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Molecular Cell, ISSN 1097-2765, 03/2018, Volume 69, Issue 6, pp. 1028 - 1038.e6
N -methyladenosine (m A) is an abundant modification in eukaryotic mRNA, regulating mRNA dynamics by influencing mRNA stability, splicing, export, and... 
nuclear localization | mESC self-renewal | Zc3h13
Journal Article
Nature, ISSN 0028-0836, 04/2009, Volume 458, Issue 7240, pp. 904 - 908
Maintenance of the blood system is dependent on dormant haematopoietic stem cells (HSCs) with long-term self-renewal capacity. After injury these cells are... 
NICHES | THERAPY | MULTIDISCIPLINARY SCIENCES | DISEASE | SELF-RENEWAL | MICE | INTERFERONS | EXPRESSION | CHRONIC MYELOID-LEUKEMIA
Journal Article
ISSN 1078-8956, 2017
Human liver cancer research currently lacks in vitro models that can faithfully recapitulate the pathophysiology of the original tumor. We recently described a... 
cancer models | self-renewal | disease model
Journal Article
Genes and Development, ISSN 0890-9369, 03/2009, Volume 23, Issue 5, pp. 561 - 574
Journal Article
BLOOD, ISSN 0006-4971, 05/2012, Volume 119, Issue 21, pp. 4819 - 4820
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2016, Volume 113, Issue 14, pp. E2047 - E2056
N-6-methyladenosine (m(6)A) modification of mRNA plays a role in regulating embryonic stem cell pluripotency. However, the physiological signals that determine... 
TUMOR HYPOXIA | MULTIDISCIPLINARY SCIENCES | hypoxia-inducible factors | self-renewal | CHEMOTHERAPY | pluripotency factors | DEMETHYLASE | INDUCIBLE FACTORS | N-6-METHYLADENOSINE | MAINTENANCE | FACTOR-1 | metastasis | tumorigenesis | EXPRESSION
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2019, Volume 25, Issue 4, pp. 1415 - 1429
Purpose: Niclosamide, an FDA-approved anthelmintic drug, has been characterized as a potent Wnt inhibitor that can suppress tumor growth and cancer stem-like... 
CELLS | ONCOLOGY | MARKER | TUMOR | DRUG NICLOSAMIDE | SELF-RENEWAL | TUMORIGENESIS
Journal Article
STEM CELLS, ISSN 1066-5099, 09/2008, Volume 26, Issue 9, pp. 2257 - 2265
Defined growth conditions are essential for many applications of human embryonic stem cells (hESC). Most defined media are presently used in combination with... 
Human embryonic stem cells | Extracellular matrix | Self‐renewal | Defined substrate | Integrins | Self-renewal
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2019, Volume 49, Issue 3, pp. 311 - 312
Dormant cancer cells often survive treatment and increase the risk for tumor relapse, associated with dismal prognosis. Two recent papers describe mechanisms... 
SELF-RENEWAL | DEVELOPMENTAL BIOLOGY | LEUKEMIA | CELL BIOLOGY | Leukemia | Hematopoietic stem cells
Journal Article
Science, ISSN 0036-8075, 10/2014, Volume 346, Issue 6205, pp. 54 - 54
Stem cells fuel tissue development, renewal, and regeneration, and these activities are controlled by the local stem cell microenvironment, the "niche." Wnt... 
WNT/BETA-CATENIN | POSTNATAL MAMMARY-GLAND | MULTIDISCIPLINARY SCIENCES | IN-VITRO EXPANSION | PLANARIAN REGENERATION | SELF-RENEWAL | SMALL-INTESTINE | TUMOR-SUPPRESSOR | STEM/PROGENITOR CELLS | KIDNEY DEVELOPMENT | LONG-TERM EXPANSION | Signal transduction | Tissue | Mammals | Stem cells | Proteins | Regeneration | Intestines | Integrals | Organs | Emission
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2013, Volume 126, Issue 18, pp. 4220 - 4229
Journal Article
NATURE, ISSN 0028-0836, 09/2006, Volume 443, Issue 7110, pp. 421 - 426
Stem-cell ageing is thought to contribute to altered tissue maintenance and repair. Older humans experience increased bone marrow failure and poorer... 
PROGENITOR CELLS | ENGRAFTMENT | P19(ARF) | MULTIDISCIPLINARY SCIENCES | IN-VIVO | INCREASES | SELF-RENEWAL | MICE | SENESCENCE | EXPRESSION | HEMATOPOIETIC STEM
Journal Article
Cell Stem Cell, ISSN 1934-5909, 12/2018, Volume 23, Issue 6, pp. 773 - 774
Identification of tumor-initiating populations could provide insights into tumor heterogeneity and responses to treatments, but this has proven difficult in... 
SELF-RENEWAL | GROWTH | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
NATURE, ISSN 0028-0836, 09/2006, Volume 443, Issue 7110, pp. 448 - 452
Mammalian ageing is associated with reduced regenerative capacity in tissues that contain stem cells(1,2). It has been proposed that this is at least partially... 
TUMOR SUPPRESSION | MULTIDISCIPLINARY SCIENCES | GROWTH | SELF-RENEWAL | PROLIFERATION | SENESCENCE | MICE | NEURAL STEM-CELL | SUBVENTRICULAR ZONE | TUMORIGENESIS | ADULT
Journal Article
Cell Stem Cell, ISSN 1934-5909, 10/2014, Volume 15, Issue 4, pp. 471 - 487
Embryonic stem cells (ESCs) of mice and humans have distinct molecular and biological characteristics, raising the question of whether an earlier, “naive”... 
EPIBLAST | DERIVATION | INACTIVATION | SOMATIC-CELLS | GROUND-STATE PLURIPOTENCY | EMBRYONIC STEM-CELLS | SELF-RENEWAL | INHIBITORS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2018, Volume 38, Issue 13, pp. 3157 - 3159
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2011, Volume 85, Issue 6, pp. 1114 - 1123
ABSTRACT Insight regarding mechanisms controlling gene expression in the spermatogonial stem cell (SSC) will improve our understanding of the processes... 
Brachyury | spermatogonial stem cells | self-renewal | ETV5 | Self-renewal | Spermatogonial stem cells | Etv5
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2018, Volume 69, Issue 6, pp. 1028 - 1038.e6
-methyladenosine (m A) is an abundant modification in eukaryotic mRNA, regulating mRNA dynamics by influencing mRNA stability, splicing, export, and... 
nuclear localization | mESC self-renewal | m6A | Zc3h13 | Index Medicus
Journal Article
PLOS ONE, ISSN 1932-6203, 01/2011, Volume 6, Issue 1
Background: Cancer stem cells (CSCs) can proliferate and self-renew extensively due to their ability to express anti-apoptotic and drug resistant proteins,... 
BREAST-CANCER | METASTASIS | MARKER | PROSPECTIVE IDENTIFICATION | NONALCOHOLIC COMPOUNDS | BIOLOGY | SELF-RENEWAL | NANOG | DRUG-RESISTANCE | CARCINOMA | MOLECULAR-MECHANISMS
Journal Article
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