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Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 41, pp. 70142 - 70155
The small ubiquitin-related modifier (SUMO) system is essential for smooth progression of cell cycle at the G2/M phase. Many centromeric proteins are... 
PIAS4 | Polyploidy | SUMOylation | SENP2 | ORC2
Journal Article
Cell Reports, ISSN 2211-1247, 08/2019, Volume 28, Issue 8, pp. 2004 - 2011.e4
Brown adipose tissue (BAT) is a thermogenic organ that maintains body temperature and energy homeostasis. Transcriptional regulation plays an important role in... 
Necdin | CREB | SUMOylation | brown adipogenesis | SENP2 | PATHWAY | PRDM16 | TRANSCRIPTIONAL CONTROL | FAT | ADIPOGENESIS | SUMOYLATION | ADIPOSE-TISSUE | CELL BIOLOGY
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 07/2019, Volume 854, pp. 179 - 186
Doxorubicin is a chemotherapeutic agent commonly used to treat breast cancer. However, breast cancer often develops drug resistance, leading to disease... 
NF-κB | Breast cancer cell | NEMO SUMOylation | SENP2 | Doxorubicin resistance | APOPTOSIS | MECHANISM | ALPHA | DRUG-RESISTANCE | SUMOYLATION | REVERSAL | INACTIVATION | NE-kappa B | INHIBITION | PHARMACOLOGY & PHARMACY | SUMO-1 | EXPRESSION
Journal Article
Toxicology Letters, ISSN 0378-4274, 06/2018, Volume 289, pp. 86 - 98
SUMOylation and deSUMOylation, a dynamic process, is proved to be involved in various fibrotic diseases. Here, we found SENP2, one of deSUMOylation protease... 
β-catenin | HSC | Liver fibrosis | SENP2 | REGRESSION | SUMO | ss-catenin | BETA-CATENIN | CANCER | SUMOYLATION | THERAPEUTIC TARGET | TOXICOLOGY | HEPATOCELLULAR-CARCINOMA CELL | AXIN-BINDING PROTEIN | DESUMOYLATION | EXPRESSION | Index Medicus
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 09/2019, Volume 33, Issue 9, pp. 10218 - 10230
SUMOylation is a highly conserved and dynamic post-translational mechanism primarily affecting nuclear programs for adapting organisms to stressful challenges.... 
beta-catenin | mouse models | PIAS3 | REGULATORY SUBUNIT | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PKA | KINASE | SUMO-1 MODIFICATION | SENP1 | BETA | CELL BIOLOGY | 2 | ADRENOCORTICAL DEVELOPMENT | endocrine diseases | PATHWAY | IN-VIVO | BIOLOGY | GENE-EXPRESSION | PROTEASE SENP2 | Index Medicus
Journal Article
Journal of Molecular Cell Biology, ISSN 1674-2788, 06/2018, Volume 10, Issue 3, pp. 258 - 266
Abstract One major function of adipocytes is to store excess energy in the form of triglycerides. Insufficient adipose lipid storage is associated with many... 
Lipid storage | Pparg and Cebpa | H3K9me3 | Setdb1 | Senp2 | PROTEASE 2 | LIPODYSTROPHIES | TISSUE | lipid storage | CELL BIOLOGY | METABOLISM | INSULIN-RESISTANCE | ACTIVATED-RECEPTOR-GAMMA | FAT | PPAR-GAMMA | KNOCKOUT | EXPRESSION
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2012, Volume 13, Issue 8, pp. 3583 - 3587
SUMOylation has emerged as an important post-translational modification that modulates the localization, stability and activity of a broad spectrum of... 
β-Catenin | Hepg2 cells | hepatocellular carcinoma | Senp2 | beta-catenin | SUMO | ONCOLOGY | PROTEASE 2 | HepG2 cells | MICE | SENP2 | DESUMOYLATION | SUMOYLATION | CYCLE
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9786 - 12
Journal Article
Journal Article