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index medicus (263) 263
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chemistry, medicinal (205) 205
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humans (160) 160
chemistry, organic (156) 156
porifera - chemistry (141) 141
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biochemistry & molecular biology (91) 91
marine sponge (87) 87
chemistry, multidisciplinary (83) 83
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metabolites (76) 76
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stereoisomerism (70) 70
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drug screening assays, antitumor (66) 66
chemistry, applied (61) 61
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antineoplastic agents - isolation & purification (56) 56
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cell line, tumor (45) 45
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biology (43) 43
structure-activity relationship (43) 43
molecular conformation (42) 42
chemistry (41) 41
inhibitors (40) 40
cyclization (37) 37
cytotoxicity (36) 36
marine natural-products (36) 36
derivatives (35) 35
analysis (34) 34
sesterterpenes - chemical synthesis (33) 33
terpenes (32) 32
microbial sensitivity tests (31) 31
alkaloids (30) 30
cancer (30) 30
inhibitory concentration 50 (30) 30
manoalide (29) 29
organic chemistry (29) 29
terpenoids (29) 29
anti-bacterial agents - chemistry (28) 28
marine biology (28) 28
acid (26) 26
food science & technology (26) 26
fungi (26) 26
identification (26) 26
mass spectrometry (26) 26
antineoplastic agents (25) 25
apoptosis (25) 25
dose-response relationship, drug (25) 25
enzyme inhibitors - pharmacology (25) 25
enzymes (25) 25
research (25) 25
sesquiterpenes - chemistry (25) 25
stereochemistry (25) 25
sesterterpenoids (24) 24
sponges (24) 24
synthesis (24) 24
anti-bacterial agents - pharmacology (23) 23
biological products - chemistry (23) 23
female (23) 23
models, molecular (23) 23
physiological aspects (23) 23
sesterterpenes - metabolism (23) 23
cell proliferation - drug effects (22) 22
phospholipases a - antagonists & inhibitors (22) 22
scalarane sesterterpenes (22) 22
diterpenes - chemistry (21) 21
cell line (20) 20
cells (20) 20
cytotoxic sesterterpenes (20) 20
expression (20) 20
genome mining approach (20) 20
inactivation (20) 20
phospholipases a2 (20) 20
synthase (20) 20
terpenes - chemical synthesis (20) 20
tumor cells, cultured (20) 20
crystallography, x-ray (19) 19
homosteroids - pharmacology (19) 19
sesterterpene synthase (19) 19
chemical properties (18) 18
discovery (18) 18
sesquiterpenes - isolation & purification (18) 18
terpenes - metabolism (18) 18
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Current Organic Chemistry, ISSN 1385-2728, 2019, Volume 23, Issue 22, pp. 2436 - 2468
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 11/2015, Volume 22, Issue 30, pp. 3502 - 3522
Journal Article
Current Organic Chemistry, ISSN 1385-2728, 2018, Volume 22, Issue 24, pp. 2381 - 2393
Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as... 
CYTOTOXIC SCALARANE SESTERTERPENES | biological activity | natural products discovery | scalaranes | linear sesterterpenes norsesterterpenes | NATURAL-PRODUCTS | CHEMISTRY, ORGANIC | antiproliferative | BISHOMOSCALARANE SESTERTERPENES | ANTITUMOR | DISCOVERY | SPONGE | CACOSPONGIA | A-C | INHIBITORS | Sesterterpenes | DERIVATIVES | cytotoxic
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2013, Volume 56, Issue 11, pp. 4701 - 4717
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2011, Volume 50, Issue 40, pp. 9452 - 9455
Journal Article
Journal of Natural Products, ISSN 0163-3864, 01/2018, Volume 81, Issue 1, pp. 2 - 9
Seven new ophiobolins (1–5, 12, and 14) along with the 11 known analogues (6–11, 13, 15–18) were isolated from the ethyl acetate extracts of the liquid and... 
METABOLITES | CHEMISTRY, MEDICINAL | ANALOGS | CONSTITUTION | DRECHSLERA-GIGANTEA | MARINE NATURAL-PRODUCTS | PLANT SCIENCES | ORIGIN | CYTOTOXIC SESTERTERPENES | ORYZAE | PHARMACOLOGY & PHARMACY | INHIBITORS | COCHLIOBOLIN | A549 Cells | MCF-7 Cells | Humans | Sesterterpenes - chemistry | Aspergillus - chemistry | Cell Line, Tumor | HL-60 Cells | Inhibitory Concentration 50 | Sesterterpenes - pharmacology
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2014, Volume 136, Issue 43, pp. 15326 - 15336
Journal Article