolism (42) 42
thymic selection (42) 42
thymus gland - immunology (42) 42
epitopes (41) 41
medicine, research & experimental (41) 41
chemical and pharmacologic phenomena (40) 40
lymphocyte activation (40) 40
thymus gland - cytology (40) 40
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cells, cultured (39) 39
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histocompatibility antigens class ii - metabolism (39) 39
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histocompatibility antigens class i - immunology (37) 37
lymphocyte activation - immunology (37) 37
structural basis (37) 37
autoantigens - immunology (36) 36
mhc molecules (36) 36
mice, inbred balb c (36) 36
mice, knockout (36) 36
viral peptides (36) 36
cd8-positive t-lymphocytes - immunology (35) 35
peptide fragments - chemistry (35) 35
t cell receptors (35) 35
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thymus (35) 35
protein binding - immunology (34) 34
cell biology (33) 33
tcr (33) 33
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t-lymphocytes - metabolism (32) 32
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JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 06/2011, Volume 208, Issue 6, pp. 1279 - 1289
The ability of antigen receptors to engage self-ligands with varying affinity is crucial for lymphocyte development. To further explore this concept, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | NKT CELLS | POSITIVE SELECTION | RECOGNITION | THYMIC SELECTION | NEGATIVE SELECTION | CLONAL DELETION | IMMUNOLOGY | SELF-PEPTIDES | IDENTIFICATION | STAT5 ACTIVATION | ANTIGEN
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8
Major histocompatibility complex (MHC) class I molecules (proteins) bind peptides of eight to ten amino acids to present them at the cell surface to cytotoxic... 
FREE-ENERGY CALCULATIONS | TAPASIN DEPENDENCE | COMPLEX | T-CELL RESPONSES | BINDING GROOVE | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CONFORMATIONAL FLEXIBILITY | ANTIGEN PRESENTATION | SELF-PEPTIDES | PROTEINS
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 243 - 247
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2014, Volume 192, Issue 7, pp. 2984 - 2993
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2018, Volume 200, Issue 12, pp. 4134 - 4145
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2001, Volume 2, Issue 6, pp. 501 - 507
The class II major histocompatibility complex (MHC) glycoproteins HLA-DQ8 and HLA-DQ2 in humans and I-A(g7) in nonobese diabetic (NOD) mice are the major risk... 
MYELIN BASIC-PROTEIN | NOD MOUSE | GLUTAMIC-ACID DECARBOXYLASE | PEPTIDE-BINDING | CRYSTAL-STRUCTURE | HLA-DQ | MAJOR HISTOCOMPATIBILITY COMPLEX | T-CELL EPITOPE | IMMUNOLOGY | SELF-PEPTIDES | CELIAC-DISEASE
Journal Article
Journal Article
DIABETES, ISSN 0012-1797, 05/2019, Volume 68, Issue 5, pp. 879 - 886
Journal Article