Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (471) 471
life sciences & biomedicine (413) 413
shp-1 (341) 341
humans (290) 290
animals (275) 275
shp-1 protein (242) 242
phosphorylation (171) 171
mice (162) 162
protein tyrosine phosphatase, non-receptor type 6 - metabolism (159) 159
signal transduction (158) 158
immunology (144) 144
tyrosine (132) 132
proteins (116) 116
biochemistry & molecular biology (106) 106
protein tyrosine phosphatase, non-receptor type 6 (106) 106
intracellular signaling peptides and proteins (101) 101
phosphatases (99) 99
cell biology (97) 97
protein tyrosine phosphatase, non-receptor type 6 - genetics (97) 97
apoptosis (90) 90
kinases (83) 83
male (83) 83
oncology (83) 83
protein tyrosine phosphatases - metabolism (82) 82
female (75) 75
phosphatase (71) 71
protein-tyrosine-phosphatase (69) 69
cell line, tumor (65) 65
protein tyrosine phosphatase, non-receptor type 11 (61) 61
biological and medical sciences (59) 59
gene expression (59) 59
cells, cultured (57) 57
multidisciplinary sciences (54) 54
science & technology - other topics (54) 54
stat3 (52) 52
analysis (51) 51
cancer (51) 51
shp‐1 (49) 49
research article (47) 47
signaling (46) 46
cell proliferation (45) 45
stat3 transcription factor - metabolism (45) 45
rodents (44) 44
cytokines (43) 43
mice, inbred c57bl (43) 43
cell line (42) 42
inflammation (42) 42
lymphocytes t (42) 42
protein tyrosine phosphatases - genetics (42) 42
signal transduction - drug effects (42) 42
medical sciences (41) 41
mutation (40) 40
homology (38) 38
rats (38) 38
biology (37) 37
genetic aspects (37) 37
medicine (37) 37
t cells (37) 37
tumors (37) 37
hematology (36) 36
lymphocytes (36) 36
molecular sequence data (35) 35
protein binding (35) 35
research (34) 34
science (34) 34
cell activation (33) 33
signal transduction - immunology (33) 33
amino acid sequence (32) 32
antigens (32) 32
apoptosis - drug effects (32) 32
pharmacology & pharmacy (31) 31
genes (30) 30
stat3 protein (30) 30
transfection (30) 30
tyrosine - metabolism (29) 29
inhibition (28) 28
macrophages (28) 28
phosphorylation - drug effects (28) 28
shp-2 (28) 28
shp-2 protein (28) 28
src homology domains (28) 28
animal structures (27) 27
cell cycle (27) 27
cell proliferation - drug effects (27) 27
immunoglobulins (27) 27
mice, knockout (27) 27
middle aged (27) 27
receptors, immunologic - metabolism (27) 27
abridged index medicus (26) 26
enzyme activation (26) 26
health aspects (26) 26
ligands (26) 26
medicine, research & experimental (26) 26
research & experimental medicine (26) 26
adult (25) 25
antigens, cd - metabolism (25) 25
fundamental and applied biological sciences. psychology (25) 25
binding sites (24) 24
biophysics (24) 24
genetics & heredity (24) 24
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (591) 591
Chinese (50) 50
French (7) 7
Japanese (3) 3
Spanish (3) 3
Czech (1) 1
Portuguese (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Regorafenib (Stivarga) pharmacologically targets epithelialmesenchymal transition in colorectal cancer
by Fan, Li-Ching and Teng, Hao-Wei and Shiau, Chung-Wai and Tai, Wei-Tien and Hung, Man-Hsin and Yang, Shung-Haur and Jiang, Jeng-Kai and Chen, Kuen-Feng
Oncotarget, 2016, Volume 7, Issue 39, pp. 64136 - 64147
Regorafenib | SHP-1 | CRC | EMT | STAT3
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Erratum: THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1 (Nature Immunology DOI: 10.1038/ni.3692)
by Choi, Seeyoung and Warzecha, Claude and Zvezdova, Ekaterina and Lee, Jan and Argenty, Jérémy and Lesourne, Renaud and Aravind, L and Love, Paul E
Nature immunology, ISSN 1529-2908, 05/2017, Volume 18, Issue 6, pp. 705 - 705
SHP-1 protein | Positive selection | Inhibition
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text ATL-1, an analogue of aspirin-triggered lipoxin A 4, is a potent inhibitor of several steps in angiogenesis induced by vascular endothelial growth factor
by Cezar-De-Mello, P.F.T and Vieira, A.M and Nascimento-Silva, V and Villela, C.G and Barja-Fidalgo, C and Fierro, I.M
British journal of pharmacology, ISSN 0007-1188, 03/2008, Volume 153, Issue 5, pp. 956 - 965
Lipoxins | Angiogenesis | SHP-1 | VEGF
