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Journal of Neurochemistry, ISSN 0022-3042, 2010, Volume 114, Issue 6, pp. 1687 - 1700
Peripheral inflammation could play a role in the origin and development of certain neurodegenerative disorders. To ascertain this possibility, a model of... 
brain inflammation | ulcerative colitis | macrophage depletion | dopaminergic neurodegeneration | Parkinson’s disease | Parkinson's disease | C-REACTIVE PROTEIN | SINGLE INTRANIGRAL INJECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDIOPATHIC PARKINSONISM | GASTROINTESTINAL-TRACT | PROINFLAMMATORY CYTOKINES | BLOOD-BRAIN-BARRIER | NEUROSCIENCES | INFLAMMATORY-BOWEL-DISEASE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | RAT-BRAIN | HELICOBACTER-PYLORI | Dextran Sulfate | Microglia - metabolism | Neurons - pathology | Rats, Wistar | Substantia Nigra - pathology | Astrocytes - pathology | Male | Substantia Nigra - metabolism | C-Reactive Protein - metabolism | Dopamine - physiology | Serum | Parkinson Disease - metabolism | Neurons - drug effects | Colitis, Ulcerative - complications | Parkinson Disease - pathology | Cytokines - metabolism | Macrophages - pathology | Colitis, Ulcerative - metabolism | Risk Factors | Rats | Colitis, Ulcerative - pathology | Blood-Brain Barrier - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Substantia Nigra - drug effects | Animals | Lipopolysaccharides - pharmacology | Astrocytes - metabolism | Nitric Oxide Synthase Type II - metabolism | Parkinson Disease - etiology | Dextran | Neurons | Nitric oxide | Inflammation | Permeability | Macrophages | Mitogens | Risk factors | Tumors | Ulcerative colitis | Neurochemistry | Inflammatory bowel disease | Rodents | Inflammatory diseases | Parkinsons disease | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e54600 - e54600
Background and Aim: Assessment of serum concentration of lipopolysaccharide (LPS)-binding protein (LBP) has been suggested as a useful biomarker to indicate... 
INCREASED INTESTINAL PERMEABILITY | THE-159C/T POLYMORPHISM | PLASMA-LEVELS | HIGH-DENSITY | MULTIDISCIPLINARY SCIENCES | GAMMA-GLUTAMYL-TRANSFERASE | PROMOTER REGION | ALCOHOL-CONSUMPTION | POTENTIAL ROLE | BACTERIAL-ENDOTOXIN | INCREASING PROTEIN | Age Factors | Obesity - immunology | Humans | Middle Aged | Male | Acute-Phase Proteins - genetics | Obesity - blood | Obesity - genetics | Inflammation - blood | Metabolic Syndrome - blood | Adult | Female | Metabolic Syndrome - immunology | Carrier Proteins - blood | Genetic Association Studies | Membrane Glycoproteins - blood | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Immunity, Innate | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Metabolic Syndrome - genetics | Adolescent | Inflammation - genetics | Lipopolysaccharide Receptors - genetics | Polymorphism, Single Nucleotide | Obesity | Blood cholesterol | Liver | Genetic aspects | Research | Mitogens | Genetic polymorphisms | Protein binding | Immunoassay | Demography | Low concentrations | Genes | Body weight | Source studies | Alcohol | Cardiovascular disease | Males | Metabolic syndrome | CD14 antigen | Lipopolysaccharides | Interleukin 6 | Proteins | Demographics | Microorganisms | Rodents | Toll-like receptors | Measurement methods | Population | Bioindicators | Lipoproteins (high density) | Interleukin 8 | Age | Consumption | Lipopolysaccharide-binding protein | Immune response | Cytokines | Internal medicine | Abnormalities | Glycoproteins | Inflammation | TLR4 protein | Cholesterol | Immune systems | Serum levels | Lipoproteins | Biomarkers | Sepsis | Adults | Lifestyles | Metabolic disorders | Smoking | Index Medicus
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 09/2017, Volume 66, Issue 3, pp. 953 - 968
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e106331 - e106331
Inflammation is a hallmark of several disease states ranging from neurodegeneration to sepsis but is also implicated in physiological processes like ageing.... 
