X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (80677) 80677
Publication (10914) 10914
Newsletter (9891) 9891
Newspaper Article (2268) 2268
Book Chapter (724) 724
Book Review (536) 536
Dissertation (490) 490
Conference Proceeding (302) 302
Book / eBook (112) 112
Magazine Article (106) 106
Transcript (58) 58
Web Resource (52) 52
Trade Publication Article (46) 46
Reference (42) 42
Government Document (18) 18
Streaming Video (16) 16
Data Set (13) 13
Journal / eJournal (5) 5
Paper (3) 3
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
heat shock proteins (39419) 39419
animals (34453) 34453
humans (29573) 29573
index medicus (29034) 29034
biochemistry & molecular biology (16628) 16628
proteins (16387) 16387
heat-shock proteins (13528) 13528
research (13119) 13119
male (12161) 12161
heat-shock proteins - metabolism (11944) 11944
mice (11554) 11554
cell biology (10810) 10810
expression (10682) 10682
heat-shock proteins - genetics (10260) 10260
female (9973) 9973
analysis (9208) 9208
apoptosis (8762) 8762
gene expression (8181) 8181
hsp70 heat-shock proteins - metabolism (8093) 8093
rats (8007) 8007
molecular sequence data (7996) 7996
cancer (6700) 6700
amino acid sequence (6488) 6488
physiological aspects (6428) 6428
oxidative stress (6415) 6415
stress (6090) 6090
hsp70 (5755) 5755
immunology (5724) 5724
hsp70 heat-shock proteins - genetics (5682) 5682
protein binding (5617) 5617
cells (5592) 5592
genes (5447) 5447
molecular chaperones (5348) 5348
heat-shock-protein (5265) 5265
oncology (5013) 5013
research article (4881) 4881
hot temperature (4763) 4763
genetic aspects (4737) 4737
base sequence (4709) 4709
heat shock protein (4705) 4705
microbiology (4664) 4664
cell line (4635) 4635
hsp90 heat-shock proteins - metabolism (4581) 4581
phosphorylation (4482) 4482
gene-expression (4366) 4366
cell line, tumor (4335) 4335
activation (4334) 4334
cells, cultured (4268) 4268
neurosciences (4117) 4117
mutation (4061) 4061
reports (4047) 4047
protein folding (4037) 4037
blotting, western (3949) 3949
signal transduction (3918) 3918
heat shock (3839) 3839
article (3721) 3721
multidisciplinary sciences (3689) 3689
escherichia-coli (3672) 3672
protein (3640) 3640
heat-shock proteins - biosynthesis (3545) 3545
identification (3464) 3464
universities and colleges (3441) 3441
temperature (3414) 3414
gene (3406) 3406
physiology (3401) 3401
biology (3369) 3369
adult (3365) 3365
health aspects (3349) 3349
biochemistry (3335) 3335
hsp90 (3306) 3306
life sciences (3304) 3304
middle aged (3241) 3241
biophysics (3226) 3226
heat-shock protein (3204) 3204
molecular chaperones - metabolism (3199) 3199
induction (3128) 3128
gene expression regulation (3111) 3111
in-vivo (3111) 3111
time factors (3045) 3045
immunohistochemistry (3031) 3031
rna, messenger - metabolism (2927) 2927
binding (2898) 2898
rna (2878) 2878
medicine (2860) 2860
genetics & heredity (2857) 2857
pharmacology & pharmacy (2690) 2690
plant sciences (2670) 2670
molecular chaperone (2578) 2578
apoptosis - drug effects (2558) 2558
genetic research (2542) 2542
heat-shock proteins - chemistry (2524) 2524
transcription factors - metabolism (2520) 2520
in-vitro (2487) 2487
rats, sprague-dawley (2435) 2435
proteomics (2423) 2423
chaperone (2406) 2406
transcription, genetic (2390) 2390
inflammation (2388) 2388
dna-binding proteins - metabolism (2387) 2387
rna, messenger - genetics (2358) 2358
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (53) 53
Gerstein Science - Stacks (25) 25
UofT at Mississauga - Stacks (5) 5
UofT at Scarborough - Stacks (3) 3
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Earth Sciences (Noranda) - Stacks (2) 2
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
UTL at Downsview - May be requested (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (92226) 92226
Chinese (1155) 1155
Japanese (996) 996
Russian (447) 447
Korean (136) 136
German (128) 128
French (122) 122
Polish (90) 90
Spanish (66) 66
Hungarian (24) 24
Portuguese (22) 22
Czech (13) 13
Turkish (12) 12
Dutch (8) 8
Ukrainian (8) 8
Persian (7) 7
Swedish (7) 7
Italian (6) 6
Finnish (4) 4
Bulgarian (3) 3
Slovak (3) 3
Danish (2) 2
Arabic (1) 1
Catalan (1) 1
Croatian (1) 1
Hebrew (1) 1
Latin (1) 1
Lithuanian (1) 1
Serbian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Annual Review of Biochemistry, ISSN 0066-4154, 6/2016, Volume 85, Issue 1, pp. 715 - 742
Molecular chaperones control the cellular folding, assembly, unfolding, disassembly, translocation, activation, inactivation, disaggregation, and degradation... 