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Correction: Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1
by Song, Shiyu and Su, Zhonglan and Xu, Hui and Niu, Mengyuan and Chen, Xiufang and Min, Haiyan and Zhang, Bin and Sun, Guibo and Xie, Sijing and Wang, Hongwei and Gao, Qian
Cell death & disease, ISSN 2041-4889, 07/2018, Volume 9, Issue 8, pp. 787 - 1
SHP-1 protein | Gastric cancer | Stat3 protein
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Correction: SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling
by Jiang, Linjia and Han, Xue and Wang, Jin and Wang, Chen and Sun, Xiaoqiang and Xie, Jiayi and Wu, Guojin and Phan, Hiep and Liu, Zhenguo and Yeh, Edward T H and Zhang, ChengCheng and Zhao, Meng and Kang, Xunlei
The Journal of experimental medicine, ISSN 0022-1007, 08/2018, Volume 215, Issue 8, pp. 2227 - 2227
SHP-1 protein | Hematopoietic stem cells | Stem cells | Hemopoiesis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Polyphyllin D Shows Anticancer Effect through a Selective Inhibition of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP2)
by Kwon, Se Jeong and Ahn, Dohee and Yang, Hyun-Mo and Kang, Hyo Jin and Chung, Sang J
Molecules (Basel, Switzerland), ISSN 1420-3049, 02/2021, Volume 26, Issue 4, p. 848
Cell proliferation | Phosphorylation | Target recognition | SHP-1 protein | Toxicity | Leukemia | Cytotoxicity | Amino acids | Homology | Drug development | Kinases | Phosphatase | Oleanolic acid | Anticancer properties | Proteins | Tumorigenesis | Growth factors | Tyrosine | Extracellular signal-regulated kinase | Permeability | Lymphoma | Natural products | Antitumor activity | Cancer | Apoptosis | Protein-tyrosine-phosphatase | Tumors | Index Medicus | polyphyllin D | natural products | src homology region 2-containing protein tyrosine phosphatase-2 (SHP2) | leukemia | protein tyrosine phosphatase (PTP) | src homology region 2-domain-containing phosphatase-1 (SHP-1)
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Statement of Retraction. Francesco Oriente, Salvatore Iovino, Serena Cabaro, Angela Cassese, Elena Longobardi, Claudia Miele, Paola Ungaro, Pietro Formisano, Francesco Blasi, and Francesco Beguinot. Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase. Diabetes 2011;60:138-147. DOI: 10.2337/db10-0860. PMID: 20864515
by and American Diabetes Association
Diabetes (New York, N.Y.), ISSN 0012-1797, 02/2019, Volume 68, Issue 2, pp. 465 - 466
Tyrosine | SHP-1 protein | Transcription | Diabetes mellitus | Liver | Insulin | Protein-tyrosine-phosphatase | Statements of Retraction
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Correction to: Natural product pectolinarigenin inhibits osteosarcoma growth and metastasis via SHP-1-mediated STAT3 signaling inhibition
by Zhang, Tao and Li, Suoyuan and Li, Jingjie and Yin, Fei and Hua, Yingqi and Wang, Zhouying and Lin, Binhui and Wang, Hongsheng and Zou, Dongqing and Zhou, Zifei and Xu, Jing and Yi, Chengqing and Cai, Zhengdong
Cell death & disease, ISSN 2041-4889, 09/2018, Volume 9, Issue 9, pp. 902 - 3
SHP-1 protein | Natural products | Osteosarcoma | Stat3 protein | Metastases
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling
by Zhang, Jinyi and Somani, Ally-Khan and Siminovitch, Katherine A
Seminars in immunology, ISSN 1044-5323, 08/2000, Volume 12, Issue 4, pp. 361 - 378
protein-tyrosine phosphatases / signal transduction / lymphocytes / SHP-1 | Signal transduction | SHP-1 | Lymphocytes | Protein-tyrosine phosphatases | Life Sciences & Biomedicine | Immunology | Science & Technology | Signal Transduction - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 | Animals | Lymphocytes - immunology | Humans | SH2 Domain-Containing Protein Tyrosine Phosphatases | Intracellular Signaling Peptides and Proteins | Mice | Immunity | Protein Tyrosine Phosphatase, Non-Receptor Type 6 | Protein Tyrosine Phosphatases - immunology | src Homology Domains | SHP-1 protein | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms
by Presotto, Danilo and Erdes, Efe and Duong, Minh Ngoc and Allard, Mathilde and Regamey, Pierre-Olivier and Quadroni, Manfredo and Doucey, Marie-Agnès and Rufer, Nathalie and Hebeisen, Michael
Frontiers in immunology, ISSN 1664-3224, 11/2017, Volume 8, pp. 1564 - 1564
