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serratia marcescens (129) 129
escherichia-coli (100) 100
serratia marcescens - enzymology (97) 97
microbiology (96) 96
index medicus (89) 89
biochemistry & molecular biology (81) 81
serratia-marcescens (71) 71
molecular sequence data (65) 65
serratia marcescens - genetics (64) 64
animals (59) 59
bacteria (58) 58
amino acid sequence (55) 55
biotechnology & applied microbiology (50) 50
nuclease (47) 47
dna (45) 45
base sequence (43) 43
humans (42) 42
gene (38) 38
purification (38) 38
bacterial proteins - genetics (37) 37
proteins (36) 36
bacterial proteins - metabolism (35) 35
serratia marcescens - metabolism (35) 35
research (34) 34
analysis (31) 31
escherichia coli - genetics (31) 31
endonucleases - metabolism (30) 30
expression (29) 29
mechanism (29) 29
mutation (28) 28
escherichia coli (27) 27
gram-negative bacteria (27) 27
identification (27) 27
enzymes (26) 26
protein (26) 26
research article (26) 26
endonuclease (25) 25
prodigiosin (25) 25
endodeoxyribonucleases - metabolism (23) 23
gene expression (23) 23
pseudomonas-aeruginosa (23) 23
virulence (23) 23
kinetics (22) 22
secretion (22) 22
biotechnology (21) 21
extracellular nuclease (21) 21
life sciences (21) 21
models, molecular (21) 21
serratia marcescens - growth & development (21) 21
binding sites (20) 20
endoribonucleases - metabolism (20) 20
genes, bacterial (20) 20
dna - metabolism (19) 19
mutagenesis (19) 19
serratia marcescens - drug effects (19) 19
serratia marcescens - physiology (19) 19
binding (18) 18
cloning (18) 18
cloning, molecular (18) 18
endodeoxyribonucleases - chemistry (18) 18
genes (18) 18
pathogens (18) 18
physiological aspects (18) 18
cell biology (17) 17
deoxyribonucleases - metabolism (17) 17
endodeoxyribonucleases - genetics (17) 17
gene expression regulation, bacterial (17) 17
genetic aspects (17) 17
health aspects (17) 17
plasmids (17) 17
genetics & heredity (16) 16
hydrogen-ion concentration (16) 16
serratia-marcescens endonuclease (16) 16
apoptosis (15) 15
deoxyribonucleic acid--dna (15) 15
e coli (15) 15
endonucleases - chemistry (15) 15
nucleases (15) 15
proteases (15) 15
protein binding (15) 15
article (14) 14
bacterial proteins - chemistry (14) 14
crystal-structure (14) 14
dna, bacterial - genetics (14) 14
electrophoresis, polyacrylamide gel (14) 14
endoribonucleases - genetics (14) 14
infections (14) 14
multidisciplinary sciences (14) 14
quorum sensing (14) 14
sequence alignment (14) 14
serratia-marcescens nuclease (14) 14
substrate specificity (14) 14
temperature (14) 14
virulence factors (14) 14
biophysics (13) 13
chemistry (13) 13
endoribonucleases - chemistry (13) 13
escherichia coli - enzymology (13) 13
hydrolysis (13) 13
medicine (13) 13
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PLoS Computational Biology, ISSN 1553-734X, 07/2017, Volume 13, Issue 7, p. e1005652
Bacteria exploit an arsenal of antimicrobial peptides and proteins to compete with each other. Three main competition systems have been described: type six... 
IMMUNITY PROTEIN | SEQUENCE-ANALYSIS | OUTER-MEMBRANE | PLASMIDS | ESCHERICHIA-COLI STRAINS | GENE-CLUSTER | PSEUDOMONAS-AERUGINOSA | PORIN OMPF | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | SERRATIA-MARCESCENS | ENDONUCLEASE COLICINS | Gammaproteobacteria - enzymology | Markov Chains | Bacterial Proteins - genetics | Genome, Bacterial - physiology | Anti-Infective Agents | Deoxyribonucleases - metabolism | Deoxyribonucleases - genetics | Genome, Bacterial - genetics | Bacteriocins - genetics | Pseudomonas aeruginosa - genetics | Pseudomonas aeruginosa - enzymology | Computer Simulation | Bacterial Proteins - metabolism | Gammaproteobacteria - genetics | Usage | Genetic aspects | Models | Bacteriocins | Hidden Markov models | Biological diversity | Competition | Peptides | Funding | Zoology | Virulence | Genes | Markov chains | Genomes | Infections | Biochemistry | Drug resistance | Data bases | Proteins | Conserved sequence | E coli | Virulence factors | Network analysis | Antimicrobial peptides | Bacteria | Pseudomonas aeruginosa | Gram-negative bacteria | Nuclease | Protein transport | Bioinformatics | Deoxyribonucleic acid--DNA | Translocation | Killing | Plants (botany) | Pathogens | Bacterial infections | tRNA | Secretion | rRNA | Cloning | Antimicrobial agents | Roles | Nucleic acids | Colicins | Ecological niches | Plasmids | Toxins | Periplasm | Cytoplasm | Niches | Deoxyribonucleic acid | DNA
Journal Article
Biotechnology Letters, ISSN 0141-5492, 12/2017, Volume 39, Issue 12, pp. 1865 - 1873
To reduce unwanted Fab’ leakage from an autonucleolytic Escherichia coli strain, which co-expresses OmpA-signalled Staphylococcal nuclease and Fab’ fragment in... 