Hsp70 | Hsp60 | unfoldases | Hsp104 | sHsps | protein homeostasis | heat-shock proteins | Hsp110 | small heat-shock proteins | Heat-shock proteins | Small heat-shock proteins | SHsps | Unfoldases | Protein homeostasis | BACTERIOPHAGE-LAMBDA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SUBUNIT BINDING-PROTEIN | ALPHA-B-CRYSTALLIN | QUALITY-CONTROL | RIBULOSEBISPHOSPHATE-CARBOXYLASE | HEAT-SHOCK-PROTEIN | ATP HYDROLYSIS | LAMBDA-DNA-REPLICATION | RIBULOSE-BISPHOSPHATE CARBOXYLASE | Protein Aggregates | Rhodospirillum rubrum - metabolism | Protein Unfolding | Humans | Mitochondrial Proteins - genetics | HSP110 Heat-Shock Proteins - chemistry | Mitochondrial Proteins - metabolism | Adenosine Triphosphate - metabolism | Escherichia coli - metabolism | Protein Structure, Quaternary | Chaperonin 60 - metabolism | HSP70 Heat-Shock Proteins - chemistry | Rhodospirillum rubrum - chemistry | Chaperonin 60 - chemistry | Chaperonin 60 - genetics | Gene Expression | Heat-Shock Proteins, Small - chemistry | Heat-Shock Proteins, Small - metabolism | Models, Molecular | HSP70 Heat-Shock Proteins - genetics | Escherichia coli - chemistry | Protein Folding | HSP70 Heat-Shock Proteins - metabolism | HSP110 Heat-Shock Proteins - genetics | Heat-Shock Proteins, Small - genetics | Mitochondrial Proteins - chemistry | Adenosine Triphosphate - chemistry | HSP110 Heat-Shock Proteins - metabolism | Molecular chaperones | Observations | Protein folding | Health aspects
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 02/2015, Volume 40, Issue 2, pp. 117 - 125
•Hsp90 recognises substrate by an extended interface with scattered hydrophobics.•Hsp90 binds folded proteins, folding intermediates, and disordered... 
protein–protein interactions | protein folding | molecular chaperones | Alzheimer disease | heat shock proteins | intrinsically disordered proteins | HSP72 Heat-Shock Proteins | Molecular Chaperones | HSP90 Heat-Shock Proteins | Humans | Intrinsically Disordered Proteins | Protein Binding | Substrate Specificity | Ligands | Alzheimer Disease | Protein Folding | Protein Interaction Maps | Heat shock proteins | Molecular chaperones | Intrinsically disordered proteins | Protein folding | Protein-protein interactions | X-RAY SOLUTION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | STRUCTURAL-ANALYSIS | ESCHERICHIA-COLI HSP90 | POSTTRANSLATIONAL MODIFICATIONS | protein-protein interactions | HEAT-SHOCK-PROTEIN | GLUCOCORTICOID-RECEPTOR | SUBSTRATE-BINDING | N-TERMINAL DOMAIN | MOLECULAR CHAPERONE | Protein Binding - genetics | Molecular Chaperones - metabolism | Molecular Chaperones - genetics | HSP72 Heat-Shock Proteins - metabolism | Molecular Chaperones - chemistry | HSP72 Heat-Shock Proteins - chemistry | Alzheimer Disease - pathology | HSP72 Heat-Shock Proteins - genetics | Protein Interaction Maps - genetics | Intrinsically Disordered Proteins - chemistry | Alzheimer Disease - metabolism | HSP90 Heat-Shock Proteins - chemistry | HSP90 Heat-Shock Proteins - metabolism | HSP90 Heat-Shock Proteins - genetics | Alzheimer Disease - genetics | Intrinsically Disordered Proteins - metabolism | Proteins | Protein binding
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 07/2018, Volume 19, Issue 7, p. 2112
Although the N-terminal domain of vertebrate small heat shock proteins (sHsp) is poorly conserved, it contains a core motif preserved in many members of the... 