T cell receptor-peptide-major histocompatibility complex affinity | Hyporesponsiveness | ERK1/2 | SHP-1 and SHP-2 phosphatases | CD3ζ | Cancer immunotherapy | T cell receptor engineering | NY-ESO-1 antigen | Life Sciences & Biomedicine | Immunology | Science & Technology | Antigens | Phosphorylation | Care and treatment | Research | Diagnosis | Autoimmune diseases | T cells | hyporesponsiveness | cancer immunotherapy
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Activation of Siglec-7 results in inhibition of in vitro and in vivo growth of human mast cell leukemia cells
by Landolina, Nadine and Zaffran, Ilan and Smiljkovic, Dubravka and Serrano-Candelas, Eva and Schmiedel, Dominik and Friedman, Sheli and Arock, Michel and Hartmann, Karin and Pikarsky, Eli and Mandelboim, Ofer and Martin, Margarita and Valent, Peter and Levi-Schaffer, Francesca
Pharmacological research, ISSN 1043-6618, 08/2020, Volume 158, pp. 104682 - 104682
Mastocytosis | Activation | Monoclonal antibody | SHP-1 | ITIM | Inhibitory receptor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke
by Peng, Li and Zhou, Yang and Jiang, Ning and Wang, Tingting and Zhu, Jin and Chen, Yanlin and Li, Linyu and Zhang, Jinyan and Yu, Shanshan and Zhao, Yong
Journal of neuroinflammation, ISSN 1742-2094, 03/2020, Volume 17, Issue 1, pp. 81 - 81
Neurosciences | Immunology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Protein Deglycase DJ-1 - metabolism | Rats | Male | Rats, Sprague-Dawley | Inflammation - metabolism | Stroke - metabolism | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Mitochondrial Proteins - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Signal Transduction - physiology | Reperfusion Injury - metabolism | Astrocytes - metabolism | Care and treatment | Immune response | Carrier proteins | Development and progression | Genetic aspects | Health aspects | Reperfusion injury | PARK7 protein | TRAF6 protein | Ischemia | Cytokines | SHP-1 protein | Tumor necrosis factor-TNF | Inflammation | Glucose | Index Medicus | DJ-1 | NLRX1-TRAF6 | Astrocyte | SHP-1 | I/R injury
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text TNFSF15 inhibits VEGF‐stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation
by Yang, Gui-Li and Zhao, Zilong and Qin, Ting-Ting and Wang, Dong and Chen, Lijuan and Xiang, Rong and Xi, Zhen and Jiang, Rongcai and Zhang, Zhi-Song and Zhang, Jianning and Li, Lu-Yuan
The FASEB journal, ISSN 0892-6638, 05/2017, Volume 31, Issue 5, pp. 2001 - 2012
DR3 | vascular integrity | SHP‐1 | SHP-1 | Vascular integrity | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphorylation | Endothelial Cells - metabolism | Humans | Tumor Necrosis Factor Ligand Superfamily Member 15 - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Permeability | Tumor Necrosis Factor Ligand Superfamily Member 15 - metabolism | Tumor Necrosis Factor-alpha | Cell proliferation | Myocardial infarction | Cerebral infarction | Stroke | SHP-1 protein | Blood vessels | Homology | Dephosphorylation | Cell surface | Endothelial cells | Signaling | Ischemia | Tumor necrosis factor | Infarction | Vascular endothelial growth factor | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1
by Chen, Gang and Kim, Yong Ho and Li, Hui and Luo, Hao and Liu, Da-Lu and Zhang, Zhi-Jun and Lay, Mark and Chang, Wonseok and Zhang, Yu-Qiu and Ji, Ru-Rong
Nature neuroscience, ISSN 1097-6256, 06/2017, Volume 20, Issue 7, pp. 917 - 926
Cellular proteins | Care and treatment | Evoked potentials (Electrophysiology) | Development and progression | Genetic aspects | Properties | Chronic pain | Testing | Phosphorylation | Parkinson's disease | SHP-1 protein | PD-1 protein | Activation | Lymphocytes T | Tissues | Immunity | Neuromodulation | Channels | Pain | Dorsal root ganglia | Lymphocytes | Rodents | Inhibition | Movement disorders | Tyrosine | Sodium channels | Pain perception | Neurodegenerative diseases | Neurons | Hypersensitivity | Melanoma | Excitability | Injection | Analgesia | Inhibitors | Sodium | Cell death | PD-L1 protein | Mice | Hyperpolarization | Cancer | Protein-tyrosine-phosphatase | Neutralization | Apoptosis | Index Medicus
Journal Article