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The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2018, Volume 141, Issue 4, pp. 1269 - 1279
The persistence of eosinophils in sputum despite high doses of corticosteroids indicates disease severity in asthmatic patients. Chronic inflamed airways can... 
eosinophil peroxidase | autoimmunity | anti-nuclear antibodies | eosinophilia | sputum | Severe asthma | eosinophil degranulation | autoantibodies | RHEUMATOID-ARTHRITIS | ANTIBODIES | LYMPHOPENIA | NASAL POLYPS | IMMUNOLOGY | PEROXIDASE | B-CELL | ALLERGY | LYMPHOID-TISSUE | DEGRANULATION | T-CELLS | Biomarkers - metabolism | Severity of Illness Index | Autoantibodies - metabolism | Anti-Asthmatic Agents - therapeutic use | Humans | Middle Aged | Male | Asthma - drug therapy | Pulmonary Eosinophilia - drug therapy | Eosinophil Peroxidase - immunology | Sputum - immunology | Asthma - immunology | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Antibodies, Antinuclear - metabolism | Prednisone - therapeutic use | Pulmonary Eosinophilia - immunology | Autoimmunity | Medical research | Care and treatment | Autoantibodies | Corticosteroids | Immunoglobulin G | Medicine, Experimental | Asthma | Corticoids | Identification methods | Antibodies | Lymphocytes T | Thyroid gland | Family medical history | Eotaxin | Interleukin 5 | Bronchitis | Peroxidase | Immunoglobulins | Dexamethasone | Cytokines | Leukocytes (eosinophilic) | Neutrophils | Inflammation | Interleukin 13 | Prednisone | Patients | Immunological tolerance | Interleukin 18 | Studies | Signaling | Lungs | Immunogenicity | Lymphocytes B | Sputum | Degranulation | Eosinophils
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Clinical therapeutics, 08/2019
The goal of this study was to assess the long-term safety and efficacy of mepolizumab in patients with the most severe eosinophilic asthma. This multicenter,... 
Index Medicus
Journal Article
Journal of Asthma, ISSN 0277-0903, 08/2019, Volume 56, Issue 8, pp. 872 - 881
Introduction: Poorly controlled severe eosinophilic asthma is difficult and costly to manage. Reslizumab, an add-on treatment for adults with severe... 
cost-effectiveness | Markov model | Asthma | OMALIZUMAB | SEVERE PERSISTENT | CONVENIENT APPROXIMATION | BENRALIZUMAB | BRONCHIAL THERMOPLASTY | EMERGENCY-DEPARTMENT | ALLERGY | RESPIRATORY SYSTEM | DOUBLE-BLIND | QUALITY-OF-LIFE | UNCONTROLLED ASTHMA | ANAPHYLAXIS | Index Medicus
Journal Article
LANCET, ISSN 0140-6736, 02/2018, Volume 391, Issue 10122, pp. 783 - 800
Asthma-one of the most common chronic, non-communicable diseases in children and adults-is characterised by variable respiratory symptoms and variable airflow... 
MEDICINE, GENERAL & INTERNAL | DOSE INHALED CORTICOSTEROIDS | RISK-FACTORS | EOSINOPHILIC ASTHMA | DOUBLE-BLIND | LUNG-FUNCTION | SEVERE EXACERBATIONS | RELIEVER THERAPY | AIRWAY SMOOTH-MUSCLE | UNCONTROLLED PERSISTENT ASTHMA | BRONCHIAL THERMOPLASTY
Journal Article
Advances in Therapy, ISSN 0741-238X, 7/2018, Volume 35, Issue 7, pp. 1059 - 1068
Journal Article