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Menopause, ISSN 1072-3714, 11/2009, Volume 16, Issue 6, pp. 1193 - 1196
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 02/2016, Volume 24, Issue 4, pp. 759 - 767
Raloxifene, a selective estrogen receptor modulator (SERM), reduces fracture risk at least in part by improving the mechanical properties of bone in a cell-... 
Raloxifene | Bone powder | SERM | Collagen
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 03/2015, Volume 15, Issue 14, pp. 1372 - 1384
Estrogen receptors, comprised of ER alpha and ER beta isoforms in mammals, act as ligand-modulated transcription factors and orchestrate a plethora of cellular... 
Endoestrogens | Estrogen receptors | Phytoestrogens | SERMs | Xenoestrogens | Metalloestrogens | ENDOCRINE-DISRUPTING CHEMICALS | DNA-BINDING DOMAIN | TRANSCRIPTIONAL ACTIVATION | CHEMISTRY, MEDICINAL | ACTIVATED PROTEIN-KINASE | ER-BETA | ENVIRONMENTAL ESTROGENS | NUCLEAR HORMONE-RECEPTORS | BREAST-CANCER CELLS | MALE REPRODUCTIVE FUNCTION | BETA-SELECTIVE SERMS
Journal Article
Journal Article
Bone, ISSN 8756-3282, 10/2019, Volume 127, pp. 199 - 206
Current interventions to reduce skeletal fragility are insufficient at enhancing both the quantity and quality of bone when attempting to improve overall... 
Bone quality | Bisphosphonate | SERM | Osteogenesis Imperfecta | Fracture toughness | Index Medicus
Journal Article
International Journal of Oncology, ISSN 1019-6439, 05/2010, Volume 36, Issue 5, pp. 1067 - 1080
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY A, ISSN 1089-5639, 07/2019, Volume 123, Issue 28, pp. 6016 - 6021
The gas-phase acidity of ferrocene (Delta H degrees(acid)(1) = 391.5 +/- 1.3 kcal mol(-1)) and electron affinity of the ferrocenyl radical (EA(1r) = 1.74 +/-... 
DENSITY FUNCTIONALS | SERMS | ESTROGEN-RECEPTOR MODULATORS | THERMOCHEMISTRY | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | ENERGETICS | CHEMISTRY, PHYSICAL | POTENTIALS | PROTON-TRANSFER | DERIVATIVES | IONIZATION
Journal Article
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 2013, Volume 13, Issue 3, pp. 464 - 475
Journal Article
European Journal of Obstetrics and Gynecology, ISSN 0301-2115, 1999, Volume 85, Issue 1, pp. 47 - 51
Phytoestrogens are diphenolic compounds that are present in several plants eaten by human beings. Soybeans and flaxseed are particularly abundant source of... 
Hot flushes | Osteoporosis | Phytoestrogens | Lipoproteins | SERMs | Menopause
Journal Article
The EMBO Journal, ISSN 0261-4189, 2009, Volume 28, Issue 10, pp. 1418 - 1428
We used ChIP‐Seq to map ERα‐binding sites and to profile changes in RNA polymerase II (RNAPII) occupancy in MCF‐7 cells in response to estradiol (E2),... 
SERMs | estrogen receptor α | RNA polymerase II | ChIP‐Seq | Estrogen receptor a | ChIP-Seq | TAMOXIFEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | estrogen receptor alpha | PROLIFERATION | CELL BIOLOGY | BREAST-CANCER CELLS | HUMAN GENOME | PROMOTERS | ESTROGEN-RECEPTOR-ALPHA | MCF-7 CELLS | BINDING-SITES | TRANSCRIPTIONAL REGULATION | EXPRESSION
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 41, pp. 9751 - 9759
Novel C-2-symmetric N,N'-bis-[(pyrrolidin-2-yl)methyl-squaramide] TFA salts bearing (R,R)- or (S,S)-1,2di(pyridin-2-yl)ethane spacer groups were synthesized... 
BREAST-CANCER | KETONES | BETA-NITROSTYRENES | (-)-PANCRACINE | ENANTIOSELECTIVE CONJUGATE ADDITION | NITROOLEFINS | CHEMISTRY, ORGANIC | KETOESTERS | RECEPTOR MODULATORS SERMS | NITROALKENES | ALKALOIDS
Journal Article
Frontiers in Endocrinology, ISSN 1664-2392, 2012, Volume 3, pp. 19 - 19
The roles of estrogens have been best studied in the breast, breast cancers, and in the female reproductive tract. However, estrogens have important functions... 
Aging | Tissue specificity | SERM | Estrogen | estrogen | tissue specificity
Journal Article
Anti-cancer agents in medicinal chemistry, ISSN 1871-5206, 2018, Volume 18, Issue 7, pp. 1016 - 1024
Purpose: Some aromatase inhibitors are FDA-approved agents as first-line therapy in the treatment of endocrine-responsive breast cancer. In this study, we... 
imidazole derivatives | breast cancer | estrogen | triazole derivatives | AIS | Aromatase inhibitors | CHEMISTRY, MEDICINAL | SPECIFICITY | DISCOVERY | FADROZOLE | SERMS | ONCOLOGY | BIOSYNTHESIS | STEROID SULFATASE
Journal Article
Post Reproductive Health, ISSN 2053-3691, 12/2018, Volume 24, Issue 4, pp. 167 - 170
The British Menopause Society Council aims to aid health professionals to inform and advise women about post reproductive health. Osteoporosis affects one in... 
calcium and vitamin D | HRT | SERMs | PTH | Bisphosphonates | denosumab
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2015, Volume 16, Issue 6, pp. 2161 - 2166
Journal Article
Neuroscience, ISSN 0306-4522, 2006, Volume 145, Issue 2, pp. 592 - 604
Abstract Phytoestrogens prevent neuronal damage, however, mechanism of their neuroprotective action has not been fully elucidated. This study aimed to evaluate... 
Neurology | phytoestrogen | apoptosis | SERM | excitotoxicity | brain tissues
Journal Article
Journal of Endocrinological Investigation, ISSN 0391-4097, 7/2016, Volume 39, Issue 7, pp. 807 - 834
Journal Article