Life Sciences | Biochemistry, general | Leakage | Biotechnology | Microbiology | Autonucleolytic | Bioprocess | Applied Microbiology | Periplasm | Nuclease | Fab’ fragment | Fab' fragment | STAPHYLOCOCCAL-NUCLEASE | MEMBRANE | ANTIBODY FRAGMENTS | TRP | SERRATIA-MARCESCENS NUCLEASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PURIFICATION | FERMENTATION | SECRETION | PROMOTER | EXPRESSION | Metabolic Engineering | Endoribonucleases - genetics | Escherichia coli - enzymology | Endoribonucleases - metabolism | Immunoglobulin Fab Fragments - genetics | Cell Survival | Protein Disulfide-Isomerases - metabolism | Escherichia coli Proteins - metabolism | Endodeoxyribonucleases - genetics | Protein Disulfide-Isomerases - genetics | Bacterial Outer Membrane Proteins - metabolism | Immunoglobulin Fab Fragments - metabolism | Protein Sorting Signals - genetics | Escherichia coli - genetics | Bioreactors - microbiology | Endodeoxyribonucleases - metabolism | Escherichia coli - metabolism | Escherichia coli Proteins - genetics | Recombinant Fusion Proteins - genetics | Bacterial Outer Membrane Proteins - genetics | Genetic aspects | Cellular signal transduction | Translocation (Genetics) | Health aspects | Escherichia coli | Translocation | Deoxyribonuclease | Media (culture) | Peptides | Cultivation | Toxicity | Agar | Complex media | Cell density | Fragmentation | Signal transduction | E coli | Growth media | Bioreactors | Serratia marcescens | Index Medicus | Original Research Paper
Journal Article
Journal Article
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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2007, Volume 282, Issue 8, pp. 5682 - 5690
Journal Article
Microbiology, ISSN 0026-2617, 1/2016, Volume 85, Issue 1, pp. 42 - 46
Comparative characterization of the pigmented and nonpigmented Serratia marcescens strains and their extracellular nuclease mutants was carried out. Biomass... 
Life Sciences | protease | Medical Microbiology | Microbiology | nuclease | mutants | Serratia marcescens | motility | prodigiosin | oxidative stress | BIOSYNTHESIS | MICROBIOLOGY | PRODIGIOSIN PRODUCTION | Genetic research | Proteases | Genetic aspects
Journal Article
BioNanoScience, ISSN 2191-1630, 12/2016, Volume 6, Issue 4, pp. 335 - 337
Serratia marcescens are well-known Gram-negative bacteria capable of excreting extracellular hydrolases, such as the nuclease—an enzyme that catalyzes... 
Engineering | Chromatographic purification | Serratia marcescens nuclease | Gel electrophoresis | Homogeneous enzyme | Circuits and Systems | Biological and Medical Physics, Biophysics | Mass spectrometry | Nanotechnology | Biomaterials
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 02/2018, Volume 9
One of the approaches to effective airway cleansing is the degradation of DNA into smaller fragments. For this purpose Pulmozyme (R) is used with high efficacy... 
Pulmozyme | Serratia marcescens nuclease | Hydrolysis of DNA | Sputum | Sma nuc | hydrolysis of DNA | ENZYME | MECHANISM | PURIFICATION | PHARMACOLOGY & PHARMACY | sputum | EXTRACELLULAR NUCLEASE | PROTEINS | EXPRESSION | Nucleases | Molecular targeted therapy | Innovations | Genetic aspects | Gram-negative bacteria | Properties | Health aspects
Journal Article
ChemBioChem, ISSN 1439-4227, 03/2012, Volume 13, Issue 5, pp. 713 - 721
Journal Article