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Cancer Letters, ISSN 0304-3835, 2012, Volume 320, Issue 2, pp. 158 - 170
Journal Article
Molecular cancer research : MCR, ISSN 1541-7786, 1/2010, Volume 8, Issue 1, pp. 107 - 118
.... Agents that can suppress STAT3 activation have potential not only for prevention but also for treatment of cancer... 
Plumbagin | JAK2 | SHP-1 | STAT3 | JAK1 | Apoptosis
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e90024
.... Proliferation of numerous cancer cells depends on hEAG1, and in some cases, hERG. hERG is best known for contributing to the cardiac action potential, and for numerous channel mutations that underlie 'long-QT syndrome... 
PROTEIN-KINASE-A | MULTIDISCIPLINARY SCIENCES | GENE POTASSIUM CHANNELS | CARDIAC-ARRHYTHMIA | I-KR | LONG-QT SYNDROME | NATIVE KV1.3 CHANNELS | RECTIFYING K+ CURRENT | INTRAMOLECULAR REGULATION | C-SRC | PHOSPHORYLATION SITES | Humans | Ether-A-Go-Go Potassium Channels - metabolism | Molecular Sequence Data | ERG1 Potassium Channel | HEK293 Cells | src-Family Kinases - metabolism | Conserved Sequence | Cyclic AMP - metabolism | Action Potentials - drug effects | Pyrazoles - pharmacology | Protein Structure, Tertiary | Amino Acid Sequence | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - pharmacology | Signal Transduction | src-Family Kinases - antagonists & inhibitors | Gene Expression Regulation | Rats | Pyrimidines - pharmacology | Ether-A-Go-Go Potassium Channels - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Peptides - pharmacology | Action Potentials - physiology | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Sequence Homology, Amino Acid | Patch-Clamp Techniques | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Protein Binding | Mice | src-Family Kinases - genetics | Tyrosine | Phenols | Genetic aspects | Phosphatases | Phosphotransferases | Cell proliferation | Phosphorylation | SHP-1 protein | Elk | Action potential | Smooth muscle | Kinases | Phosphatase | Tissues | Inflammatory diseases | Proteins | Immunology | Health care networks | Rodents | Prototypes | Post-translation | Physiology | Ion channels | Potassium channels (voltage-gated) | Protein-tyrosine kinase | Heart diseases | Recombinant | Cell survival | Substrate inhibition | Gene expression | Signaling | Lymphomas | Kinetics | Mutation | Autoimmune diseases | Binding sites | Protein-tyrosine-phosphatase | Cancer
Journal Article