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ship2 (132) 132
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phosphatidylinositol-3,4,5-trisphosphate 5-phosphatases (83) 83
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Journal of Cell Science, ISSN 0021-9533, 08/2018, Volume 131, Issue 16, p. jcs216408
Metastasis of breast cancer cells to distant organs is responsible for similar to 50% of breast cancer-related deaths in women worldwide. SHIP2 (also known as... 
Breast cancer cell | Phosphoinositide | SHIP2 | Cell migration | PROTEIN | LIPID PHOSPHATASE SHIP2 | PROLIFERATION | CELL BIOLOGY | OPSISMODYSPLASIA | GENE | CLASS-I | INOSITOL POLYPHOSPHATE 5-PHOSPHATASE | EXPRESSION | N1 GLIOBLASTOMA CELLS | REGULATES PI(3,4)P-2
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 10/2019, Volume 118, p. 109392
Laryngeal squamous cell carcinoma (LSCC) is the major type of laryngeal carcinoma. SHIP2 plays a critical role in malignant tumors and is associated with... 
pAKT | Radiosensitivity | Laryngeal squamous cell carcinoma | SHIP2 | Descending-SHIP2-mediated radiosensitivity enhancement | PI3K/Akt | MEDICINE, RESEARCH & EXPERIMENTAL | PHOSPHATASE SHIP2 | PHARMACOLOGY & PHARMACY | CANCER
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2015, Volume 89, pp. 679 - 689
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2017, Volume 68, Issue 3, pp. 566 - 580.e10
The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P .... 
INPP4B | PI(3,4)P2 | invadopodia | PI3K | SHIP2 | PTEN | prostate | cancer | PI(3,4,5)P3 | PI(3,4,5)P | PI(3,4)P
Journal Article
Carcinogenesis, ISSN 0143-3334, 10/2019, Volume 40, Issue 10, pp. 1198 - 1208
Abstract Copy number variations (CNVs) represent one of the most common genomic alterations. This study aimed to evaluate the roles of genes within highly... 
SURVIVAL | OVEREXPRESSION | METASTASIS | ONCOLOGY | CORTACTIN | GENES | PHOSPHATASE SHIP2 | 11Q13 | CARCINOMA | EXPRESSION | CTTN EMS1
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2009, Volume 158, Issue 3, pp. 879 - 887
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 10/2018, Volume 656, pp. 31 - 37
Journal Article
CHEMBIOCHEM, ISSN 1439-4227, 02/2017, Volume 18, Issue 4, pp. 233 - 247
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 03/2019, Volume 84, pp. 434 - 443
EphA2 receptor plays a critical and debatable function in cancer and is considered a target in drug discovery. Lately, there has been a growing interest in its... 
NMR | SAM domains | SPR | Ship2 | Virtual screening | EphA2 | MST | Cancer | SYSTEM | AUTODOCK VINA | SMALL MOLECULES | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPID PHOSPHATASE SHIP2 | CHEMISTRY, ORGANIC | IDENTIFICATION | OPTIMIZATION | SAM DOMAIN | BINDING | RECEPTOR TYROSINE KINASE | Amino acids | Phosphatases | Drug discovery | Peptides | Analysis
Journal Article
by Zhou, J and Di, MM and Han, H
ONCOTARGETS AND THERAPY, ISSN 1178-6930, 2019, Volume 12, pp. 7067 - 7077
Purpose: Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) gene is associated with arthrosclerosis, gastric cancer and diabetes. In this study, we... 
MIGRATION | APOPTOSIS | CELLS | rat model | SHIP2 | INVOLVEMENT | breast cancer | PHOSPHATASE SHIP2 | PROLIFERATION | Wnt/beta-catenin signaling | OVEREXPRESSION | tumor progression | ONCOLOGY | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DISEASE | EXPRESSION | Wnt/β-catenin signaling
Journal Article
JOURNAL OF CELL BIOLOGY, ISSN 0021-9525, 09/2016, Volume 214, Issue 6, pp. 719 - 734
Invadopodia are specialized membrane protrusions that support degradation of extracellular matrix (ECM) by cancer cells, allowing invasion and metastatic... 
VASP | CYTOSKELETAL | ADHESION | METASTASIS | ACTIN | INOSITOL 5-PHOSPHATASE SHIP2 | CORTACTIN | ENA/VASP PROTEINS | EVH1 DOMAIN | EGF RECEPTOR | CELL BIOLOGY
Journal Article