Chaperone-like activity | Disease-related mutations | Small heat shock proteins | Oligomer structure | INHERITED PEDIATRIC CATARACT | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | A-CRYSTALLIN | ALPHA-B-CRYSTALLIN | oligomer structure | SUBUNIT EXCHANGE | CHEMISTRY, MULTIDISCIPLINARY | small heat shock proteins | chaperone-like activity | disease-related mutations | CONGENITAL CATARACT | MOTOR NEUROPATHY | MUTATIONS | OLIGOMERIZATION | alpha-Crystallin B Chain - genetics | Crystallins - metabolism | HSP27 Heat-Shock Proteins - chemistry | Humans | Molecular Sequence Data | HSP20 Heat-Shock Proteins - genetics | alpha-Crystallin B Chain - metabolism | HSP20 Heat-Shock Proteins - metabolism | HSP27 Heat-Shock Proteins - genetics | Heat-Shock Proteins - genetics | alpha-Crystallin B Chain - chemistry | Arginine - genetics | Crystallins - chemistry | HSP20 Heat-Shock Proteins - chemistry | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Sequence | Heat-Shock Proteins, Small - chemistry | Heat-Shock Proteins - metabolism | Heat-Shock Proteins, Small - metabolism | Protein-Serine-Threonine Kinases - genetics | Crystallins - genetics | Arginine - chemistry | Amino Acid Motifs - physiology | Heat-Shock Proteins, Small - genetics | Point Mutation | HSP27 Heat-Shock Proteins - metabolism | Protein-Serine-Threonine Kinases - chemistry | Amino Acid Motifs - genetics | Chromatography, Gel | Heat-Shock Proteins - chemistry | Alanine | Fluorescence | Heat shock proteins | Thermal stability | Proteins | Oligomers | Conserved sequence | Arginine | Dimers | Mutation | Destabilization | Heat shock
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 8, pp. 2687 - 2700
The microtubule-associated protein tau forms insoluble, amyloid-type aggregates in various dementias, most notably Alzheimer's disease. Cellular chaperone... 
HEAT-SHOCK PROTEINS | NEUROFIBRILLARY TANGLES | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FRONTOTEMPORAL DEMENTIA | PAIRED HELICAL FILAMENTS | ALPHA-B-CRYSTALLIN | PLASTICITY DEFICITS | BETA-STRUCTURE | AGGREGATION | HSP27 Heat-Shock Proteins - chemistry | HSC70 Heat-Shock Proteins - metabolism | Humans | tau Proteins - metabolism | Amyloid - chemistry | Amyloid - ultrastructure | HSC70 Heat-Shock Proteins - ultrastructure | Recombinant Fusion Proteins - metabolism | tau Proteins - chemistry | HSP27 Heat-Shock Proteins - genetics | HSP27 Heat-Shock Proteins - ultrastructure | Protein Isoforms - metabolism | tau Proteins - genetics | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Protein Aggregation, Pathological - prevention & control | Protein Isoforms - chemistry | Amyloid - drug effects | Protein Interaction Domains and Motifs | Dimerization | Heparin - pharmacology | tau Proteins - ultrastructure | HSC70 Heat-Shock Proteins - genetics | Solubility | Models, Molecular | Recombinant Fusion Proteins - chemistry | Down-Regulation - drug effects | Amino Acid Motifs | Cryoelectron Microscopy | HSC70 Heat-Shock Proteins - chemistry | Anticoagulants - pharmacology | HSP27 Heat-Shock Proteins - metabolism | Kinetics | Mutation | Protein Aggregation, Pathological - metabolism | Amino Acid Substitution | Protein Structure and Folding | amyloid | chaperone | 70 kilodalton heat shock protein (Hsp70) | tau | aggregation | small heat shock protein (sHsp)
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2016, Volume 63, Issue 5, pp. 739 - 752
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 3, pp. 1402 - 1414
Background: There has been an expansion of the number of Hsp70 cochaperones in mammals, providing the opportunity for combinatorial assembly of permutations... 