COGNITIVE DECLINE | MICROGLIA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOBILITY GROUP BOX-1 | INNATE IMMUNE-SYSTEM | SICKNESS BEHAVIOR | DYSFUNCTION | BLOOD-BRAIN-BARRIER | NF-KAPPA-B | ASTROCYTES | Inflammation - chemically induced | Inflammation - pathology | Rats, Wistar | Lipopolysaccharides - administration & dosage | Astrocytes - pathology | Rats | Male | Hippocampus - pathology | Interleukin-1beta - genetics | Transcription Factor RelA - genetics | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Inflammation - metabolism | Animals | Aging - genetics | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Interleukin-1beta - metabolism | Aging - metabolism | Brain | Inflammation | RNA | Tumor necrosis factor | Mitogens | Neurosciences | Senescence | Disease | Laboratories | Central nervous system | Activation | Lipopolysaccharides | Proteins | Neurodegeneration | Rodents | Aging | Tumor necrosis factor-TNF | Physiology | Behavior | Endotoxemia | Immune system | NF-κB protein | Cytokines | Astrocytes | Exposure | Injection | Tumor necrosis factor-α | IL-1β | Metabolism | Gene expression | Serum levels | Dentate gyrus | Gliosis | Hospitals | Sepsis | Anesthesiology | Immunoreactivity | Immunofluorescence | Hippocampus | Long-term effects | Animal cognition | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e83072 - e83072
Estrogen is traditionally thought to exert genomic actions through members of the nuclear receptor family. Here, we investigated the rapid nongenomic effects... 
PROTEIN-KINASE-A | RHEUMATOID-ARTHRITIS | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | MEDIATED ACTIVATION | TRAUMA-HEMORRHAGE | GENE-EXPRESSION | SEX STEROIDS | NF-KAPPA-B | RECEPTOR-ALPHA | ANTIINFLAMMATORY CYTOKINES | Phosphorylation | Receptors, Estrogen - metabolism | Receptors, G-Protein-Coupled - metabolism | Calcium - metabolism | Tumor Necrosis Factor-alpha - genetics | Male | Quinolines - pharmacology | Egtazic Acid - analogs & derivatives | p38 Mitogen-Activated Protein Kinases - metabolism | Estradiol - pharmacology | Serum Albumin, Bovine - pharmacology | Receptors, Estrogen - genetics | Mice, Inbred C57BL | Gene Expression Regulation | Receptors, Estrogen - antagonists & inhibitors | p38 Mitogen-Activated Protein Kinases - genetics | Macrophages - cytology | Macrophages - metabolism | Animals | Egtazic Acid - pharmacology | Calcium Signaling - drug effects | Lipopolysaccharides - pharmacology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Macrophages - drug effects | Mice | Receptors, G-Protein-Coupled - genetics | Primary Cell Culture | Tumor Necrosis Factor-alpha - biosynthesis | Benzodioxoles - pharmacology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Transcription factors | Calcium | Estrogens | Estrogen | Estrogen receptors | 17β-Estradiol | Intracellular signalling | Kinases | Macrophages | Calcium influx | Lipopolysaccharides | Calcium signalling | Proteins | Signal transduction | Receptors | Rodents | Bone marrow | Tumor necrosis factor-TNF | Accreditation | Immune system | Calcium (intracellular) | Cytokines | MAP kinase | Forensic medicine | Tumor necrosis factor-α | Trauma | Pathology | Sex hormones | Protein kinase | Rheumatoid arthritis | Intracellular | Laboratory animals | Calcium (extracellular) | Endocrinology | Index Medicus
Journal Article
Journal Article