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Behavioural Brain Research, ISSN 0166-4328, 01/2019, Volume 356, pp. 18 - 40
Alzheimer’s disease (AD) is an enervating and chronic progressive neurodegenerative disorder, occurring frequently in the elderly and adversely affecting... 
Bergenin | SH-SY5Y | Scopolamine | Streptozotocin | Alzheimer’s | Cholinesterase
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2019, Volume 519, Issue 3, pp. 540 - 546
1-Methyl-4-phenylpyridinium (MPP )-treated human neuroblastoma SH-SY5Y cells have been generally accepted as a cellular model for Parkinson's disease. To... 
Metabolome | SH-SY5Y | Mitochondria | Parkinson's disease | MPP | Choline
Journal Article
by Lu, M and Sun, W.-L and Shen, J and Wei, M and Chen, B and Qi, Y.-J and Xu, C.-S
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2018, Volume 22, Issue 22, pp. 7908 - 7915
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 11/2019, p. 110956
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2019, p. 115156
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 12/2018, Volume 66, Issue 49, pp. 12967 - 12977
We investigated the cytoprotective effects of anthocyanins in Aronia melanocarpa against apoptosis induced by Aβ , a key mediator of AD pathophysiology. We... 
homeostasis | Anthocyanins | Mitochondrial dysfunction | Aronia melanocarpa | SH-SY5Y cell | Apoptosis
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 12/2019, Volume 314, p. 108823
Schizophrenia cannot be treated sufficiently with existing antipsychotic drugs. Taken into account that increased Glycogen Synthase Kinase 3 Beta (GSK-3β)... 
Schizophrenia | Famotidine | MK-801 | GSK-3β | SH-SY5Y
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 12/2019, Volume 61, p. 104640
Neuroblastoma is an aggressive form of cancer with high mortality. Hydroxychalcones have received considerable attention because of their cytotoxic activities... 
SH-SY5Y | Mitochondria | Respiratory chain | Hydroxychalcones
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 04/2019, Volume 454, Issue 1-2, pp. 57 - 66
Serum albumin (SA) has been shown to act as a heme scavenger in hemolysis and can protect cell against the toxic effect of heme. However, the mechanism of SA... 
Tyrosine | Bovine serum albumin | SH-SY5Y cells | Heme
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2018, Volume 344, pp. 56 - 73
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) have been associated with conflicting effects within the central nervous system... 
SH-SY5Y | Neuroprotection | Neuroinflammation | Neurotoxicity | HAPI | Statin | Index Medicus
Journal Article
Neurochemical Research, ISSN 0364-3190, 02/2019, Volume 44, Issue 2, pp. 428 - 440
Chronic hypoxic damage is one of the most common pathogenic factors that can cause neurodegenerative disorder in most cases. Etidronate (Eti) is one of the... 
Neuroprotection | Etidronate | TRPC channel | SH-SY5Y cells | Chronic hypoxic damage
Journal Article
CNS and Neurological Disorders - Drug Targets, ISSN 1871-5273, 02/2016, Volume 15, Issue 1, pp. 73 - 79
Journal Article
Molecular Neurodegeneration, ISSN 1750-1326, 01/2017, Volume 12, Issue 1, pp. 1 - 11
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2017, Volume 27, Issue 23, pp. 5207 - 5212
Acacetin (5,7-dihydroxy-4′-methoxyflavone), a flavonoid compound isolated from , chrysanthemum, safflower, and and species has been shown to have anti-cancer... 
Acacetin | Neuronal cell death | SH-SY5Y cells | Parkinson’s disease | 6-Hydroxydopamine
Journal Article
Journal of Trace Elements in Medicine and Biology, ISSN 0946-672X, 09/2019, p. 126406
Journal Article
Journal of Functional Foods, ISSN 1756-4646, 04/2017, Volume 31, pp. 229 - 236
is a traditional folk medicine in China, and its seeds are used to make jelly. Phytochemical investigation of the active ethyl acetate (EtOAc) extract of its... 
SH-SY5Y | Nicandra physaloides | MPP | Phenolic amides
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 12/2019, Volume 678, p. 108181
Isoflurane, one of the commonly used inhalation anesthetics worldwide in clinical practice, may generate substantial risks of neurotoxicity in the developing... 
miR-214 | Neurotoxicity | PTEN/PI3K/Akt pathway | SH-SY5Y cells | Isoflurane
Journal Article
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