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sh-ptp2 (98) 98
biochemistry & molecular biology (74) 74
protein tyrosine phosphatase, non-receptor type 11 (65) 65
intracellular signaling peptides and proteins (64) 64
protein tyrosine phosphatases - metabolism (62) 62
protein tyrosine phosphatase, non-receptor type 6 (59) 59
animals (57) 57
phosphorylation (54) 54
humans (53) 53
activation (49) 49
sh2 domain-containing protein tyrosine phosphatases (40) 40
src homology domains (35) 35
protein tyrosine phosphatases - genetics (32) 32
sh2-containing phosphotyrosine phosphatase (32) 32
signal transduction (32) 32
protein-tyrosine-phosphatase (29) 29
kinase (28) 28
mice (28) 28
sh2 domains (28) 28
molecular sequence data (24) 24
amino acid sequence (23) 23
signal-transduction (23) 23
cell line (22) 22
enzyme activation (21) 21
src homology-2 domains (21) 21
cell biology (20) 20
insulin (20) 20
phosphotyrosine phosphatase (20) 20
growth-factor receptor (18) 18
protein binding (18) 18
protein tyrosine phosphatases - chemistry (17) 17
rats (17) 17
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tyrosine - metabolism (16) 16
biophysics (15) 15
shp-2 (15) 15
mutation (14) 14
sh2 domain (14) 14
cells (13) 13
phosphatases (13) 13
syp (13) 13
blotting, western (12) 12
protein tyrosine phosphatases - physiology (12) 12
recombinant fusion proteins - metabolism (11) 11
signal transduction - physiology (11) 11
cells, cultured (10) 10
domains (10) 10
epidermal growth factor - pharmacology (10) 10
expression (10) 10
kinases (10) 10
map kinase (10) 10
phosphotyrosine - metabolism (10) 10
protein conformation (10) 10
proteins (10) 10
base sequence (9) 9
binding (9) 9
catalysis (9) 9
corkscrew (9) 9
crystal-structure (9) 9
insulin - pharmacology (9) 9
male (9) 9
substrate specificity (9) 9
antigens, differentiation (8) 8
beta (8) 8
index medicus (8) 8
insulin-receptor substrate-1 (8) 8
k cq biochemistry & molecular biology (8) 8
models, molecular (8) 8
mutagenesis, site-directed (8) 8
neural cell adhesion molecule l1 (8) 8
phosphatase sh-ptp2 (8) 8
phosphoproteins - metabolism (8) 8
point mutation (8) 8
protein (8) 8
recombinant proteins - metabolism (8) 8
research (8) 8
adaptor proteins, signal transducing (7) 7
cloning, molecular (7) 7
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female (7) 7
genetics & heredity (7) 7
kinetics (7) 7
membrane glycoproteins - metabolism (7) 7
peptide fragments - chemistry (7) 7
receptor (7) 7
shptp2 (7) 7
analysis (6) 6
calcium-calmodulin-dependent protein kinases - metabolism (6) 6
crystallography, x-ray (6) 6
grb2 adaptor protein (6) 6
identification (6) 6
immunology (6) 6
pc12 cells (6) 6
phenols (6) 6
platelet-derived growth factor - pharmacology (6) 6
protein structure, tertiary (6) 6
protein tyrosine phosphatase (6) 6
protein tyrosine phosphatase, non-receptor type 11 - metabolism (6) 6
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JOURNAL OF CHEMICAL INFORMATION AND MODELING, ISSN 1549-9596, 07/2019, Volume 59, Issue 7, pp. 3229 - 3239
Journal Article
Journal Article
Science, ISSN 0036-8075, 1/2002, Volume 295, Issue 5555, pp. 683 - 686
Helicobacter pylori CagA protein is associated with severe gastritis and gastric carcinoma. CagA is injected from the attached Helicobacter pylori into host... 
COS cells | Phenotypes | Phosphorylation | Phosphatases | Transfection | Hepatocytes | Epithelial cells | B lymphocytes | Antibodies | Reports | Cell membranes | SH2-CONTAINING PHOSPHOTYROSINE PHOSPHATASE | TRANSLOCATION | FOCAL ADHESION | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | IV SECRETION | GASTRIC EPITHELIAL-CELLS | SH2 DOMAINS | SH-PTP2 | ANTIGEN | Protein Tyrosine Phosphatase, Non-Receptor Type 11 | Humans | Virulence | Helicobacter pylori - genetics | Helicobacter pylori - pathogenicity | Protein Tyrosine Phosphatases - metabolism | Recombinant Fusion Proteins - metabolism | Phosphotyrosine - metabolism | Protein Tyrosine Phosphatases - antagonists & inhibitors | Protein Tyrosine Phosphatases - chemistry | Protein Tyrosine Phosphatases - genetics | Cell Membrane - metabolism | Dipeptides - pharmacology | Bacterial Proteins - genetics | Enzyme Inhibitors - pharmacology | Gastric Mucosa - enzymology | Intracellular Signaling Peptides and Proteins | Cell Size | Antigens, Bacterial | Gastric Mucosa - cytology | src Homology Domains | Cell Membrane - enzymology | Phenotype | Animals | SH2 Domain-Containing Protein Tyrosine Phosphatases | Bacterial Proteins - metabolism | Mutation | COS Cells | Protein Tyrosine Phosphatase, Non-Receptor Type 6 | Amino Acid Substitution | Helicobacter pylori | Carcinogens | Research | Proteins | Molecular biology | Cells
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 12/2017, Volume 25, Issue 24, pp. 6479 - 6485
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2002, Volume 99, Issue 22, pp. 14428 - 14433
Journal Article
Journal of Molecular Liquids, ISSN 0167-7322, 11/2016, Volume 223, pp. 509 - 515
Src-homology2 (SH2) domain-containing protein tyrosine phosphatase-2 (SHP-2) is a ubiquitously expressed protein-tyrosine phosphatase. SHP-2 is linked to human... 
Molecular dynamics | SPMD | Selectivity | Solution interrupted system | SHP-2 | ACTIVATION | PHOSPHORYLATION | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | IDENTIFICATION | NOONAN-SYNDROME | SH2 DOMAINS | SH2-CONTAINING PHOSPHOTYROSINE PHOSPHATASE | LEUKEMIA | PROTEIN-TYROSINE-PHOSPHATASE | SH-PTP2 | Tyrosine | Phosphatases | Conformational analysis | Force and energy
Journal Article
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, ISSN 0929-6646, 11/2013, Volume 112, Issue 11, pp. 707 - 712
Background/Purpose: Noonan syndrome (NS) is inherited as an autosomal dominant disorder with dysmorphic facies, short stature, and cardiac defects, which can... 
GENOTYPE-PHENOTYPE CORRELATION | MUTANT | DEFECTS | PTPN11 | Egyptian patients | PTPN11 GENE | MEDICINE, GENERAL & INTERNAL | SHP-2 | Noonan syndrome | mutational analysis | MICE | SPECTRUM | PROTEIN-TYROSINE-PHOSPHATASE | SH-PTP2
Journal Article
Journal Article