Protein Complexes | Protein Misfolding | Cochaperones | HIGH-THROUGHPUT SCREEN | MOLECULAR CHAPERONES | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUALITY-CONTROL | Hsp40 | Protein Folding | HSP110 CHAPERONES | HEAT-SHOCK-PROTEIN | NEGATIVE REGULATOR | Isothermal Titration Calorimetry | J-DOMAIN | ATP HYDROLYSIS | STRUCTURAL BASIS | Molecular Chaperone | HSC70 CHAPERONE | ATPases | Protein-Protein Interactions | Adaptor Proteins, Signal Transducing - chemistry | Molecular Chaperones - metabolism | Transcription Factors - chemistry | Humans | Multiprotein Complexes - genetics | Molecular Chaperones - chemistry | DNA-Binding Proteins - metabolism | HSP110 Heat-Shock Proteins - chemistry | Multiprotein Complexes - metabolism | HSP70 Heat-Shock Proteins - chemistry | HSP40 Heat-Shock Proteins - chemistry | Recombinant Proteins - metabolism | HSP40 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - genetics | Molecular Chaperones - genetics | Recombinant Proteins - chemistry | HSP70 Heat-Shock Proteins - genetics | Recombinant Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | HSP70 Heat-Shock Proteins - metabolism | Transcription Factors - metabolism | HSP110 Heat-Shock Proteins - genetics | Multiprotein Complexes - chemistry | Apoptosis Regulatory Proteins | Adaptor Proteins, Signal Transducing - genetics | Adaptor Proteins, Signal Transducing - metabolism | HSP110 Heat-Shock Proteins - metabolism | Protein Binding - physiology | Protein Synthesis and Degradation
Journal Article
Cell Reports, ISSN 2211-1247, 05/2015, Volume 11, Issue 5, pp. 759 - 769
Journal Article
by Lu, X and Kakkar, V
Current Medicinal Chemistry, ISSN 0929-8673, 04/2010, Volume 17, Issue 10, pp. 957 - 973
The highly conserved heat-shock proteins (HSPs) from mammals and microbial reagents are among the immunogenic proteins. Their expression is induced in response... 
Autoimmune | Inflammation | Immune response | Atherosclerosis | Heat shock protein | atherosclerosis | CHEMISTRY, MEDICINAL | autoimmune | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | SERUM-SOLUBLE HEAT-SHOCK-PROTEIN-60 | HUMAN ENDOTHELIAL-CELLS | TOLL-LIKE RECEPTOR-4 | CHLAMYDIA-PNEUMONIAE INFECTION | inflammation | immune response | ACUTE MYOCARDIAL-INFARCTION | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | E-DEFICIENT MICE | NF-KAPPA-B | CORONARY-ARTERY-DISEASE | Chaperonin 10 - physiology | HSP40 Heat-Shock Proteins - metabolism | Atherosclerosis - immunology | Chaperonin 60 - physiology | HSP110 Heat-Shock Proteins - physiology | HSP90 Heat-Shock Proteins - physiology | Heat-Shock Proteins - metabolism | Humans | Heat-Shock Proteins - antagonists & inhibitors | Pregnancy Proteins - metabolism | Suppressor Factors, Immunologic - metabolism | HSP70 Heat-Shock Proteins - metabolism | Atherosclerosis - therapy | Chaperonin 10 - metabolism | HSP40 Heat-Shock Proteins - physiology | HSP27 Heat-Shock Proteins - metabolism | HSP90 Heat-Shock Proteins - metabolism | Pregnancy Proteins - physiology | Suppressor Factors, Immunologic - physiology | HSP70 Heat-Shock Proteins - physiology | Chaperonin 60 - metabolism | HSP27 Heat-Shock Proteins - physiology | HSP110 Heat-Shock Proteins - metabolism | Heat-Shock Proteins - physiology
Journal Article